ATE256747T1 - Glykosyltransferase expression in aspergillus - Google Patents

Glykosyltransferase expression in aspergillus

Info

Publication number
ATE256747T1
ATE256747T1 AT96920281T AT96920281T ATE256747T1 AT E256747 T1 ATE256747 T1 AT E256747T1 AT 96920281 T AT96920281 T AT 96920281T AT 96920281 T AT96920281 T AT 96920281T AT E256747 T1 ATE256747 T1 AT E256747T1
Authority
AT
Austria
Prior art keywords
aspergillus
expression
polypeptides
secretion
result
Prior art date
Application number
AT96920281T
Other languages
English (en)
Inventor
Katherine H Kadoma
Michael Ward
Original Assignee
Genencor Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genencor Int filed Critical Genencor Int
Application granted granted Critical
Publication of ATE256747T1 publication Critical patent/ATE256747T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT96920281T 1995-05-18 1996-05-16 Glykosyltransferase expression in aspergillus ATE256747T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44395495A 1995-05-18 1995-05-18
PCT/US1996/007171 WO1996036718A1 (en) 1995-05-18 1996-05-16 Expression of glycosyltransferase in aspergillus

Publications (1)

Publication Number Publication Date
ATE256747T1 true ATE256747T1 (de) 2004-01-15

Family

ID=23762876

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96920281T ATE256747T1 (de) 1995-05-18 1996-05-16 Glykosyltransferase expression in aspergillus

Country Status (7)

Country Link
US (1) US20050164351A1 (de)
EP (1) EP0826054B1 (de)
AT (1) ATE256747T1 (de)
CA (1) CA2221271A1 (de)
DE (1) DE69631127T2 (de)
DK (1) DK0826054T3 (de)
WO (1) WO1996036718A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6265204B1 (en) * 1997-01-17 2001-07-24 Genencor International, Inc. DNA sequences, vectors, and fusion polypeptides for secretion of polypeptides in filamentous fungi
ES2143408B1 (es) * 1998-04-02 2000-12-01 Urquima Sa Promotor y construcciones para expresion de proteinas recombinantes en hongos filamentosos.
EP1334182B2 (de) 2000-11-06 2021-03-24 Chr. Hansen A/S Verfahren zur herstellung von nicht aus dem rind stammendem chymosin und dessen anwendung
CA2485102A1 (en) * 2002-05-03 2003-11-13 Neose Technologies, Inc. Recombinant glycosyltransferase fusion proteins
US20110104750A1 (en) * 2006-04-05 2011-05-05 Michael Ward Filamentous Fungi Having Reduced UDP-Galactofuranose Content
US20090253173A1 (en) * 2008-04-08 2009-10-08 Danisco Us Inc., Genencor Division Filamentous fungi with inactivated protease genes for altered protein production
WO2013174927A1 (en) * 2012-05-23 2013-11-28 Novartis International Pharmaceutical Limited Production of fucosylated glycoproteins
SG11201700446XA (en) 2014-07-21 2017-02-27 Glykos Finland Oy Production of glycoproteins with mammalian-like n-glycans in filamentous fungi

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4751180A (en) * 1985-03-28 1988-06-14 Chiron Corporation Expression using fused genes providing for protein product
DE3650783T2 (de) * 1985-04-15 2004-07-15 Dsm Ip Assets B.V. Verwendung des Glucoamylasepromotors aus Apergillus
US5679543A (en) * 1985-08-29 1997-10-21 Genencor International, Inc. DNA sequences, vectors and fusion polypeptides to increase secretion of desired polypeptides from filamentous fungi
DE69032616T2 (de) * 1989-06-16 1999-03-11 Genencor International, Inc., Rochester, N.Y. Dna-sequenzen, vektoren und fusionspolypeptide zur erhöhung der sekretion gewünschter polypeptide von filamentösen fungi
US5324663A (en) * 1990-02-14 1994-06-28 The Regents Of The University Of Michigan Methods and products for the synthesis of oligosaccharide structures on glycoproteins, glycolipids, or as free molecules, and for the isolation of cloned genetic sequences that determine these structures
DE4244915C2 (de) * 1992-08-14 1998-12-03 Widmar Prof Dr Tanner DNA-Moleküle codierend Proteine, die an der O-Glykosylierung von Proteinen beteiligt sind
EP0702721B1 (de) * 1993-06-09 2001-01-03 Unilever N.V. Verfahren zur herstellung von fusionsproteinen, die scfv fragmente enthalten, in transformierten schimmelpilzen

Also Published As

Publication number Publication date
DK0826054T3 (da) 2004-04-19
EP0826054B1 (de) 2003-12-17
WO1996036718A1 (en) 1996-11-21
EP0826054A1 (de) 1998-03-04
US20050164351A1 (en) 2005-07-28
DE69631127T2 (de) 2004-07-08
CA2221271A1 (en) 1996-11-21
DE69631127D1 (en) 2004-01-29

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties