ATE38036T1 - Benzothiophenderivate als bronchodilatoren. - Google Patents

Benzothiophenderivate als bronchodilatoren.

Info

Publication number
ATE38036T1
ATE38036T1 AT84306226T AT84306226T ATE38036T1 AT E38036 T1 ATE38036 T1 AT E38036T1 AT 84306226 T AT84306226 T AT 84306226T AT 84306226 T AT84306226 T AT 84306226T AT E38036 T1 ATE38036 T1 AT E38036T1
Authority
AT
Austria
Prior art keywords
bronchodilators
benzothiophene derivatives
derivatives
benzothiophene
formulations
Prior art date
Application number
AT84306226T
Other languages
English (en)
Inventor
Peter Peck Koh Ho
Quentin Francis Soper
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE38036T1 publication Critical patent/ATE38036T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Seal Device For Vehicle (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
AT84306226T 1983-09-13 1984-09-12 Benzothiophenderivate als bronchodilatoren. ATE38036T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/531,802 US4552891A (en) 1983-09-13 1983-09-13 Benzothiophene derivatives
EP84306226A EP0139464B1 (de) 1983-09-13 1984-09-12 Benzothiophenderivate als Bronchodilatoren

Publications (1)

Publication Number Publication Date
ATE38036T1 true ATE38036T1 (de) 1988-11-15

Family

ID=24119104

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84306226T ATE38036T1 (de) 1983-09-13 1984-09-12 Benzothiophenderivate als bronchodilatoren.

Country Status (18)

Country Link
US (1) US4552891A (de)
EP (1) EP0139464B1 (de)
JP (1) JPS6084221A (de)
AT (1) ATE38036T1 (de)
AU (1) AU563650B2 (de)
CA (1) CA1229047A (de)
CY (1) CY1513A (de)
DE (2) DE3474662D1 (de)
DK (1) DK158972C (de)
GB (1) GB2146527B (de)
HK (1) HK38990A (de)
IL (1) IL72928A (de)
IT (1) IT1176702B (de)
MY (1) MY101614A (de)
NZ (1) NZ209516A (de)
PH (1) PH21102A (de)
SG (1) SG74789G (de)
ZA (1) ZA847193B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0253650A3 (de) * 1986-07-18 1989-09-13 Eli Lilly And Company Benzothiophen-Derivate
GB8816519D0 (en) * 1987-07-23 1988-08-17 Ici Plc Antibiotic compounds
US4863923A (en) * 1988-07-01 1989-09-05 Eli Lilly And Company Method of inhibiting superoxide release
NZ248573A (en) * 1992-09-10 1996-02-27 Lilly Co Eli 5-arylmethyl (and methylidene) thiazolidin-4-one derivatives; their preparation and pharmaceutical compositions
US6251928B1 (en) * 1994-03-16 2001-06-26 Eli Lilly And Company Treatment of alzheimer's disease employing inhibitors of cathepsin D
US6132757A (en) * 1998-05-01 2000-10-17 Neal R. Cutler Treatment of sexual dysfunction in certain patient groups
US6187790B1 (en) 1999-03-04 2001-02-13 Neal R. Cutler Use of cilostazol for treatment of sexual dysfunction
US6426084B1 (en) 2000-06-19 2002-07-30 Neal R. Cutler Treatment of sexual dysfunction in certain patient groups
CA2715683A1 (en) 1999-08-21 2001-03-01 Nycomed Gmbh Synergistic combination
US6458804B1 (en) * 2001-01-26 2002-10-01 R.T. Alamo Venturesi, Llc Methods for the treatment of central nervous system disorders in certain patient groups
US6451813B1 (en) 2001-01-26 2002-09-17 R. T. Alamo Ventures I, Llc Treatment of gastroparesis in certain patient groups
US6562838B2 (en) * 2001-01-26 2003-05-13 R. T. Alamo Ventures I, L.L.C. Treatment of cardiovascular disease with quinolinone enantiomers
US20030096748A1 (en) * 2001-06-04 2003-05-22 The Regents Of The University Of Michigan Methods and compositions for the treatment of diseases associated with signal transduction aberrations
US7041677B2 (en) * 2002-03-01 2006-05-09 R.T. Alamo Ventures I, Llc Use of monochloroflosequinan in the treatment of sexual dysfunction
US7208628B2 (en) * 2002-05-13 2007-04-24 Kansas State University Research Foundation Compositions and methods for the treatment of hepatitis C virus infection
US7074893B2 (en) * 2002-06-03 2006-07-11 Regents Of The University Of Michigan Methods and compositions for the treatment of diseases associated with signal transduction aberrations
US7153824B2 (en) 2003-04-01 2006-12-26 Applied Research Systems Ars Holding N.V. Inhibitors of phosphodiesterases in infertility
US20050089558A1 (en) * 2003-10-28 2005-04-28 Alamo Pharmaceuticals, Llc Compositions and methods for the co-formulation and administration of tramadol and propoxyphene
WO2007098010A2 (en) * 2006-02-17 2007-08-30 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Improved low molecular weight myc-max inhibitors
US10494405B2 (en) 2015-05-15 2019-12-03 The Regents Of The University Of Michigan Methods and compositions for the treatment of arthritis
CA3079848A1 (en) 2017-11-07 2019-05-16 The Regents Of The University Of Michigan Small molecule inhibitors of shared epitope-calreticulin interactions and methods of use

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH508615A (de) * 1968-05-30 1971-06-15 Ciba Geigy Ag Verfahren zur Herstellung von neuen heterocyclischen Carbonsäuren
US4101668A (en) * 1977-05-10 1978-07-18 Bristol-Myers Company Antiosteoporotic agents

Also Published As

Publication number Publication date
IL72928A0 (en) 1984-12-31
MY101614A (en) 1991-12-17
DE3433475C2 (de) 1992-12-24
JPS6084221A (ja) 1985-05-13
NZ209516A (en) 1987-01-23
EP0139464A1 (de) 1985-05-02
US4552891A (en) 1985-11-12
DE3433475A1 (de) 1985-03-28
AU563650B2 (en) 1987-07-16
EP0139464B1 (de) 1988-10-19
DK434884D0 (da) 1984-09-12
DK434884A (da) 1985-03-14
DE3474662D1 (en) 1988-11-24
GB8423081D0 (en) 1984-10-17
GB2146527B (en) 1987-05-20
DK158972B (da) 1990-08-13
CA1229047A (en) 1987-11-10
ZA847193B (en) 1986-04-30
IT8422626A0 (it) 1984-09-12
SG74789G (en) 1990-04-20
IL72928A (en) 1987-10-20
DK158972C (da) 1991-01-07
IT8422626A1 (it) 1986-03-12
GB2146527A (en) 1985-04-24
PH21102A (en) 1987-07-16
AU3192084A (en) 1985-03-21
CY1513A (en) 1990-08-03
IT1176702B (it) 1987-08-18
HK38990A (en) 1990-05-25

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee