ATE408697T1 - Enzymatische umwandlung von gdp-mannose in gdp- fucose - Google Patents
Enzymatische umwandlung von gdp-mannose in gdp- fucoseInfo
- Publication number
- ATE408697T1 ATE408697T1 AT99903116T AT99903116T ATE408697T1 AT E408697 T1 ATE408697 T1 AT E408697T1 AT 99903116 T AT99903116 T AT 99903116T AT 99903116 T AT99903116 T AT 99903116T AT E408697 T1 ATE408697 T1 AT E408697T1
- Authority
- AT
- Austria
- Prior art keywords
- gdp
- fucose
- mannose
- enzymatic conversion
- synthesis
- Prior art date
Links
- MVMSCBBUIHUTGJ-GDJBGNAASA-N GDP-alpha-D-mannose Chemical compound C([C@H]1O[C@H]([C@@H]([C@@H]1O)O)N1C=2N=C(NC(=O)C=2N=C1)N)OP(O)(=O)OP(O)(=O)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O MVMSCBBUIHUTGJ-GDJBGNAASA-N 0.000 title abstract 2
- LQEBEXMHBLQMDB-JGQUBWHWSA-N GDP-beta-L-fucose Chemical compound O[C@H]1[C@H](O)[C@H](O)[C@H](C)O[C@@H]1OP(O)(=O)OP(O)(=O)OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C3=C(C(NC(N)=N3)=O)N=C2)O1 LQEBEXMHBLQMDB-JGQUBWHWSA-N 0.000 title abstract 2
- 238000006243 chemical reaction Methods 0.000 title abstract 2
- 230000002255 enzymatic effect Effects 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 238000003786 synthesis reaction Methods 0.000 abstract 2
- MVMSCBBUIHUTGJ-UHFFFAOYSA-N 10108-97-1 Natural products C1=2NC(N)=NC(=O)C=2N=CN1C(C(C1O)O)OC1COP(O)(=O)OP(O)(=O)OC1OC(CO)C(O)C(O)C1O MVMSCBBUIHUTGJ-UHFFFAOYSA-N 0.000 abstract 1
- LQEBEXMHBLQMDB-UHFFFAOYSA-N GDP-L-fucose Natural products OC1C(O)C(O)C(C)OC1OP(O)(=O)OP(O)(=O)OCC1C(O)C(O)C(N2C3=C(C(N=C(N)N3)=O)N=C2)O1 LQEBEXMHBLQMDB-UHFFFAOYSA-N 0.000 abstract 1
- 229920001542 oligosaccharide Polymers 0.000 abstract 1
- 150000002482 oligosaccharides Chemical class 0.000 abstract 1
- 239000000376 reactant Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/32—Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7107698P | 1998-01-15 | 1998-01-15 | |
| US09/231,905 US6500661B1 (en) | 1998-01-15 | 1999-01-14 | Enzymatic conversion of GDP-mannose to GDP-fucose |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE408697T1 true ATE408697T1 (de) | 2008-10-15 |
Family
ID=22099098
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99903116T ATE408697T1 (de) | 1998-01-15 | 1999-01-15 | Enzymatische umwandlung von gdp-mannose in gdp- fucose |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US6500661B1 (de) |
| EP (1) | EP1045916B1 (de) |
| JP (1) | JP2004512002A (de) |
| AT (1) | ATE408697T1 (de) |
| AU (1) | AU760626B2 (de) |
| CA (1) | CA2318377A1 (de) |
| MX (1) | MXPA00007675A (de) |
| WO (1) | WO1999036555A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1306207B1 (it) * | 1999-01-15 | 2001-05-30 | Biopolo S C A R L | Produzione di proteine eterologhe da zygosaccharomyces bailii. |
| JP2001112488A (ja) * | 1999-08-10 | 2001-04-24 | Kyowa Hakko Kogyo Co Ltd | Ｇｄｐ−フコースの製造法 |
| US6875591B1 (en) * | 1999-08-10 | 2005-04-05 | Kyowa, Hakko Kogyo Co., Ltd. | Process for producing GDP-fucose |
| JP2001145488A (ja) | 1999-11-19 | 2001-05-29 | Natl Inst Of Advanced Industrial Science & Technology Meti | シロイヌナズナ由来のｇｄｐ−４−ケト−６−デオキシ−ｄ−マンノース−３，５−エピメラーゼ−４−レダクターゼ遺伝子 |
| WO2001041804A1 (en) * | 1999-12-08 | 2001-06-14 | Ramot University Authority For Applied Research & Industrial Development Ltd. | Modulation and assay of fx activity in cells in cancer, inflammatory responses and diseases and in autoimmunity |
| EP1517701A2 (de) * | 2002-04-22 | 2005-03-30 | Recopharma AB | Lewis-y-epitop enthaltende mucin-fusionspolypeptid-vakzine, zusammensetzungen und anwendungsverfahren dafür |
| ATE506450T1 (de) | 2002-07-23 | 2011-05-15 | Biogenerix Ag | Synthese von oligosacchariden, glykolipiden und glykoproteinen unter verwendung bakterieller glykosyltransferasen |
| US20100120701A1 (en) * | 2008-09-25 | 2010-05-13 | Glycosyn, Inc. | Compositions and Methods For Engineering Probiotic Yeast |
| EP2944690B1 (de) * | 2010-10-11 | 2017-12-20 | Jennewein Biotechnologie GmbH | Neuartige fucosyltransferasen und deren anwendungen |
| US12077792B2 (en) * | 2018-05-15 | 2024-09-03 | The Board Of Trustees Of The University Of Illinois | Engineered microorganisms for production of 2′fucosyllactose and l-fucose |
| CN116355822A (zh) * | 2023-03-21 | 2023-06-30 | 中国科学院上海高等研究院 | 一种生产l-岩藻糖的重组枯草芽孢杆菌及其构建方法和应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6214305A (ja) * | 1985-07-12 | 1987-01-22 | Fujitsu Ltd | 磁気テ−プ装置のライトエラ−処理方法 |
| US5374655A (en) | 1991-06-10 | 1994-12-20 | Alberta Research Council | Methods for the synthesis of monofucosylated oligosaccharides terminating in di-N-acetyllactosaminyl structures |
| US5352670A (en) | 1991-06-10 | 1994-10-04 | Alberta Research Council | Methods for the enzymatic synthesis of alpha-sialylated oligosaccharide glycosides |
| US5374541A (en) | 1993-05-04 | 1994-12-20 | The Scripps Research Institute | Combined use of β-galactosidase and sialyltransferase coupled with in situ regeneration of CMP-sialic acid for one pot synthesis of oligosaccharides |
| KR100555161B1 (ko) | 1996-09-17 | 2006-11-30 | 교와 핫꼬 고교 가부시끼가이샤 | 당뉴클레오티드류및복합당질의제조법 |
| US5728568A (en) | 1996-11-22 | 1998-03-17 | Genetics Institute, Inc. | Human GDP-mannose 4,6 dehydratase |
| DE19735994A1 (de) | 1997-08-19 | 1999-02-25 | Piepersberg Wolfgang Prof Dr | Verfahren zur enzymatischen Synthese von Guanosindiphosphat-6-desoxyhexosen und deren Verwendung zur Herstellung von Oligosacchariden |
| JP3823095B2 (ja) * | 2003-04-17 | 2006-09-20 | インターナショナル・ビジネス・マシーンズ・コーポレーション | 記憶装置、制御方法、プログラム、プログラム記録媒体、及びデータ記録媒体 |
| JP2005092659A (ja) * | 2003-09-19 | 2005-04-07 | Nec Electronics Corp | データ書込・読出制御装置、及びデータ書込・読出制御方法 |
-
1999
- 1999-01-14 US US09/231,905 patent/US6500661B1/en not_active Expired - Fee Related
- 1999-01-15 AU AU23217/99A patent/AU760626B2/en not_active Ceased
- 1999-01-15 JP JP2000540256A patent/JP2004512002A/ja active Pending
- 1999-01-15 MX MXPA00007675A patent/MXPA00007675A/es not_active IP Right Cessation
- 1999-01-15 WO PCT/US1999/000893 patent/WO1999036555A1/en not_active Ceased
- 1999-01-15 AT AT99903116T patent/ATE408697T1/de not_active IP Right Cessation
- 1999-01-15 CA CA002318377A patent/CA2318377A1/en not_active Abandoned
- 1999-01-15 EP EP99903116A patent/EP1045916B1/de not_active Expired - Lifetime
-
2002
- 2002-07-25 US US10/206,425 patent/US7247456B2/en not_active Expired - Fee Related
- 2002-07-25 US US10/206,485 patent/US20030134403A1/en not_active Abandoned
- 2002-07-25 US US10/206,655 patent/US7026142B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA00007675A (es) | 2002-04-24 |
| US20030134403A1 (en) | 2003-07-17 |
| WO1999036555A1 (en) | 1999-07-22 |
| US20030143567A1 (en) | 2003-07-31 |
| JP2004512002A (ja) | 2004-04-22 |
| US6500661B1 (en) | 2002-12-31 |
| EP1045916A1 (de) | 2000-10-25 |
| AU760626B2 (en) | 2003-05-22 |
| US7247456B2 (en) | 2007-07-24 |
| US20060234354A1 (en) | 2006-10-19 |
| AU2321799A (en) | 1999-08-02 |
| EP1045916B1 (de) | 2008-09-17 |
| US7026142B2 (en) | 2006-04-11 |
| CA2318377A1 (en) | 1999-07-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties | ||
| REN | Ceased due to non-payment of the annual fee |