ATE382147T1 - Verfahren und einrichtung zur hochempfindlichen detektion der anwesenheit von dna und weitere sonden - Google Patents
Verfahren und einrichtung zur hochempfindlichen detektion der anwesenheit von dna und weitere sondenInfo
- Publication number
- ATE382147T1 ATE382147T1 AT03760533T AT03760533T ATE382147T1 AT E382147 T1 ATE382147 T1 AT E382147T1 AT 03760533 T AT03760533 T AT 03760533T AT 03760533 T AT03760533 T AT 03760533T AT E382147 T1 ATE382147 T1 AT E382147T1
- Authority
- AT
- Austria
- Prior art keywords
- target sample
- capacitive sensor
- binding site
- substrate
- conductive
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
- G01N27/22—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating capacitance
- G01N27/221—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating capacitance by investigating the dielectric properties
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
- G01N27/22—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating capacitance
- G01N27/226—Construction of measuring vessels; Electrodes therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
- G01N33/5438—Electrodes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/145555—Hetero-N
- Y10T436/147777—Plural nitrogen in the same ring [e.g., barbituates, creatinine, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/16—Phosphorus containing
- Y10T436/163333—Organic [e.g., chemical warfare agents, insecticides, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/17—Nitrogen containing
- Y10T436/173845—Amine and quaternary ammonium
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Electrochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02447122A EP1376111A1 (de) | 2002-06-24 | 2002-06-24 | Verfahren und Vorrichtung für die hochempfindliche Bestimmung von DNA und anderen Testsubstanzen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE382147T1 true ATE382147T1 (de) | 2008-01-15 |
Family
ID=29717039
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03760533T ATE382147T1 (de) | 2002-06-24 | 2003-06-24 | Verfahren und einrichtung zur hochempfindlichen detektion der anwesenheit von dna und weitere sonden |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7943394B2 (de) |
| EP (2) | EP1376111A1 (de) |
| AT (1) | ATE382147T1 (de) |
| AU (1) | AU2003243843A1 (de) |
| DE (1) | DE60318313T2 (de) |
| WO (1) | WO2004001403A1 (de) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0114399D0 (en) * | 2001-06-13 | 2001-08-08 | Univ Liverpool | Substrates, biomaterials and methods |
| EP1376111A1 (de) | 2002-06-24 | 2004-01-02 | Universite Catholique De Louvain | Verfahren und Vorrichtung für die hochempfindliche Bestimmung von DNA und anderen Testsubstanzen |
| WO2005066613A1 (en) * | 2003-12-31 | 2005-07-21 | President And Fellows Of Harvard College | Assay device and method |
| US7742322B2 (en) | 2005-01-07 | 2010-06-22 | Invisage Technologies, Inc. | Electronic and optoelectronic devices with quantum dot films |
| US7746681B2 (en) | 2005-01-07 | 2010-06-29 | Invisage Technologies, Inc. | Methods of making quantum dot films |
| US7326908B2 (en) | 2004-04-19 | 2008-02-05 | Edward Sargent | Optically-regulated optical emission using colloidal quantum dot nanocrystals |
| US7773404B2 (en) | 2005-01-07 | 2010-08-10 | Invisage Technologies, Inc. | Quantum dot optical devices with enhanced gain and sensitivity and methods of making same |
| DE102004045210A1 (de) | 2004-09-17 | 2006-04-06 | Infineon Technologies Ag | Sensor-Anordnung und Verfahren zum Ermitteln eines Sensorereignisses |
| KR100678291B1 (ko) * | 2004-11-11 | 2007-02-02 | 삼성전자주식회사 | 나노입자를 이용한 수광소자 |
| CA2519608A1 (en) | 2005-01-07 | 2006-07-07 | Edward Sargent | Quantum dot-polymer nanocomposite photodetectors and photovoltaics |
| DE102005027245A1 (de) * | 2005-06-13 | 2006-12-21 | Siemens Ag | Schaltkreisanordnung |
| EP1894008A2 (de) * | 2005-06-17 | 2008-03-05 | Koninklijke Philips Electronics N.V. | Schneller magnetischer biosensor mit integrierter ankunftszeitmessung |
| WO2006134546A2 (en) * | 2005-06-17 | 2006-12-21 | Koninklijke Philips Electronics N.V. | Accurate magnetic biosensor |
| KR100714988B1 (ko) * | 2005-08-09 | 2007-05-09 | 삼성전자주식회사 | 산화막이 표면에 형성된 실리콘 구조물 표면을 이용한ｄｎａ 정제 방법 및 정제장치 |
| ITPD20050365A1 (it) * | 2005-12-14 | 2007-06-15 | Univ Degli Studi Trieste | Metodo e sistema di riconoscimento di pattern genetici |
| JP5220623B2 (ja) | 2006-03-16 | 2013-06-26 | ユニバーサル ナノセンサー テクノロジーズ インコーポレーテッド | 誘電率検出方法及びシステム |
| KR100777973B1 (ko) * | 2006-07-13 | 2007-11-29 | 한국표준과학연구원 | 다중선형전극 센서 유닛으로 이루어진 바이오센서 |
| EP1898211A1 (de) * | 2006-09-08 | 2008-03-12 | Université Catholique de Louvain | Isolierter Substratimpedanzwandler |
| EP2017609A1 (de) * | 2007-07-18 | 2009-01-21 | Université Catholique de Louvain | Verfahren und Vorrichtung zum hochempfindlichen quantitativen Nachweis von chemischen/biologischen Molekülen |
| US8159347B2 (en) * | 2008-09-25 | 2012-04-17 | General Electric Company | Sensors having gap based sensing devices and methods of making and using the same |
| EP2182359B1 (de) * | 2008-10-30 | 2015-03-04 | Sysmex Corporation | Verfahren zur analytdetektion |
| WO2010099618A1 (en) | 2009-03-04 | 2010-09-10 | Al-Amin Dhirani | Conductance detection system and method |
| US8744568B2 (en) * | 2009-12-22 | 2014-06-03 | Boston Scientific Scimed, Inc. | Medical device with electroactive polymer powered by photovoltaic cell |
| JP2011232328A (ja) * | 2010-04-09 | 2011-11-17 | Hitachi Ltd | 生体物質検出アレイ、計測装置および計測方法 |
| KR20110128754A (ko) * | 2010-05-24 | 2011-11-30 | 한국생명공학연구원 | 극미량 시료 검출용 전기 바이오센서 |
| CN102888454B (zh) * | 2011-09-13 | 2015-04-22 | 中国水产科学研究院黄海水产研究所 | 非接触式基因扩增电化学快速检测方法 |
| US8986523B2 (en) | 2012-01-19 | 2015-03-24 | International Business Machines Corporation | Biosensor capacitor |
| US9382579B2 (en) * | 2012-03-02 | 2016-07-05 | Nokomis, Inc. | DNA/nanoparticle complex enhanced radio frequency transponder: structure of mark for detecting hybridization state and authenticating and tracking articles, method of preparing the same, and method of authenticating the same |
| CN106164659A (zh) * | 2014-03-07 | 2016-11-23 | 得克萨斯州大学系统董事会 | 用于分子分析的三电极设备和方法 |
| US10004433B2 (en) * | 2014-07-07 | 2018-06-26 | Verily Life Sciences Llc | Electrochemical sensor chip |
| CA3021580A1 (en) | 2015-06-25 | 2016-12-29 | Barry L. Merriman | Biomolecular sensors and methods |
| KR101754239B1 (ko) * | 2015-12-28 | 2017-07-06 | 한국과학기술연구원 | 수용체와 표적 생체물질의 반응을 이용한 교차 전극 바이오센서 |
| CA3050062A1 (en) | 2016-01-14 | 2017-07-20 | Roswell Biotechnologies, Inc. | Molecular sensors and related methods |
| EP3408219B1 (de) | 2016-01-28 | 2022-08-17 | Roswell Biotechnologies, Inc | Massiv parallele dna-sequenzierungsvorrichtung |
| JP7280590B2 (ja) | 2016-01-28 | 2023-05-24 | ロズウェル バイオテクノロジーズ，インコーポレイテッド | 大スケールの分子電子工学センサアレイを使用する被分析物を測定するための方法および装置 |
| US10737263B2 (en) | 2016-02-09 | 2020-08-11 | Roswell Biotechnologies, Inc. | Electronic label-free DNA and genome sequencing |
| US10597767B2 (en) | 2016-02-22 | 2020-03-24 | Roswell Biotechnologies, Inc. | Nanoparticle fabrication |
| US9829456B1 (en) | 2016-07-26 | 2017-11-28 | Roswell Biotechnologies, Inc. | Method of making a multi-electrode structure usable in molecular sensing devices |
| US10585094B2 (en) * | 2016-09-01 | 2020-03-10 | The Governors Of The University Of Alberta | Devices and methods for nanoparticle enhanced impedance-based molecular sensing |
| EP3339833B1 (de) * | 2016-12-22 | 2021-11-10 | Heraeus Nexensos GmbH | Sensor, insbesondere russsensor, verfahren zur herstellung eines sensors, insbesondere eines russsensors, und verwendung |
| WO2018132457A1 (en) | 2017-01-10 | 2018-07-19 | Roswell Biotechnologies, Inc. | Methods and systems for dna data storage |
| CN110520517A (zh) | 2017-01-19 | 2019-11-29 | 罗斯威尔生命技术公司 | 包括二维层材料的固态测序装置 |
| US10508296B2 (en) | 2017-04-25 | 2019-12-17 | Roswell Biotechnologies, Inc. | Enzymatic circuits for molecular sensors |
| KR102879682B1 (ko) | 2017-04-25 | 2025-10-30 | 로스웰 엠이 아이엔씨. | 분자 센서들을 위한 효소 회로들 |
| CA3057155A1 (en) | 2017-05-09 | 2018-11-15 | Roswell Biotechnologies, Inc. | Binding probe circuits for molecular sensors |
| EP3676389A4 (de) | 2017-08-30 | 2021-06-02 | Roswell Biotechnologies, Inc | Prozessive enzymatische molekulare elektronische sensoren zur speicherung von dna-daten |
| EP3694990A4 (de) | 2017-10-10 | 2022-06-15 | Roswell Biotechnologies, Inc. | Verfahren, vorrichtung und systeme zur amplikationsfreien dna-datenspeicherung |
| CN109142462B (zh) * | 2018-06-22 | 2021-05-04 | 思贝科斯(北京)科技有限公司 | 电导探针及其制造方法 |
| US11471789B2 (en) | 2018-07-12 | 2022-10-18 | Abb Schweiz Ag | Material phase with electrical lead |
| US11247165B2 (en) * | 2018-07-12 | 2022-02-15 | Abb Schweiz Ag | Material phase between conductive layers |
| CN113994013A (zh) | 2019-04-12 | 2022-01-28 | 罗斯威尔生命技术公司 | 用于分子电子学传感器的多环芳族桥 |
| WO2021045900A1 (en) | 2019-09-06 | 2021-03-11 | Roswell Biotechnologies, Inc. | Methods of fabricating nanoscale structures usable in molecular sensors and other devices |
| KR102286263B1 (ko) * | 2019-10-23 | 2021-08-04 | 가천대학교 산학협력단 | 나노소재를 이용한 정전용량형 화학센서 및 그의 제조방법 |
| GB202003649D0 (en) * | 2020-03-13 | 2020-04-29 | Imperial College Innovations Ltd | Cleanroom-free integrated trimdol silicon transducer for genetic detection of pathogens |
| US20240006756A1 (en) * | 2020-11-27 | 2024-01-04 | Nokia Shanghai Bell Co., Ltd. | Decoupling apparatus, a radiation unit and antenna |
| WO2024101320A1 (ja) * | 2022-11-07 | 2024-05-16 | 日本精工株式会社 | 測定方法、測定システム、およびプログラム |
| EP4474808A1 (de) * | 2023-06-07 | 2024-12-11 | ETH Zurich | Kapazitive mikroelektrodenvorrichtung zur erfassung einer biologischen aktivität in einer probe und verfahren zur verwendung solch einer mikroelektrodenvorrichtung |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS621967A (ja) | 1985-06-25 | 1987-01-07 | 松下電工株式会社 | 屋根の軒先瓦とけらば瓦との交差部の構造 |
| JPS6219767A (ja) * | 1985-07-19 | 1987-01-28 | Hitachi Ltd | パタ−ン検出型ｄｎａ分離検出装置 |
| AU4647589A (en) | 1988-11-10 | 1990-05-28 | Midwest Research Technologies, Inc. | Method for electrical detection of a binding reaction |
| US5156810A (en) | 1989-06-15 | 1992-10-20 | Biocircuits Corporation | Biosensors employing electrical, optical and mechanical signals |
| US5965452A (en) * | 1996-07-09 | 1999-10-12 | Nanogen, Inc. | Multiplexed active biologic array |
| WO1997021094A1 (en) * | 1995-12-01 | 1997-06-12 | Innogenetics N.V. | Impedimetric detection system and method of production thereof |
| US5917264A (en) * | 1996-09-05 | 1999-06-29 | Nagano Keiki Co Ltd | Electrostatic capacitance type transducer and method for producing the same |
| US5922537A (en) * | 1996-11-08 | 1999-07-13 | N.o slashed.AB Immunoassay, Inc. | Nanoparticles biosensor |
| EP1019715B1 (de) * | 1997-08-08 | 2005-01-26 | California Institute Of Technology | Techniken und systeme zum nachweis von analyten |
| US6495892B2 (en) * | 1997-08-08 | 2002-12-17 | California Institute Of Technology | Techniques and systems for analyte detection |
| CA2300268A1 (en) * | 1997-08-12 | 1999-02-18 | Robert D. Macphee | Electrochemical reporter system for detecting analytical immunoassay and molecular biology procedures |
| US20020166764A1 (en) * | 1997-08-12 | 2002-11-14 | University Of Southern California | Electrochemical sensor devices and methods for fast, reliable, and sensitive detection and quantitation of analytes |
| BE1011776A3 (nl) * | 1998-03-06 | 2000-01-11 | Vito | Sensor voor toepassing in metaalsmelten. |
| JP4482228B2 (ja) * | 1998-04-09 | 2010-06-16 | カリフォルニア・インスティテュート・オブ・テクノロジー | アナライト検出のための電子技術 |
| US6236096B1 (en) * | 1998-10-06 | 2001-05-22 | National Science Council Of Republic Of China | Structure of a three-electrode capacitive pressure sensor |
| DE60000583T3 (de) * | 1999-05-19 | 2009-04-30 | Eppendorf Array Technologies | Verfahren zur identifizierung und/oder quantifizierung einer zielverbindung |
| US20030096321A1 (en) * | 1999-05-19 | 2003-05-22 | Jose Remacle | Method for the identification and/or the quantification of a target compound obtained from a biological sample upon chips |
| US20010053522A1 (en) * | 2000-04-28 | 2001-12-20 | Fuji Photo Film Co., Ltd. | DNA chip and reactive electrode |
| JP2002131155A (ja) * | 2000-10-30 | 2002-05-09 | Denso Corp | 感圧抵抗センサ |
| JP2002174611A (ja) * | 2000-12-08 | 2002-06-21 | Matsushita Electric Ind Co Ltd | 免疫電極センサー |
| US20020096119A1 (en) * | 2001-01-23 | 2002-07-25 | Kolozsvari Kevin L. | Pet Chair |
| US7531136B2 (en) * | 2001-11-26 | 2009-05-12 | Sony Deutschland Gmbh | Chemical sensor |
| EP1376111A1 (de) | 2002-06-24 | 2004-01-02 | Universite Catholique De Louvain | Verfahren und Vorrichtung für die hochempfindliche Bestimmung von DNA und anderen Testsubstanzen |
| JP5220623B2 (ja) * | 2006-03-16 | 2013-06-26 | ユニバーサル ナノセンサー テクノロジーズ インコーポレーテッド | 誘電率検出方法及びシステム |
| EP1898211A1 (de) * | 2006-09-08 | 2008-03-12 | Université Catholique de Louvain | Isolierter Substratimpedanzwandler |
-
2002
- 2002-06-24 EP EP02447122A patent/EP1376111A1/de not_active Withdrawn
-
2003
- 2003-06-24 DE DE60318313T patent/DE60318313T2/de not_active Expired - Lifetime
- 2003-06-24 WO PCT/BE2003/000109 patent/WO2004001403A1/en not_active Ceased
- 2003-06-24 US US10/519,014 patent/US7943394B2/en not_active Expired - Fee Related
- 2003-06-24 EP EP03760533A patent/EP1516174B1/de not_active Expired - Lifetime
- 2003-06-24 AT AT03760533T patent/ATE382147T1/de not_active IP Right Cessation
- 2003-06-24 AU AU2003243843A patent/AU2003243843A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE60318313T2 (de) | 2008-12-11 |
| US7943394B2 (en) | 2011-05-17 |
| AU2003243843A1 (en) | 2004-01-06 |
| WO2004001403A1 (en) | 2003-12-31 |
| EP1516174A1 (de) | 2005-03-23 |
| EP1516174B1 (de) | 2007-12-26 |
| DE60318313D1 (de) | 2008-02-07 |
| US20050227373A1 (en) | 2005-10-13 |
| EP1376111A1 (de) | 2004-01-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |