ATE381964T1 - Fokussierte akustische energie in der herstellung und screening von kombinatorischen bibliotheken - Google Patents
Fokussierte akustische energie in der herstellung und screening von kombinatorischen bibliothekenInfo
- Publication number
- ATE381964T1 ATE381964T1 AT01973543T AT01973543T ATE381964T1 AT E381964 T1 ATE381964 T1 AT E381964T1 AT 01973543 T AT01973543 T AT 01973543T AT 01973543 T AT01973543 T AT 01973543T AT E381964 T1 ATE381964 T1 AT E381964T1
- Authority
- AT
- Austria
- Prior art keywords
- screening
- manufacturing
- matter
- acoustic energy
- focused acoustic
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000012216 screening Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 3
- 239000000758 substrate Substances 0.000 abstract 2
Classifications
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- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B80/00—Linkers or spacers specially adapted for combinatorial chemistry or libraries, e.g. traceless linkers or safety-catch linkers
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
- B41J—TYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
- B41J2/00—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed
- B41J2/005—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed characterised by bringing liquid or particles selectively into contact with a printing material
- B41J2/01—Ink jet
- B41J2/015—Ink jet characterised by the jet generation process
- B41J2/04—Ink jet characterised by the jet generation process generating single droplets or particles on demand
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
- B41J—TYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
- B41J2/00—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed
- B41J2/005—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed characterised by bringing liquid or particles selectively into contact with a printing material
- B41J2/01—Ink jet
- B41J2/135—Nozzles
- B41J2/14—Structure thereof only for on-demand ink jet heads
- B41J2/14008—Structure of acoustic ink jet print heads
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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- B01J2219/00378—Piezoelectric or ink jet dispensers
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00527—Sheets
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01J2219/00585—Parallel processes
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- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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- B01J2219/0059—Sequential processes
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01J2219/00608—DNA chips
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- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
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- B01J2219/00612—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports the surface being inorganic
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01J2219/00617—Delimitation of the attachment areas by chemical means
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- B01J2219/00583—Features relative to the processes being carried out
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- B01J2219/00621—Delimitation of the attachment areas by physical means, e.g. trenches, raised areas
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- B01J2219/00718—Type of compounds synthesised
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0433—Moving fluids with specific forces or mechanical means specific forces vibrational forces
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
- B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
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- C—CHEMISTRY; METALLURGY
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- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/11—Compounds covalently bound to a solid support
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- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
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- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
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- C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
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- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Golf Clubs (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Laminated Bodies (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66999600A | 2000-09-25 | 2000-09-25 | |
| US09/727,392 US20020061258A1 (en) | 2000-09-25 | 2000-11-29 | Focused acoustic energy in the preparation and screening of combinatorial libraries |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE381964T1 true ATE381964T1 (de) | 2008-01-15 |
Family
ID=24688564
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01973543T ATE381964T1 (de) | 2000-09-25 | 2001-09-25 | Fokussierte akustische energie in der herstellung und screening von kombinatorischen bibliotheken |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20020061258A1 (de) |
| EP (1) | EP1870157A3 (de) |
| AT (1) | ATE381964T1 (de) |
| AU (1) | AU2001294733A1 (de) |
| DE (1) | DE60132099T2 (de) |
| WO (1) | WO2002024323A2 (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020037359A1 (en) | 2000-09-25 | 2002-03-28 | Mutz Mitchell W. | Focused acoustic energy in the preparation of peptide arrays |
| US6806051B2 (en) | 2000-09-25 | 2004-10-19 | Picoliter Inc. | Arrays of partially nonhybridizing oligonucleotides and preparation thereof using focused acoustic energy |
| US20030048341A1 (en) * | 2000-09-25 | 2003-03-13 | Mutz Mitchell W. | High-throughput biomolecular crystallization and biomolecular crystal screening |
| US6808934B2 (en) | 2000-09-25 | 2004-10-26 | Picoliter Inc. | High-throughput biomolecular crystallization and biomolecular crystal screening |
| US6596239B2 (en) * | 2000-12-12 | 2003-07-22 | Edc Biosystems, Inc. | Acoustically mediated fluid transfer methods and uses thereof |
| US20020106812A1 (en) * | 2001-01-26 | 2002-08-08 | Fisher William D. | Fluid drop dispensing |
| US6707038B2 (en) | 2001-02-14 | 2004-03-16 | Picoliter Inc. | Method and system using acoustic ejection for selective fluid deposition on a nonuniform sample surface |
| US6855925B2 (en) | 2001-02-14 | 2005-02-15 | Picoliter Inc. | Methods, devices, and systems using acoustic ejection for depositing fluid droplets on a sample surface for analysis |
| EP1366356B1 (de) | 2001-02-14 | 2010-07-21 | Picoliter, Inc. | Einführung akustischer proben zur analyse und/oder verarbeitung |
| US6416164B1 (en) | 2001-07-20 | 2002-07-09 | Picoliter Inc. | Acoustic ejection of fluids using large F-number focusing elements |
| US6976639B2 (en) | 2001-10-29 | 2005-12-20 | Edc Biosystems, Inc. | Apparatus and method for droplet steering |
| US6925856B1 (en) | 2001-11-07 | 2005-08-09 | Edc Biosystems, Inc. | Non-contact techniques for measuring viscosity and surface tension information of a liquid |
| US7354141B2 (en) | 2001-12-04 | 2008-04-08 | Labcyte Inc. | Acoustic assessment of characteristics of a fluid relevant to acoustic ejection |
| US7429359B2 (en) * | 2002-12-19 | 2008-09-30 | Edc Biosystems, Inc. | Source and target management system for high throughput transfer of liquids |
| US7275807B2 (en) * | 2002-11-27 | 2007-10-02 | Edc Biosystems, Inc. | Wave guide with isolated coupling interface |
| GB0303861D0 (en) * | 2003-02-20 | 2003-03-26 | Arrayjet Ltd | Improved printing method and apparatus |
| DE102004062281A1 (de) * | 2003-12-29 | 2005-07-28 | Siemens Ag | Verfahren und Spotting-Lösung zum Herstellen von Microarrays |
| TWI537203B (zh) * | 2007-11-27 | 2016-06-11 | 惠普研發公司 | 製備滴定系列之技術 |
| CN113262724B (zh) * | 2021-05-13 | 2022-08-26 | 宁夏胜蓝化工环保科技有限公司 | 一种用于硅酸甲酯直接法合成的反应器 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4877745A (en) * | 1986-11-17 | 1989-10-31 | Abbott Laboratories | Apparatus and process for reagent fluid dispensing and printing |
| US4797693A (en) * | 1987-06-02 | 1989-01-10 | Xerox Corporation | Polychromatic acoustic ink printing |
| CA2124087C (en) * | 1991-11-22 | 2002-10-01 | James L. Winkler | Combinatorial strategies for polymer synthesis |
| US5629724A (en) * | 1992-05-29 | 1997-05-13 | Xerox Corporation | Stabilization of the free surface of a liquid |
| US6015880A (en) * | 1994-03-16 | 2000-01-18 | California Institute Of Technology | Method and substrate for performing multiple sequential reactions on a matrix |
| US5669971A (en) * | 1994-04-06 | 1997-09-23 | Specialty Coating Systems, Inc. | Selective coating apparatus |
| US5807522A (en) * | 1994-06-17 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for fabricating microarrays of biological samples |
| US5985356A (en) * | 1994-10-18 | 1999-11-16 | The Regents Of The University Of California | Combinatorial synthesis of novel materials |
| JP3296213B2 (ja) * | 1996-10-30 | 2002-06-24 | 三菱電機株式会社 | 液体エジェクタおよび液体エジェクタを用いる印刷装置 |
| US5877580A (en) * | 1996-12-23 | 1999-03-02 | Regents Of The University Of California | Micromachined chemical jet dispenser |
| DE29823691U1 (de) * | 1998-04-16 | 1999-09-23 | EVOTEC BioSystems AG, 22525 Hamburg | Vorrichtung zum Erzeugen und Ausstoßen kleiner Fluidtropfen mit einer als reflektivem akustischen Element ausgebildeten Druckkammer |
| US6048699A (en) * | 1998-10-19 | 2000-04-11 | Motorola, Inc. | Method of fabricating bio-chip arrays |
| JP4624644B2 (ja) * | 2000-09-25 | 2011-02-02 | ピコリター インコーポレイテッド | 複数のリザブワーからの流体の音響出射 |
| US20030048341A1 (en) * | 2000-09-25 | 2003-03-13 | Mutz Mitchell W. | High-throughput biomolecular crystallization and biomolecular crystal screening |
| US6596239B2 (en) * | 2000-12-12 | 2003-07-22 | Edc Biosystems, Inc. | Acoustically mediated fluid transfer methods and uses thereof |
-
2000
- 2000-11-29 US US09/727,392 patent/US20020061258A1/en not_active Abandoned
-
2001
- 2001-09-25 DE DE60132099T patent/DE60132099T2/de not_active Expired - Lifetime
- 2001-09-25 AU AU2001294733A patent/AU2001294733A1/en not_active Abandoned
- 2001-09-25 WO PCT/US2001/030087 patent/WO2002024323A2/en not_active Ceased
- 2001-09-25 AT AT01973543T patent/ATE381964T1/de not_active IP Right Cessation
- 2001-09-25 EP EP07003181A patent/EP1870157A3/de not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP1870157A3 (de) | 2008-02-20 |
| WO2002024323A3 (en) | 2003-02-13 |
| US20020061258A1 (en) | 2002-05-23 |
| AU2001294733A1 (en) | 2002-04-02 |
| DE60132099D1 (de) | 2008-02-07 |
| WO2002024323A2 (en) | 2002-03-28 |
| EP1870157A2 (de) | 2007-12-26 |
| DE60132099T2 (de) | 2008-12-11 |
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| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |