ES2232984T3 - Bacteria productora de acido l-glutamico y procedimiento para la preparacion de acido l-glutamico. - Google Patents

Bacteria productora de acido l-glutamico y procedimiento para la preparacion de acido l-glutamico.

Info

Publication number
ES2232984T3
ES2232984T3 ES99105508T ES99105508T ES2232984T3 ES 2232984 T3 ES2232984 T3 ES 2232984T3 ES 99105508 T ES99105508 T ES 99105508T ES 99105508 T ES99105508 T ES 99105508T ES 2232984 T3 ES2232984 T3 ES 2232984T3
Authority
ES
Spain
Prior art keywords
glutamic acid
glutamic
procedure
preparation
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99105508T
Other languages
English (en)
Inventor
Hiroshi Izui
Eiji Ono
Kazuhiko Matsui
Mika Moriya
Hisao Ito
Yoshihiko Hara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Application granted granted Critical
Publication of ES2232984T3 publication Critical patent/ES2232984T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0016—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with NAD or NADP as acceptor (1.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/14—Glutamic acid; Glutamine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/425—Serratia
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/88—Serratia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

EL ACIDO L - GLUTAMICO SE PRODUCE CULTIVANDO EN UN MEDIO LIQUIDO DE CULTIVO UN MICROORGANISMO PERTENECIENTE AL GENERO ENTEROBACTER O SERRATIA Y QUE ES CAPAZ DE PRODUCIR ACIDO L GLUTAMICO, QUE AUMENTA EN UNA ACTIVIDAD DE UNA ENZIMA QUE CATALIZA UNA REACCION PARA LA BIOSINTESIS DEL ACIDO L GLUTAMICO, O QUE DISMINUYE O ES DEFICIENTE EN UNA ACTIVIDAD DE UNA ENZIMA QUE CATALIZA UNA REACCION QUE SE RAMIFICA DE UNA VIA PARA LA BIOSINTESIS DEL ACIDO L - GLUTAMICO Y QUE PRODUCE UN COMPUESTO DISTINTO DEL ACIDO L - GLUTAMICO, Y EXTRAYENDO DEL MEDIO DE CULTIVO EL ACIDO L - GLUTAMICO PRODUCIDO.
ES99105508T 1998-03-18 1999-03-17 Bacteria productora de acido l-glutamico y procedimiento para la preparacion de acido l-glutamico. Expired - Lifetime ES2232984T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP6906898 1998-03-18
JP29712998 1998-10-19

Publications (1)

Publication Number Publication Date
ES2232984T3 true ES2232984T3 (es) 2005-06-01

Family

ID=26410250

Family Applications (2)

Application Number Title Priority Date Filing Date
ES04013665T Expired - Lifetime ES2327838T3 (es) 1998-03-18 1999-03-17 Bacteria productora de acido l-glutamico y procedimiento para la preparacion de acido l-glutamico.
ES99105508T Expired - Lifetime ES2232984T3 (es) 1998-03-18 1999-03-17 Bacteria productora de acido l-glutamico y procedimiento para la preparacion de acido l-glutamico.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES04013665T Expired - Lifetime ES2327838T3 (es) 1998-03-18 1999-03-17 Bacteria productora de acido l-glutamico y procedimiento para la preparacion de acido l-glutamico.

Country Status (13)

Country Link
US (4) US6331419B1 (es)
EP (2) EP0952221B1 (es)
KR (2) KR100626102B1 (es)
CN (1) CN100402657C (es)
AU (1) AU756507B2 (es)
BR (1) BR9901173B1 (es)
DE (2) DE69941137D1 (es)
ES (2) ES2327838T3 (es)
ID (1) ID22246A (es)
MY (1) MY126522A (es)
PE (1) PE20000342A1 (es)
PL (1) PL196781B1 (es)
TW (1) TWI235179B (es)

Families Citing this family (108)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU756507B2 (en) * 1998-03-18 2003-01-16 Ajinomoto Co., Inc. L-glutamic acid-producing bacterium and method for producing L-glutamic acid
AU761990B2 (en) 1998-10-19 2003-06-12 Ajinomoto Co., Inc. L-glutamic acid producing bacterium and process for producing L-glutamic acid
JP4427878B2 (ja) * 1999-08-20 2010-03-10 味の素株式会社 析出を伴う発酵法によるｌ−グルタミン酸の製造法
AU2005200716B2 (en) * 1999-08-20 2008-02-14 Ajinomoto Co., Inc. Method for producing L-glutamic acid by fermentation accompanied by precipitation
JP4560998B2 (ja) * 2001-02-05 2010-10-13 味の素株式会社 発酵法によるｌ−グルタミンの製造法及びｌ−グルタミン生産菌
JP2002238592A (ja) 2001-02-20 2002-08-27 Ajinomoto Co Inc Ｌ−グルタミン酸の製造法
JP4292724B2 (ja) 2001-02-20 2009-07-08 味の素株式会社 有機態窒素含有組成物及びそれを含む肥料
JP4599726B2 (ja) 2001-02-20 2010-12-15 味の素株式会社 Ｌ−グルタミン酸の製造法
JP4599725B2 (ja) * 2001-02-20 2010-12-15 味の素株式会社 Ｌ−グルタミン酸の製造法
US7052883B2 (en) 2001-04-03 2006-05-30 Degussa Ag Process for the production of L-amino acids using strains of the family Enterobacteriaceae that contain an attenuated fruR gene
DE10116518A1 (de) * 2001-04-03 2002-10-17 Degussa Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae
EP1407028B1 (en) * 2001-07-18 2009-06-24 Evonik Degussa GmbH Process for the preparation of l-threonine using strains of the enterobacteriaceae family which contain enhanced suca and sucb genes
US7011957B2 (en) * 2001-09-26 2006-03-14 Northeastern University Isolation and cultivation of microorganisms from natural environments and drug discovery based thereon
US20030059866A1 (en) * 2001-09-26 2003-03-27 Kim Lewis Isolation and cultivation of microorganisms from natural environments and drug discovery based thereon
US20050130256A1 (en) * 2001-09-26 2005-06-16 Northeastern University Isolation and cultivation of microorganisms from natural environments and drug discovery based thereon
JP3932945B2 (ja) 2002-03-27 2007-06-20 味の素株式会社 Ｌ−アミノ酸の製造法
EP1624069A4 (en) 2003-05-07 2011-06-29 Ajinomoto Kk PROCESS FOR THE PREPARATION OF L-GLUTAMINE ACID
JPWO2004111258A1 (ja) * 2003-06-10 2006-07-27 味の素株式会社 Ｌ−グルタミン酸の製造法
US7344874B2 (en) 2004-03-04 2008-03-18 Ajinomoto Co., Inc. L-glutamic acid-producing microorganism and a method for producing L-glutamic acid
US7501282B2 (en) * 2005-02-25 2009-03-10 Ajinomoto Co., Inc. Plasmid autonomously replicable in Enterobacteriaceae family
JP2009118740A (ja) 2006-03-03 2009-06-04 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
EP2351830B1 (en) 2006-03-23 2014-04-23 Ajinomoto Co., Inc. A method for producing an L-amino acid using bacterium of the Enterobacteriaceae family with attenuated expression of a gene coding for small RNA
WO2007119890A1 (en) 2006-04-18 2007-10-25 Ajinomoto Co., Inc. A METHOD FOR PRODUCING AN L-AMINO ACID USING A BACTERIUM OF THE ENTEROBACTERIACEAE FAMILY WITH ATTENUATED EXPRESSION OF THE sfmACDFH-fimZ CLUSTER OR THE fimZ GENE
JP2009165355A (ja) 2006-04-28 2009-07-30 Ajinomoto Co Inc Ｌ−アミノ酸を生産する微生物及びｌ−アミノ酸の製造法
WO2008020654A2 (en) 2006-08-18 2008-02-21 Ajinomoto Co., Inc. An l-glutamic acid producing bacterium and a method for producing l-glutamic acid
JP2010017082A (ja) 2006-10-10 2010-01-28 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
RU2006143864A (ru) 2006-12-12 2008-06-20 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА ENTEROBACTERIACEAE, В КОТОРОЙ ОСЛАБЛЕНА ЭКСПРЕССИЯ ГЕНОВ cynT, cynS, cynX, ИЛИ cynR, ИЛИ ИХ КОМБИНАЦИИ
JP2010041920A (ja) 2006-12-19 2010-02-25 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
WO2008090770A1 (ja) 2007-01-22 2008-07-31 Ajinomoto Co., Inc. Ｌ－アミノ酸を生産する微生物及びｌ－アミノ酸の製造法
JP2010088301A (ja) 2007-02-01 2010-04-22 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
JP2010110216A (ja) 2007-02-20 2010-05-20 Ajinomoto Co Inc Ｌ−アミノ酸または核酸の製造方法
JP2010110217A (ja) 2007-02-22 2010-05-20 Ajinomoto Co Inc Ｌ−アミノ酸生産菌及びｌ−アミノ酸の製造法
JP2010130899A (ja) 2007-03-14 2010-06-17 Ajinomoto Co Inc Ｌ−グルタミン酸系アミノ酸生産微生物及びアミノ酸の製造法
WO2008133131A1 (ja) 2007-04-16 2008-11-06 Ajinomoto Co., Inc. 有機酸の製造方法
JP5218400B2 (ja) 2007-04-17 2013-06-26 味の素株式会社 カルボキシル基を有する酸性物質の製造法
CN101939412B (zh) 2007-09-04 2016-01-20 味之素株式会社 生产氨基酸的微生物以及氨基酸的生产方法
EP2241630B1 (en) 2007-12-06 2016-06-01 Ajinomoto Co., Inc. A method for producing an organic acid
US7953493B2 (en) 2007-12-27 2011-05-31 Ebr Systems, Inc. Optimizing size of implantable medical devices by isolating the power source
JP2011067095A (ja) 2008-01-10 2011-04-07 Ajinomoto Co Inc 発酵法による目的物質の製造法
WO2009093703A1 (ja) 2008-01-23 2009-07-30 Ajinomoto Co., Inc. Ｌ-アミノ酸の製造法
RU2008105793A (ru) 2008-02-19 2009-08-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) Способ конструирования оперонов, содержащих трансляционно сопряженные гены, бактерия, содержащая такой оперон, способ продукции полезного метаболита и способ мониторинга экспрессии гена
WO2009104731A1 (ja) 2008-02-21 2009-08-27 味の素株式会社 Ｌ－システイン生産菌及びｌ－システインの製造法
JP5332237B2 (ja) 2008-03-06 2013-11-06 味の素株式会社 Ｌ−システイン生産菌及びｌ−システインの製造法
KR100955884B1 (ko) 2008-04-07 2010-05-06 고려대학교 산학협력단 살리신을 이용한 엔테로박터 사카자키의 검출방법 및 이를이용한 엔테로박터 사카자키의 선택배지
JP5488467B2 (ja) 2008-09-05 2014-05-14 味の素株式会社 Ｌ−アミノ酸生産菌及びｌ−アミノ酸の製造法
CN102177246B (zh) 2008-09-08 2015-02-11 味之素株式会社 生产l-氨基酸的微生物和l-氨基酸的生产方法
RU2411289C2 (ru) * 2008-09-30 2011-02-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) Бактерия, принадлежащая к роду pantoea, - продуцент l-аспартата или метаболита, являющегося производным l-аспартата, и способ получения l-аспартата или метаболита, являющегося производным l-аспартата
JP2010142200A (ja) 2008-12-22 2010-07-01 Ajinomoto Co Inc Ｌ−リジンの製造法
WO2010084995A2 (en) 2009-01-23 2010-07-29 Ajinomoto Co.,Inc. A method for producing an l-amino acid
JP5359409B2 (ja) 2009-03-12 2013-12-04 味の素株式会社 Ｌ−システイン生産菌及びｌ−システインの製造法
JPWO2011013707A1 (ja) 2009-07-29 2013-01-10 味の素株式会社 Ｌ−アミノ酸の製造法
WO2011021717A2 (en) 2009-08-21 2011-02-24 Ajinomoto Co.,Inc. Method for producing hydroxylated amino acids
ES2646165T3 (es) 2009-11-30 2017-12-12 Ajinomoto Co., Inc. Bacteria que produce L-cisteína y procedimiento para la producción de L-cisteína
RU2460793C2 (ru) 2010-01-15 2012-09-10 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) Способ получения l-аминокислот с использованием бактерий семейства enterobacteriaceae
RU2010101135A (ru) 2010-01-15 2011-07-20 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) (RU) Бактерия семейства enterobacteriaceae - продуцент l-аспартата или метаболитов, производных l-аспартата, и способ получения l-аспартата или метаболитов, производных l-аспартата
JP2013074795A (ja) 2010-02-08 2013-04-25 Ajinomoto Co Inc 変異型ｒｐｓＡ遺伝子及びＬ−アミノ酸の製造法
RU2471868C2 (ru) 2010-02-18 2013-01-10 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) Мутантная аденилатциклаза, днк, кодирующая ее, бактерия семейства enterobacteriaceae, содержащая указанную днк, и способ получения l-аминокислот
RU2482188C2 (ru) 2010-07-21 2013-05-20 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) СПОСОБ ПОЛУЧЕНИЯ L-АРГИНИНА С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ РОДА Escherichia, В КОТОРОЙ ИНАКТИВИРОВАН ОПЕРОН astCADBE
RU2501858C2 (ru) 2010-07-21 2013-12-20 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТЫ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА Enterobacteriaceae
EP2617808B1 (en) 2010-09-14 2016-06-15 Ajinomoto Co., Inc. Sulfur-containing amino acid-producing bacterium and method for producing sulfur-containing amino acids
JP2014036576A (ja) 2010-12-10 2014-02-27 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
JP2014087259A (ja) 2011-02-22 2014-05-15 Ajinomoto Co Inc Ｌ−システイン生産菌及びｌ−システインの製造法
WO2012137689A1 (ja) 2011-04-01 2012-10-11 味の素株式会社 Ｌ－システインの製造法
JP2014131487A (ja) 2011-04-18 2014-07-17 Ajinomoto Co Inc Ｌ−システインの製造法
RU2496867C2 (ru) 2011-04-25 2013-10-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") Способ получения l-аминокислоты семейства глутамата с использованием коринеформной бактерии
BR112013027845A2 (pt) 2011-05-18 2017-01-03 Ajinomoto Kk Imunoestimulante, ração, método para produzir um imunoestimulante, e, método para imunoestimulação
ES2599482T3 (es) 2011-07-29 2017-02-01 Mitsui Chemicals, Inc. Microorganismo que tiene un ciclo de fijación de dióxido de carbono introducido en el mismo
RU2011134436A (ru) 2011-08-18 2013-10-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") Способ получения l-аминокислоты с использованием бактерии семейства enterobacteriaceae, обладающей повышенной экспрессией генов каскада образования флагелл и клеточной подвижности
BR112013016373B1 (pt) 2011-11-11 2021-05-18 Ajinomoto Co., Inc método para produzir uma substância alvo
JP6183358B2 (ja) 2012-05-29 2017-08-23 味の素株式会社 ３−アセチルアミノ−４−ヒドロキシ安息香酸の製造方法
CN104471061B (zh) 2012-05-30 2018-06-22 株式会社普利司通 异戊二烯合酶和其编码基因以及用于产生异戊二烯单体的方法
CN104718292B (zh) 2013-01-24 2019-09-10 三井化学株式会社 导入了二氧化碳固定循环的微生物
MY174741A (en) 2013-01-24 2020-05-13 Mitsui Chemicals Inc Microorganism for production of chemicals derived from acetyl-coa
RU2013118637A (ru) 2013-04-23 2014-10-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА ENTEROBACTERIACEAE, В КОТОРОЙ РАЗРЕГУЛИРОВАН ГЕН yjjK
JP2016165225A (ja) 2013-07-09 2016-09-15 味の素株式会社 有用物質の製造方法
RU2013140115A (ru) 2013-08-30 2015-03-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА Enterobacteriaceae, В КОТОРОЙ НАРУШЕНА ЭКСПРЕССИЯ КЛАСТЕРА ГЕНОВ znuACB
JP2016192903A (ja) 2013-09-17 2016-11-17 味の素株式会社 海藻由来バイオマスからのｌ−アミノ酸の製造方法
RU2628696C1 (ru) 2013-10-02 2017-08-21 Адзиномото Ко., Инк. Способ получения основной аминокислоты (варианты)
RU2013144250A (ru) 2013-10-02 2015-04-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА Enterobacteriaceae, В КОТОРОЙ ОСЛАБЛЕНА ЭКСПРЕССИЯ ГЕНА, КОДИРУЮЩЕГО ФОСФАТНЫЙ ТРАНСПОРТЕР
EP2886651B1 (en) 2013-10-21 2018-08-22 Ajinomoto Co., Inc. Method for producing l-amino acid
MY172689A (en) 2013-11-22 2019-12-10 Ajinomoto Kk Modified isoprene synthase
WO2015080273A1 (ja) 2013-11-28 2015-06-04 味の素株式会社 イソプレンモノマーの製造方法
RU2014105547A (ru) 2014-02-14 2015-08-20 Адзиномото Ко., Инк. СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА ENTEROBACTERIACEAE, ИМЕЮЩЕЙ СВЕРХЭКСПРЕССИРУЕМЫЙ ГЕН yajL
RU2014112066A (ru) 2014-03-28 2015-10-10 Адзиномото Ко., Инк. Способ получения мономерного изопрена
JP2017216881A (ja) 2014-12-26 2017-12-14 味の素株式会社 ジカルボン酸の製造方法
RU2015120052A (ru) 2015-05-28 2016-12-20 Аджиномото Ко., Инк. Способ получения L-аминокислоты с использованием бактерии семейства Enterobacteriaceae, в которой ослаблена экспрессия гена gshA
CN109121422B (zh) 2016-02-25 2021-12-21 味之素株式会社 使用过表达编码铁输出蛋白基因的肠杆菌科的细菌生产l-氨基酸的方法
JP6948595B2 (ja) * 2016-05-31 2021-10-13 東レ株式会社 α−ヒドロムコン酸の製造方法
JP6999090B2 (ja) * 2016-05-31 2022-01-18 東レ株式会社 ３－ヒドロキシアジピン酸の製造方法
JP2019531759A (ja) 2016-10-26 2019-11-07 味の素株式会社 目的物質の製造方法
JP7063332B2 (ja) 2016-10-26 2022-05-09 味の素株式会社 目的物質の製造方法
WO2018079684A1 (en) 2016-10-26 2018-05-03 Ajinomoto Co., Inc. Method for producing objective substance
JP7188385B2 (ja) 2016-10-26 2022-12-13 味の素株式会社 Ｌ－メチオニンまたは合成にｓ－アデノシルメチオニンを要求する代謝物の製造方法
CN109890972B (zh) 2016-10-26 2022-11-08 味之素株式会社 生产目标物质的方法
JP2019536450A (ja) 2016-10-27 2019-12-19 味の素株式会社 アルデヒドの製造方法
JP7066977B2 (ja) 2017-04-03 2022-05-16 味の素株式会社 Ｌ－アミノ酸の製造法
US10858676B2 (en) 2017-05-22 2020-12-08 Ajinomoto Co., Inc. Method for producing objective substance
US11680279B2 (en) 2017-11-29 2023-06-20 Ajinomoto Co., Inc. Method for producing objective substance
EP3756466A4 (en) 2018-02-20 2021-11-24 Ajinomoto Co., Inc. METHOD FOR INDUCING RNA SILENCING
WO2020027251A1 (en) 2018-08-03 2020-02-06 Ajinomoto Co., Inc. Method for producing objective substance
WO2020071538A1 (en) 2018-10-05 2020-04-09 Ajinomoto Co., Inc. Method for producing target substance by bacterial fermentation
WO2020171227A1 (en) 2019-02-22 2020-08-27 Ajinomoto Co., Inc. METHOD FOR PRODUCING L-AMINO ACIDS USING A BACTERIUM BELONGING TO THE FAMILY Enterobacteriaceae HAVING OVEREXPRESSED ydiJ GENE
EP3960870A4 (en) 2019-03-29 2023-06-07 Ajinomoto Co., Inc. PROCESS FOR PRODUCTION OF ALLOLACTOSE
JP7524909B2 (ja) 2019-04-05 2024-07-30 味の素株式会社 Ｌ－アミノ酸の製造方法
JPWO2020226087A1 (es) 2019-05-08 2020-11-12
JP7655312B2 (ja) 2019-09-25 2025-04-02 味の素株式会社 細菌の発酵によるｌ－アミノ酸の製造方法
EP4034668B1 (en) 2019-09-25 2024-04-17 Ajinomoto Co., Inc. Method for producing 2-methyl-butyric acid by bacterial fermentation
US20240117393A1 (en) 2022-09-30 2024-04-11 Ajinomoto Co., Inc. Method for producing l-amino acid

Family Cites Families (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS329393B1 (es) 1954-12-25 1957-11-07
GB864562A (en) 1957-08-16 1961-04-06 Ajinomoto Kk A process for the production of glutamic acid or a salt thereof
US3220929A (en) 1964-02-10 1965-11-30 Kyowa Hakko Kogyo Kk Microbiological production of amino acid by reductive amination
US3563857A (en) * 1967-03-20 1971-02-16 Sanraku Ocean Co Process for producing l-glutamic acid by fermentation
JPH0321160B2 (es) * 1979-05-02 1991-03-22 Nat Res Dev
GB2076853B (en) * 1980-04-17 1983-12-21 Ajinomoto Kk L-glutamic acid producing microorganisms
JPS589693A (ja) * 1981-07-03 1983-01-20 Tanabe Seiyaku Co Ltd 発酵法によるｌ−グルタミン酸の製法
JPH0783714B2 (ja) 1983-08-29 1995-09-13 味の素株式会社 発酵法によるｌ―アミノ酸の製造法
JPH0746994B2 (ja) * 1984-10-04 1995-05-24 味の素株式会社 発酵法によるｌ−アミノ酸の製造法
FR2575492B1 (fr) 1984-12-27 1988-09-16 Asahi Chemical Ind Fragment d'adn contenant un gene codant pour la glutamate deshydrogenase, adn recombinant le contenant, et microorganisme contenant l'adn recombinant
FR2581653B1 (fr) 1985-05-10 1989-06-30 Asahi Chemical Ind Fragment d'adn contenant un gene codant pour la phosphoenolpyruvate carboxylase, adn recombinant le contenant et micro-organisme contenant ce dernier
JPS62201585A (ja) 1985-11-26 1987-09-05 Asahi Chem Ind Co Ltd クエン酸合成酵素産生遺伝子を含むｄｎａ断片
JPH07121228B2 (ja) 1986-11-07 1995-12-25 協和醗酵工業株式会社 Ｌ−グルタミン酸およびｌ−プロリンの製造法
JP2520895B2 (ja) * 1987-03-04 1996-07-31 旭化成工業株式会社 Ｌ―グルタミン酸の製造方法
BR9203053A (pt) 1991-08-07 1993-03-30 Ajinomoto Kk Processo para produzir acido l-glutamico pro fermentacao
US5876983A (en) * 1993-08-24 1999-03-02 Ajinomoto Co., Inc. Mutant phosphoenolpyruvate carboxylase, its gene, and production method of amino acid
SK283058B6 (sk) 1993-10-28 2003-02-04 Ajinomoto Co., Inc. Spôsob produkcie cieľovej látky použitím mikroorganizmov
JP3880636B2 (ja) 1994-01-10 2007-02-14 味の素株式会社 発酵法によるｌ−グルタミン酸の製造法
RU2084520C1 (ru) 1994-01-19 1997-07-20 Всесоюзный научно-исследовательский институт генетики и селекции промышленных микроорганизмов Штамм бактерий brevibacterium flavum - продуцент l-глутамина (варианты)
JP2781954B2 (ja) 1994-03-04 1998-07-30 メック株式会社 銅および銅合金の表面処理剤
US5821351A (en) 1994-06-10 1998-10-13 Dnx Biotherapeutics Production of hemoglobin having a delta-like globin
US5977331A (en) * 1994-06-14 1999-11-02 Ajinomoto Co., Inc. α-Ketoglutarate dehydrogenase gene
EP0692539B1 (en) * 1994-07-11 1999-09-22 Kyowa Hakko Kogyo Co., Ltd. Process for producing an optically active gamma-hydroxy-L-glutamic acid
EP1293560B1 (en) * 1994-08-19 2007-11-14 Ajinomoto Co., Inc. Methods for producing L-lysine and L-glutamic acid by fermentation
CN1193343A (zh) * 1995-08-23 1998-09-16 味之素株式会社 通过发酵制备l－谷氨酸的方法
JPH09285294A (ja) * 1996-04-23 1997-11-04 Ajinomoto Co Inc 発酵法によるｌ−グルタミン酸の製造法
AU746542B2 (en) * 1998-03-18 2002-05-02 Ajinomoto Co., Inc. L-glutamic acid-producing bacterium and method for producing L-glutamic acid
AU756507B2 (en) 1998-03-18 2003-01-16 Ajinomoto Co., Inc. L-glutamic acid-producing bacterium and method for producing L-glutamic acid
AU761990B2 (en) 1998-10-19 2003-06-12 Ajinomoto Co., Inc. L-glutamic acid producing bacterium and process for producing L-glutamic acid
JP4427878B2 (ja) * 1999-08-20 2010-03-10 味の素株式会社 析出を伴う発酵法によるｌ−グルタミン酸の製造法
TWI289604B (en) * 1999-10-04 2007-11-11 Ajinomoto Kk neform bacteria Genes for a heat resistant enzymes of amino acid biosynthetic pathway derived from thermophilic cory
JP4304837B2 (ja) * 2000-07-05 2009-07-29 味の素株式会社 Ｌ−グルタミン酸生産菌及びｌ−グルタミン酸の製造法
JP4560998B2 (ja) * 2001-02-05 2010-10-13 味の素株式会社 発酵法によるｌ−グルタミンの製造法及びｌ−グルタミン生産菌
JP4292724B2 (ja) * 2001-02-20 2009-07-08 味の素株式会社 有機態窒素含有組成物及びそれを含む肥料
JP2002238592A (ja) * 2001-02-20 2002-08-27 Ajinomoto Co Inc Ｌ−グルタミン酸の製造法
JP4599726B2 (ja) * 2001-02-20 2010-12-15 味の素株式会社 Ｌ−グルタミン酸の製造法
JP4599725B2 (ja) * 2001-02-20 2010-12-15 味の素株式会社 Ｌ−グルタミン酸の製造法
RU2230114C2 (ru) * 2001-11-30 2004-06-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" Мутантная глутаминсинтетаза, фрагмент днк, штамм escherichia coli - продуцент l-глутамина и способ получения l-аминокислот
JP3932945B2 (ja) * 2002-03-27 2007-06-20 味の素株式会社 Ｌ−アミノ酸の製造法
US7344874B2 (en) * 2004-03-04 2008-03-18 Ajinomoto Co., Inc. L-glutamic acid-producing microorganism and a method for producing L-glutamic acid
US7205132B2 (en) * 2004-09-10 2007-04-17 Ajinomoto Co., Inc. L-glutamic acid-producing microorganism and a method for producing L-glutamic acid
US7794989B2 (en) * 2004-12-28 2010-09-14 Ajinomoto Co., Inc. L-glutamic acid-producing microorganism and a method for producing L-glutamic acid
US7501282B2 (en) * 2005-02-25 2009-03-10 Ajinomoto Co., Inc. Plasmid autonomously replicable in Enterobacteriaceae family
JP5011675B2 (ja) * 2005-08-09 2012-08-29 味の素株式会社 物質の生産プロセスのシミュレーション方法
WO2007024010A1 (ja) * 2005-08-26 2007-03-01 Ajinomoto Co., Inc. Ｌ−グルタミン酸生産菌及びｌ−グルタミン酸の製造方法
JP2007117082A (ja) * 2005-09-27 2007-05-17 Ajinomoto Co Inc Ｌ−アミノ酸生産菌及びｌ−アミノ酸の製造法
WO2008020654A2 (en) * 2006-08-18 2008-02-21 Ajinomoto Co., Inc. An l-glutamic acid producing bacterium and a method for producing l-glutamic acid

Also Published As

Publication number Publication date
MY126522A (en) 2006-10-31
ID22246A (id) 1999-09-23
KR100626102B1 (ko) 2006-09-20
EP1462523B1 (en) 2009-07-15
ES2327838T3 (es) 2009-11-04
TWI235179B (en) 2005-07-01
BR9901173A (pt) 2000-03-28
EP0952221A3 (en) 2001-09-12
US20010019836A1 (en) 2001-09-06
US20090263874A1 (en) 2009-10-22
EP1462523A2 (en) 2004-09-29
PE20000342A1 (es) 2000-04-24
EP1462523A3 (en) 2004-11-17
KR100626568B1 (ko) 2006-09-25
AU756507B2 (en) 2003-01-16
KR20060061785A (ko) 2006-06-08
PL332072A1 (en) 1999-09-27
US20030119153A1 (en) 2003-06-26
AU2122399A (en) 1999-09-30
US8129151B2 (en) 2012-03-06
DE69941137D1 (de) 2009-08-27
CN100402657C (zh) 2008-07-16
KR19990077973A (ko) 1999-10-25
PL196781B1 (pl) 2008-01-31
DE69921881T2 (de) 2005-07-21
DE69921881D1 (de) 2004-12-23
BR9901173B1 (pt) 2010-11-30
CN1233660A (zh) 1999-11-03
EP0952221B1 (en) 2004-11-17
EP0952221A2 (en) 1999-10-27
US6331419B1 (en) 2001-12-18

Similar Documents

Publication Publication Date Title
ES2232984T3 (es) Bacteria productora de acido l-glutamico y procedimiento para la preparacion de acido l-glutamico.
BR9901174A (pt) Microorganismo pertencente ao gênero klebsiella, ao gênero erwinia ou ao gênero pantoea e processo para produzir ácido l-glutâmico
ES2104608T3 (es) Procedimiento para la produccion de una composicion que contiene zeaxantina utilizando un microorganismo de la especie flavobacterium multivorum.
DK1651758T3 (da) Fremgangsmåde tl fremstilling af L-lysin eller L-threonin ved anvendelse af Escherichia bakterier med svækket æblesyreenzymaktivitet
BR0300978A (pt) Método para a produção de um l-aminoácido
PE33496A1 (es) Gen de la deshidrogenasa de alfa-cetoglutarato
BR9904747A (pt) Microorganismo, e, processo para prodizir ácido l-glutâmico
PE20020951A1 (es) Metodo para producir acido l-glutamico
ES2194030T3 (es) Procedimiento para la preparacion de acido l-glutamico mediante fermentacion.
ATE531803T1 (de) Fermentierungsverfahren mittels veränderter bakterien mit einer erhöhten aufnahme von nebenprodukten
ATE373715T1 (de) Isoprenoid biosynthese
BR0106255A (pt) Método papa produzir uma substância alvo pela utilização de um microorganismo
UA90479C2 (en) Biochemical synthesis of 1.4-butane diamine
DE69735059D1 (de) Erhöhte produktion von taxanen durch zellkulturen von taxus-arten
BR0011283A (pt) Processo para a preparaçâo fermentativa de l-aminoácidos com amplificação do gene zwf
DE69917061D1 (de) Nitrocumarine für den nachweis aller mikroorganismen
ES2096095T3 (es) Procedimiento de fermentacion para producir natamicina.
BR0010713A (pt) Processo para a preparação fermentativa de l-aminoácidos com amplificação do gene tkt
ATE274575T1 (de) Prozess zur fermentativen herstellung von d- pantothensäure mit coryneformen bakterien
AU2003273521A1 (en) Production method of iturin a and its homologues
BR0005307A (pt) Processo para a produção fermentativa de l-lisina usando bactérias coryneform
BR0004000A (pt) Processo para a preparação fermentativa de ácido d-pantotênico usando bactéria corineforme
RU2225881C2 (ru) Способ получения l-глутаминовой кислоты
WO2003083123A3 (de) Verbessertes verfahren zur herstellung von vitamin b12
MX166883B (es) Procedimiento microbiologico para la produccion de acido-glutamico