ATE376054T1 - Diacylglyzerin o-acyltransferase - Google Patents

Diacylglyzerin o-acyltransferase

Info

Publication number
ATE376054T1
ATE376054T1 AT98942283T AT98942283T ATE376054T1 AT E376054 T1 ATE376054 T1 AT E376054T1 AT 98942283 T AT98942283 T AT 98942283T AT 98942283 T AT98942283 T AT 98942283T AT E376054 T1 ATE376054 T1 AT E376054T1
Authority
AT
Austria
Prior art keywords
nucleic acid
well
acid compositions
applications
diacylglycerin
Prior art date
Application number
AT98942283T
Other languages
English (en)
Inventor
Robert Farese
Sylvaine Cases
Steven Smith
Sandra K Erickson
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Application granted granted Critical
Publication of ATE376054T1 publication Critical patent/ATE376054T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6463—Glycerides obtained from glyceride producing microorganisms, e.g. single cell oil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Physics & Mathematics (AREA)
  • Nutrition Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
AT98942283T 1998-06-24 1998-08-28 Diacylglyzerin o-acyltransferase ATE376054T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/103,754 US6344548B1 (en) 1998-06-24 1998-06-24 Diacylglycerol o-acyltransferase

Publications (1)

Publication Number Publication Date
ATE376054T1 true ATE376054T1 (de) 2007-11-15

Family

ID=22296862

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98942283T ATE376054T1 (de) 1998-06-24 1998-08-28 Diacylglyzerin o-acyltransferase

Country Status (7)

Country Link
US (1) US6344548B1 (de)
EP (1) EP1088088B8 (de)
AT (1) ATE376054T1 (de)
AU (1) AU758438B2 (de)
CA (1) CA2330549C (de)
DE (1) DE69838592T2 (de)
WO (1) WO1999067403A1 (de)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69816059T2 (de) 1997-02-10 2004-04-22 National Research Council Of Canada, Ottawa Gen, das für das pyruvat dehydrogenase kinase von pflanzen kodiert
US6166176A (en) * 1998-03-17 2000-12-26 Immvarx, Inc. Cancer marker protein and peptides thereof
US7135617B2 (en) * 1998-07-02 2006-11-14 Calgene Llc Diacylglycerol acyl transferase proteins
CA2851896C (en) 1998-12-02 2016-05-17 Karlene H. Butler Plant diacylglycerol acyltransferases
WO2000032793A2 (en) * 1998-12-04 2000-06-08 Calgene Llc Plant cell derived diacylglycerol acyltransferases
AU779969B2 (en) * 1998-12-17 2005-02-24 National Research Council Of Canada Diacylglycerol acyltransferase gene from plants
US7015373B1 (en) * 1998-12-17 2006-03-21 National Research Council Of Canada Diacylglycerol acyltransferase gene from plants
EP1173583A1 (de) * 1999-05-04 2002-01-23 Cargill, Incorporated Pflanzliche acyltransferasen
US6995301B1 (en) 1999-05-04 2006-02-07 Cargill, Incorporated Plant acyltransferases
US6552250B1 (en) 2000-06-14 2003-04-22 Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Agriculture And Agri-Food Diacylglycerol O-acyltransferase
US6444427B1 (en) 2000-07-11 2002-09-03 The Regents Of The University Of California Polymorphisms in a diacylglycerol acyltransferase gene, and methods of use thereof
AU2002224229B2 (en) * 2000-10-31 2007-11-29 Wouter Herman Robert Coppieters Marker assisted selection of bovine for improved milk production using diacylglycerol acyltransferase gene DGAT1
US20020119138A1 (en) 2001-02-26 2002-08-29 Sylvaine Cases Diacylglycerol o-acyltransferase 2alpha (DGAT2alpha)
US7045326B2 (en) 2001-02-23 2006-05-16 The Regents Of The University Of California Mono- and diacylglycerol acyltransferases and methods of use thereof
WO2003053363A2 (en) * 2001-12-19 2003-07-03 Millennium Pharmaceuticals, Inc. Human diacylglycerol acyltransferase 2 (dgat2) family members and uses therefor
JP4481819B2 (ja) * 2002-07-31 2010-06-16 モンサント テクノロジー エルエルシー ジアシルグリセロールアシルトランスフェラーゼ核酸配列および関連生成物
US20040185559A1 (en) 2003-03-21 2004-09-23 Isis Pharmaceuticals Inc. Modulation of diacylglycerol acyltransferase 1 expression
AR044152A1 (es) * 2003-05-09 2005-08-24 Bayer Corp Derivados de alquilarilo, metodo de preparacion y uso para el tratamiento de la obesidad
US7825235B2 (en) * 2003-08-18 2010-11-02 Isis Pharmaceuticals, Inc. Modulation of diacylglycerol acyltransferase 2 expression
AU2005209115A1 (en) * 2004-01-30 2005-08-11 Japan Tobacco Inc. Anorectic compounds
EP1789564B1 (de) * 2004-09-13 2012-01-04 Monsanto Technology LLC Promotormoleküle zur verwendung in pflanzen
US7550286B2 (en) 2004-11-04 2009-06-23 E. I. Du Pont De Nemours And Company Docosahexaenoic acid producing strains of Yarrowia lipolytica
US7273746B2 (en) * 2004-11-04 2007-09-25 E.I. Dupont De Nemours And Company Diacylglycerol acyltransferases for alteration of polyunsaturated fatty acids and oil content in oleaginous organisms
EP1831393A1 (de) * 2004-12-22 2007-09-12 Janssen Pharmaceutica N.V. Diacylglycerol-acyltransferase-assay
CA2693630C (en) 2006-07-14 2021-08-31 Commonwealth Scientific And Industrial Research Organisation Altering the fatty acid composition of rice
ES2397661T3 (es) 2006-08-04 2013-03-08 Isis Pharmaceuticals, Inc. Composiciones y sus usos dirigidos a la diacilglicerol aciltransferasa 1
EP2147109B1 (de) 2007-05-24 2014-03-19 E. I. Du Pont de Nemours and Company Dgat-gene aus yarrowia lipolytica für erhöhte samenfettproduktion sowie veränderte fettsäureprofile in sojabohnen
AU2009245975A1 (en) * 2008-05-16 2009-11-19 The Governors Of The University Of Alberta High throughput methods of identifying neutral lipid synthases
BRPI0908694A2 (pt) 2008-05-23 2019-09-24 Du Pont ''sementes de grão de soja transgência e método para aumentar o teor de ácido graxo total de uma semente de grão de soja''
WO2009143397A2 (en) 2008-05-23 2009-11-26 E. I. Du Pont De Nemours And Company Novel dgat genes for increased seed storage lipid production and altered fatty acid profiles in oilseed plants
EP2620501A3 (de) 2008-05-23 2013-10-02 E. I. du Pont de Nemours and Company DGAT-Gene aus ölhaltigen Organismen für erhöhte Samenfettproduktion sowie veränderte Fettsäureprofile bei Ölsamenpflanzen
CA2768737A1 (en) * 2008-07-21 2010-01-28 Commonwealth Scientific And Industrial Research Organisation Improved vegetable oils and uses therefor
WO2010009499A1 (en) 2008-07-21 2010-01-28 Commonwealth Scientific And Industrial Research Organisation Improved cottonseed oil and uses
AR078829A1 (es) 2009-10-30 2011-12-07 Du Pont Plantas y semillas con niveles alterados de compuesto de almacenamiento, construcciones relacionadas y metodos relacionados con genes que codifican proteinas similares a las aldolasas bacterianas de la clase ii del acido 2,4- dihidroxi-hept-2-eno-1,7-dioico
EP2504441B1 (de) 2009-11-23 2020-07-22 E. I. du Pont de Nemours and Company Saccharosetransportergene für steigerung des lipidgehaltes der pflanzensamen
NZ602125A (en) 2010-03-30 2014-01-31 Novartis Ag Uses of dgat1 inhibitors
CA2804025C (en) 2010-06-28 2023-02-21 Commonwealth Scientific And Industrial Research Organisation Methods of producing lipids
CA2860220C (en) 2011-12-22 2021-07-13 E. I. Du Pont De Nemours And Company Use of the soybean or medicago truncatula sucrose synthase promoter to increase plant seed oil content
AR089442A1 (es) 2011-12-27 2014-08-20 Commw Scient Ind Res Org Procesos para producir lipidos
US8809026B2 (en) 2011-12-27 2014-08-19 Commonwealth Scientific And Industrial Research Organisation Processes for producing lipids
US11639507B2 (en) 2011-12-27 2023-05-02 Commonwealth Scientific And Industrial Research Organisation Processes for producing lipids
WO2013159149A1 (en) 2012-04-25 2013-10-31 Commonwealth Scientific And Industrial Research Organisation High oleic acid oils
MX359167B (es) 2012-10-30 2018-09-18 Agresearch Ltd Polinucleotidos, polipeptidos y metodos de uso novedosos de aciltransferasa.
AU2013340445B2 (en) 2012-10-30 2019-08-22 New Zealand Institute For Bioeconomy Science Limited Improved acyltransferase polynucleotides, polypeptides, and methods of use
NZ706832A (en) 2012-10-30 2019-04-26 Agresearch Ltd Enhanced acyltransferase polynucleotides, polypeptides, and methods of use
CN109576241A (zh) 2012-12-21 2019-04-05 新西兰植物和食品研究院有限公司 基因表达的调控
WO2015164457A1 (en) 2014-04-22 2015-10-29 E. I. Du Pont De Nemours And Company Plastidic carbonic anhydrase genes for oil augmentation in seeds with increased dgat expression
MY178434A (en) 2014-07-07 2020-10-13 Commw Scient Ind Res Org Processes for producing industrial products from plant lipids
MX2018000412A (es) 2015-07-10 2018-03-14 Ionis Pharmaceuticals Inc Moduladores de diaciglicerol aciltransferasa 2 (dgat2).
MX2019002483A (es) 2016-09-02 2019-09-09 Commw Scient Ind Res Org Plantas con rasgos modificados.
EA202092190A1 (ru) 2018-03-16 2020-11-19 Анджи Фармасьютикалз Инк. Композиции и способы для лечения сильного запора
WO2023085931A1 (en) 2021-11-11 2023-05-19 Koninklijke Nederlandse Akademie Van Wetenschappen Hepatic organoids

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3225997A (en) 1996-05-30 1998-01-05 Trustees Of Columbia University In The City Of New York, The Dna encoding acylcoenzyme a: cholesterol acyltransferase and uses thereof

Also Published As

Publication number Publication date
EP1088088A1 (de) 2001-04-04
EP1088088B8 (de) 2007-11-21
DE69838592T2 (de) 2008-07-24
CA2330549C (en) 2010-04-20
EP1088088A4 (de) 2004-05-06
EP1088088B1 (de) 2007-10-17
AU9037698A (en) 2000-01-10
DE69838592D1 (de) 2007-11-29
WO1999067403A1 (en) 1999-12-29
US6344548B1 (en) 2002-02-05
CA2330549A1 (en) 1999-12-29
AU758438B2 (en) 2003-03-20

Similar Documents

Publication Publication Date Title
DE69838592D1 (de) Diacylglyzerin o-acyltransferase
DE69939426D1 (de) Diacylglycerin o-acyltransferase
BR9910251A (pt) Estimulação hematopoiética
FI945793A7 (fi) DNA-sekvenssejä, joita käytetään rekombinanttisen ihmis-BSSL/CEL:n val mistuksessa transgeenisissä ei-ihmisnisäkkäissä, ja valmistettu BSSL/C EL, jota käytetään pikkulasten formulaateissa
GR3033630T3 (en) Gene expression elements and the production of chimeric mouse-human antibodies.
DE68924026D1 (de) Biosensor und dessen herstellung.
ES2109945T3 (es) Composiciones y procedimientos para identificar moleculas biologicamente activas.
IL177228A0 (en) Use of a vector for the manufacture of a medicament for treating gaucher disease
DE69738581D1 (de) Menschliche dnase i hyperaktive varianten
AU2003266214A1 (en) Human coagulation factor vii polypeptides
CA2026915A1 (en) Stem cell factor
DE3879975D1 (de) Demethylavermectine und herstellung dazu.
ATE265204T1 (de) Micropartikeln zur verwendung in nadellosen injektion
ID25950A (id) Katalis-katalis untuk memproduksi aldehid tidak jenuh dan asam karboksilat tidak jenuh dan proses untuk produksi aldehid tidak jenuh dan asam karboksilat tidak jenuh menggunakan katalis
TW200407425A (en) Human coagulation factor VII polypeptides
ID30116A (id) Turunan-turunan piridopiranoazepin, pembuatannya dan penggunaan terapinya
DE69613329D1 (de) Enzym enthaltendes Granulat, Herstellungsmethode und das Granulat enthaltende Zusammensetzungen
DE3682882D1 (de) Menschliches immunoglobulin-g-fc-region-protein und dessen herstellung.
DE69532485D1 (de) Trehalose-freisetzendes Enzym, dafür kodierende DNA, Herstellung und Verwendung
WO1997009420A3 (en) Dna sequences coding for a human metalloproteinase and variants thereof
DE60025544D1 (de) Protein, das die Spaltung von Beta-Carotin katalysiert
DE3681368D1 (de) Polymere produkte, zusammensetzungen, deren herstellung und verwendung.
DE3674789D1 (de) Balken und dessen herstellung.
DE3677848D1 (de) Chromosomale dna-sequenz, expressionsvektor fuer menschlichen gewebeplasminogen aktivierenden faktor mit diesem transfektierte, gezuechtete zellen, sowie verfahren zur herstellung des genannten aktivierungsfaktors.
ITRM930818A0 (it) Procedimento per la produzione in piante di anticorpi ingegnerizzati, anticorpi prodotti e loro uso in diagnosi e terapia.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties