ATE378421T1 - Glycosyltransferase inhibitoren - Google Patents
Glycosyltransferase inhibitorenInfo
- Publication number
- ATE378421T1 ATE378421T1 AT00936281T AT00936281T ATE378421T1 AT E378421 T1 ATE378421 T1 AT E378421T1 AT 00936281 T AT00936281 T AT 00936281T AT 00936281 T AT00936281 T AT 00936281T AT E378421 T1 ATE378421 T1 AT E378421T1
- Authority
- AT
- Austria
- Prior art keywords
- inhibitors
- glycosyltransferase
- glycosyltransferase inhibitors
- glyscosyltranferase
- glycosyltransferases
- Prior art date
Links
- 239000003297 glycosyltransferase inhibitor Substances 0.000 title abstract 2
- 229930182470 glycoside Natural products 0.000 abstract 2
- 150000002338 glycosides Chemical class 0.000 abstract 2
- 239000003112 inhibitor Substances 0.000 abstract 2
- 108700023372 Glycosyltransferases Proteins 0.000 abstract 1
- 230000031018 biological processes and functions Effects 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000021164 cell adhesion Effects 0.000 abstract 1
- 102000045442 glycosyltransferase activity proteins Human genes 0.000 abstract 1
- 108700014210 glycosyltransferase activity proteins Proteins 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13615099P | 1999-05-24 | 1999-05-24 | |
| US57712099A | 1999-05-24 | 1999-05-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE378421T1 true ATE378421T1 (de) | 2007-11-15 |
Family
ID=26834046
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00936281T ATE378421T1 (de) | 1999-05-24 | 2000-05-24 | Glycosyltransferase inhibitoren |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1185269B1 (de) |
| AT (1) | ATE378421T1 (de) |
| DE (1) | DE60037113T2 (de) |
| WO (1) | WO2001068095A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0421368D0 (en) * | 2004-09-25 | 2004-10-27 | Univ York | Glycosyltransferase assay |
| EP2720044A1 (de) * | 2012-10-15 | 2014-04-16 | National University of Ireland, Galway | Sialyltransferase ST3GAL6 als Marker für multiples Myelom |
| JP2016530265A (ja) | 2013-08-12 | 2016-09-29 | ベナロヤ リサーチ インスティテュート アット バージニア メイソン | 免疫調節のための4−メチルウンベリフェロン処置 |
| CN111437283A (zh) * | 2020-03-09 | 2020-07-24 | 吉林大学 | β1,4-半乳糖基转移酶抑制剂在制备治疗癌症的药物中的应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0576592B1 (de) * | 1991-03-18 | 2000-05-31 | The Scripps Research Institute | Oligosaccharide als enzymsubstrate und -inhibitoren: verfahren und zusammensetzungen |
| CZ120398A3 (cs) * | 1995-09-08 | 1998-12-16 | Novo Nordisk A/S | Použití 2-alkylpyrrolidinových derivátů pro přípravu léčiva pro léčbu diabetu, 2-alkylpyrrolidiné deriváty |
| US5770407A (en) * | 1996-12-10 | 1998-06-23 | The Scripps Research Institute | Process for preparing nucleotide inhibitors of glycosyltransferases |
-
2000
- 2000-05-24 DE DE60037113T patent/DE60037113T2/de not_active Expired - Lifetime
- 2000-05-24 WO PCT/US2000/014360 patent/WO2001068095A1/en not_active Ceased
- 2000-05-24 EP EP00936281A patent/EP1185269B1/de not_active Expired - Lifetime
- 2000-05-24 AT AT00936281T patent/ATE378421T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001068095A1 (en) | 2001-09-20 |
| DE60037113T2 (de) | 2008-09-18 |
| EP1185269A1 (de) | 2002-03-13 |
| EP1185269B1 (de) | 2007-11-14 |
| DE60037113D1 (de) | 2007-12-27 |
| EP1185269A4 (de) | 2004-12-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |