BRPI0410185A - composição para manter a viabilidade de um orgão e célula - Google Patents
composição para manter a viabilidade de um orgão e célulaInfo
- Publication number
- BRPI0410185A BRPI0410185A BRPI0410185-5A BRPI0410185A BRPI0410185A BR PI0410185 A BRPI0410185 A BR PI0410185A BR PI0410185 A BRPI0410185 A BR PI0410185A BR PI0410185 A BRPI0410185 A BR PI0410185A
- Authority
- BR
- Brazil
- Prior art keywords
- viability
- organ
- maintain
- cell
- composition
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/04—Preserving or maintaining viable microorganisms
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0693—Tumour cells; Cancer cells
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/10—Screening for compounds of potential therapeutic value involving cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Environmental Sciences (AREA)
- Dentistry (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Toxicology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Virology (AREA)
- Dermatology (AREA)
- Dispersion Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
"COMPOSIçãO PARA MANTER A VIABILIDADE DE UM óRGãO E CéLULA". A presente invenção está orientada a composições de nano partículas para manter a viabilidade de um órgão, tecido ou celular, quando os mesmos são separados a partir de suportes fisiológicos normais. As composições contêm composições de nano partículas e métodos de preservar os órgãos tais como rins, tanto in vivo como ex vivo, também são descritos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46920003P | 2003-05-09 | 2003-05-09 | |
| PCT/US2004/014551 WO2004101758A2 (en) | 2003-05-09 | 2004-05-07 | Composition for maintaining organ and cell viability |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0410185A true BRPI0410185A (pt) | 2006-05-16 |
Family
ID=32991004
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0410185-5A BRPI0410185A (pt) | 2003-05-09 | 2004-05-07 | composição para manter a viabilidade de um orgão e célula |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US7604933B2 (pt) |
| EP (3) | EP1475434A1 (pt) |
| JP (2) | JP5192694B2 (pt) |
| KR (1) | KR20060019525A (pt) |
| CN (2) | CN1784142A (pt) |
| AU (2) | AU2004236402B2 (pt) |
| BR (1) | BRPI0410185A (pt) |
| CA (2) | CA2526933C (pt) |
| MX (1) | MXPA05012070A (pt) |
| RU (1) | RU2005138320A (pt) |
| WO (2) | WO2004101758A2 (pt) |
| ZA (1) | ZA200509760B (pt) |
Families Citing this family (75)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1475434A1 (en) * | 2003-05-09 | 2004-11-10 | Oncoscience AG | Method for storing tumor cells |
| US7087369B2 (en) * | 2003-12-17 | 2006-08-08 | The Regents Of The University Of California | Cornea preservation medium |
| JP2005306749A (ja) * | 2004-04-19 | 2005-11-04 | Kringle Pharma Inc | Hgf含有臓器保存液 |
| US8304181B2 (en) | 2004-10-07 | 2012-11-06 | Transmedics, Inc. | Method for ex-vivo organ care and for using lactate as an indication of donor organ status |
| DK1768490T3 (da) | 2004-10-07 | 2010-10-11 | Transmedics Inc | Systemer og fremgangsmåder til ex-vivo-organpleje |
| US12010987B2 (en) | 2004-10-07 | 2024-06-18 | Transmedics, Inc. | Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status |
| US9078428B2 (en) | 2005-06-28 | 2015-07-14 | Transmedics, Inc. | Systems, methods, compositions and solutions for perfusing an organ |
| HUE051267T2 (hu) | 2005-12-13 | 2021-03-01 | Harvard College | Sejttranszplantációs állványok |
| KR100809046B1 (ko) * | 2006-03-10 | 2008-03-03 | 가톨릭대학교 산학협력단 | 풀루란을 가진 나노자가응집체 및 이의 이용방법 |
| CA2674949A1 (en) | 2007-01-12 | 2008-07-24 | J. Marc Simard | Targeting ncca-atp channel for organ protection following ischemic episode |
| BRPI0807918A2 (pt) * | 2007-02-17 | 2017-05-16 | Harvard College | composições e método para preservação de tecido |
| KR100834687B1 (ko) * | 2007-02-21 | 2008-06-02 | 주식회사 엘지생활건강 | 히노키티올 함유 지질 나노 입자 및 그의 제조방법 |
| US9457179B2 (en) | 2007-03-20 | 2016-10-04 | Transmedics, Inc. | Systems for monitoring and applying electrical currents in an organ perfusion system |
| KR100785656B1 (ko) * | 2007-05-14 | 2007-12-17 | 재단법인서울대학교산학협력재단 | 소염제로 사용되는 소디움글리코콜레이트 또는 그 유도체 |
| US9770535B2 (en) | 2007-06-21 | 2017-09-26 | President And Fellows Of Harvard College | Scaffolds for cell collection or elimination |
| FR2919785B1 (fr) * | 2007-08-09 | 2017-10-20 | Hemarina Sa | Utilisation d'une globine, d'un protomere de globine ou d'une hemoglobine extracellulaire pour la preservation d'organes, de tissus, ou de cellules d'organes ou de tissus, ou de culture de cellules |
| US9462802B2 (en) | 2008-01-31 | 2016-10-11 | Transmedics, Inc. | Systems and methods for ex vivo lung care |
| JP5690143B2 (ja) | 2008-02-13 | 2015-03-25 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 持続的細胞プログラミング装置 |
| US9370558B2 (en) | 2008-02-13 | 2016-06-21 | President And Fellows Of Harvard College | Controlled delivery of TLR agonists in structural polymeric devices |
| CN102574901B (zh) * | 2009-05-07 | 2016-08-03 | 埃玛里纳 | 新的血红蛋白及其用途 |
| US8389474B1 (en) * | 2009-07-14 | 2013-03-05 | Alan Anson Wanderer | Rationale for IL-1 β targeted therapy to improve harvested organ viability, allograft tolerance, replant success and for conditions characterized by reduced or absent arterial perfusion |
| CA2768552A1 (en) | 2009-07-31 | 2011-02-03 | President And Fellows Of Harvard College | Programming of cells for tolerogenic therapies |
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| RU2550917C2 (ru) * | 2010-02-23 | 2015-05-20 | Терумо Кабусики Каиса | Добавка и медицинский контейнер для обогащенной эритроцитами жидкости |
| US11202759B2 (en) | 2010-10-06 | 2021-12-21 | President And Fellows Of Harvard College | Injectable, pore-forming hydrogels for materials-based cell therapies |
| CN103502436A (zh) * | 2011-03-07 | 2014-01-08 | 麻省理工学院 | 用核酸转染细胞的方法 |
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| JP6359966B2 (ja) | 2011-04-28 | 2018-07-18 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 最小侵襲投与のための注射可能な予成形される肉眼的三次元スキャフォールド |
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| GB201107466D0 (en) | 2011-05-05 | 2011-06-15 | Loktionov Alexandre | Device and method for non-invasive collection of colorectal mucocellular layer and disease detection |
| WO2012167230A1 (en) | 2011-06-03 | 2012-12-06 | President And Fellows Of Harvard College | In situ antigen-generating cancer vaccine |
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| ES3030496T3 (en) | 2014-12-12 | 2025-06-30 | Transmedics Inc | Apparatus and method for organ perfusion |
| EP3250250A4 (en) | 2015-01-30 | 2019-05-22 | President and Fellows of Harvard College | PERITUMORAL AND INTRATUMORAL MATERIALS FOR CANCER THERAPY |
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| KR102344674B1 (ko) * | 2019-06-19 | 2021-12-29 | 가천대학교 산학협력단 | 8-옥소-2'-디옥시구아노신을 유효성분으로 포함하는 이식용 장기의 보존 시 장기손상 방지용 조성물 |
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- 2003-09-30 EP EP03022146A patent/EP1475434A1/en not_active Withdrawn
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- 2004-05-07 CA CA2526933A patent/CA2526933C/en not_active Expired - Fee Related
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- 2004-05-07 JP JP2006532912A patent/JP5192694B2/ja not_active Expired - Fee Related
- 2004-05-07 CN CNA2004800125711A patent/CN1784142A/zh active Pending
- 2004-05-07 EP EP04731585A patent/EP1623021A1/en not_active Withdrawn
- 2004-05-07 BR BRPI0410185-5A patent/BRPI0410185A/pt not_active IP Right Cessation
- 2004-05-07 AU AU2004236402A patent/AU2004236402B2/en not_active Ceased
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- 2004-05-07 RU RU2005138320/15A patent/RU2005138320A/ru not_active Application Discontinuation
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- 2004-05-07 US US10/841,756 patent/US7220538B2/en not_active Expired - Lifetime
- 2004-05-07 JP JP2006505398A patent/JP4870551B2/ja not_active Expired - Fee Related
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| CN1784142A (zh) | 2006-06-07 |
| CA2526933C (en) | 2013-02-12 |
| WO2004101758A3 (en) | 2005-08-11 |
| EP1475434A1 (en) | 2004-11-10 |
| AU2004239310A1 (en) | 2004-11-25 |
| CA2523417C (en) | 2013-04-30 |
| RU2005138320A (ru) | 2006-04-27 |
| US7604933B2 (en) | 2009-10-20 |
| CN1816617B (zh) | 2010-12-01 |
| WO2004099393A1 (en) | 2004-11-18 |
| JP4870551B2 (ja) | 2012-02-08 |
| US20050037330A1 (en) | 2005-02-17 |
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| CA2523417A1 (en) | 2004-11-18 |
| KR20060019525A (ko) | 2006-03-03 |
| EP1624750A4 (en) | 2006-10-25 |
| US7220538B2 (en) | 2007-05-22 |
| JP2007502130A (ja) | 2007-02-08 |
| CN1816617A (zh) | 2006-08-09 |
| US20070178435A1 (en) | 2007-08-02 |
| JP2007524368A (ja) | 2007-08-30 |
| EP1623021A1 (en) | 2006-02-08 |
| EP1624750A2 (en) | 2006-02-15 |
| EP1624750B1 (en) | 2015-12-30 |
| US20070042338A1 (en) | 2007-02-22 |
| AU2004236402B2 (en) | 2009-12-03 |
| US7537885B2 (en) | 2009-05-26 |
| AU2004239310B2 (en) | 2010-06-17 |
| WO2004101758A2 (en) | 2004-11-25 |
| AU2004236402A1 (en) | 2004-11-18 |
| JP5192694B2 (ja) | 2013-05-08 |
| ZA200509760B (en) | 2006-11-29 |
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