ATE378364T1 - Polyamhydride mit therapeutisch verwendbaren abbauprodukten - Google Patents

Polyamhydride mit therapeutisch verwendbaren abbauprodukten

Info

Publication number: ATE378364T1
Authority: AT; Austria
Prior art keywords: ortho; aromatic; substituted; dicarboxylic acid; well
Prior art date: 1997-09-10

Application number

AT98946004T

Other languages

English (en)

Inventor

Kathryn Uhrich

Original Assignee

Univ Rutgers

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-09-10

Filing date

1998-09-10

Publication date

2007-11-15

1998-09-10 Application filed by Univ Rutgers filed Critical Univ Rutgers

2007-11-15 Application granted granted Critical

2007-11-15 Publication of ATE378364T1 publication Critical patent/ATE378364T1/de

Links

230000001225 therapeutic effect Effects 0.000 title abstract 2
239000007857 degradation product Substances 0.000 title 1
OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 abstract 2
229920005578 aromatic polyanhydride Polymers 0.000 abstract 2
150000008064 anhydrides Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
238000012377 drug delivery Methods 0.000 abstract 1
239000007943 implant Substances 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000000178 monomer Substances 0.000 abstract 1
239000006186 oral dosage form Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G67/00—Macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing oxygen or oxygen and carbon, not provided for in groups C08G2/00 - C08G65/00
- C08G67/04—Polyanhydrides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L67/00—Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Polymers & Plastics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Pharmacology & Pharmacy (AREA)
Oral & Maxillofacial Surgery (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Dermatology (AREA)
Engineering & Computer Science (AREA)
Transplantation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Polyesters Or Polycarbonates (AREA)
Materials For Medical Uses (AREA)
Medicinal Preparation (AREA)
Polyethers (AREA)

AT98946004T 1997-09-10 1998-09-10 Polyamhydride mit therapeutisch verwendbaren abbauprodukten ATE378364T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US5832897P	1997-09-10	1997-09-10

Publications (1)

Publication Number	Publication Date
ATE378364T1 true ATE378364T1 (de)	2007-11-15

Family

ID=22016145

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT98946004T ATE378364T1 (de)	1997-09-10	1998-09-10	Polyamhydride mit therapeutisch verwendbaren abbauprodukten

Country Status (13)

Country	Link
EP (1)	EP1032605B1 (de)
JP (2)	JP4130305B2 (de)
KR (1)	KR20010023852A (de)
CN (1)	CN1158325C (de)
AT (1)	ATE378364T1 (de)
AU (1)	AU750424C (de)
CA (1)	CA2302508C (de)
CY (1)	CY1107857T1 (de)
DE (1)	DE69838731T2 (de)
DK (1)	DK1032605T3 (de)
ES (1)	ES2296344T3 (de)
PT (1)	PT1032605E (de)
WO (1)	WO1999012990A1 (de)

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US7122615B1 (en)	1998-09-10	2006-10-17	Rutgers, The State University Of New Jersey	Polyanhydrides with therapeutically useful degradation products
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US6685928B2 (en) *	1999-12-07	2004-02-03	Rutgers, The State University Of New Jersey	Therapeutic compositions and methods
ATE444086T1 (de)	1999-12-07	2009-10-15	Univ Rutgers	Therapeutische zusammensetzungen und verfahren zur behandlung von periodontitis mit entzündunshemmenden mitteln
US20040038948A1 (en)	1999-12-07	2004-02-26	Uhrich Kathryn E.	Therapeutic compositions and methods
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EP2146701B1 (de)	2007-04-12	2013-10-16	Rutgers, The State University of New Jersey	Biologisch abbaubare polyanhydride mit natürlichen bioaktiven molekülen
US8217134B2 (en)	2007-08-30	2012-07-10	Bezwada Biomedical, Llc	Controlled release of biologically active compounds
US8048980B2 (en)	2007-09-17	2011-11-01	Bezwada Biomedical, Llc	Hydrolysable linkers and cross-linkers for absorbable polymers
CN101357244B (zh) *	2008-09-18	2011-06-01	复旦大学附属肿瘤医院	纳米粒子增强的光固化聚酸酐载药聚合物支架的制备方法
EP2569015A1 (de)	2010-05-14	2013-03-20	Iberhospitex S.A.	Verbindungen zur synthese von biostabilen polyurethan-, polyharnstoff- oder polyharnstoffurethanpolymeren
US20140030341A1 (en) *	2011-04-06	2014-01-30	Rutgers, The State University Of New Jersey	Polymers and methods for the treatment of pain
AU2013232297B2 (en) *	2012-03-16	2016-01-14	The Johns Hopkins University	Controlled release formulations for the delivery of HIF-1 inhibitors
EP2825207B1 (de) *	2012-03-16	2020-08-19	The Johns Hopkins University	Nichtlineare multiblock-copolymer-arzneimittelkonjugate zur verabreichung von wirkstoffen
US9144579B2 (en)	2012-08-17	2015-09-29	Rutgers, The State University Of New Jersey	Polyesters and methods of use thereof
US20140120057A1 (en)	2012-10-25	2014-05-01	Rutgers, The State University Of New Jersey	Polymers and methods thereof for wound healing
CN103910875B (zh) *	2012-12-31	2017-06-13	张雅珍	蒽环类抗生素偶联非线性多嵌段共聚物及其制备方法和应用
US9387250B2 (en)	2013-03-15	2016-07-12	Rutgers, The State University Of New Jersey	Therapeutic compositions for bone repair
WO2014194055A1 (en)	2013-05-29	2014-12-04	Rutgers, The State University Of New Jersey	Antioxidant-based poly(anhydride-esters)
US10023521B2 (en)	2014-06-13	2018-07-17	Rutgers, The State University Of New Jersey	Process and intermediates for preparing poly(anhydride-esters)
WO2016097848A1 (en)	2014-12-18	2016-06-23	Dexcel Pharma Technologies Ltd.	Alternating and semi-alternating poly(ester-anhydride) copolymers
WO2016164898A1 (en)	2015-04-10	2016-10-13	Rutgers, The State University Of New Jersey	Kojic acid polymers
EP3600438A4 (de)	2017-03-29	2020-10-28	Dexcel Pharma Technologies Ltd.	Zusammensetzungen mit biologisch abbaubaren copolymeren
WO2019148294A1 (en)	2018-02-02	2019-08-08	Interface Biologics, Inc.	Dimeric dexamethasone prodrug compositions and uses thereof
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WO2021220061A2 (en)	2020-05-01	2021-11-04	Ripple Therapeutics Corporation	Heterodimer compositions and methods for the treatment of ocular disorders

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1998
- 1998-09-10 CA CA2302508A patent/CA2302508C/en not_active Expired - Fee Related
- 1998-09-10 PT PT98946004T patent/PT1032605E/pt unknown
- 1998-09-10 KR KR1020007002529A patent/KR20010023852A/ko not_active Withdrawn
- 1998-09-10 ES ES98946004T patent/ES2296344T3/es not_active Expired - Lifetime
- 1998-09-10 AU AU93117/98A patent/AU750424C/en not_active Ceased
- 1998-09-10 CN CNB988089629A patent/CN1158325C/zh not_active Expired - Fee Related
- 1998-09-10 DE DE69838731T patent/DE69838731T2/de not_active Expired - Lifetime
- 1998-09-10 AT AT98946004T patent/ATE378364T1/de active
- 1998-09-10 WO PCT/US1998/018816 patent/WO1999012990A1/en not_active Ceased
- 1998-09-10 JP JP2000510791A patent/JP4130305B2/ja not_active Expired - Fee Related
- 1998-09-10 EP EP98946004A patent/EP1032605B1/de not_active Expired - Lifetime
- 1998-09-10 DK DK98946004T patent/DK1032605T3/da active
2007
- 2007-11-29 JP JP2007308503A patent/JP2008150367A/ja active Pending
2008
- 2008-01-14 CY CY20081100048T patent/CY1107857T1/el unknown

Also Published As

Publication number	Publication date
PT1032605E (pt)	2007-12-12
AU750424B2 (en)	2002-07-18
CY1107857T1 (el)	2013-06-19
WO1999012990A1 (en)	1999-03-18
DE69838731T2 (de)	2008-04-10
DE69838731D1 (de)	2007-12-27
JP2008150367A (ja)	2008-07-03
CN1158325C (zh)	2004-07-21
ES2296344T3 (es)	2008-04-16
CN1269811A (zh)	2000-10-11
AU750424C (en)	2003-05-15
AU9311798A (en)	1999-03-29
DK1032605T3 (da)	2008-03-17
CA2302508A1 (en)	1999-03-18
EP1032605B1 (de)	2007-11-14
KR20010023852A (ko)	2001-03-26
JP2001515934A (ja)	2001-09-25
EP1032605A1 (de)	2000-09-06
EP1032605A4 (de)	2002-03-13
JP4130305B2 (ja)	2008-08-06
CA2302508C (en)	2011-03-15

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2008-02-15

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