ATE374944T1 - Identifizierung hochaffiner moleküle durch screening mit begrenzter verdünnung - Google Patents

Identifizierung hochaffiner moleküle durch screening mit begrenzter verdünnung

Info

Publication number
ATE374944T1
ATE374944T1 AT02792319T AT02792319T ATE374944T1 AT E374944 T1 ATE374944 T1 AT E374944T1 AT 02792319 T AT02792319 T AT 02792319T AT 02792319 T AT02792319 T AT 02792319T AT E374944 T1 ATE374944 T1 AT E374944T1
Authority
AT
Austria
Prior art keywords
antigen
identification
antibodies
limited dilution
molecules
Prior art date
Application number
AT02792319T
Other languages
English (en)
Inventor
John Babcook
Jaspal Kang
Xiao-Chi Jia
Li Zhang
Original Assignee
Abgenix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23319750&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE374944(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abgenix Inc filed Critical Abgenix Inc
Application granted granted Critical
Publication of ATE374944T1 publication Critical patent/ATE374944T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • G01N33/6857Antibody fragments

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Carbon And Carbon Compounds (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
AT02792319T 2001-12-03 2002-12-02 Identifizierung hochaffiner moleküle durch screening mit begrenzter verdünnung ATE374944T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33725001P 2001-12-03 2001-12-03

Publications (1)

Publication Number Publication Date
ATE374944T1 true ATE374944T1 (de) 2007-10-15

Family

ID=23319750

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02792319T ATE374944T1 (de) 2001-12-03 2002-12-02 Identifizierung hochaffiner moleküle durch screening mit begrenzter verdünnung

Country Status (8)

Country Link
US (1) US7754433B2 (de)
EP (1) EP1554576B9 (de)
AT (1) ATE374944T1 (de)
AU (1) AU2002357779A1 (de)
CA (1) CA2478547C (de)
DE (1) DE60222816T2 (de)
ES (1) ES2294193T3 (de)
WO (1) WO2003048730A2 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60222816T2 (de) 2001-12-03 2008-07-03 Amgen Fremont Inc. Identifizierung hochaffiner moleküle durch screening mit begrenzter verdünnung
US7285269B2 (en) 2002-12-02 2007-10-23 Amgen Fremont, Inc. Antibodies directed to tumor necrosis factor
KR20130065723A (ko) 2003-06-27 2013-06-19 암젠 프레몬트 인코포레이티드 상피 성장 인자 수용체의 결실 돌연변이체 지향 항체 및 그 용도
CN101048426A (zh) * 2004-10-22 2007-10-03 金克克国际有限公司 分离人抗体
EP1824886B1 (de) 2004-11-17 2010-12-22 Amgen Inc. Vollständige humane monoklonale antikörper gegen il-13
MX2007013058A (es) 2005-04-20 2008-02-22 Amgen Fremont Inc Anticuerpos monoclonales de alta afinidad completamente humanos para interleucina-8 y epitopes para dichos anticuerpos.
AR056857A1 (es) 2005-12-30 2007-10-24 U3 Pharma Ag Anticuerpos dirigidos hacia her-3 (receptor del factor de crecimiento epidérmico humano-3) y sus usos
US20070207141A1 (en) 2006-02-28 2007-09-06 Ivan Lieberburg Methods of treating inflammatory and autoimmune diseases with natalizumab
MX2008011176A (es) 2006-03-03 2008-09-10 Elan Pharm Inc Metodos para tratar padecimientos inflamatorios y autoinmunes con natalizumab.
KR101790802B1 (ko) 2009-09-03 2017-10-27 머크 샤프 앤드 돔 코포레이션 항-gitr 항체
EP2896632B1 (de) 2009-11-13 2017-10-25 Daiichi Sankyo Europe GmbH Material und Verfahren zur Behandlung oder Vorbeugung von HER-3-assoziierten Erkrankungen
US11287423B2 (en) 2010-01-11 2022-03-29 Biogen Ma Inc. Assay for JC virus antibodies
DK2715352T3 (da) * 2011-05-31 2019-05-20 Biogen Ma Inc Fremgangsmåde til vurdering af risiko for pml
PE20141937A1 (es) 2011-11-16 2014-12-18 Amgen Inc Metodos para tratar trastornos relacionados con mutante viii de eliminacion de factor de crecimiento epidermico
US9441039B2 (en) 2012-05-07 2016-09-13 Amgen Inc. Anti-erythropoietin antibodies
WO2014193804A1 (en) 2013-05-28 2014-12-04 Biogen Idec Ma Inc. Method of assessing risk of pml
US10422806B1 (en) * 2013-07-25 2019-09-24 Theranos Ip Company, Llc Methods for improving assays of biological samples
EP3112869A1 (de) * 2015-06-30 2017-01-04 IMEC vzw Sensorvorrichtung
CA3042236A1 (en) 2016-10-28 2018-05-03 Washington University Anti-apoe antibodies
AU2020323901A1 (en) 2019-07-26 2022-02-24 Amgen Inc. Anti-IL13 antigen binding proteins
CN114814202A (zh) * 2022-03-25 2022-07-29 浙江工业大学 一种基于96孔板固载分子马达的传感器检测试剂盒、及其用于p24抗原体外检测的方法

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US5426029A (en) * 1986-03-31 1995-06-20 T Cell Diagnostics, Inc. Therapeutic and diagnostic methods using leukocyte surface antigens
US5300425A (en) * 1987-10-13 1994-04-05 Terrapin Technologies, Inc. Method to produce immunodiagnostic reagents
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NO164622C (no) 1988-05-11 1990-10-24 Tore Lindmo Binaer immunometrisk partikkelbasert metode for maaling av spesifikke serum-antigener ved hjelp av vaeskestroemsmikrofotometri og et ferdigpreparert maaloppsett derav.
US5434076A (en) * 1989-12-18 1995-07-18 Board Of Regents, The University Of Texas System Tumor-specific, cell surface-binding monoclonal antibodies
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DE60222816T2 (de) 2001-12-03 2008-07-03 Amgen Fremont Inc. Identifizierung hochaffiner moleküle durch screening mit begrenzter verdünnung
CA2469196A1 (en) * 2001-12-03 2003-06-12 Abgenix, Inc. Discovery of therapeutic products

Also Published As

Publication number Publication date
WO2003048730A3 (en) 2005-05-26
AU2002357779A1 (en) 2003-06-17
CA2478547A1 (en) 2003-06-12
EP1554576B8 (de) 2008-06-11
DE60222816D1 (de) 2007-11-15
EP1554576B1 (de) 2007-10-03
US7754433B2 (en) 2010-07-13
EP1554576B9 (de) 2008-08-20
WO2003048730A2 (en) 2003-06-12
EP1554576A4 (de) 2006-04-05
DE60222816T2 (de) 2008-07-03
EP1554576A2 (de) 2005-07-20
ES2294193T3 (es) 2008-04-01
CA2478547C (en) 2011-09-20
AU2002357779A8 (en) 2003-06-17
US20030186327A1 (en) 2003-10-02

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