|
ES2324280T3
(es)
|
2000-03-14 |
2009-08-04 |
Unilever N.V. |
Dominios variables de la cadena pesada de anticuerpos frente a lipasas dieteticas humanas y sus usos.
|
|
JP4213586B2
(ja)
*
|
2001-09-13 |
2009-01-21 |
株式会社抗体研究所 |
ラクダ抗体ライブラリーの作製方法
|
|
CA2471645A1
(en)
*
|
2002-01-03 |
2003-07-10 |
Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw |
Immunoconjugates useful for treatment of tumours
|
|
AU2003205615B2
(en)
|
2002-01-10 |
2008-09-25 |
Universiteit Gent |
A novel splice variant of MyD88 and uses thereof
|
|
WO2004041863A2
(en)
|
2002-11-08 |
2004-05-21 |
Ablynx N.V. |
Single domain antibodies directed against interferon- gamma and uses therefor
|
|
EP1558645B1
(de)
|
2002-11-08 |
2011-07-27 |
Ablynx N.V. |
Stabilisierte einzel-domänen-antikörper in einer pharmazeutischen zusammensetzung ausgestaltet für inhalation
|
|
EP1900753B1
(de)
|
2002-11-08 |
2017-08-09 |
Ablynx N.V. |
Verfahren zur Verabreichung therapeutischer Polypeptide und Polypeptide dafür
|
|
JP2006517789A
(ja)
|
2003-01-10 |
2006-08-03 |
アブリンクス エン.ヴェー. |
治療用ポリペプチド、その相同物、その断片、および血小板媒介凝集の調節での使用
|
|
ATE485307T1
(de)
|
2003-11-07 |
2010-11-15 |
Ablynx Nv |
Camelidae schwere ketten antikörper vhhs gegen epidermalen wachstumfaktor rezeptor (egfr) und ihre verwendung
|
|
US7785903B2
(en)
|
2004-04-09 |
2010-08-31 |
Genentech, Inc. |
Variable domain library and uses
|
|
EP2371390A3
(de)
|
2004-10-08 |
2013-03-13 |
Domantis Limited |
Antagonisten und Verwendungsverfahren dafür
|
|
WO2006074947A2
(en)
|
2005-01-14 |
2006-07-20 |
Ablynx N.V. |
METHODS AND ASSAYS FOR DISTINGUISHING BETWEEN DIFFERENT FORMS OF DISEASES AND DISORDERS CHARACTERIZED BY THROMBOCYTOPENIA AND/OR BY SPONTANEOUS INTERACTION BETWEEN VON WILLEBRAND FACTOR (vWF) AND PLATELETS
|
|
US8188223B2
(en)
|
2005-05-18 |
2012-05-29 |
Ablynx N.V. |
Serum albumin binding proteins
|
|
ES2694247T3
(es)
|
2005-05-20 |
2018-12-19 |
Ablynx N.V. |
NanobodiesTM mejorados para el tratamiento de trastornos mediados por agregación
|
|
WO2007082899A1
(en)
|
2006-01-17 |
2007-07-26 |
Vib Vzw |
Inhibitors of prolyl-hydroxylase 1 for the treatment of skeletal muscle degeneration
|
|
TW200744634A
(en)
*
|
2006-02-21 |
2007-12-16 |
Wyeth Corp |
Methods of using antibodies against human IL-22
|
|
TWI417301B
(zh)
|
2006-02-21 |
2013-12-01 |
Wyeth Corp |
對抗人類介白素-22(il-22)之抗體及其用途
|
|
EP2073898A1
(de)
|
2006-10-10 |
2009-07-01 |
Academisch Ziekenhuis Bij De Universiteit Van Amsterdam |
Komplementhemmung für verbesserte nervenregeneration
|
|
GB0621513D0
(en)
|
2006-10-30 |
2006-12-06 |
Domantis Ltd |
Novel polypeptides and uses thereof
|
|
WO2008055924A1
(en)
|
2006-11-07 |
2008-05-15 |
Vib Vzw |
Diagnosis and treatment of t-cell acute lymphoblastic leukemia
|
|
MX2009005466A
(es)
|
2006-11-22 |
2009-08-17 |
Adnexus A Bristol Myers Sqibb |
Terapeuticos dirigidos a base de proteinas manipuladas para receptores de tirosina cinasas, incluyendo receptor de factor de crecimiento tipo insulina-i.
|
|
CA2673331A1
(en)
|
2006-12-19 |
2008-06-26 |
Ablynx N.V. |
Amino acid sequences directed against gpcrs and polypeptides comprising the same for the treatment of gpcr-related diseases and disorders
|
|
EP2102244A2
(de)
|
2006-12-19 |
2009-09-23 |
Ablynx N.V. |
Gegen metalloproteinase aus der adam-familie gerichtete aminosäuresequenzen und diese enthaltende polypeptide zur behandlung von mit adam in zusammenhang stehenden krankheiten und störungen
|
|
PL2308514T3
(pl)
|
2007-03-23 |
2013-11-29 |
To Bbb Holding B V |
Koniugaty do ukierunkowanego dostarczania leku poprzez barierę krew-mózg
|
|
AU2008270274B2
(en)
|
2007-07-03 |
2012-06-28 |
Ablynx N.V. |
Providing improved immunoglobulin sequences by mutating CDR and/or FR positions
|
|
BRPI0820327A2
(pt)
|
2007-11-02 |
2020-10-06 |
Novartis Ag |
moléculas e métodos para modulação de proteína relacionada ao receptor de lipoproteína de baixa densidade 6 (lrp6)
|
|
EP2650311A3
(de)
|
2007-11-27 |
2014-06-04 |
Ablynx N.V. |
Gegen heterodimere Cytokine und/oder deren Rezeptoren gerichtete Aminosäuresequenzen und Polypeptide damit
|
|
GB0800277D0
(en)
|
2008-01-08 |
2008-02-13 |
Imagination Tech Ltd |
Video motion compensation
|
|
GB2470328A
(en)
|
2008-03-05 |
2010-11-17 |
Ablynx Nv |
Novel antigen binding dimer complexes, methods of making and uses thereof
|
|
KR101568042B1
(ko)
|
2008-03-31 |
2015-11-10 |
가부시끼가이샤 히다치 세이사꾸쇼 |
감쇠력 조정식 완충기
|
|
GB0809069D0
(en)
|
2008-05-19 |
2008-06-25 |
Univ Leuven Kath |
Gene signatures
|
|
JP2011516520A
(ja)
|
2008-04-07 |
2011-05-26 |
アブリンクス エン.ヴェー. |
Notch経路に指向性を有するアミノ酸配列及びその使用
|
|
WO2009127691A1
(en)
|
2008-04-17 |
2009-10-22 |
Ablynx N.V. |
Peptides capable of binding to serum proteins and compounds, constructs and polypeptides comprising the same
|
|
EP2285833B1
(de)
|
2008-05-16 |
2014-12-17 |
Ablynx N.V. |
Gegen cxcr4 und andere gpcr gerichtete aminosäuresequenzen sowie verbindungen damit
|
|
WO2009142773A2
(en)
|
2008-05-22 |
2009-11-26 |
Bristol-Myers Squibb Company |
Multivalent fibronectin based scaffold domain proteins
|
|
US20100075329A1
(en)
|
2008-09-23 |
2010-03-25 |
O'toole Margot |
Methods for predicting production of activating signals by cross-linked binding proteins
|
|
GB0900425D0
(en)
|
2009-01-12 |
2009-02-11 |
Ucb Pharma Sa |
Biological products
|
|
WO2010091182A2
(en)
|
2009-02-04 |
2010-08-12 |
Molecular Innovations |
Methods for screening candidate agents for modulating prorenin and renin, assays for detecting prorenin, and antibodies used therein
|
|
US10005830B2
(en)
|
2009-03-05 |
2018-06-26 |
Ablynx N.V. |
Antigen binding dimer-complexes, methods of making/avoiding and uses thereof
|
|
AU2010243551B2
(en)
|
2009-04-30 |
2015-03-26 |
Ablynx Nv |
Method for the production of domain antibodies
|
|
US9290577B2
(en)
|
2009-07-03 |
2016-03-22 |
Avipep Pty Limited |
Immuno-conjugates and methods for producing them
|
|
DK3622815T3
(da)
|
2009-07-08 |
2023-06-26 |
Kymab Ltd |
Gnavermodeller og terapeutiske molekyler
|
|
WO2011003622A1
(en)
|
2009-07-10 |
2011-01-13 |
Ablynx N.V. |
Method for the production of variable domains
|
|
EP2459053A2
(de)
|
2009-07-28 |
2012-06-06 |
F. Hoffmann-La Roche AG |
Nicht invasives optisches in-vivo-bildgebungsverfahren
|
|
WO2011027132A1
(en)
|
2009-09-03 |
2011-03-10 |
Cancer Research Technology Limited |
Clec14a inhibitors
|
|
LT2805731T
(lt)
|
2009-09-03 |
2019-02-11 |
Ablynx N.V. |
Stabilios polipeptidų kompozicijos ir jų panaudojimas
|
|
CN102781963B
(zh)
|
2009-10-27 |
2018-02-16 |
Ucb医药有限公司 |
功能修饰性NAv1.7抗体
|
|
GB0922434D0
(en)
|
2009-12-22 |
2010-02-03 |
Ucb Pharma Sa |
antibodies and fragments thereof
|
|
GB0922435D0
(en)
|
2009-12-22 |
2010-02-03 |
Ucb Pharma Sa |
Method
|
|
US9234037B2
(en)
|
2009-10-27 |
2016-01-12 |
Ucb Biopharma Sprl |
Method to generate antibodies to ion channels
|
|
JP2013514788A
(ja)
|
2009-12-23 |
2013-05-02 |
アビペップ ピーティーワイ リミテッド |
イムノコンジュゲート及びその作製方法2
|
|
WO2011083140A1
(en)
|
2010-01-08 |
2011-07-14 |
Ablynx Nv |
Immunoglobulin single variable domain directed against human cxcr4
|
|
EP2531523A1
(de)
|
2010-02-05 |
2012-12-12 |
Ablynx N.V. |
An serumalbumin bindende peptide und verbindungen, konstrukte und polypeptide damit
|
|
DK2533761T3
(da)
|
2010-02-11 |
2019-06-24 |
Ablynx Nv |
Fremgangsmåder og sammensætninger til fremstilling af aerosoler
|
|
EP2553449A2
(de)
|
2010-03-26 |
2013-02-06 |
Westfälische Wilhelms-Universität Münster |
Ersatztherapie für glucocorticoide
|
|
US9101674B2
(en)
|
2010-03-29 |
2015-08-11 |
Vib Vzw |
Targeting and in vivo imaging of tumor-associated macrophages
|
|
US9556273B2
(en)
|
2010-03-29 |
2017-01-31 |
Vib Vzw |
Anti-macrophage mannose receptor single variable domains for targeting and in vivo imaging of tumor-associated macrophages
|
|
GB201105584D0
(en)
|
2011-04-01 |
2011-05-18 |
Imp Innovations Ltd |
Cancer methods
|
|
CN102939538A
(zh)
|
2010-05-07 |
2013-02-20 |
霍夫曼-拉罗奇有限公司 |
用于离体检测细胞的诊断方法
|
|
WO2011161263A1
(en)
|
2010-06-25 |
2011-12-29 |
Ablynx Nv |
Pharmaceutical compositions for cutaneous administration
|
|
AU2011273360A1
(en)
|
2010-07-02 |
2013-02-07 |
Vib Vzw |
The role of Fragile X mental retardation gene and protein in cancer metastasis
|
|
GB201012845D0
(en)
|
2010-07-30 |
2010-09-15 |
Vib Vzw |
Inhibition of dicer function for treatment of cancer
|
|
US20120244141A1
(en)
|
2010-09-28 |
2012-09-27 |
Boehringer Ingelheim International Gmbh |
Stratification of cancer patients for susceptibility to therapy with PTK2 inhibitors
|
|
PL3279214T3
(pl)
|
2010-10-29 |
2025-03-24 |
Ablynx Nv |
Sposób wytwarzania pojedynczych domen zmiennych immunoglobuliny
|
|
GB201018602D0
(en)
|
2010-11-04 |
2010-12-22 |
Vib Vzw |
MMP8 inactivating antigen binding proteins
|
|
EP2683413A1
(de)
|
2011-03-07 |
2014-01-15 |
F.Hoffmann-La Roche Ag |
In-vivo-auswahl therapeutisch aktiver antikörper
|
|
US20140099264A1
(en)
|
2011-03-07 |
2014-04-10 |
F. Hoffman-La Roche Ag |
Means and methods for in vivo testing of therapeutic antibodies
|
|
US9624294B2
(en)
|
2011-03-14 |
2017-04-18 |
Cellmid Limited |
Antibody recognizing N-domain of midkine
|
|
AU2012234282B2
(en)
|
2011-03-28 |
2015-07-16 |
Ablynx Nv |
Method for producing solid formulations comprising immunoglobulin single variable domains
|
|
WO2012152823A1
(en)
|
2011-05-09 |
2012-11-15 |
Ablynx Nv |
Method for the production of immunoglobulin single variable domains
|
|
WO2012163887A1
(en)
|
2011-05-27 |
2012-12-06 |
Ablynx Nv |
Inhibition of bone resorption with rankl binding peptides
|
|
WO2012166906A1
(en)
|
2011-05-31 |
2012-12-06 |
Massachusetts Institute Of Technology |
Cell-directed synthesis of multifunctional nanopatterns and nanomaterials
|
|
EP2718326B1
(de)
|
2011-06-13 |
2020-08-19 |
CSL Limited |
Antikörper gegen g-csfr und verwendungen davon
|
|
EP2723772A1
(de)
|
2011-06-23 |
2014-04-30 |
Ablynx N.V. |
Gegen ige gerichtete variable immunglobulin-einzeldomänen
|
|
GB201112056D0
(en)
|
2011-07-14 |
2011-08-31 |
Univ Leuven Kath |
Antibodies
|
|
GB201115529D0
(en)
|
2011-09-08 |
2011-10-26 |
Imp Innovations Ltd |
Antibodies, uses and methods
|
|
BR112014006394A2
(pt)
|
2011-09-19 |
2017-03-28 |
Kymab Ltd |
manipulação de diversidade genética de imunoglobulina e terapêuticos multi-anticorpos
|
|
WO2013041722A1
(en)
|
2011-09-23 |
2013-03-28 |
Ablynx Nv |
Prolonged inhibition of interleukin-6 mediated signaling
|
|
AU2012327878A1
(en)
|
2011-10-28 |
2014-05-29 |
Patrys Limited |
PAT-LM1 epitopes and methods for using same
|
|
US9253965B2
(en)
|
2012-03-28 |
2016-02-09 |
Kymab Limited |
Animal models and therapeutic molecules
|
|
EP2785741A1
(de)
|
2011-12-02 |
2014-10-08 |
Cancer Research Technology Limited |
Antikörper gegen hgf-rezeptor und verwendungen
|
|
WO2013113696A1
(en)
|
2012-01-30 |
2013-08-08 |
Vib Vzw |
Means and method for diagnosis and treatment of alzheimer's disease
|
|
WO2013121042A1
(en)
|
2012-02-16 |
2013-08-22 |
Vib Vzw |
PP2A SUBUNITS IN DNA REPAIR, THE PP2A B55α SUBUNIT AS NOVEL PHD2 INTERACTING PROTEIN, AND IMPLICATIONS FOR CANCER
|
|
GB2502127A
(en)
|
2012-05-17 |
2013-11-20 |
Kymab Ltd |
Multivalent antibodies and in vivo methods for their production
|
|
US10251377B2
(en)
|
2012-03-28 |
2019-04-09 |
Kymab Limited |
Transgenic non-human vertebrate for the expression of class-switched, fully human, antibodies
|
|
JP6411333B2
(ja)
|
2012-05-24 |
2018-10-24 |
ブイアイビー ブイゼットダブリュVib Vzw |
腫瘍関連マクロファージのターゲティングおよびinvivoイメージング用抗マクロファージマンノース受容体単一可変ドメイン
|
|
US11339208B1
(en)
|
2012-05-31 |
2022-05-24 |
United States Of America As Represented By The Secretary Of The Air Force |
Camelidae single-domain antibodies against Yersinia pestis and methods of use
|
|
EP2867674B1
(de)
|
2012-06-28 |
2018-10-10 |
UCB Biopharma SPRL |
Verfahren zur identifikation von verbindungen von therapeutischem interesse
|
|
WO2014087010A1
(en)
|
2012-12-07 |
2014-06-12 |
Ablynx N.V. |
IMPROVED POLYPEPTIDES DIRECTED AGAINST IgE
|
|
CN105102478A
(zh)
|
2013-01-30 |
2015-11-25 |
弗拉芒区生物技术研究所 |
用于筛选和药物发现目的的新型嵌合多肽
|
|
US20150368339A1
(en)
|
2013-02-05 |
2015-12-24 |
Vib Vzw |
Muscarinic acetylcholine receptor binding agents and uses thereof
|
|
CN117843785A
(zh)
|
2013-02-07 |
2024-04-09 |
Csl有限公司 |
Il-11r结合蛋白及其应用
|
|
JP6499090B2
(ja)
|
2013-03-15 |
2019-04-10 |
ブイアイビー ブイゼットダブリュVib Vzw |
心血管疾患において使用するための抗マクロファージマンノース受容体単一可変ドメイン
|
|
WO2014144292A2
(en)
|
2013-03-15 |
2014-09-18 |
Sanofi Pasteur Biologics , Llc |
Antibodies against clostridium difficile toxins and methods of using the same
|
|
US9788534B2
(en)
|
2013-03-18 |
2017-10-17 |
Kymab Limited |
Animal models and therapeutic molecules
|
|
EP2992101B1
(de)
|
2013-04-29 |
2018-10-10 |
Agrosavfe N.V. |
Agrochemische zusammensetzungen mit an sphingolipide bindenden antikörpern
|
|
US11707056B2
(en)
|
2013-05-02 |
2023-07-25 |
Kymab Limited |
Animals, repertoires and methods
|
|
US9783593B2
(en)
|
2013-05-02 |
2017-10-10 |
Kymab Limited |
Antibodies, variable domains and chains tailored for human use
|
|
NL1040254C2
(en)
|
2013-05-17 |
2014-11-24 |
Ablynx Nv |
Stable formulations of immunoglobulin single variable domains and uses thereof.
|
|
AU2014330922A1
(en)
|
2013-10-01 |
2016-03-03 |
Kymab Limited |
Animal models and therapeutic molecules
|
|
RU2718054C2
(ru)
|
2013-11-28 |
2020-03-30 |
СиЭсЭл ЛИМИТЕД |
Способ лечения нефропатии
|
|
EP2883883A1
(de)
|
2013-12-16 |
2015-06-17 |
Cardio3 Biosciences S.A. |
Therapeutische Ziele und Mittel zur Behandlung von ischämiebedingten Reperfusionsschäden
|
|
US8986694B1
(en)
|
2014-07-15 |
2015-03-24 |
Kymab Limited |
Targeting human nav1.7 variants for treatment of pain
|
|
US9067998B1
(en)
|
2014-07-15 |
2015-06-30 |
Kymab Limited |
Targeting PD-1 variants for treatment of cancer
|
|
US9914769B2
(en)
|
2014-07-15 |
2018-03-13 |
Kymab Limited |
Precision medicine for cholesterol treatment
|
|
US9045545B1
(en)
|
2014-07-15 |
2015-06-02 |
Kymab Limited |
Precision medicine by targeting PD-L1 variants for treatment of cancer
|
|
US8992927B1
(en)
|
2014-07-15 |
2015-03-31 |
Kymab Limited |
Targeting human NAV1.7 variants for treatment of pain
|
|
WO2015089585A1
(en)
|
2013-12-18 |
2015-06-25 |
Csl Limited |
Method of treating wounds
|
|
US10233241B2
(en)
|
2014-01-30 |
2019-03-19 |
Vib Vzw |
Opioid receptor binding agents and uses thereof
|
|
GB201403775D0
(en)
|
2014-03-04 |
2014-04-16 |
Kymab Ltd |
Antibodies, uses & methods
|
|
NL2013661B1
(en)
|
2014-10-21 |
2016-10-05 |
Ablynx Nv |
KV1.3 Binding immunoglobulins.
|
|
US9139648B1
(en)
|
2014-07-15 |
2015-09-22 |
Kymab Limited |
Precision medicine by targeting human NAV1.9 variants for treatment of pain
|
|
DK3194976T3
(da)
|
2014-07-22 |
2020-07-13 |
Vib Vzw |
Fremgangsmåder til udvælgelse af midler, som stabiliserer proteinkomplekser
|
|
WO2016016329A1
(en)
|
2014-07-29 |
2016-02-04 |
Vrije Universiteit Brussel |
Radio-labelled antibody fragments for use in the prognosis, diagnosis of cancer as well as for the prediction of cancer therapy response
|
|
EP3718574A1
(de)
|
2014-07-29 |
2020-10-07 |
Vrije Universiteit Brussel |
Radioaktiv markierte antikörperfragmente zur verwendung bei der vorbeugung und/oder behandlung von krebs
|
|
AU2015336946A1
(en)
|
2014-10-23 |
2017-04-13 |
La Trobe University |
Fn14-binding proteins and uses thereof
|
|
US10858666B2
(en)
|
2014-11-05 |
2020-12-08 |
Biotalys |
Transgenic plants expressing a variable domain of a heavy chain antibody (VHH) that binds to a sphingolipid of a fungus
|
|
WO2016094962A1
(en)
|
2014-12-19 |
2016-06-23 |
Monash University |
Il-21 antibodies
|
|
AU2015366284B2
(en)
|
2014-12-19 |
2021-07-22 |
Ablynx N.V. |
Cysteine linked nanobody dimers
|
|
GB201501004D0
(en)
|
2015-01-21 |
2015-03-04 |
Cancer Rec Tech Ltd |
Inhibitors
|
|
MX390949B
(es)
|
2015-07-17 |
2025-03-21 |
Univ Brussel Vrije |
Fragmentos de anticuerpos radiomarcados para uso en tratamiento de cancer.
|
|
WO2018028647A1
(en)
|
2016-08-10 |
2018-02-15 |
Legend Biotech Usa Inc. |
Chimeric antigen receptors targeting bcma and methods of use thereof
|
|
CN105384825B
(zh)
|
2015-08-11 |
2018-06-01 |
南京传奇生物科技有限公司 |
一种基于单域抗体的双特异性嵌合抗原受体及其应用
|
|
GB201518675D0
(en)
|
2015-10-21 |
2015-12-02 |
Cellcap Technologies Ltd |
Detection of structural forms of proteins
|
|
KR20180080337A
(ko)
|
2015-11-27 |
2018-07-11 |
아블린쓰 엔.브이. |
Cd40l을 억제하는 폴리펩티드
|
|
AU2016361462B2
(en)
|
2015-11-27 |
2023-09-21 |
Csl Limited |
CD131 binding proteins and uses thereof
|
|
WO2017097889A1
(en)
|
2015-12-10 |
2017-06-15 |
Katholieke Universiteit Leuven |
Anti adamts13 antibodies and their use for treatment or prevention of haemorrhagic disorders due to ventricular assist device
|
|
US11243214B2
(en)
|
2016-04-22 |
2022-02-08 |
Université Libre de Bruxelles |
Biomarker expressed in pancreatic beta cells useful in imaging or targeting beta cells
|
|
WO2017182605A1
(en)
|
2016-04-22 |
2017-10-26 |
Université Libre de Bruxelles |
A new biomarker expressed in pancreatic beta cells useful in imaging or targeting beta cells
|
|
CN109311968A
(zh)
|
2016-05-02 |
2019-02-05 |
埃博灵克斯股份有限公司 |
治疗rsv感染
|
|
RU2769282C2
(ru)
|
2016-06-20 |
2022-03-30 |
Кимаб Лимитед |
Анти-PD-L1 и IL-2 цитокины
|
|
WO2018007442A1
(en)
|
2016-07-06 |
2018-01-11 |
Ablynx N.V. |
Treatment of il-6r related diseases
|
|
WO2018014260A1
(en)
|
2016-07-20 |
2018-01-25 |
Nanjing Legend Biotech Co., Ltd. |
Multispecific antigen binding proteins and methods of use thereof
|
|
WO2018029182A1
(en)
|
2016-08-08 |
2018-02-15 |
Ablynx N.V. |
Il-6r single variable domain antibodies for treatment of il-6r related diseases
|
|
US11098113B2
(en)
|
2016-09-15 |
2021-08-24 |
Vib Vzw |
Immunoglobulin single variable domains directed against macrophage migration inhibitory factor
|
|
US20190248920A1
(en)
|
2016-09-23 |
2019-08-15 |
Csl Limited |
Coagulation factor binding proteins and uses thereof
|
|
WO2018068201A1
(en)
|
2016-10-11 |
2018-04-19 |
Nanjing Legend Biotech Co., Ltd. |
Single-domain antibodies and variants thereof against ctla-4
|
|
EP3534947A1
(de)
|
2016-11-03 |
2019-09-11 |
Kymab Limited |
Antikörper, kombinationen mit antikörpern, biomarker, verwendungen und verfahren
|
|
BR112019010061A2
(pt)
|
2016-11-16 |
2019-08-13 |
Ablynx Nv |
polipeptídeos de recrutamento de células t capazes de se ligarem ao cd123 e tcr alfa/beta
|
|
WO2018099968A1
(en)
|
2016-11-29 |
2018-06-07 |
Ablynx N.V. |
Treatment of infection by respiratory syncytial virus (rsv)
|
|
JP7186401B2
(ja)
|
2017-02-28 |
2022-12-09 |
フエー・イー・ベー・フエー・ゼツト・ウエー |
タンパク質の経口送達のための手段及び方法
|
|
US20200033347A1
(en)
|
2017-04-18 |
2020-01-30 |
Universite Libre De Bruxelles |
Biomarkers And Targets For Proliferative Diseases
|
|
KR20200005635A
(ko)
|
2017-05-11 |
2020-01-15 |
브이아이비 브이지더블유 |
가변 면역글로불린 도메인의 글리코실화
|
|
JP7249961B2
(ja)
|
2017-06-02 |
2023-03-31 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Adamts5、mmp13およびアグリカンに結合するポリペプチド
|
|
CN118894939A
(zh)
|
2017-06-02 |
2024-11-05 |
默克专利股份有限公司 |
结合adamts的免疫球蛋白
|
|
NZ759601A
(en)
|
2017-06-02 |
2023-06-30 |
Merck Patent Gmbh |
Aggrecan binding immunoglobulins
|
|
TW202417517A
(zh)
|
2017-06-02 |
2024-05-01 |
德商麥克專利有限公司 |
與mmp13結合之免疫球蛋白
|
|
GB201709379D0
(en)
|
2017-06-13 |
2017-07-26 |
Univ Leuven Kath |
Humanised ADAMTS13 binding antibodies
|
|
WO2019000223A1
(en)
|
2017-06-27 |
2019-01-03 |
Nanjing Legend Biotech Co., Ltd. |
ENABLERS OF IMMUNE EFFECTOR CELLS OF CHIMERIC ANTIBODIES AND METHODS OF USE THEREOF
|
|
KR102806328B1
(ko)
|
2017-07-11 |
2025-05-14 |
알렉시온 파마슈티칼스, 인코포레이티드 |
보체 성분 c5 또는 혈청 알부민에 결합하는 폴리펩티드 및 그의 융합 단백질
|
|
CA3070253A1
(en)
|
2017-07-19 |
2019-01-24 |
Vib Vzw |
Serum albumin binding agents
|
|
WO2019016784A1
(en)
|
2017-07-21 |
2019-01-24 |
Universidade De Coimbra |
ANTI-NUCLEOLIN ANTIBODIES
|
|
EP4512469A3
(de)
|
2017-09-11 |
2025-05-21 |
Monash University |
Bindung von proteinen an den menschlichen thrombinrezeptor par4
|
|
WO2019067015A1
(en)
|
2017-09-29 |
2019-04-04 |
City Of Hope |
RECEPTORS OF CHIMERIC ANTIGENS AND BISPECIFIC ANTIBODIES FOR THE TREATMENT OF COAT CELL LYMPHOMA
|
|
JP7793287B2
(ja)
|
2017-10-18 |
2026-01-05 |
シーエスエル リミティド |
ヒト血清アルブミン変異体およびその使用
|
|
KR20200091400A
(ko)
*
|
2017-10-31 |
2020-07-30 |
브이아이비 브이지더블유 |
신규한 항원-결합 키메라 단백질 및 이의 방법 및 용도
|
|
US10017560B1
(en)
|
2017-11-16 |
2018-07-10 |
King Saud University |
Nanobody against begomoviruses
|
|
US20210179721A1
(en)
|
2017-11-29 |
2021-06-17 |
Csl Limited |
Method of treating or preventing ischemia-reperfusion injury
|
|
JP7807196B2
(ja)
|
2017-12-05 |
2026-01-27 |
セリアド オンコロジー エス.アー. |
Nkg2dベースの受容体を発現する免疫細胞のフラトリサイドの減少
|
|
CN112236514A
(zh)
|
2017-12-05 |
2021-01-15 |
塞利亚德股份公司 |
改善细胞过继转移的持久性的组合物和方法
|
|
CN117050184A
(zh)
|
2017-12-28 |
2023-11-14 |
南京传奇生物科技有限公司 |
针对tigit的单域抗体和其变体
|
|
CN111699200B
(zh)
|
2018-01-15 |
2023-05-26 |
南京传奇生物科技有限公司 |
针对pd-1的单域抗体和其变体
|
|
WO2019155041A1
(en)
|
2018-02-12 |
2019-08-15 |
Vib Vzw |
Gβγ COMPLEX ANTIBODIES AND USES THEREOF
|
|
CA3092421A1
(en)
|
2018-03-01 |
2019-09-06 |
Vrije Universiteit Brussel |
Human pd-l1-binding immunoglobulins
|
|
IL277307B2
(en)
|
2018-03-23 |
2025-03-01 |
Univ Bruxelles |
Wnt signaling agonist molecules
|
|
US12281160B2
(en)
|
2018-03-23 |
2025-04-22 |
Csl Limited |
Method of treating asthma
|
|
CA3095080A1
(en)
|
2018-03-27 |
2019-10-03 |
Coen MAAS |
Targeted thrombolysis for treatment of microvascular thrombosis
|
|
TW202003567A
(zh)
|
2018-03-30 |
2020-01-16 |
大陸商南京傳奇生物科技有限公司 |
針對lag-3之單一結構域抗體及其用途
|
|
US20210221864A1
(en)
|
2018-08-24 |
2021-07-22 |
City Of Hope |
Masked cytokine conjugates
|
|
GB201814451D0
(en)
|
2018-09-05 |
2018-10-17 |
Valerie Nicholas Carl Kristoffer |
Methods
|
|
WO2020221769A1
(en)
|
2019-04-29 |
2020-11-05 |
Confo Therapeutics N.V. |
Screening methods and assays for use with transmembrane proteins, in particular with gpcrs
|
|
EP3962599A1
(de)
|
2019-04-30 |
2022-03-09 |
Vib Vzw |
Stabilisierungsmittel des transmembrankonduktanzregulators bei zystischer fibrose
|
|
EP3976067A1
(de)
|
2019-05-28 |
2022-04-06 |
Vib Vzw |
Cd8+-t-zellen ohne plexine und ihre anwendung zur krebsbehandlung
|
|
WO2020239945A1
(en)
|
2019-05-28 |
2020-12-03 |
Vib Vzw |
Cancer treatment by targeting plexins in the immune compartment
|
|
GB2584441A
(en)
|
2019-06-03 |
2020-12-09 |
Fenomark Diagnostics Ab |
Medical uses, methods and uses
|
|
JP7171737B2
(ja)
*
|
2019-07-23 |
2022-11-15 |
源道隆(蘇州)医学科技有限公司 |
Sftsvに結合可能なナノ抗体及びその使用
|
|
WO2021078786A1
(en)
|
2019-10-21 |
2021-04-29 |
Vib Vzw |
Nanodisc-specific antigen-binding chimeric proteins
|
|
EP4051714A4
(de)
|
2019-10-28 |
2023-11-22 |
Monash University |
Antikörper zum binden von plasmin
|
|
CA3160506A1
(en)
|
2019-11-11 |
2021-05-20 |
Ibi-Ag Innovative Bio Insecticides Ltd. |
Insect control nanobodies and uses thereof
|
|
US20220411495A1
(en)
|
2019-11-27 |
2022-12-29 |
Vib Vzw |
Positive allosteric modulators of the calcium-sensing receptor
|
|
GB201918279D0
(en)
|
2019-12-12 |
2020-01-29 |
Vib Vzw |
Glycosylated single chain immunoglobulin domains
|
|
WO2021119761A1
(en)
|
2019-12-20 |
2021-06-24 |
Hudson Institute of Medical Research |
Cxcl10 binding proteins and uses thereof
|
|
US20240027467A1
(en)
|
2019-12-20 |
2024-01-25 |
Vib Vzw |
Nanobody Exchange Chromatography
|
|
WO2021140205A1
(en)
|
2020-01-10 |
2021-07-15 |
Confo Therapeutics N.V. |
Methods for generating antibodies and antibody fragments and libraries comprising same
|
|
WO2021156490A2
(en)
|
2020-02-06 |
2021-08-12 |
Vib Vzw |
Corona virus binders
|
|
KR20230012464A
(ko)
|
2020-02-25 |
2023-01-26 |
브이아이비 브이지더블유 |
류신-풍부 반복 키나제 2 알로스테릭 조절제
|
|
WO2021198396A1
(en)
|
2020-03-31 |
2021-10-07 |
Biotalys NV |
Anti-fungal polypeptides
|
|
CN113527488B
(zh)
|
2020-04-22 |
2026-04-17 |
迈威(上海)生物科技股份有限公司 |
一种靶向人程序性死亡配体1(pd-l1)的单可变域抗体及其衍生物
|
|
WO2021229104A1
(en)
|
2020-05-15 |
2021-11-18 |
Université de Liège |
Anti-cd38 single-domain antibodies in disease monitoring and treatment
|
|
US12583929B2
(en)
|
2020-06-04 |
2026-03-24 |
CSL Innovation Pty Ltd |
Method of treating acute respiratory distress syndrome
|
|
WO2022003156A1
(en)
|
2020-07-02 |
2022-01-06 |
Oncurious Nv |
Ccr8 non-blocking binders
|
|
JP7846667B2
(ja)
|
2020-07-16 |
2026-04-15 |
レジェンド バイオテック アイルランド リミテッド |
Cd20結合分子及びその使用
|
|
WO2022023584A1
(en)
|
2020-07-31 |
2022-02-03 |
Biotalys NV |
Methods of increasing recombinant protein yields
|
|
US20230303654A1
(en)
|
2020-08-11 |
2023-09-28 |
City Of Hope |
Compositions and uses of sars-cov-2 targeted chimeric antigen receptor modified nk cells
|
|
WO2022063947A1
(en)
|
2020-09-24 |
2022-03-31 |
Vib Vzw |
Combination of p2y6 inhibitors and immune checkpoint inhibitors
|
|
WO2022063957A1
(en)
|
2020-09-24 |
2022-03-31 |
Vib Vzw |
Biomarker for anti-tumor therapy
|
|
AU2021350156A1
(en)
|
2020-09-25 |
2023-06-08 |
Ablynx Nv |
Polypeptides comprising immunoglobulin single variable domains targeting il-13 and ox40l
|
|
JP2024508207A
(ja)
|
2020-12-02 |
2024-02-26 |
ブイアイビー ブイゼットダブリュ |
がんに対する組み合わせ治療におけるltbrアゴニスト
|
|
WO2022117569A1
(en)
|
2020-12-02 |
2022-06-09 |
Oncurious Nv |
A ccr8 antagonist antibody in combination with a lymphotoxin beta receptor agonist antibody in therapy against cancer
|
|
EP4263602A1
(de)
|
2020-12-18 |
2023-10-25 |
Ablynx N.V. |
Polypeptide mit variablen immunglobulin-einzeldomänen zum targeting von il-6 und tnf-alpha
|
|
GB202020502D0
(en)
|
2020-12-23 |
2021-02-03 |
Vib Vzw |
Antibody composistion for treatment of corona virus infection
|
|
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(de)
|
2020-12-24 |
2023-11-01 |
Vib Vzw |
Kreuzreaktive menschliche ccr8-bindemittel aus der maus
|
|
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(en)
|
2020-12-24 |
2022-06-30 |
Vib Vzw |
Non-blocking human ccr8 binders
|
|
WO2022136647A1
(en)
|
2020-12-24 |
2022-06-30 |
Oncurious Nv |
Human ccr8 binders
|
|
GB2603166A
(en)
|
2021-01-29 |
2022-08-03 |
Thelper As |
Therapeutic and Diagnostic Agents and Uses Thereof
|
|
CN117794566A
(zh)
|
2021-02-05 |
2024-03-29 |
Vib研究所 |
沙贝病毒结合剂
|
|
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(en)
|
2021-02-05 |
2023-10-01 |
Vib Vzw [Be/Be |
Sarbevirus binders
|
|
WO2022175392A1
(en)
|
2021-02-17 |
2022-08-25 |
Vib Vzw |
Inhibition of slc4a4 in the treatment of cancer
|
|
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(de)
|
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2023-12-27 |
Vib Vzw |
Kationunabhängige mannose-6-phosphatrezeptorbindemittel
|
|
WO2022199804A1
(en)
|
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2022-09-29 |
Vib Vzw |
Nek6 inhibition to treat als and ftd
|
|
US20240261446A1
(en)
|
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2024-08-08 |
Université de Liège |
Anti-cd38 single domain antibodies in disease monitoring and treatment
|
|
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(en)
|
2021-06-23 |
2022-12-29 |
Vib Vzw |
Means and methods for selection of specific binders
|
|
WO2023274183A1
(zh)
|
2021-06-29 |
2023-01-05 |
江苏先声药业有限公司 |
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|
|
US20240343803A1
(en)
|
2021-07-30 |
2024-10-17 |
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Anti-Pvrig/Anti-Tigit Bispecific Antibodies And Applications Thereof
|
|
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(de)
|
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2024-06-05 |
Vib Vzw |
Kationunabhängige mannose-6-phosphat-rezeptorbindemittel für gezielten proteinabbau
|
|
WO2023023220A1
(en)
|
2021-08-20 |
2023-02-23 |
Alexion Pharmaceuticals, Inc. |
Methods for treating sickle cell disease or beta thalassemia using a complement alternative pathway inhibitor
|
|
WO2023023227A1
(en)
|
2021-08-20 |
2023-02-23 |
Alexion Pharmaceuticals, Inc. |
Methods for treating sickle cell disease or beta thalassemia using complement alternative pathway inhibitors
|
|
WO2023057601A1
(en)
|
2021-10-06 |
2023-04-13 |
Biotalys NV |
Anti-fungal polypeptides
|
|
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(en)
|
2021-11-05 |
2023-05-11 |
Katholieke Universiteit Leuven |
Neutralizing anti-sars-cov-2 human antibodies
|
|
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(de)
|
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2023-05-10 |
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Neutralisierende humane anti-sars-cov-2-antikörper
|
|
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(zh)
|
2021-12-03 |
2023-06-08 |
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|
|
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(ko)
|
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2024-08-13 |
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|
|
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(zh)
|
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2023-07-06 |
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|
|
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(en)
|
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2023-07-20 |
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|
|
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(en)
|
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Therapeutic and diagnostic agents and uses thereof
|
|
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(de)
|
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Verfahren zur genomeditierung
|
|
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(de)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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2023-11-23 |
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|
|
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(en)
|
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|
|
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(ja)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(zh)
|
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|
|
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|
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|
|
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(de)
|
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|
|
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(en)
|
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|
|
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|
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Biotalys NV |
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Biotalys NV |
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