ATE375144T1 - Echogene polymermikrokapseln und nanokapseln und verfahren zu ihrer herstellung und verwendung - Google Patents

Echogene polymermikrokapseln und nanokapseln und verfahren zu ihrer herstellung und verwendung

Info

Publication number
ATE375144T1
ATE375144T1 AT02757932T AT02757932T ATE375144T1 AT E375144 T1 ATE375144 T1 AT E375144T1 AT 02757932 T AT02757932 T AT 02757932T AT 02757932 T AT02757932 T AT 02757932T AT E375144 T1 ATE375144 T1 AT E375144T1
Authority
AT
Austria
Prior art keywords
capsules
production
echogenic polymer
polymer micro
nano
Prior art date
Application number
AT02757932T
Other languages
English (en)
Inventor
Margaret Wheatley
Dalia El-Sherif
Original Assignee
Univ Drexel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23072967&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE375144(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Drexel filed Critical Univ Drexel
Application granted granted Critical
Publication of ATE375144T1 publication Critical patent/ATE375144T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasonic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasonic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasonic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasonic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/225—Microparticles, microcapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5192—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Biomedical Technology (AREA)
  • Acoustics & Sound (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT02757932T 2001-03-30 2002-04-01 Echogene polymermikrokapseln und nanokapseln und verfahren zu ihrer herstellung und verwendung ATE375144T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28041201P 2001-03-30 2001-03-30

Publications (1)

Publication Number Publication Date
ATE375144T1 true ATE375144T1 (de) 2007-10-15

Family

ID=23072967

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02757932T ATE375144T1 (de) 2001-03-30 2002-04-01 Echogene polymermikrokapseln und nanokapseln und verfahren zu ihrer herstellung und verwendung

Country Status (7)

Country Link
EP (1) EP1390016B2 (de)
JP (1) JP2004532207A (de)
AT (1) ATE375144T1 (de)
AU (1) AU2002307056B2 (de)
CA (1) CA2441609C (de)
DE (1) DE60222888T3 (de)
WO (1) WO2002078611A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6919068B2 (en) * 2002-05-17 2005-07-19 Point Biomedical Corporation Method of preparing gas-filled polymer matrix microparticles useful for echographic imaging
US8615289B2 (en) * 2004-02-20 2013-12-24 Koninklijke Philips N.V. Drug application during a CT scan
WO2005099367A2 (en) * 2004-04-16 2005-10-27 Critical Care Innovations, Inc. Systems and methods for improving image-guided tissue ablation
EP1904179A2 (de) 2005-06-07 2008-04-02 Koninklijke Philips Electronics N.V. Verfahren und gerät zur ultraschall-arzneiabgabe und wärmetherapie mit phasenkonvertierbaren flüssigkeiten
WO2007137236A2 (en) * 2006-05-19 2007-11-29 Drexel University Drug loaded contrast agents: combining diagnosis and therapy
CN102227254B (zh) 2008-12-17 2014-08-13 道康宁公司 用于温度控制释放的硅酸盐壳微囊的悬浮液
US20120330132A1 (en) 2009-12-07 2012-12-27 Paul Sorajja Device for the Delineation of Cardiovascular or Other Anatomical Structures
US10285575B2 (en) 2012-07-02 2019-05-14 Cook Medical Technologies Llc Endoscopic access system having a detachable handle
JP6340415B2 (ja) 2013-05-31 2018-06-06 クック・メディカル・テクノロジーズ・リミテッド・ライアビリティ・カンパニーＣｏｏｋ Ｍｅｄｉｃａｌ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｌｌｃ アクセス針・スタイレットアセンブリ
WO2017089876A1 (en) * 2015-10-26 2017-06-01 Smiths Medical International Limited Echogenic needle assemblies and method of use thereof
JP7396735B1 (ja) * 2022-11-25 2023-12-12 三水株式会社 中空粒子の製造方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5585112A (en) * 1989-12-22 1996-12-17 Imarx Pharmaceutical Corp. Method of preparing gas and gaseous precursor-filled microspheres
AU636481B2 (en) * 1990-05-18 1993-04-29 Bracco International B.V. Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography
US5674468A (en) * 1992-03-06 1997-10-07 Nycomed Imaging As Contrast agents comprising gas-containing or gas-generating polymer microparticles or microballoons
US6080429A (en) * 1993-10-25 2000-06-27 Genentech, Inc. Method for drying microspheres
JP2887098B2 (ja) * 1994-10-26 1999-04-26 キヤノン株式会社 被記録媒体、その製造方法及び画像形成方法
US5611344A (en) * 1996-03-05 1997-03-18 Acusphere, Inc. Microencapsulated fluorinated gases for use as imaging agents
US5837221A (en) † 1996-07-29 1998-11-17 Acusphere, Inc. Polymer-lipid microencapsulated gases for use as imaging agents

Also Published As

Publication number Publication date
EP1390016B2 (de) 2012-06-20
DE60222888T2 (de) 2008-07-17
EP1390016A2 (de) 2004-02-25
CA2441609C (en) 2010-11-09
JP2004532207A (ja) 2004-10-21
EP1390016A4 (de) 2005-05-18
DE60222888D1 (de) 2007-11-22
WO2002078611A3 (en) 2003-02-27
CA2441609A1 (en) 2002-10-10
WO2002078611A2 (en) 2002-10-10
EP1390016B1 (de) 2007-10-10
DE60222888T3 (de) 2012-08-23
AU2002307056B2 (en) 2005-08-04

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