ATE374210T1 - Verfahren zur identifikation von modulatoren von hif-1-alpha - Google Patents

Verfahren zur identifikation von modulatoren von hif-1-alpha

Info

Publication number: ATE374210T1
Authority: AT; Austria
Prior art keywords: alpha; human hif; essentially; domain; hif
Prior art date: 1998-11-13

Application number

AT99958594T

Other languages

English (en)

Inventor

Anders Berkenstam

Lorenz Poellinger

Original Assignee

Angiogenetics Sweden Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-11-13

Filing date

1999-11-11

Publication date

2007-10-15

1999-11-11 Application filed by Angiogenetics Sweden Ab filed Critical Angiogenetics Sweden Ab

2007-10-15 Application granted granted Critical

2007-10-15 Publication of ATE374210T1 publication Critical patent/ATE374210T1/de

Links

101001046870 Homo sapiens Hypoxia-inducible factor 1-alpha Proteins 0.000 abstract 8
102000049131 human HIF1A Human genes 0.000 abstract 8
150000001413 amino acids Chemical class 0.000 abstract 4
150000001875 compounds Chemical class 0.000 abstract 3
102000040945 Transcription factor Human genes 0.000 abstract 2
108091023040 Transcription factor Proteins 0.000 abstract 2
230000003081 coactivator Effects 0.000 abstract 2
210000004899 c-terminal region Anatomy 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000035772 mutation Effects 0.000 abstract 1
230000030648 nucleus localization Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Toxicology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Investigating Or Analysing Biological Materials (AREA)
Peptides Or Proteins (AREA)
Amplifiers (AREA)
Semiconductor Lasers (AREA)
Radar Systems Or Details Thereof (AREA)
Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
Testing, Inspecting, Measuring Of Stereoscopic Televisions And Televisions (AREA)

AT99958594T 1998-11-13 1999-11-11 Verfahren zur identifikation von modulatoren von hif-1-alpha ATE374210T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE9803891A SE9803891D0 (sv)	1998-11-13	1998-11-13	Protein Variants

Publications (1)

Publication Number	Publication Date
ATE374210T1 true ATE374210T1 (de)	2007-10-15

Family

ID=20413284

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99958594T ATE374210T1 (de)	1998-11-13	1999-11-11	Verfahren zur identifikation von modulatoren von hif-1-alpha

Country Status (15)

Country	Link
EP (1)	EP1141005B1 (de)
JP (1)	JP2002530063A (de)
KR (1)	KR100648761B1 (de)
CN (1)	CN1330666C (de)
AT (1)	ATE374210T1 (de)
AU (1)	AU761594B2 (de)
BR (1)	BR9915263A (de)
CA (1)	CA2350830A1 (de)
DE (1)	DE69937199D1 (de)
HK (1)	HK1043372B (de)
NZ (1)	NZ511450A (de)
SE (1)	SE9803891D0 (de)
TR (1)	TR200101345T2 (de)
WO (1)	WO2000029437A1 (de)
ZA (1)	ZA200103669B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9911047D0 (en)	1999-05-12	1999-07-14	Isis Innovation	Assay method and means
ATE383877T1 (de) *	1999-06-04	2008-02-15	Dana Farber Cancer Inst Inc	Identifikation von stoffen, die transkriptionelle antworten auf hypoxia modifizieren
WO2001092578A2 (en) *	2000-05-26	2001-12-06	Board Of Trustees Of The University Of Illinois	Reagents and methods for identifying and modulating expression of genes regulated by retinoids
AU9017901A (en) *	2000-08-07	2002-02-18	Angiogenetics Sweden Ab	Mechanism of conditional regulation of the hypoxia-inducible factor-1 by the vonhippel-lindau tumor suppressor protein
US20030045830A1 (en) *	2001-04-17	2003-03-06	De Bizemont Therese	Gene therapy with chimeric oligonucleotides delivered by a method comprising a step of iontophoresis
AU2002302252A1 (en)	2001-05-23	2002-12-03	Angiogene Inc.	Hypoxia inducible factors and uses thereof for inducing angiogenesis and improving muscular functions
EP1842856A3 (de) *	2001-05-23	2007-12-12	Angiogene Inc.	Hypoxieerzeugende Faktoren und ihre Verwendung zur Herbeiführung von Angiogenese und Verbesserung der Muskelfunktionen
AU2003201798A1 (en) *	2002-01-11	2003-09-02	Angio Genetics Sweden Ab	Hif-1 alpha proteins mutated in the c-terminal transactivation domain
CN100366747C (zh) *	2005-03-08	2008-02-06	上海第二医科大学附属仁济医院	低氧诱导因子小干扰rna质粒
CN100418574C (zh) *	2005-10-26	2008-09-17	王成球	一类封闭人类HIF-1α基因和调控网络中下游相关基因的染色质肽
CN102127161B (zh) *	2010-12-16	2013-03-27	何明忠	抗肿瘤多肽及其用途
CN106366173A (zh) *	2015-07-24	2017-02-01	北京京爱康科技有限公司	一种通过结合低氧反应元件控制缺氧反应基因表达的染色质肽

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5882914A (en) *	1995-06-06	1999-03-16	The Johns Hopkins University School Of Medicine	Nucleic acids encoding the hypoxia inducible factor-1

1998
- 1998-11-13 SE SE9803891A patent/SE9803891D0/xx unknown
1999
- 1999-11-11 WO PCT/SE1999/002053 patent/WO2000029437A1/en not_active Ceased
- 1999-11-11 KR KR1020017005928A patent/KR100648761B1/ko not_active Expired - Fee Related
- 1999-11-11 JP JP2000582422A patent/JP2002530063A/ja active Pending
- 1999-11-11 DE DE69937199T patent/DE69937199D1/de not_active Expired - Lifetime
- 1999-11-11 CN CNB99814388XA patent/CN1330666C/zh not_active Expired - Fee Related
- 1999-11-11 CA CA002350830A patent/CA2350830A1/en not_active Abandoned
- 1999-11-11 TR TR2001/01345T patent/TR200101345T2/xx unknown
- 1999-11-11 AU AU15931/00A patent/AU761594B2/en not_active Ceased
- 1999-11-11 AT AT99958594T patent/ATE374210T1/de not_active IP Right Cessation
- 1999-11-11 EP EP99958594A patent/EP1141005B1/de not_active Expired - Lifetime
- 1999-11-11 BR BR9915263-0A patent/BR9915263A/pt not_active Application Discontinuation
- 1999-11-11 HK HK02105080.8A patent/HK1043372B/zh not_active IP Right Cessation
- 1999-11-11 NZ NZ511450A patent/NZ511450A/en unknown
2001
- 2001-05-07 ZA ZA200103669A patent/ZA200103669B/en unknown

Also Published As

Publication number	Publication date
ZA200103669B (en)	2002-05-07
SE9803891D0 (sv)	1998-11-13
BR9915263A (pt)	2001-10-30
EP1141005A1 (de)	2001-10-10
HK1043372A1 (en)	2002-09-13
KR20010080411A (ko)	2001-08-22
CN1330666C (zh)	2007-08-08
AU761594B2 (en)	2003-06-05
KR100648761B1 (ko)	2006-11-23
WO2000029437A1 (en)	2000-05-25
CA2350830A1 (en)	2000-05-25
JP2002530063A (ja)	2002-09-17
HK1043372B (zh)	2008-05-09
DE69937199D1 (de)	2007-11-08
NZ511450A (en)	2003-08-29
CN1330663A (zh)	2002-01-09
EP1141005B1 (de)	2007-09-26
TR200101345T2 (tr)	2001-10-22
AU1593100A (en)	2000-06-05

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Legal Events

Date	Code	Title	Description
2008-03-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties