ATE377022T1 - Isolierte decapeptide, die an hla moleküle binden,sowie deren verwendung - Google Patents

Isolierte decapeptide, die an hla moleküle binden,sowie deren verwendung

Info

Publication number
ATE377022T1
ATE377022T1 AT98930433T AT98930433T ATE377022T1 AT E377022 T1 ATE377022 T1 AT E377022T1 AT 98930433 T AT98930433 T AT 98930433T AT 98930433 T AT98930433 T AT 98930433T AT E377022 T1 ATE377022 T1 AT E377022T1
Authority
AT
Austria
Prior art keywords
decapeptides
bind
isolated
hla molecules
hla
Prior art date
Application number
AT98930433T
Other languages
English (en)
Inventor
Danila Valmori
Jean-Charles Cerottini
Pedro Romero
Original Assignee
Ludwig Inst Cancer Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/880,963 external-priority patent/US6025470A/en
Application filed by Ludwig Inst Cancer Res filed Critical Ludwig Inst Cancer Res
Application granted granted Critical
Publication of ATE377022T1 publication Critical patent/ATE377022T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT98930433T 1997-06-23 1998-06-18 Isolierte decapeptide, die an hla moleküle binden,sowie deren verwendung ATE377022T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/880,963 US6025470A (en) 1997-06-23 1997-06-23 Isolated nona- and decapeptides which bind to HLA molecules, and the use thereof
US09/061,388 US6277956B1 (en) 1997-06-23 1998-04-16 Isolated nona- and decapeptides which bind to HLA molecules, and the use thereof

Publications (1)

Publication Number Publication Date
ATE377022T1 true ATE377022T1 (de) 2007-11-15

Family

ID=26741014

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98930433T ATE377022T1 (de) 1997-06-23 1998-06-18 Isolierte decapeptide, die an hla moleküle binden,sowie deren verwendung

Country Status (8)

Country Link
US (3) US6326200B1 (de)
EP (1) EP1012173B1 (de)
CN (1) CN1313481C (de)
AT (1) ATE377022T1 (de)
AU (1) AU732468B2 (de)
CA (1) CA2295321C (de)
NZ (1) NZ501752A (de)
WO (1) WO1998058951A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998058951A1 (en) * 1997-06-23 1998-12-30 Ludwig Institute For Cancer Research Isolated nona- and decapeptides which bind to hla molecules, and the use thereof
WO2001016320A1 (en) * 1999-08-30 2001-03-08 Ludwig Institute For Cancer Research Isolated nona and decapeptides which bind to hla molecules, and the use thereof
CA2721011A1 (en) 1999-10-22 2001-05-03 Aventis Pasteur Limited Modified gp100 and uses thereof
AU2001229681A1 (en) * 2000-01-20 2001-07-31 Ludwig Institute For Cancer Research Mage antigenic peptides which bind hla-b35 and hla-b44
FR2806727A1 (fr) * 2000-03-23 2001-09-28 Pf Medicament Molecule d'interet pharmaceutique comprotant en son extremite n-terminale un acide glutamique ou une glutamine sous forme de sel d'addition d'acide fort physiologiquement acceptable
EP1425040A2 (de) * 2001-09-14 2004-06-09 Cytos Biotechnology AG Steigerung der durch virusähnliche partikel hervorgerufenen immunantwort durch in-vivo aktivierung von antigen-präsentierenden zellen
AU2002339224B2 (en) 2001-09-14 2008-10-09 Kuros Us Llc Packaging of immunostimulatory substances into virus-like particles: method of preparation and use
AU2003242742B2 (en) * 2002-06-20 2009-04-30 Cytos Biotechnology Ag Packaged virus-like particles for use as adjuvants: method of preparation and use
EP1575994B1 (de) 2002-09-27 2013-01-09 Ludwig Institute for Cancer Research Ltd. Mage-c2-antigene peptide und deren verwendungen
US7537767B2 (en) 2003-03-26 2009-05-26 Cytis Biotechnology Ag Melan-A- carrier conjugates
US20060210588A1 (en) * 2003-03-26 2006-09-21 Cytos Biotechnology Ag Hiv-peptide-carrier-conjugates
AU2004223736B2 (en) * 2003-03-26 2010-05-27 Cytos Biotechnology Ag Melan-A peptide analogue-virus-like-particle conjugates
KR101304243B1 (ko) * 2005-08-09 2013-09-05 온코세라피 사이언스 가부시키가이샤 ＨＬＡ-Ａ2 양성 환자용 글리피칸-3(ｇｌｙｐｉｃａｎ-3)유래의 암 거절항원 펩티드 및 그를 포함하는 의약
JP5484732B2 (ja) * 2005-12-14 2014-05-07 サイトス バイオテクノロジー アーゲー 過敏症の治療のための免疫賦活性核酸パッケージ粒子
WO2007144150A1 (en) 2006-06-12 2007-12-21 Cytos Biotechnology Ag Processes for packaging oligonucleotides into virus-like particles of rna bacteriophages
WO2018094570A1 (zh) * 2016-11-22 2018-05-31 深圳华大基因研究院 多肽及其应用
WO2018094569A1 (zh) * 2016-11-22 2018-05-31 深圳华大基因研究院 多肽及其应用
CN110167956B (zh) * 2016-11-30 2023-04-07 深圳华大生命科学研究院 多肽及其应用
WO2024216241A2 (en) * 2023-04-14 2024-10-17 The Johns Hopkins University Heteroclitic neoepitope vaccines

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5662907A (en) * 1992-08-07 1997-09-02 Cytel Corporation Induction of anti-tumor cytotoxic T lymphocytes in humans using synthetic peptide epitopes
US5487974A (en) * 1992-12-22 1996-01-30 Ludwig Institute For Cancer-Research Method for detecting complexes containing human leukocyte antigen A2 (HLA-A2) molecules and a tyrosinase drived peptide on abnormal cells
US5554506A (en) 1994-03-24 1996-09-10 Ludwig Institute For Cancer Research Isolated, MAGE-3 derived peptides which complex with HLA-A2 molecules and uses thereof
US5851523A (en) * 1994-03-24 1998-12-22 Ludwig Institute For Cancer Research. Isolated, peptides derived from MAGE tumor rejection antigen precursors which complex with HLA-A2 molecules and uses thereof
US5554724A (en) 1994-03-24 1996-09-10 University Of Leiden Isolated tumor rejection antigen precursor MAGE-2 derived peptides, and uses thereof
WO1995029193A2 (en) * 1994-04-22 1995-11-02 The Government Of The United States Of America Represented By The Secretary, Department Of Health And Human Services Melanoma antigens
US5874560A (en) * 1994-04-22 1999-02-23 The United States Of America As Represented By The Department Of Health And Human Services Melanoma antigens and their use in diagnostic and therapeutic methods
ES2205209T3 (es) * 1996-04-26 2004-05-01 Rijksuniversiteit Te Leiden Procedimientos de seleccion y de produccion de epitopos peptidicos de linfocitos t y vacunas que contienen los indicados epitopos seleccionados.
ZA975858B (en) * 1996-07-11 1998-09-01 Akzo Nobel Nv Melanoma associated peptide analogues and vaccines against melanoma
US6025470A (en) * 1997-06-23 2000-02-15 Ludwig Institute For Cancer Research Isolated nona- and decapeptides which bind to HLA molecules, and the use thereof
WO1998058951A1 (en) * 1997-06-23 1998-12-30 Ludwig Institute For Cancer Research Isolated nona- and decapeptides which bind to hla molecules, and the use thereof

Also Published As

Publication number Publication date
CA2295321A1 (en) 1998-12-30
AU732468B2 (en) 2001-04-26
EP1012173B1 (de) 2007-10-31
CA2295321C (en) 2008-01-29
CN1313481C (zh) 2007-05-02
WO1998058951A1 (en) 1998-12-30
EP1012173A4 (de) 2000-07-05
US20030082804A1 (en) 2003-05-01
US20040152193A1 (en) 2004-08-05
HK1028615A1 (en) 2001-02-23
CN1261374A (zh) 2000-07-26
US7713714B2 (en) 2010-05-11
US7344879B2 (en) 2008-03-18
US6326200B1 (en) 2001-12-04
NZ501752A (en) 2000-12-22
EP1012173A1 (de) 2000-06-28
AU7982798A (en) 1999-01-04

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