ATE381617T1 - Glycoprotein hormone (tsh) superagonists - Google Patents

Glycoprotein hormone (tsh) superagonists

Info

Publication number
ATE381617T1
ATE381617T1 AT96920151T AT96920151T ATE381617T1 AT E381617 T1 ATE381617 T1 AT E381617T1 AT 96920151 T AT96920151 T AT 96920151T AT 96920151 T AT96920151 T AT 96920151T AT E381617 T1 ATE381617 T1 AT E381617T1
Authority
AT
Austria
Prior art keywords
human
hormone
amino acids
directed
hormones
Prior art date
Application number
AT96920151T
Other languages
English (en)
Inventor
Mariusz Szkudlinski
Bruce Weintraub
Mathis Grossman
Original Assignee
Us Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Health filed Critical Us Health
Application granted granted Critical
Publication of ATE381617T1 publication Critical patent/ATE381617T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT96920151T 1996-05-08 1996-05-08 Glycoprotein hormone (tsh) superagonists ATE381617T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1996/006483 WO1997042322A1 (en) 1996-05-08 1996-05-08 Glycoprotein hormone superagonists

Publications (1)

Publication Number Publication Date
ATE381617T1 true ATE381617T1 (de) 2008-01-15

Family

ID=22255059

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96920151T ATE381617T1 (de) 1996-05-08 1996-05-08 Glycoprotein hormone (tsh) superagonists

Country Status (8)

Country Link
EP (2) EP0954578B1 (de)
JP (1) JP3981413B2 (de)
KR (1) KR20040039320A (de)
AT (1) ATE381617T1 (de)
AU (1) AU714635B2 (de)
CA (1) CA2253441C (de)
DE (1) DE69637375T2 (de)
WO (1) WO1997042322A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6361992B1 (en) 1996-05-08 2002-03-26 The United States Of America As Represented By The Department Of Health And Human Services Thyroid stimulating hormone superagonists
KR20070026463A (ko) * 2004-03-19 2007-03-08 트로포젠 인코포레이티드 여포자극호로몬 초작동제
EP1738174A2 (de) * 2004-03-31 2007-01-03 Trophogen, Inc. Menschliche glycoproteinhormon-superagonisten und verwendungen davon
RU2668174C2 (ru) 2012-07-30 2018-09-26 Трофоген Инк. Суперагонисты гликопротеинового гормона длительного действия
US10457713B2 (en) 2012-07-30 2019-10-29 Trophogen, Inc. Glycoprotein hormone long-acting superagonists
CN105873602A (zh) 2013-11-05 2016-08-17 特洛佛根股份有限公司 糖蛋白激素长效超激动剂
KR101947341B1 (ko) * 2017-05-05 2019-02-12 주식회사 유비프로틴 FSHβ 반감기를 증가시키는 방법
KR101947340B1 (ko) * 2017-05-05 2019-02-12 주식회사 유비프로틴 FSHα 반감기를 증가시키는 방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03502525A (ja) * 1988-09-01 1991-06-13 アプライド・リサーチ・システムス・エー・アール・エス・ホールディング・エヌ・ブイ ゴナドトロピンおよびｔｓｈのスーパーアゴニストの製造方法並びに該製造方法で製造したスーパーアゴニスト
EP0404458A3 (de) * 1989-06-19 1992-03-04 Bunge (Australia) Proprietary Limited Follikelstimulierendes Schafhormon
AU672969B2 (en) 1992-03-10 1996-10-24 United States of America, as represented by The Secretary, Department of Health & Human Services, The Exchangeable template reaction

Also Published As

Publication number Publication date
JP2000509603A (ja) 2000-08-02
DE69637375D1 (en) 2008-01-31
KR20040039320A (ko) 2004-05-10
WO1997042322A1 (en) 1997-11-13
AU714635B2 (en) 2000-01-06
EP1947117B1 (de) 2013-07-17
EP1947117A2 (de) 2008-07-23
CA2253441C (en) 2013-07-16
DE69637375T2 (de) 2009-02-12
AU5854996A (en) 1997-11-26
JP3981413B2 (ja) 2007-09-26
EP0954578B1 (de) 2007-12-19
EP0954578A1 (de) 1999-11-10
CA2253441A1 (en) 1997-11-13
EP1947117A3 (de) 2008-10-08

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Legal Events

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