ATE381017T1 - Kathepsin y inhibitoren für die entwicklung von medikamenten zur schmerzbehandlung - Google Patents
Kathepsin y inhibitoren für die entwicklung von medikamenten zur schmerzbehandlungInfo
- Publication number
- ATE381017T1 ATE381017T1 AT02003400T AT02003400T ATE381017T1 AT E381017 T1 ATE381017 T1 AT E381017T1 AT 02003400 T AT02003400 T AT 02003400T AT 02003400 T AT02003400 T AT 02003400T AT E381017 T1 ATE381017 T1 AT E381017T1
- Authority
- AT
- Austria
- Prior art keywords
- cathepsin
- development
- inhibitors
- pain treatment
- treatment medications
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 3
- 102000005600 Cathepsins Human genes 0.000 title 1
- 108010084457 Cathepsins Proteins 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 102100026657 Cathepsin Z Human genes 0.000 abstract 2
- 108010015575 cathepsin Y Proteins 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 238000012512 characterization method Methods 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/702—Specific hybridization probes for retroviruses
- C12Q1/703—Viruses associated with AIDS
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4873—Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96466—Cysteine endopeptidases (3.4.22)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Pathology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- AIDS & HIV (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02003400A EP1336847B1 (de) | 2002-02-14 | 2002-02-14 | Kathepsin Y Inhibitoren für die Entwicklung von Medikamenten zur Schmerzbehandlung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE381017T1 true ATE381017T1 (de) | 2007-12-15 |
Family
ID=27619135
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02003400T ATE381017T1 (de) | 2002-02-14 | 2002-02-14 | Kathepsin y inhibitoren für die entwicklung von medikamenten zur schmerzbehandlung |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1336847B1 (de) |
| AT (1) | ATE381017T1 (de) |
| DE (1) | DE60224002T2 (de) |
| ES (1) | ES2296834T3 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004077053A1 (en) * | 2003-02-25 | 2004-09-10 | Biofrontera Pharmaceuticals Gmbh | Cathepsin y for the treatment of pain |
| WO2005065693A2 (en) * | 2003-12-30 | 2005-07-21 | Aventis Pharmaceuticals Inc. | Use of cathepsin z inhibitors for the treatment of rheumatoid arthritis and other autoimmune diseases |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0831920A4 (de) * | 1995-06-06 | 2003-03-19 | Athena Neurosciences Inc | Neues cathepsin sowie verfahren und zusammensetzungen zur inhibierung desselben |
| AU1926699A (en) * | 1997-12-18 | 1999-07-05 | Immunex Corporation | Cathepsin dc proteins, dna encoding the proteins, and their use in human cancer prognosis |
| WO2001023570A2 (en) * | 1999-09-30 | 2001-04-05 | Ortho-Mcneil Pharmaceutical, Inc. | Methods and compositions relating to sodium channel beta-1a subunits |
-
2002
- 2002-02-14 DE DE60224002T patent/DE60224002T2/de not_active Expired - Fee Related
- 2002-02-14 ES ES02003400T patent/ES2296834T3/es not_active Expired - Lifetime
- 2002-02-14 EP EP02003400A patent/EP1336847B1/de not_active Expired - Lifetime
- 2002-02-14 AT AT02003400T patent/ATE381017T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2296834T3 (es) | 2008-05-01 |
| EP1336847B1 (de) | 2007-12-12 |
| EP1336847A1 (de) | 2003-08-20 |
| DE60224002T2 (de) | 2008-11-06 |
| DE60224002D1 (de) | 2008-01-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE60311272D1 (de) | Neue purin- oder pyrrolol(2,3-d)pyrimidin-2-carbonsäurenitrile zur behandlung von mit cysteinproteaseaktivität assoziierten krankheiten | |
| ATE389724T1 (de) | Menschliche dnase i hyperaktive varianten | |
| ATE364698T1 (de) | Neues, physiologisch aktives peptid und dessen verwendung | |
| ATE450269T1 (de) | Peptid pyyä3-36ü zur behandlung von stoffwechselkrankheiten | |
| PL2157192T3 (pl) | Kompozycje do diagnozowania i terapii chorób związanych z nieprawidłową ekspresją futrin (R-spondin) | |
| TR200201094T2 (tr) | Farmasötik maddeler olarak bisiklik amino asitler | |
| BR0316502A (pt) | Compostos quìmicos | |
| DE602004017202D1 (de) | Caseinhydrolysat, verfahren zur dessen herstellung sowie dessen verwendung | |
| ATE370968T1 (de) | Varianten des menschliche koagulationsfaktors vii | |
| ATE458057T1 (de) | Varianten der faktor-vii- oder -viia-gla-domäne | |
| DE60306505D1 (de) | Verfahren zur behandlung von brustdrüsenerkrankungen | |
| ATE427116T1 (de) | Behandlung von bakteriellen infektionen | |
| DE60218843D1 (de) | Verfahren zur identifizierung von mitteln zur behandlung von diabetes | |
| ATE344262T1 (de) | 2-heteroarylcarbonsäureamide | |
| ATE245439T1 (de) | Inhibitoren für homöostase und immunfunktion | |
| ATE395602T1 (de) | Verwendung von hmgb-proteinen und dafür codierenden nukleinsäuren | |
| ATE381017T1 (de) | Kathepsin y inhibitoren für die entwicklung von medikamenten zur schmerzbehandlung | |
| WO2004050685A3 (en) | Antifungal therapeutic agents | |
| ATE363923T1 (de) | Verwendung von flumazenil zur herstellung eines medikaments für die behandlung von kokainabhängigkeit | |
| DE60216457D1 (de) | Carbamate verbindungen zur behandlung oder verhutung von psychotischen krankheiten | |
| ATE225171T1 (de) | Aminosäurederivate zur behandlung von schlaganfall | |
| ATE166656T1 (de) | Humanes galanin, cdna-klone die für humanes galanin kodieren und eine methode humanes galamin herzustellen | |
| DE602004004754D1 (de) | Peptizusammensetzung für die Mundhöhle | |
| ATE374593T1 (de) | Methode zur haarbehandlung gekennzeichnet durch applikation bestimmter 2-hydroxyalkansäuren | |
| DE60120187D1 (de) | Verkürztes bard1 protein und dessen diagnostische und therapeutische anwendungen |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |