ATE377649T1 - Verfahren und zelle zur expression von rekombinanten proteinprodukten - Google Patents

Verfahren und zelle zur expression von rekombinanten proteinprodukten

Info

Publication number: ATE377649T1
Authority: AT; Austria
Prior art keywords: promoter; recombinant protein; protein products; inducible promoter; cell
Prior art date: 2000-03-24

Application number

AT01922467T

Other languages

English (en)

Inventor

Marc Better

Original Assignee

Xoma Technology Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-03-24

Filing date

2001-03-19

Publication date

2007-11-15

2001-03-19 Application filed by Xoma Technology Ltd filed Critical Xoma Technology Ltd

2007-11-15 Application granted granted Critical

2007-11-15 Publication of ATE377649T1 publication Critical patent/ATE377649T1/de

Links

102000007056 Recombinant Fusion Proteins Human genes 0.000 title abstract 2
108010008281 Recombinant Fusion Proteins Proteins 0.000 title abstract 2
230000001939 inductive effect Effects 0.000 abstract 4
230000009056 active transport Effects 0.000 abstract 2
230000001580 bacterial effect Effects 0.000 abstract 2
230000002950 deficient Effects 0.000 abstract 2
239000000411 inducer Substances 0.000 abstract 2
230000022532 regulation of transcription, DNA-dependent Effects 0.000 abstract 2
PYMYPHUHKUWMLA-WDCZJNDASA-N arabinose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)C=O PYMYPHUHKUWMLA-WDCZJNDASA-N 0.000 abstract 1
PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 abstract 1
SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 abstract 1
239000013604 expression vector Substances 0.000 abstract 1
229920001184 polypeptide Polymers 0.000 abstract 1
102000004196 processed proteins & peptides Human genes 0.000 abstract 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/635—Externally inducible repressor mediated regulation of gene expression, e.g. tetR inducible by tetracyline
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Microbiology (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Plant Pathology (AREA)
Biophysics (AREA)
Physics & Mathematics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

AT01922467T 2000-03-24 2001-03-19 Verfahren und zelle zur expression von rekombinanten proteinprodukten ATE377649T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US19212900P	2000-03-24	2000-03-24
US19223800P	2000-03-27	2000-03-27

Publications (1)

Publication Number	Publication Date
ATE377649T1 true ATE377649T1 (de)	2007-11-15

Family

ID=26887762

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01922467T ATE377649T1 (de)	2000-03-24	2001-03-19	Verfahren und zelle zur expression von rekombinanten proteinprodukten

Country Status (12)

Country	Link
US (2)	US6803210B2 (de)
EP (1)	EP1268823B1 (de)
JP (1)	JP2003528616A (de)
AT (1)	ATE377649T1 (de)
AU (2)	AU2001249265B2 (de)
CA (1)	CA2404046C (de)
CY (1)	CY1107173T1 (de)
DE (1)	DE60131261T2 (de)
DK (1)	DK1268823T3 (de)
ES (1)	ES2295151T3 (de)
PT (1)	PT1268823E (de)
WO (1)	WO2001073082A2 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7754211B2 (en) *	1992-04-10	2010-07-13	Research Development Foundation	Immunotoxins directed against c-erbB-2(HER-2/neu) related surface antigens
ES2288630T3 (es)	2002-12-02	2008-01-16	Basf Aktiengesellschaft	Sistema de expresion, que puede ser inducido por medio de la l-ramnosa.
FI116068B (fi) *	2003-09-15	2005-09-15	Fit Biotech Oyj Plc	Uusi selektiojärjestelmä, siinä käyttökelpoinen vektori, bakteerisolukantoja sekä menetelmä solujen valikoimiseksi
GB0325494D0 (en) *	2003-10-31	2003-12-03	Sbl Vaccin Ab	Expression system
US20060078952A1 (en) *	2004-09-14	2006-04-13	Carine Robichon	Method for identifying antimicrobial molecules which interfere with apolipoprotein N-acyltransferase activity
US7846712B2 (en)	2006-06-01	2010-12-07	Alliance For Sustainable Energy, Llc	L-arabinose fermenting yeast
WO2007143247A2 (en) *	2006-06-02	2007-12-13	Midwest Research Institute	Cloning and characterization of l-arabinose transporters from non-conventional yeast
EP2356240A2 (de) *	2008-11-18	2011-08-17	USV Limited	Neues synthetisches expressionsvehikel
WO2012117963A1 (ja) *	2011-02-28	2012-09-07	協和発酵キリン株式会社	有用タンパク質の発現を厳密に制御できる微生物
AU2013299910B2 (en)	2012-08-05	2019-01-24	Absci Corporation	Inducible coexpression system
US12157766B2 (en) *	2012-08-05	2024-12-03	Absci Corporation	Cytoplasmic expression system
EP3574092A4 (de)	2017-01-30	2021-01-13	Intrexon Corporation	Molekulare schalter
ES3026707T3 (en) *	2019-08-05	2025-06-12	Wacker Chemie Ag	Bacterial strain for releasing a recombinant protein in a fermentation method

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS61501186A (ja)	1983-10-11	1986-06-19	インターナシヨナル　ジネテイツク　エンジニアリング　インコーポレイテツド	タウマチン（Ｔｈａｕｍａｔｉｎ）遺伝子の作製と発現
US5028530A (en)	1985-01-28	1991-07-02	Xoma Corporation	AraB promoters and method of producing polypeptides, including cecropins, by microbiological techniques

2001
- 2001-03-19 JP JP2001570798A patent/JP2003528616A/ja active Pending
- 2001-03-19 WO PCT/US2001/008754 patent/WO2001073082A2/en not_active Ceased
- 2001-03-19 AT AT01922467T patent/ATE377649T1/de active
- 2001-03-19 US US09/811,933 patent/US6803210B2/en not_active Expired - Lifetime
- 2001-03-19 CA CA002404046A patent/CA2404046C/en not_active Expired - Fee Related
- 2001-03-19 ES ES01922467T patent/ES2295151T3/es not_active Expired - Lifetime
- 2001-03-19 PT PT01922467T patent/PT1268823E/pt unknown
- 2001-03-19 DK DK01922467T patent/DK1268823T3/da active
- 2001-03-19 AU AU2001249265A patent/AU2001249265B2/en not_active Ceased
- 2001-03-19 DE DE60131261T patent/DE60131261T2/de not_active Expired - Lifetime
- 2001-03-19 EP EP01922467A patent/EP1268823B1/de not_active Expired - Lifetime
- 2001-03-19 AU AU4926501A patent/AU4926501A/xx active Pending
2004
- 2004-10-12 US US10/963,414 patent/US20050260705A1/en not_active Abandoned
2008
- 2008-02-01 CY CY20081100124T patent/CY1107173T1/el unknown

Also Published As

Publication number	Publication date
PT1268823E (pt)	2008-02-01
ES2295151T3 (es)	2008-04-16
DE60131261D1 (de)	2007-12-20
WO2001073082A2 (en)	2001-10-04
DE60131261T2 (de)	2008-09-04
WO2001073082A3 (en)	2002-02-14
EP1268823B1 (de)	2007-11-07
JP2003528616A (ja)	2003-09-30
AU2001249265B2 (en)	2006-10-26
DK1268823T3 (da)	2008-03-10
US20050260705A1 (en)	2005-11-24
US6803210B2 (en)	2004-10-12
EP1268823A2 (de)	2003-01-02
CY1107173T1 (el)	2012-10-24
CA2404046A1 (en)	2001-10-04
AU4926501A (en)	2001-10-08
CA2404046C (en)	2008-06-03
US20020037552A1 (en)	2002-03-28

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2008-05-15

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