ATE464123T1 - Elektrosprühen von lösungen zur massenherstellung von chips und molekülbibliotheken - Google Patents

Elektrosprühen von lösungen zur massenherstellung von chips und molekülbibliotheken

Info

Publication number
ATE464123T1
ATE464123T1 AT98929102T AT98929102T ATE464123T1 AT E464123 T1 ATE464123 T1 AT E464123T1 AT 98929102 T AT98929102 T AT 98929102T AT 98929102 T AT98929102 T AT 98929102T AT E464123 T1 ATE464123 T1 AT E464123T1
Authority
AT
Austria
Prior art keywords
chips
mass production
molecule libraries
electrospraying
solutions
Prior art date
Application number
AT98929102T
Other languages
English (en)
Inventor
Victor Morozov
Tamara Morozova
Original Assignee
Univ New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ New York filed Critical Univ New York
Application granted granted Critical
Publication of ATE464123T1 publication Critical patent/ATE464123T1/de

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/545Synthetic resin
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B5/00Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
    • B05B5/002Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means comprising means for neutralising the spray of charged droplets or particules
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B5/00Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
    • B05B5/025Discharge apparatus, e.g. electrostatic spray guns
    • B05B5/0255Discharge apparatus, e.g. electrostatic spray guns spraying and depositing by electrostatic forces only
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00Nanotechnology for materials or surface science, e.g. nanocomposites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
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    • B01J2219/00605Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
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    • B01J2219/0061The surface being organic
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    • B01J2219/00614Delimitation of the attachment areas
    • B01J2219/00617Delimitation of the attachment areas by chemical means
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    • B01J2219/00623Immobilisation or binding
    • B01J2219/00626Covalent
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    • B01J2219/00639Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium
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    • B01J2219/00677Ex-situ synthesis followed by deposition on the substrate
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    • B01J2219/00709Type of synthesis
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    • B01J2219/00718Type of compounds synthesised
    • B01J2219/0072Organic compounds
    • B01J2219/00725Peptides
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B12/00Arrangements for controlling delivery; Arrangements for controlling the spray area
    • B05B12/16Arrangements for controlling delivery; Arrangements for controlling the spray area for controlling the spray area
    • B05B12/32Shielding elements, i.e. elements preventing overspray from reaching areas other than the object to be sprayed
    • B05B12/36Side shields, i.e. shields extending in a direction substantially parallel to the spray jet
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/04Libraries containing only organic compounds
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    • C40B60/00Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Nanotechnology (AREA)
  • Composite Materials (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Electrostatic Spraying Apparatus (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT98929102T 1997-06-20 1998-06-19 Elektrosprühen von lösungen zur massenherstellung von chips und molekülbibliotheken ATE464123T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5027497P 1997-06-20 1997-06-20
US5528797P 1997-08-13 1997-08-13
PCT/US1998/012768 WO1998058745A1 (en) 1997-06-20 1998-06-19 Electrospraying solutions of substances for mass fabrication of chips and libraries

Publications (1)

Publication Number Publication Date
ATE464123T1 true ATE464123T1 (de) 2010-04-15

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AT98929102T ATE464123T1 (de) 1997-06-20 1998-06-19 Elektrosprühen von lösungen zur massenherstellung von chips und molekülbibliotheken

Country Status (9)

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US (3) US6350609B1 (de)
EP (1) EP0988112B1 (de)
JP (1) JP4433100B2 (de)
AT (1) ATE464123T1 (de)
AU (1) AU747022B2 (de)
CA (1) CA2294449A1 (de)
DE (1) DE69841614D1 (de)
NZ (1) NZ502246A (de)
WO (1) WO1998058745A1 (de)

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US20030186311A1 (en) * 1999-05-21 2003-10-02 Bioforce Nanosciences, Inc. Parallel analysis of molecular interactions
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JP2003508043A (ja) * 1999-08-27 2003-03-04 ピコグラム, インコーポレイテッド 荷電されたミクロロケーションにおける操作を実行するための方法およびデバイス
WO2001038873A2 (en) * 1999-11-24 2001-05-31 Biotronic Technologies, Inc. Devices and methods for detecting analytes using electrosensor having capture reagent
WO2001057254A2 (en) * 2000-02-02 2001-08-09 Cartesian Technologies, Inc. Method and apparatus for developing dna microarrays
US6897015B2 (en) * 2000-03-07 2005-05-24 Bioforce Nanosciences, Inc. Device and method of use for detection and characterization of pathogens and biological materials
JP4425420B2 (ja) * 2000-04-03 2010-03-03 独立行政法人理化学研究所 マイクロアレイ作製装置
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JP4433100B2 (ja) 2010-03-17
NZ502246A (en) 2002-10-25
AU8074398A (en) 1999-01-04
US20020048770A1 (en) 2002-04-25
AU747022B2 (en) 2002-05-09
EP0988112B1 (de) 2010-04-14
WO1998058745A9 (en) 1999-04-22
EP0988112A1 (de) 2000-03-29
JP2002511792A (ja) 2002-04-16
EP0988112A4 (de) 2006-09-27
WO1998058745A1 (en) 1998-12-30
US20030150739A1 (en) 2003-08-14
US6350609B1 (en) 2002-02-26
CA2294449A1 (en) 1998-12-30

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