ATE376850T1 - Vorrichtung zum behandeln einen lungengefässverengung und von asthma - Google Patents

Vorrichtung zum behandeln einen lungengefässverengung und von asthma

Info

Publication number
ATE376850T1
ATE376850T1 AT97105021T AT97105021T ATE376850T1 AT E376850 T1 ATE376850 T1 AT E376850T1 AT 97105021 T AT97105021 T AT 97105021T AT 97105021 T AT97105021 T AT 97105021T AT E376850 T1 ATE376850 T1 AT E376850T1
Authority
AT
Austria
Prior art keywords
nitric oxide
vessor
asthma
construction
treating pulmonary
Prior art date
Application number
AT97105021T
Other languages
English (en)
Inventor
Warren M Zapol
Claes Frostell
Original Assignee
Gen Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27089304&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE376850(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gen Hospital Corp filed Critical Gen Hospital Corp
Application granted granted Critical
Publication of ATE376850T1 publication Critical patent/ATE376850T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/131—Amines acyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/0266—Nitrogen (N)
    • A61M2202/0275—Nitric oxide [NO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Saccharide Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Glass Compositions (AREA)
  • Exhaust Gas Treatment By Means Of Catalyst (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT97105021T 1990-12-05 1991-12-05 Vorrichtung zum behandeln einen lungengefässverengung und von asthma ATE376850T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62286590A 1990-12-05 1990-12-05
US76723491A 1991-09-27 1991-09-27

Publications (1)

Publication Number Publication Date
ATE376850T1 true ATE376850T1 (de) 2007-11-15

Family

ID=27089304

Family Applications (3)

Application Number Title Priority Date Filing Date
AT04029366T ATE367842T2 (de) 1990-12-05 1991-12-05 Verwendung von no zur behandlung der persistenten pulmonaren hypertonie des neugeborenen
AT92902708T ATE158509T1 (de) 1990-12-05 1991-12-05 Verwendung von no zur behandlung oder prävention der bronchokonstriktion
AT97105021T ATE376850T1 (de) 1990-12-05 1991-12-05 Vorrichtung zum behandeln einen lungengefässverengung und von asthma

Family Applications Before (2)

Application Number Title Priority Date Filing Date
AT04029366T ATE367842T2 (de) 1990-12-05 1991-12-05 Verwendung von no zur behandlung der persistenten pulmonaren hypertonie des neugeborenen
AT92902708T ATE158509T1 (de) 1990-12-05 1991-12-05 Verwendung von no zur behandlung oder prävention der bronchokonstriktion

Country Status (16)

Country Link
US (2) US5873359A (de)
EP (4) EP1875917A3 (de)
JP (3) JP2701978B2 (de)
AT (3) ATE367842T2 (de)
AU (1) AU657726B2 (de)
CA (1) CA2097823C (de)
DE (9) DE69133584D1 (de)
DK (3) DK1516639T4 (de)
EE (1) EE03119B1 (de)
ES (3) ES2132043T3 (de)
GR (3) GR960300032T1 (de)
LU (3) LU90886I2 (de)
LV (1) LV12201B (de)
NL (3) NL300081I2 (de)
SG (1) SG47527A1 (de)
WO (1) WO1992010228A1 (de)

Families Citing this family (289)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5570683A (en) * 1990-12-05 1996-11-05 The General Hospital Corporation Methods and devices for treating pulmonary vasoconstriction and asthma
EP1875917A3 (de) * 1990-12-05 2012-11-28 The General Hospital Corporation Gasmischung zur Behandlung von Lungengefässverengung
GB9027234D0 (en) * 1990-12-15 1991-02-06 Harris Pharma Ltd An inhalation device
US5380758A (en) * 1991-03-29 1995-01-10 Brigham And Women's Hospital S-nitrosothiols as smooth muscle relaxants and therapeutic uses thereof
AU651882B2 (en) * 1991-05-14 1994-08-04 Visiomed Group Limited Aerosol inhalation device
US6119688A (en) * 1991-08-26 2000-09-19 3M Innovative Properties Company Powder dispenser
DE4208880A1 (de) * 1992-03-19 1993-09-23 Boehringer Ingelheim Kg Separator fuer pulverinhalatoren
FR2695831B1 (fr) * 1992-09-24 1994-11-10 Air Liquide Installation et procédé de fourniture d'un mélange gazeux aux voies respiratoires d'un utilisateur.
WO1994023772A2 (en) * 1993-04-06 1994-10-27 Minnesota Mining And Manufacturing Company Deagglomerators for dry powder inhalers
US5427797A (en) * 1993-04-06 1995-06-27 Brigham And Women's Hospital Systemic effects of nitric oxide inhalation
DE59409834D1 (de) * 1993-04-17 2001-09-27 Messer Griesheim Austria Ges M Gerät zur kontrollierten Zudosierung von NO zur Atemluft von Patienten
JP3248533B2 (ja) * 1993-07-06 2002-01-21 アエロクライン・アクチボラゲット 呼気中のｎｏレベルの測定に使用されるシステムおよび異常ｎｏレベルに関連する疾患の診断方法
SE9302478L (sv) * 1993-07-22 1994-11-07 Siemens Elema Ab Gasblandning och apparat för att tillföra gasblandningen till lungorna hos ett levande väsen
DE4327732C1 (de) * 1993-08-18 1994-09-01 Messer Griesheim Gmbh NO-haltiges Gasgemisch zur Behandlung pulmonaler Erkrankungen
DE4327731C1 (de) * 1993-08-18 1994-11-10 Messer Griesheim Gmbh NO-haltiges Gasgemisch zur Behandlung pulmonaler Erkrankungen
GB9320978D0 (en) * 1993-10-12 1993-12-01 Higenbottam Timohy W Nitric oxide treatment
US5558083A (en) * 1993-11-22 1996-09-24 Ohmeda Inc. Nitric oxide delivery system
AU700162B2 (en) * 1994-05-13 1998-12-24 Aradigm Corporation Narcotic containing aerosol formulation
DE4419860A1 (de) * 1994-06-07 1995-12-14 Hoechst Ag Verfahren und Filter zur Herstellung von NO¶2¶-freiem Stickstoffmonoxid mit schwefelhaltigen Polymeren
US5615669A (en) * 1994-07-22 1997-04-01 Siemens Elema Ab Gas mixture and device for delivering the gas mixture to the lungs of a respiratory subject
US6063407A (en) * 1995-02-16 2000-05-16 The General Hospital Corporation Treatment of vascular thrombosis and restenosis with inhaled nitric oxide
US5665077A (en) * 1995-04-24 1997-09-09 Nitrosci Pharmaceuticals Llc Nitric oxide-releasing nitroso compositions and methods and intravascular devices for using them to prevent restenosis
SE506208C2 (sv) * 1995-07-05 1997-11-24 Aerocrine Systems Kb Anordning för uppsamling av gas från de övre luftvägarna och leverans av denna gas till inandningsluften i en respirator
RU2072241C1 (ru) * 1995-09-20 1997-01-27 Панина Елена Владимировна Способ формирования дыхательной газовой смеси и аппарат для его осуществления
DE69618133T2 (de) * 1995-10-13 2002-07-11 Siemens-Elema Ab, Solna Trachealtubus und Vorrichtung für Beatmungssysteme
WO1997015311A1 (fr) * 1995-10-20 1997-05-01 L'air Liquide, Societe Anonyme Pour L'etude Et L'exploitation Des Procedes Georges Claude Composition a base de monoxyde d'azote en tant que medicament
WO1997018000A1 (en) * 1995-11-13 1997-05-22 Brigham And Women's Hospital S-nitroso-hemoglobin and therapeutic uses thereof
US5699790A (en) * 1996-03-21 1997-12-23 Ohmeda Inc. System for predicting NO2 concentrations
ES2267141T3 (es) * 1996-04-05 2007-03-01 The General Hospital Corporation Tratamiento de una hemoglobinopatia.
US5765548A (en) * 1996-05-07 1998-06-16 Perry; Bryan J. Use of nitric oxide in the treatment of exercised induced pulmonary hemorrhaging in equine
US5811437A (en) * 1996-05-21 1998-09-22 Eli Lilly And Company Methods of increasing nitric oxide synthesis
CA2206477A1 (en) 1996-07-10 1998-01-10 Ohmeda Inc. System for correcting no2 monitor
US5732694A (en) * 1996-12-13 1998-03-31 Ohmeda Inc. System for correcting NO2 monitor
CA2260771A1 (en) * 1996-07-17 1998-01-22 The General Hospital Corporation Method of inducing vasodilation and treating pulmonary hypertension using adenoviral-mediated transfer of the nitric oxide synthase gene
US6720309B1 (en) 1996-07-17 2004-04-13 Leuven Research And Development, V.Z.W. Method of inducing vasodilation and treating pulmonary hypertension using adenoviral-mediated transfer of the nitric oxide synthase gene
JP3880103B2 (ja) * 1996-07-18 2007-02-14 住友精化株式会社 医療用一酸化窒素混合ガスおよびその製造方法
SE506778C2 (sv) * 1996-08-12 1998-02-09 Siemens Elema Ab Förfarande vid blandning av gaser och en anordning för blandning av gaser
AU3901497A (en) * 1996-08-13 1998-03-06 University Of Massachusetts Nitric oxide sensor
DE19734279A1 (de) * 1997-08-07 1999-02-11 Messer Griesheim Gmbh Wasserstoffhaltiges Medikament
US5732693A (en) 1996-10-02 1998-03-31 Ohmeda Inc. Pause control of nitric oxide therapy
JP2001517108A (ja) 1997-01-17 2001-10-02 メッサー オーストリア ゲゼルシャフト ミット ベシュレンクテル ハフツング 制御されるガス供給システム
US6027713A (en) * 1997-03-06 2000-02-22 Meri Charmyne Russell Composition and method for the treatment of exercise induced pulmonary hemorrhage
SE9700940D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Powder inhaler IV
CA2225013C (en) 1997-04-04 2006-06-06 Institut Du N.O. Inc. Injection system for delivery of a gaseous substance
WO1998046277A2 (en) * 1997-04-16 1998-10-22 Ohmeda, Inc. Humidity compensation for fuel cell zeroing in respiratory gas measurement
US5918596A (en) * 1997-04-22 1999-07-06 Instrumentarium Corp. Special gas dose delivery apparatus for respiration equipment
FR2762992B1 (fr) * 1997-05-07 2000-08-25 Air Liquide Transporteurs de no a base de complexes polyazamacrocycles de fer et de cobalt
US6125846A (en) * 1997-05-16 2000-10-03 Datex-Ohmeda, Inc. Purge system for nitric oxide administration apparatus
US6656452B1 (en) * 1997-10-21 2003-12-02 The General Hospital Corporation Use of inhaled NO as anti-inflammatory agent
US6109260A (en) * 1998-02-18 2000-08-29 Datex-Ohmeda, Inc. Nitric oxide administration device with timed pulse
US6142147A (en) * 1998-03-31 2000-11-07 The General Hospital Corporation Nasal delivery system for inhaled nitric oxide
CA2254645A1 (en) * 1998-11-23 2000-05-23 Pulmonox Medical Corporation Method and apparatus for treatment of respiratory infections by nitric oxide inhalation
US20070086954A1 (en) * 1998-11-23 2007-04-19 Miller Christopher C Method and apparatus for treatment of respiratory infections by nitric oxide inhalation
JP3641151B2 (ja) * 1999-02-04 2005-04-20 帝人株式会社 治療用ガス投入用呼吸マスク
US6346382B1 (en) * 1999-06-01 2002-02-12 Vanderbilt University Human carbamyl phosphate synthetase I polymorphism and diagnostic methods related thereto
US9486429B2 (en) * 1999-06-01 2016-11-08 Vanderbilt University Therapeutic methods employing nitric oxide precursors
FR2795644B1 (fr) * 1999-07-02 2004-07-30 Air Liquide Sante Int Utilisations therapeutiques d'un melange helium/oxygene, en particulier dans le traitement de l'asthme
JP4932109B2 (ja) * 1999-07-12 2012-05-16 キャプニア インコーポレイテッド 頭痛、鼻炎及び他のありふれた病気を治す方法及び装置
CA2680378C (en) * 1999-08-02 2013-09-24 Duke University Method for determining physiological effects of hemoglobin
US7045152B2 (en) * 1999-09-08 2006-05-16 Duke University Treating pulmonary disorders with gaseous agent causing repletion of GSNO
US6314956B1 (en) 1999-09-08 2001-11-13 Duke University Pulmonary delivery of NO group-containing compound in gas form to treat respiratory, cardiac and blood disorders
US6694969B1 (en) 1999-09-22 2004-02-24 Instrumentarium Corp. Method to improve oxygenation in subjects suffering impaired oxygenation
DE60027403T2 (de) 1999-09-22 2006-10-19 Instrumentarium Corp. Verbesserung der Sauerstoffversorgung in Lebewesen mit gestörter Sauerstoffversorgung
US6612306B1 (en) 1999-10-13 2003-09-02 Healthetech, Inc. Respiratory nitric oxide meter
EP1223931B1 (de) * 1999-10-29 2005-12-14 Orion Corporation Verwendung eines imidazolderivats zur behandlung oder verhütung von hypotension und schock
SE9903985D0 (sv) * 1999-11-03 1999-11-03 Aga Ab Use of nitric oxide
DE60027921D1 (de) * 1999-11-08 2006-06-14 Capnia Inc Vorrichtung zur gleichzeitigen verabreichung von gasen und medikamenten
US20060172017A1 (en) * 1999-11-08 2006-08-03 Capnia, Incorporated Methods and apparatus for the enhanced delivery of physiologic agents to tissue surfaces
US20070039615A1 (en) * 1999-11-08 2007-02-22 Capnia, Incorporated Methods and apparatus for treating rhinitis
US7516742B2 (en) * 1999-11-24 2009-04-14 Cardinal Health 207, Inc. Method and apparatus for delivery of inhaled nitric oxide to spontaneous-breathing and mechanically-ventilated patients with intermittent dosing
US6581599B1 (en) * 1999-11-24 2003-06-24 Sensormedics Corporation Method and apparatus for delivery of inhaled nitric oxide to spontaneous-breathing and mechanically-ventilated patients
US6758214B2 (en) 2000-01-28 2004-07-06 Cyterra Corporation Simple nitric oxide generator for ambulatory and/or bedside inhaled no treatment
US20030026766A1 (en) * 2000-04-13 2003-02-06 Mark Sanders Medicaments for treating respiratory disorders comprising formoterol and fluticasone
US6601580B1 (en) 2000-06-28 2003-08-05 The General Hospital Corporation Enhancing therapeutic effectiveness of nitric oxide inhalation
US6951215B1 (en) * 2000-07-14 2005-10-04 Tufts University Drug delivery device for animals
KR20030065463A (ko) * 2000-08-11 2003-08-06 데이비드 알. 휘트록 질소 산화물 및 질소 산화물 전구체의 생산을 증가시키기위한 암모니아 산화 박테리아를 포함하는 조성물 및 이를이용하는 방법
AU2001296456A1 (en) 2000-09-29 2002-04-08 Healthetech, Inc. Indirect calorimetry system
US6668828B1 (en) 2000-10-16 2003-12-30 Pulmonox Technologies Corporations System and elements for managing therapeutic gas administration to a spontaneously breathing non-ventilated patient
SE0004229D0 (sv) * 2000-11-17 2000-11-17 Aga Ab Inhalation of nitric oxide
US7335181B2 (en) * 2000-12-26 2008-02-26 Pulmonox Technologies Corporation Nitric oxide decontamination of the upper respiratory tract
US6432077B1 (en) * 2000-12-26 2002-08-13 Sensormedics Corporation Device and method for treatment of surface infections with nitric oxide
US7122018B2 (en) * 2000-12-26 2006-10-17 Sensormedics Corporation Device and method for treatment of wounds with nitric oxide
AUPR315401A0 (en) * 2001-02-16 2001-03-15 Resmed Limited An apparatus for supplying clean breathable gas
WO2002087673A1 (de) * 2001-04-25 2002-11-07 Messer Austria Gmbh Aerosoldosiergerät
US6749834B2 (en) * 2001-06-19 2004-06-15 World Precision Instruments, Inc. Methods and apparatus for therapeutic treatment of respiratory, cardiac and other pathologies
EP1429829B1 (de) * 2001-09-05 2013-11-27 Geno LLC Stickoxid-erzeugung
US6575918B2 (en) 2001-09-27 2003-06-10 Charlotte-Mecklenburg Hospital Non-invasive device and method for the diagnosis of pulmonary vascular occlusions
US20030070674A1 (en) * 2001-10-12 2003-04-17 Bryan Perry Use of aerosolized compounds in the treatment of exercise induced pulmonary hemorrhage in an equine
GB0125222D0 (en) * 2001-10-19 2001-12-12 Barts & London Nhs Trust Composition for the treatment of microbial infections
US20040110691A1 (en) * 2001-11-13 2004-06-10 Stamler Jonathan S. Thiol reactive agents as a therapeutic modality
US6627602B2 (en) * 2001-11-13 2003-09-30 Duke University Preventing desensitization of receptors
US6472390B1 (en) * 2001-11-13 2002-10-29 Duke University Use of therapeutic dosages for nitric oxide donors which do not significantly lower blood pressure or pulmonary artery pressure
CN1308438C (zh) * 2002-01-11 2007-04-04 大卫·R·怀特洛克 含有氨氧化细菌的化合物以及使用的方法
US20030170223A1 (en) * 2002-02-01 2003-09-11 Board Of Trustees Of Michigan State University Pulmonary vasodilator surfactant compositions and method of use
US7086397B2 (en) * 2002-02-16 2006-08-08 Graham Lindley Spruiell Patient usable emergency medical kit
US20060088942A1 (en) * 2002-05-29 2006-04-27 Stamler Jonathan S Measuring nitric oxide in blood gases and treatments based thereon
CN1674942A (zh) * 2002-06-21 2005-09-28 联邦高等教育系统匹兹堡大学 氧化氮、血红素加氧酶－1和血红素降解产物的药学用途
AU2003247834A1 (en) * 2002-06-28 2004-01-19 The Research Foundation Of State University Of New York Therapeutic agent delivery device and method
US7681572B2 (en) * 2002-08-20 2010-03-23 Aga Ab Method and devices for administration of therapeutic gases
AU2003259897B2 (en) * 2002-08-20 2008-04-03 Aga Ab Methods and devices for administration of therapeutic gases
US7337776B2 (en) * 2002-08-20 2008-03-04 Aga Ab Methods for easing pain and anxiety from atrial or ventricular defibrillation
US8001962B2 (en) * 2002-08-23 2011-08-23 Sheiman Ultrasonic Research Foundation Pty Ltd. Nebulizing and drug delivery device
US6869402B2 (en) * 2002-08-27 2005-03-22 Precision Pulsus, Inc. Method and apparatus for measuring pulsus paradoxus
US7828739B2 (en) * 2002-08-27 2010-11-09 Precision Pulsus, Inc. Apnea detection system
US7531133B2 (en) * 2002-09-10 2009-05-12 Pulmonox Technologies Corporation Use of nitric oxide gas in an extracorporeal circuitry to treat blood plasma
US20060128810A1 (en) * 2002-10-10 2006-06-15 Kyoto University Remedies for allergic diseases
US9138707B2 (en) 2002-12-10 2015-09-22 Sy Kimball Portable, nitric oxide generator
CA2413834A1 (en) * 2002-12-10 2004-06-10 1017975 Alberta Limited Nitric oxide gas generator
SE0300971D0 (sv) * 2003-04-03 2003-04-03 Aga Ab Nitric oxide in treatment of inflammation
US20040265238A1 (en) * 2003-06-27 2004-12-30 Imtiaz Chaudry Inhalable formulations for treating pulmonary hypertension and methods of using same
JP5564158B2 (ja) * 2003-07-09 2014-07-30 ザ ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ アズ リプレゼンテッド バイ ザ セクレタリー オブ ザ デパートメント オブ ヘルス アンド ヒューマン サービシーズ 亜硝酸塩によって特定の心臓血管状態を処置する方法
EP1667646A4 (de) * 2003-09-26 2007-07-04 David R Whitlock Verfahren zur verwendung von ammoniak-oxidierenden bakterien
US7552731B2 (en) * 2003-11-14 2009-06-30 Remcore, Inc. Remote control gas regulation system
WO2005077005A2 (en) * 2004-02-04 2005-08-25 The General Hospital Corporation Enhancing the effectiveness of an inhaled therapeutic gas
US20050191245A1 (en) * 2004-02-27 2005-09-01 Adams Christopher P. Nasal administration of calcium channel, blockers for treatment of hypertension and other cardiovascular disorders
CA2557814A1 (en) * 2004-03-01 2005-09-15 Lumen Therapeutics, Llc Compositions and methods for treating diseases
US7994225B2 (en) * 2004-03-17 2011-08-09 Rempex Pharmaceuticals, Inc. Bacterial efflux pump inhibitors for the treatment of ophthalmic and otic infections
JP2008500965A (ja) * 2004-03-17 2008-01-17 エムペックス・ファーマシューティカルズ・インコーポレーテッド 細菌の排出ポンプ阻害剤の使用および投与
US20080029093A1 (en) * 2004-05-11 2008-02-07 Alex Stenzler Intermittent Dosing Of Nitric Oxide Gas
US8518457B2 (en) * 2004-05-11 2013-08-27 Pulmonox Technologies Corporation Use of inhaled gaseous nitric oxide as a mucolytic agent or expectorant
US7362274B1 (en) * 2004-07-09 2008-04-22 Huan-Cheng Lien Coupled feed-in butterfly shaped left/right hand circularly polarized microstrip antenna
US7618594B2 (en) 2004-08-18 2009-11-17 Geno Llc Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
AU2005277397B2 (en) * 2004-08-18 2011-08-25 VERO Biotech LLC. Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
US20070154570A1 (en) * 2004-09-29 2007-07-05 Miller Christopher C Use of nitric oxide in the treatment and disinfection of biofilms
US8056557B2 (en) * 2005-03-09 2011-11-15 Ric Investments, Llc Nebulizing drug delivery device with barrier
US7721729B2 (en) * 2005-03-09 2010-05-25 Ric Investments, Llc Nebulizing drug delivery device for ventilator
US7814901B2 (en) * 2005-03-09 2010-10-19 Ric Investments, Llc Nebulizing drug delivery device with increased flow rate
US7631643B2 (en) 2005-03-09 2009-12-15 Ric Investments, Llc Nebulizing drug delivery device with interlock detection and temperature protection
WO2006125123A2 (en) * 2005-05-19 2006-11-23 University Of Cincinnati Methods for treating bacterial respiratory tract infections in an individual using acidified nitrite
WO2006125251A1 (en) * 2005-05-23 2006-11-30 Biosonic Australia Pty. Ltd. Apparatus for atomisation and liquid filtration
US8893717B2 (en) 2005-09-21 2014-11-25 Ino Therapeutics Llc Systems and methods of administering a pharmaceutical gas to a patient
US7523752B2 (en) 2005-09-21 2009-04-28 Ino Therapeutics, Llc System and method of administering a pharmaceutical gas to a patient
US7566308B2 (en) * 2005-10-13 2009-07-28 Cardiac Pacemakers, Inc. Method and apparatus for pulmonary artery pressure signal isolation
US20070116785A1 (en) * 2005-11-18 2007-05-24 Miller Christopher C Nitric oxide as an anti-viral agent, vaccine and vaccine adjuvant
DK1962869T3 (da) * 2005-12-21 2013-06-24 Solaeromed Inc Behandling af luftvejssygdomme
US8790715B2 (en) 2006-02-16 2014-07-29 Ino Therapeutics Llc Method and apparatus for generating nitric oxide for medical use
US20100313883A1 (en) * 2006-04-20 2010-12-16 Koninklijke Philips Electronics N.V. Ultrasonic bebulilzer with metal coated ultrasonic genrator
US9259535B2 (en) 2006-06-22 2016-02-16 Excelsior Medical Corporation Antiseptic cap equipped syringe
US11229746B2 (en) 2006-06-22 2022-01-25 Excelsior Medical Corporation Antiseptic cap
EP1903003B1 (de) 2006-07-05 2017-07-05 BSN medical GmbH Verfahren zur photolytischen Erzeugung von Stickstoffmonoxid
US8079998B2 (en) * 2006-10-20 2011-12-20 Pulmonox Technologies Corporation Methods and devices for the delivery of therapeutic gases including nitric oxide
EP2514473A1 (de) * 2006-11-07 2012-10-24 The General Hospital Corporation Vorrichtung zur Zuführung von Stickoxid
WO2008079993A2 (en) * 2006-12-22 2008-07-03 Ikaria, Inc. Combinations of nitric oxide and sulfide and methods of use and manufacture thereof
US20080193566A1 (en) * 2007-02-09 2008-08-14 Miller Christopher C Use of high dose concentrations of gaseous nitric oxide
US8176915B2 (en) * 2007-03-15 2012-05-15 Koninklijke Philips Electronics N.V. End-tidal gas estimation system and method
US8166971B2 (en) * 2007-03-15 2012-05-01 Ric Investments, Llc End-tidal gas estimation system and method
EP2131903B1 (de) * 2007-03-23 2018-01-24 Geno LLC Umwandlung von stickstoffdioxid (no2) in stickoxid (no)
US8466187B2 (en) 2007-09-18 2013-06-18 Thermolife International, Llc Amino acid compositions
WO2009048521A1 (en) * 2007-10-11 2009-04-16 Duke University Potentiating the effect of compound comprising nitric oxide
EP2534957B1 (de) 2007-12-14 2015-05-27 AeroDesigns, Inc Abgabe von Aerosol-sprühbaren Produkten
EP2237788A4 (de) * 2007-12-27 2013-06-05 Aires Pharmaceuticals Inc Aerosolisierte nitrit- und stickoxidspendende verbindungen und ihre verwendung
CA2713049C (en) 2008-01-28 2017-02-28 Geno Llc Conversion of nitrogen dioxide (no2) to nitric oxide (no)
US8720436B2 (en) * 2008-01-31 2014-05-13 Genosys, Inc. Nitric oxide gel apparatus and method
JP5623916B2 (ja) 2008-01-31 2014-11-12 バンダービルト・ユニバーシティＶａｎｄｅｒｂｉｌｔ Ｕｎｉｖｅｒｓｉｔｙ 動脈瘤性くも膜下出血及び血管痙攣に対する医薬組成物
US8434475B2 (en) * 2008-01-31 2013-05-07 Genosys, Inc. Nitric oxide reactor and distributor apparatus and method
KR20170005155A (ko) * 2008-01-31 2017-01-11 반더빌트유니버시티 폐의 용태에 따른 치료 방법
US9649467B2 (en) 2008-01-31 2017-05-16 Syk Technologies, Llc Nitric oxide reactor and distributor apparatus and method
US8501090B2 (en) * 2008-03-24 2013-08-06 Christian S. Minton Anti-microbial gas apparatus and method
US20100040703A1 (en) * 2008-08-13 2010-02-18 Chris Miller Use of nitric oxide
US10960168B2 (en) 2008-08-21 2021-03-30 Vero Biotech LLC Delivery of high concentration nitric oxide
US8607785B2 (en) 2008-08-21 2013-12-17 Geno Llc Systems and devices for generating nitric oxide
US10780241B2 (en) 2008-08-21 2020-09-22 Vero Biotech LLC Devices and methods for minimizing and treating high-altitude sickness
GB2463883A (en) * 2008-09-25 2010-03-31 Pharma Patents Ltd A pharmaceutical composition comprising an A-SMase inhibitor and an NO-donor
US9078992B2 (en) 2008-10-27 2015-07-14 Pursuit Vascular, Inc. Medical device for applying antimicrobial to proximal end of catheter
SG175979A1 (en) * 2009-05-15 2011-12-29 Recro Pharma Inc Sublingual dexmedetomidine compositions and methods of use thereof
CA2763111C (en) 2009-05-27 2019-09-24 Ino Therapeutics Llc Devices and methods for engaging indexed valve and pressurized canister assembly with collar and for linear actuation by plunger assembly into fluid communication with device for regulating drug delivery
EP2445508B1 (de) 2009-06-22 2018-11-14 VERO Biotech LLC Stickoxidtherapien
AU2009202685B1 (en) 2009-06-30 2010-08-19 Ino Therapeutics Llc Methods of treating term and near-term neonates having hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension
RU2420321C2 (ru) * 2009-08-11 2011-06-10 Анищенко Сергей Викторович Кислородная газожидкостная смесь (варианты)
CA2781295C (en) * 2009-11-20 2018-02-13 Geno Llc Nitric oxide delivery system
CA2797702C (en) 2010-04-26 2020-03-10 VERO Biotech LLC. Delivery of ultra pure nitric oxide (no)
DE102010016699A1 (de) 2010-04-29 2011-11-03 Maquet Gmbh & Co. Kg Verfahren und Vorrichtung zur Applikation mindestens eines medizinischen Gases an einen mit Hilfe eines Beatmungsgeräts beatmeten Patienten
US8685467B2 (en) 2010-08-03 2014-04-01 J. W. Randolph Miller Nitric oxide generation, dilution, and topical application apparatus and method
PL3479863T3 (pl) * 2010-09-10 2022-05-30 Mallinckrodt Pharmaceuticals Ireland Limited Kompozycje, sposoby i wyroby dotyczące farmaceutycznego tlenku azotu i układów kontrolowanego dostarczania go pacjentowi
WO2012037665A1 (en) 2010-09-24 2012-03-29 Oral Delivery Technology Ltd. Nitric oxide releasing amino acid ester for treatment of pulmonary hypertension and other respiratory conditions
JP2014501578A (ja) * 2010-12-03 2014-01-23 コーニンクレッカ フィリップス エヌ ヴェ 一酸化窒素の生成方法及び装置
DK2661300T3 (en) 2011-01-06 2018-01-15 Ino Therapeutics Llc Gas supply device and system
US12612370B2 (en) 2011-03-02 2026-04-28 Thermolife International, Llc Amino acid compositions
US10445846B2 (en) * 2011-04-14 2019-10-15 Elwha Llc Cost-effective resource apportionment technologies suitable for facilitating therapies
US10853819B2 (en) * 2011-04-14 2020-12-01 Elwha Llc Cost-effective resource apportionment technologies suitable for facilitating therapies
US10166381B2 (en) 2011-05-23 2019-01-01 Excelsior Medical Corporation Antiseptic cap
FR2976260B1 (fr) † 2011-06-09 2013-07-05 Air Liquide Procede de conditionnement de melanges no/n2 avec etapes de purge et rincage gazeux prealable
CA2841832C (en) 2011-07-12 2019-06-04 Icu Medical, Inc. Device for delivery of antimicrobial agent into a trans-dermal catheter
EP3650408A1 (de) 2011-10-03 2020-05-13 NitricGen, Inc. Vorrichtung und verfahren zur erzeugung von stickoxid in kontrollierten und genauen mengen
JP6389125B2 (ja) 2011-11-07 2018-09-12 ザ ジェネラル ホスピタル コーポレイション 赤血球の処理法
WO2013090278A2 (en) 2011-12-11 2013-06-20 Recro Pharma, Inc. Intranasal dexmedetomidine compositions and methods of use thereof
US20150272988A1 (en) 2012-03-07 2015-10-01 Advanced Inhalation Therapies (Ait) Ltd. Inhalation of nitric oxide for treating respiratory diseases
MX368858B (es) 2012-03-15 2019-10-18 Mallinckrodt Hospital Products Ip Ltd Metodos para administrar altas concentraciones de oxido nitrico.
FR2991025B1 (fr) 2012-05-24 2014-07-04 Air Liquide Sante Int Conditionnement d'un melange gazeux no/azote a haute concentration en no
FR2991026B1 (fr) 2012-05-24 2014-07-04 Air Liquide Sante Int Conditionnement a haute pression d'un melange gazeux no/azote
FR2990858B1 (fr) * 2012-05-24 2015-04-03 Air Liquide Sante Int Melange gazeux no/azote a teneur elevee en no pour traiter les detresses respiratoires hypoxemiantes severes
US9795756B2 (en) 2012-12-04 2017-10-24 Mallinckrodt Hospital Products IP Limited Cannula for minimizing dilution of dosing during nitric oxide delivery
TR201707036T4 (en) 2012-12-04 2018-11-21 Ino Therapeutics Llc Cannula to minimize dose dilution during administration of nitric oxide
JP6531990B2 (ja) 2013-02-28 2019-06-19 ユニバーシティ オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション 心肺血行動態を改善するための無機亜硝酸塩
EP2968827B1 (de) 2013-03-15 2019-02-20 The General Hospital Corporation Synthese von stickoxidgas zur inhalation
MX370385B (es) 2013-03-15 2019-12-11 Massachusetts Gen Hospital Sintesis inspiratoria de oxido nitrico.
US10517817B2 (en) 2013-05-09 2019-12-31 Syk Technologies, Llc Deep topical systemic nitric oxide therapy apparatus and method
WO2014210030A2 (en) 2013-06-25 2014-12-31 Ino Therapeutics Llc Methods of reducing the risk of mortality associated with a medical treatment
US9522247B2 (en) 2013-06-28 2016-12-20 L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude Method of treating a patient having pulmonary hypertension by long term NO therapy
US9517318B2 (en) 2013-06-28 2016-12-13 L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude Method of delivering medical gases via a nasal cannula assembly with flow control passage communicating with a deformable reservoir
US9492626B2 (en) 2013-06-28 2016-11-15 L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude Breathing assistance assemblies suitable for long term no therapy
US9522248B2 (en) 2013-06-28 2016-12-20 L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude Breathing assistance apparatus for delivery of nitric oxide to a patient by means of a nasal cannula assembly with flow control passage
US9486600B2 (en) 2013-06-28 2016-11-08 L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude Nasal cannula assembly with inhalation valves communicating with a deformable reservoir
US9566407B2 (en) 2013-06-28 2017-02-14 L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude Nasal cannula assembly with flow control passage communicating with a deformable reservoir
WO2015009615A1 (en) * 2013-07-15 2015-01-22 Vanderbilt University Methods for the production of collagen iv
FR3015000B1 (fr) 2013-12-12 2016-05-27 Air Liquide Sante (International) Systeme de stockage et de distribution de melanges no/azote
PL3104853T3 (pl) 2014-02-10 2020-05-18 Respivant Sciences Gmbh Leczenie stabilizatorami komórek tucznych zaburzeń ogólnoustrojowych
ES2792682T3 (es) 2014-02-10 2020-11-11 Respivant Sciences Gmbh Métodos para el tratamiento de enfermedades pulmonares con estabilizadores de mastocitos
EP3129092A4 (de) * 2014-04-09 2017-12-27 12th Man Technologies, Inc. Systeme und verfahren zur ausgabe von hochkonzentriertem stickoxid
US11225640B2 (en) 2014-04-15 2022-01-18 Aobiome Llc Ammonia oxidizing bacteria for treatment of psoriasis
KR20210100224A (ko) 2014-04-15 2021-08-13 에이오바이오미 엘엘씨 암모니아-산화 니트로소모나스 유트로파 균주 d23
EP2937089A1 (de) 2014-04-23 2015-10-28 Linde AG Vorrichtung zur Behandlung von, zur Behandlung von Komplikationen aufgrund von und/oder Vorbeugung von Atemwegserkrankungen
JP6546988B2 (ja) 2014-05-02 2019-07-17 エクセルシオール・メディカル・コーポレイションＥｘｃｅｌｓｉｏｒ Ｍｅｄｉｃａｌ Ｃｏｒｐｏｒａｔｉｏｎ 防腐キャップのためのストリップパッケージ
WO2016064928A1 (en) 2014-10-20 2016-04-28 Geno Llc Nitrogen dioxide storage cassette
ES2822215T3 (es) 2014-10-20 2021-04-29 Massachusetts Gen Hospital Sistemas y métodos de síntesis de óxido nítrico
AU2016243801B2 (en) 2015-04-02 2020-05-21 Hill-Rom Services Pte. Ltd. Manifold for respiratory device
DK3294404T3 (da) 2015-05-08 2025-09-08 Icu Medical Inc Medicinske konnektorer konfigureret til at modtage emittere af terapeutiske midler
US10238625B2 (en) 2015-08-07 2019-03-26 Respivant Sciences Gmbh Methods for the treatment of mast cell related disorders with mast cell stabilizers
WO2017027402A1 (en) 2015-08-07 2017-02-16 Patara Pharma, LLC Methods for the treatment of systemic disorders treatable with mast cell stabilizers, including mast cell related disorders
CA2997896C (en) * 2015-09-09 2026-03-17 Beyond Air Ltd Nitric oxide inhalation therapy for infants with bronchiolitis
CN113577468A (zh) 2015-10-01 2021-11-02 马林克罗特医疗产品知识产权公司 用于将高浓度no与吸入疗法气体一起扩散的装置和方法
US9744190B2 (en) 2016-01-15 2017-08-29 Thomas Tait Continuous gas generator
ES2968200T3 (es) 2016-01-27 2024-05-08 Syk Tech Llc Aparato y métodos de aplicación tópica de óxido nítrico
US10398820B2 (en) * 2016-02-12 2019-09-03 Mallinckrodt Hospital Products IP Limited Use and monitoring of inhaled nitric oxide with left ventricular assist devices
BR112018069582A2 (pt) 2016-03-25 2019-01-22 Massachusetts Gen Hospital sistemas e métodos de entrega para síntese elétrica de plasma de óxido nítrico
WO2018044942A1 (en) 2016-08-31 2018-03-08 Patara Pharma, LLC Cromolyn compositions for treatment of chronic cough due to idiopathic pulmonary fibrosis
EP3522983A4 (de) 2016-10-07 2020-06-03 Respivant Sciences GmbH Cromolynzusammensetzung zur behandlung von lungenfibrose
PL3525865T3 (pl) 2016-10-14 2023-02-06 Icu Medical, Inc. Nasadki dezynfekcyjne dla łączników medycznych
BR112019016708B1 (pt) 2017-02-27 2024-01-30 Third Pole, Inc Sistemas de geração de óxido nítrico
WO2018157175A1 (en) 2017-02-27 2018-08-30 Third Pole, Inc. Systems and methods for ambulatory generation of nitric oxide
MX2020010523A (es) 2017-02-27 2021-02-09 Third Pole Inc Sistemas y metodos para generar oxido nitrico.
WO2018183811A1 (en) 2017-03-31 2018-10-04 The General Hospital Corporation Systems and methods for a cooled nitric oxide generator
WO2018204206A2 (en) 2017-05-01 2018-11-08 Icu Medical, Inc. Medical fluid connectors and methods for providing additives in medical fluid lines
AU2018358349A1 (en) * 2017-11-02 2020-05-28 Beyond Air, Inc. Inhalation of nitric oxide
JP6618976B2 (ja) * 2017-11-14 2019-12-11 イノ セラピューティクス エルエルシー 指標付弁と襟部を有する加圧容器組立体を係合するため、かつ薬物送達を調整するための装置と流体連通したプランジャ組立体により直線的に作動させるための装置および方法
US20210386944A1 (en) * 2018-10-12 2021-12-16 Sanotize Research Development Corp. Gas-evolving compositions and container and delivery systems
US11541220B2 (en) 2018-11-07 2023-01-03 Icu Medical, Inc. Needleless connector with antimicrobial properties
US11541221B2 (en) 2018-11-07 2023-01-03 Icu Medical, Inc. Tubing set with antimicrobial properties
US11400195B2 (en) 2018-11-07 2022-08-02 Icu Medical, Inc. Peritoneal dialysis transfer set with antimicrobial properties
US11534595B2 (en) 2018-11-07 2022-12-27 Icu Medical, Inc. Device for delivering an antimicrobial composition into an infusion device
US11517732B2 (en) 2018-11-07 2022-12-06 Icu Medical, Inc. Syringe with antimicrobial properties
JP2022513096A (ja) 2018-11-21 2022-02-07 アイシーユー・メディカル・インコーポレーテッド リング及びインサートを有するキャップを備える抗菌装置
US12268709B2 (en) 2019-04-19 2025-04-08 National Institute For Materials Science Nitrogenous gas sustained releasing agent and nitrogenous gas sustained releaser composed of the same as well as nitrogenous gas sustained releasing method, respiratory equipment, package, and sustained releasing apparatus using the sustained releaser
CN114269685A (zh) 2019-05-15 2022-04-01 第三极股份有限公司 用于一氧化氮生成的电极
EP3969416A4 (de) 2019-05-15 2023-11-01 Third Pole, Inc. Systeme und vorrichtungen zur erzeugung von stickoxid
WO2020232414A1 (en) 2019-05-15 2020-11-19 Third Pole, Inc. Architectures for production of nitric oxide
FR3103110B1 (fr) 2019-11-15 2021-10-08 Air Liquide Dispositif de fourniture de gaz thérapeutique, en particulier de NO ou de N2O, à un patient
WO2021105900A1 (en) 2019-11-25 2021-06-03 Beyond Air, Inc. System and method for delivery of gas to a tissue
US11872367B2 (en) * 2020-01-02 2024-01-16 Becton, Dickinson And Company Antimicrobial and antithrombogenic gaseous release device and related systems and methods
EP4069069A4 (de) 2020-01-11 2024-07-03 Third Pole, Inc. Systeme und verfahren zur stickoxid-erzeugung mit feuchtigkeitsregelung
US12459820B2 (en) 2020-06-11 2025-11-04 J. W. Randolph Miller Stabilized and NO2-inhibited nitric oxide generating gels for inhaled nitric oxide therapy
EP4167920A4 (de) 2020-06-18 2024-06-12 Third Pole, Inc. Systeme und verfahren zur vorbeugung und behandlung von infektionen mit stickoxid
WO2022082072A1 (en) 2020-10-16 2022-04-21 Third Pole, Inc. Nitric oxide generation process controls
US11865139B2 (en) 2020-11-12 2024-01-09 Thermolife International, Llc Method of treating migraines and headaches
JP2024541338A (ja) * 2020-11-12 2024-11-08 サーモライフ インターナショナル， エルエルシー 血中酸素飽和度を増大させる方法
CA3204371A1 (en) 2020-12-07 2022-06-16 Icu Medical, Inc. Peritoneal dialysis caps, systems and methods
AU2022220004A1 (en) 2021-02-11 2023-08-17 Thermolife International, Llc A method of administering nitric oxide gas
EP4405019A4 (de) 2021-09-23 2025-07-16 Third Pole Inc Systeme und verfahren zur abgabe von stickoxid
FR3127408B1 (fr) 2021-09-29 2024-05-10 Inosystems Chariot hospitalier de transport de bouteille de gaz, notamment de NO médical
FR3131538B1 (fr) 2022-01-05 2025-01-17 Inosystems Dispositif de délivrance de NO avec système de dosage d’urgence
FR3137841B1 (fr) 2022-07-18 2024-06-14 Inosystems Dispositif de délivrance de NO avec système de dosage d’urgence
EP4209243B1 (de) 2022-01-05 2024-08-14 Inosystems No-ausgabevorrichtung mit notfalldosiersystem
FR3132025B1 (fr) 2022-01-24 2025-06-27 Inosystems Cartouche de stockage d’un mélange NO/azote et installation de fourniture de gaz associée
FR3133318B1 (fr) 2022-03-09 2024-03-22 Inosystems Dispositif de délivrance de NO avec circuit de secours à débit contrôlé
FR3133317B1 (fr) 2022-03-09 2024-03-01 Inosystems Appareil de délivrance de NO avec système de ventilation manuelle
FR3133316B1 (fr) 2022-03-09 2024-04-12 Inosystems Dispositif de délivrance de NO avec circuit de secours
FR3133315B1 (fr) 2022-03-09 2024-03-22 Inosystems Appareil de délivrance de NO à deux sorties de gaz
WO2023201363A2 (en) 2022-04-14 2023-10-19 Third Pole, Inc. Delivery of medicinal gas in a liquid medium
FR3136986B1 (fr) 2022-06-24 2024-06-14 Inosystems Affichage de la dose de NO par un dispositif de fourniture de NO en phase de pause
FR3138773B1 (fr) 2022-08-11 2024-08-02 Inosystems Installation de fourniture de gaz comprenant un ventilateur médical et un dispositif de délivrance de NO avec un système de dosage d’urgence
FR3145873A1 (fr) 2023-02-20 2024-08-23 Inosystems Appareil de fourniture de gaz, tel du NO, à un patient avec comptage du temps total de traitement effectif
FR3146810B1 (fr) 2023-03-21 2025-04-04 Inosystems Dispositif de calibration des capteurs d’un appareil de délivrance de NO
FR3148373B1 (fr) 2023-05-04 2025-12-19 Inosystems Appareil de délivrance de monoxyde d’azote gazeux en mode pulsé
FR3148527B1 (fr) 2023-05-12 2025-10-03 Inosystems Chariot hospitalier de transport de bouteille de gaz à sangles de fixation semi-rigides
FR3148723A1 (fr) 2023-05-16 2024-11-22 Inosystems Appareil de délivrance de NO à capteurs MOS à longue durée de vie
FR3150441A1 (fr) 2023-06-29 2025-01-03 Inosystems Affichage d’un rappel de maintenance sur un appareil de fourniture de monoxyde d’azote médical
FR3151765B1 (fr) 2023-08-02 2025-08-01 Inosystems Installation d’administration de NO gazeux comprenant un ventilateur médical à humidificateur intégré
FR3154010A1 (fr) 2023-10-11 2025-04-18 Inosystems Appareil de délivrance de NO comprenant une ligne d’analyse à pompe piézoélectrique
FR3154008A1 (fr) 2023-10-12 2025-04-18 Inosystems Alerte d’inversion de sens de connexion du capteur de débit d’une installation d’administration de monoxyde d’azote
FR3154009A1 (fr) 2023-10-12 2025-04-18 Inosystems Affichage d’une dose de NO préfixée sur un appareil de fourniture de gaz médical
FR3157812B1 (fr) 2024-01-03 2025-12-19 Inosystems Dispositif de délivrance de NO avec système de dosage d’urgence
FR3157813A1 (fr) 2024-01-03 2025-07-04 Inosystems Installation et méthode de titration de NO
FR3158448A1 (fr) 2024-01-19 2025-07-25 Inosystems Système de suivi à distance d’un appareil de fourniture de monoxyde d’azote
FR3159526A1 (fr) 2024-02-23 2025-08-29 Inosystems Installation de fourniture de NO pour fournir un débit de secours en cas de dysfonctionnement du capteur de débit
FR3160895A1 (fr) 2024-04-04 2025-10-10 Inosystems Appareil de fourniture de NO avec modification automatique des alarmes lors des changements de dose
FR3160894A1 (fr) 2024-04-04 2025-10-10 Inosystems Appareil de fourniture de NO avec fixation automatique des seuils d’alarme
FR3161571A1 (fr) 2024-04-24 2025-10-31 Inosystems Appareil de délivrance de NO alimenté par deux bouteilles de gaz
FR3162006A1 (fr) 2024-05-13 2025-11-14 Inosystems Appareil de fourniture de NO adapté au transport terrestre ou aérien
FR3164394A1 (fr) 2024-07-09 2026-01-16 Inosystems Installation de fourniture de NO comprenant un appareil de délivrance de NO et un ventilateur d’anesthésie

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3367332A (en) * 1965-08-27 1968-02-06 Gen Electric Product and process for establishing a sterile area of skin
US3785377A (en) * 1970-11-12 1974-01-15 S Jorgensen Plant, preferably for anaesthesia
US3745991A (en) * 1971-02-22 1973-07-17 Champion Spark Plug Co Environmental contamination control device
US4010897A (en) * 1976-03-31 1977-03-08 Charles F. Kettering Foundation Method and apparatus for home production and application of nitrogen fertilizer
IL57239A (en) * 1979-05-08 1982-04-30 Alamaro Moshe Production of nitric oxides
US4297123A (en) * 1980-02-07 1981-10-27 Wyse Harold G Method and apparatus for producing a nitrate fertilizer
US4336798A (en) * 1980-10-06 1982-06-29 Anthony V. Beran Medical corrugated respiratory tube
SE438261B (sv) * 1981-07-08 1985-04-15 Draco Ab Anvendning i dosinhalator av ett perforerat membran
US4484577A (en) * 1981-07-23 1984-11-27 Key Pharmaceuticals, Inc. Drug delivery method and inhalation device therefor
US4534343A (en) * 1984-01-27 1985-08-13 Trutek Research, Inc. Metered dose inhaler
US4592348A (en) * 1984-12-17 1986-06-03 Waters Iv William C Aerosol inhaler
US4675174A (en) * 1985-08-16 1987-06-23 Alza Corporation Veterinary dispenser delivering beneficial agent by gas power generated in situ
US4852561A (en) * 1988-07-27 1989-08-01 Sperry C R Inhalation device
US4877589A (en) * 1988-09-19 1989-10-31 Hare Louis R O Nitrogen fixation by electric arc and catalyst
US4915915A (en) * 1988-10-11 1990-04-10 Treharne Richard W Water-powdered piezoelectric unit for producing nitrogen fertilizer
US4954526A (en) * 1989-02-28 1990-09-04 The United States Of America As Represented By The Department Of Health And Human Services Stabilized nitric oxide - primary amine complexes useful as cardiovascular agents
US5208233A (en) * 1989-09-15 1993-05-04 The United States Of America As Represented By The Department Of Health And Human Services Anti-hypertensive compositions of secondary amine-nitric oxide adducts and use thereof
US5007419A (en) * 1989-09-25 1991-04-16 Allan Weinstein Inhaler device
US5178138A (en) * 1990-09-11 1993-01-12 Walstrom Dennis R Drug delivery device
US5155137A (en) * 1990-09-20 1992-10-13 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Complexes of nitric oxide with polyamines
US5187305A (en) * 1990-11-26 1993-02-16 Glaxo Inc. S-nitroso-N-alkonoylpenicillamines
EP1875917A3 (de) 1990-12-05 2012-11-28 The General Hospital Corporation Gasmischung zur Behandlung von Lungengefässverengung
US5396882A (en) * 1992-03-11 1995-03-14 The General Hospital Corporation Generation of nitric oxide from air for medical uses
IL101406A (en) * 1991-03-29 1998-02-08 Brigham & Womens Hospital Pharmaceutical compositions containing s-nitrosothiol derivatives
US5385937A (en) * 1991-04-10 1995-01-31 Brigham & Women's Hospital Nitrosation of homocysteine as a method for treating homocysteinemia
WO1993012068A1 (en) * 1991-12-11 1993-06-24 Brigham And Women's Hospital S-nitrosothiols as smooth muscle relaxants and therapeutic uses thereof
US5427797A (en) * 1993-04-06 1995-06-27 Brigham And Women's Hospital Systemic effects of nitric oxide inhalation

Also Published As

Publication number Publication date
HK1020686A1 (en) 2003-06-19
DK0786264T3 (da) 2008-03-10
GR960300032T1 (en) 1996-06-30
EP0786264A2 (de) 1997-07-30
ES2288660T5 (es) 2015-05-29
DE122008000012I1 (de) 2008-08-14
EE03119B1 (et) 1998-10-15
DK0560928T3 (da) 1997-12-01
EP0786264A3 (de) 1997-08-13
EP1875917A2 (de) 2008-01-09
DE69133575D1 (de) 2007-09-06
DE69133584D1 (de) 2007-12-13
SG47527A1 (en) 1998-04-17
DK1516639T3 (da) 2007-11-26
DE69127756D1 (de) 1997-10-30
ES2132043T3 (es) 2008-04-01
EP0560928A1 (de) 1993-09-22
EP0560928B1 (de) 1997-09-24
LU90886I2 (fr) 2002-03-25
JPH10158175A (ja) 1998-06-16
NL300081I1 (nl) 2002-04-02
DE69127756T2 (de) 1998-02-05
EP1516639A1 (de) 2005-03-23
NL300081I2 (nl) 2002-06-03
LU91423I2 (fr) 2008-06-30
LU91404I2 (fr) 2008-02-21
CA2097823A1 (en) 1992-06-06
ES2082732T3 (es) 1997-12-16
ES2132043T1 (es) 1999-08-16
NL300342I1 (nl) 2008-06-02
GR3024865T3 (en) 1998-01-30
LV12201B (en) 1999-05-20
DE10299002I1 (de) 2012-07-05
DE69133584T4 (de) 2009-11-19
AU657726B2 (en) 1995-03-23
CA2097823C (en) 1999-06-29
ATE367842T2 (de) 2007-08-15
NL300327I1 (nl) 2008-03-03
WO1992010228A1 (en) 1992-06-25
DE122008000012I2 (de) 2012-04-12
DK1516639T4 (en) 2015-06-29
HK1010101A1 (en) 1999-06-11
EP1516639B2 (de) 2015-04-15
ES2082732T1 (es) 1996-04-01
NL300327I2 (nl) 2008-04-01
DE122007000103I1 (de) 2008-04-03
ATE158509T1 (de) 1997-10-15
EP1875917A3 (de) 2012-11-28
HK1076407A1 (en) 2006-01-20
EP0560928A4 (en) 1993-12-01
JP2701978B2 (ja) 1998-01-21
JP3718491B2 (ja) 2005-11-24
JP2003111845A (ja) 2003-04-15
LV12201A (lv) 1999-01-20
JPH06504778A (ja) 1994-06-02
EP0786264B1 (de) 2007-10-31
GR990300018T1 (en) 1999-06-30
US5485827A (en) 1996-01-23
DE69133575T2 (de) 2008-04-17
US5873359A (en) 1999-02-23
DE786264T1 (de) 2000-11-02
JP3510755B2 (ja) 2004-03-29
ES2288660T3 (es) 2008-01-16
AU9149891A (en) 1992-07-08
DE560928T1 (de) 1994-09-22
EP1516639B1 (de) 2007-07-25
DE69133584T2 (de) 2008-08-21

Similar Documents

Publication Publication Date Title
ATE376850T1 (de) Vorrichtung zum behandeln einen lungengefässverengung und von asthma
IL113448A0 (en) Pharmaceutical composition containing an organic nitric oxide donor
ATE67328T1 (de) Authentifizierungsgeraet.
ATE84434T1 (de) Einrichtung zur behandlung von gasen.
BR9204815A (pt) Compsoicaos farmaceutica a base de taurina para a administracao por inalacao,e,processo de utilizacao
Eisenbud et al. Trace metals in urban aerosols
JPS5218468A (en) Process for removal of nitrogen oxides
ATE92672T1 (de) Parametrisch geaendertes supraleitendes material.
FR2547162B1 (fr) Procede et dispositif pour l'enrichissement de l'atmosphere des serres avec du dioxyde de carbone pur
Winnick Combined SOx, NOx removal and concentration from flue gas through an electrochemical membrane. Quarterly progress report, January 1-March 31, 1989
JPS51119672A (en) Denitrating method
JPS51136575A (en) Process for simultaneous removal of nitrogen oxides and sulfur oxides in exhaust gas
ITRM910617A1 (it) Apparecchio per la lettura dell'ossigeno o di altro componente gassoso nell'aria, in particolare per il rilevamento dell'inquinamento.
IT7841641A0 (it) Dispositivo per l'introduzione di particelle in un analizzatore del contenuto di polvere in un ambiente gassoso.
JPS51149867A (en) A composition for purification of gases
FR999548A (fr) Procédé et dispositif d'enrichissement ou de récupération des éléments gazeux adsorbables