ATE382147T1 - Verfahren und einrichtung zur hochempfindlichen detektion der anwesenheit von dna und weitere sonden - Google Patents
Verfahren und einrichtung zur hochempfindlichen detektion der anwesenheit von dna und weitere sondenInfo
- Publication number
- ATE382147T1 ATE382147T1 AT03760533T AT03760533T ATE382147T1 AT E382147 T1 ATE382147 T1 AT E382147T1 AT 03760533 T AT03760533 T AT 03760533T AT 03760533 T AT03760533 T AT 03760533T AT E382147 T1 ATE382147 T1 AT E382147T1
- Authority
- AT
- Austria
- Prior art keywords
- target sample
- capacitive sensor
- binding site
- substrate
- conductive
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
- G01N27/22—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating capacitance
- G01N27/221—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating capacitance by investigating the dielectric properties
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
- G01N27/22—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating capacitance
- G01N27/226—Construction of measuring vessels; Electrodes therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
- G01N33/5438—Electrodes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/145555—Hetero-N
- Y10T436/147777—Plural nitrogen in the same ring [e.g., barbituates, creatinine, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/16—Phosphorus containing
- Y10T436/163333—Organic [e.g., chemical warfare agents, insecticides, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/17—Nitrogen containing
- Y10T436/173845—Amine and quaternary ammonium
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Electrochemistry (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02447122A EP1376111A1 (de) | 2002-06-24 | 2002-06-24 | Verfahren und Vorrichtung für die hochempfindliche Bestimmung von DNA und anderen Testsubstanzen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE382147T1 true ATE382147T1 (de) | 2008-01-15 |
Family
ID=29717039
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03760533T ATE382147T1 (de) | 2002-06-24 | 2003-06-24 | Verfahren und einrichtung zur hochempfindlichen detektion der anwesenheit von dna und weitere sonden |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7943394B2 (de) |
| EP (2) | EP1376111A1 (de) |
| AT (1) | ATE382147T1 (de) |
| AU (1) | AU2003243843A1 (de) |
| DE (1) | DE60318313T2 (de) |
| WO (1) | WO2004001403A1 (de) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0114399D0 (en) * | 2001-06-13 | 2001-08-08 | Univ Liverpool | Substrates, biomaterials and methods |
| EP1376111A1 (de) | 2002-06-24 | 2004-01-02 | Universite Catholique De Louvain | Verfahren und Vorrichtung für die hochempfindliche Bestimmung von DNA und anderen Testsubstanzen |
| CA2834041C (en) * | 2003-12-31 | 2017-05-16 | President And Fellows Of Harvard College | Assay device and method |
| US7742322B2 (en) | 2005-01-07 | 2010-06-22 | Invisage Technologies, Inc. | Electronic and optoelectronic devices with quantum dot films |
| WO2005101530A1 (en) | 2004-04-19 | 2005-10-27 | Edward Sargent | Optically-regulated optical emission using colloidal quantum dot nanocrystals |
| US7746681B2 (en) | 2005-01-07 | 2010-06-29 | Invisage Technologies, Inc. | Methods of making quantum dot films |
| US7773404B2 (en) | 2005-01-07 | 2010-08-10 | Invisage Technologies, Inc. | Quantum dot optical devices with enhanced gain and sensitivity and methods of making same |
| DE102004045210A1 (de) | 2004-09-17 | 2006-04-06 | Infineon Technologies Ag | Sensor-Anordnung und Verfahren zum Ermitteln eines Sensorereignisses |
| KR100678291B1 (ko) * | 2004-11-11 | 2007-02-02 | 삼성전자주식회사 | 나노입자를 이용한 수광소자 |
| CA2519608A1 (en) | 2005-01-07 | 2006-07-07 | Edward Sargent | Quantum dot-polymer nanocomposite photodetectors and photovoltaics |
| DE102005027245A1 (de) * | 2005-06-13 | 2006-12-21 | Siemens Ag | Schaltkreisanordnung |
| US20080206892A1 (en) * | 2005-06-17 | 2008-08-28 | Koninklijke Philips Electronics, N.V. | Rapid Magnetic Biosensor With Integrated Arrival Time Measuremnt |
| CN101198870A (zh) * | 2005-06-17 | 2008-06-11 | 皇家飞利浦电子股份有限公司 | 精密磁性生物传感器 |
| KR100714988B1 (ko) * | 2005-08-09 | 2007-05-09 | 삼성전자주식회사 | 산화막이 표면에 형성된 실리콘 구조물 표면을 이용한ｄｎａ 정제 방법 및 정제장치 |
| ITPD20050365A1 (it) * | 2005-12-14 | 2007-06-15 | Univ Degli Studi Trieste | Metodo e sistema di riconoscimento di pattern genetici |
| KR20090033166A (ko) | 2006-03-16 | 2009-04-01 | 알-아민 디라니 | 유전 감지 방법 및 시스템 |
| KR100777973B1 (ko) * | 2006-07-13 | 2007-11-29 | 한국표준과학연구원 | 다중선형전극 센서 유닛으로 이루어진 바이오센서 |
| EP1898211A1 (de) * | 2006-09-08 | 2008-03-12 | Université Catholique de Louvain | Isolierter Substratimpedanzwandler |
| EP2017609A1 (de) * | 2007-07-18 | 2009-01-21 | Université Catholique de Louvain | Verfahren und Vorrichtung zum hochempfindlichen quantitativen Nachweis von chemischen/biologischen Molekülen |
| US8159347B2 (en) * | 2008-09-25 | 2012-04-17 | General Electric Company | Sensors having gap based sensing devices and methods of making and using the same |
| EP2182359B1 (de) * | 2008-10-30 | 2015-03-04 | Sysmex Corporation | Verfahren zur analytdetektion |
| EP2404166A4 (de) | 2009-03-04 | 2013-03-27 | Al-Amin Dhirani | System und verfahren zur erkennung der leitfähigkeit |
| US8744568B2 (en) * | 2009-12-22 | 2014-06-03 | Boston Scientific Scimed, Inc. | Medical device with electroactive polymer powered by photovoltaic cell |
| JP2011232328A (ja) * | 2010-04-09 | 2011-11-17 | Hitachi Ltd | 生体物質検出アレイ、計測装置および計測方法 |
| KR20110128754A (ko) * | 2010-05-24 | 2011-11-30 | 한국생명공학연구원 | 극미량 시료 검출용 전기 바이오센서 |
| CN102888454B (zh) * | 2011-09-13 | 2015-04-22 | 中国水产科学研究院黄海水产研究所 | 非接触式基因扩增电化学快速检测方法 |
| US8986523B2 (en) | 2012-01-19 | 2015-03-24 | International Business Machines Corporation | Biosensor capacitor |
| US9382579B2 (en) * | 2012-03-02 | 2016-07-05 | Nokomis, Inc. | DNA/nanoparticle complex enhanced radio frequency transponder: structure of mark for detecting hybridization state and authenticating and tracking articles, method of preparing the same, and method of authenticating the same |
| SG11201607411RA (en) | 2014-03-07 | 2016-10-28 | Univ Texas | Tri-electrode apparatus and methods for molecular analysis |
| US10004433B2 (en) * | 2014-07-07 | 2018-06-26 | Verily Life Sciences Llc | Electrochemical sensor chip |
| KR102713216B1 (ko) | 2015-06-25 | 2024-10-02 | 로스웰 엠이 아이엔씨. | 바이오분자 센서들 및 방법들 |
| KR101754239B1 (ko) * | 2015-12-28 | 2017-07-06 | 한국과학기술연구원 | 수용체와 표적 생체물질의 반응을 이용한 교차 전극 바이오센서 |
| JP7109785B2 (ja) | 2016-01-14 | 2022-08-01 | ロズウェル バイオテクノロジーズ，インコーポレイテッド | 分子センサーおよび関連方法 |
| US10712334B2 (en) | 2016-01-28 | 2020-07-14 | Roswell Biotechnologies, Inc. | Massively parallel DNA sequencing apparatus |
| EP3408220A4 (de) | 2016-01-28 | 2019-09-04 | Roswell Biotechnologies, Inc | Verfahren und vorrichtung zum messen von analyten unter verwendung von grossskaligen molekularelektronischen sensorarrays |
| US10737263B2 (en) | 2016-02-09 | 2020-08-11 | Roswell Biotechnologies, Inc. | Electronic label-free DNA and genome sequencing |
| US10597767B2 (en) | 2016-02-22 | 2020-03-24 | Roswell Biotechnologies, Inc. | Nanoparticle fabrication |
| US9829456B1 (en) | 2016-07-26 | 2017-11-28 | Roswell Biotechnologies, Inc. | Method of making a multi-electrode structure usable in molecular sensing devices |
| US10585094B2 (en) * | 2016-09-01 | 2020-03-10 | The Governors Of The University Of Alberta | Devices and methods for nanoparticle enhanced impedance-based molecular sensing |
| EP3339833B1 (de) * | 2016-12-22 | 2021-11-10 | Heraeus Nexensos GmbH | Sensor, insbesondere russsensor, verfahren zur herstellung eines sensors, insbesondere eines russsensors, und verwendung |
| CN110431148A (zh) | 2017-01-10 | 2019-11-08 | 罗斯威尔生命技术公司 | 用于dna数据存储的方法和系统 |
| KR102685937B1 (ko) | 2017-01-19 | 2024-07-17 | 로스웰 엠이 아이엔씨. | 2차원 레이어 재료를 포함하는 솔리드 스테이트 시퀀싱 디바이스들 |
| KR102692957B1 (ko) | 2017-04-25 | 2024-08-06 | 로스웰 엠이 아이엔씨. | 분자 센서들을 위한 효소 회로들 |
| CN110651182B (zh) | 2017-05-09 | 2022-12-30 | 罗斯威尔生命技术公司 | 用于分子传感器的结合探针电路 |
| EP3676389A4 (de) | 2017-08-30 | 2021-06-02 | Roswell Biotechnologies, Inc | Prozessive enzymatische molekulare elektronische sensoren zur speicherung von dna-daten |
| WO2019075100A1 (en) | 2017-10-10 | 2019-04-18 | Roswell Biotechnologies, Inc. | METHODS, APPARATUS AND SYSTEMS FOR STORING DNA DATA WITHOUT AMPLIFICATION |
| CN109142462B (zh) * | 2018-06-22 | 2021-05-04 | 思贝科斯(北京)科技有限公司 | 电导探针及其制造方法 |
| US11247165B2 (en) | 2018-07-12 | 2022-02-15 | Abb Schweiz Ag | Material phase between conductive layers |
| US11471789B2 (en) * | 2018-07-12 | 2022-10-18 | Abb Schweiz Ag | Material phase with electrical lead |
| US12504396B2 (en) | 2019-04-12 | 2025-12-23 | SemiconBio | Polycyclic aromatic bridges for molecular electronic sensors |
| WO2021045900A1 (en) | 2019-09-06 | 2021-03-11 | Roswell Biotechnologies, Inc. | Methods of fabricating nanoscale structures usable in molecular sensors and other devices |
| KR102286263B1 (ko) * | 2019-10-23 | 2021-08-04 | 가천대학교 산학협력단 | 나노소재를 이용한 정전용량형 화학센서 및 그의 제조방법 |
| GB202003649D0 (en) * | 2020-03-13 | 2020-04-29 | Imperial College Innovations Ltd | Cleanroom-free integrated trimdol silicon transducer for genetic detection of pathogens |
| WO2022110061A1 (en) * | 2020-11-27 | 2022-06-02 | Rfs Radio Frequency Systems (Shanghai) Co., Ltd. | Decoupling apparatus, a radiation unit and antenna |
| US12623218B2 (en) | 2021-12-17 | 2026-05-12 | Hidaca Ltd | Well array device, system and methods of use thereof |
| JPWO2024101320A1 (de) * | 2022-11-07 | 2024-05-16 | ||
| EP4474808A1 (de) * | 2023-06-07 | 2024-12-11 | ETH Zurich | Kapazitive mikroelektrodenvorrichtung zur erfassung einer biologischen aktivität in einer probe und verfahren zur verwendung solch einer mikroelektrodenvorrichtung |
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| JPS621967A (ja) | 1985-06-25 | 1987-01-07 | 松下電工株式会社 | 屋根の軒先瓦とけらば瓦との交差部の構造 |
| JPS6219767A (ja) * | 1985-07-19 | 1987-01-28 | Hitachi Ltd | パタ−ン検出型ｄｎａ分離検出装置 |
| CA2002660A1 (en) | 1988-11-10 | 1990-05-10 | Susan J. Mroczkowski | Method for electrical detection of a binding reaction |
| US5156810A (en) | 1989-06-15 | 1992-10-20 | Biocircuits Corporation | Biosensors employing electrical, optical and mechanical signals |
| US5965452A (en) * | 1996-07-09 | 1999-10-12 | Nanogen, Inc. | Multiplexed active biologic array |
| US6440662B1 (en) * | 1995-12-01 | 2002-08-27 | Innogenetics N.V. | Impedimetric detection system and method of production thereof |
| US5917264A (en) * | 1996-09-05 | 1999-06-29 | Nagano Keiki Co Ltd | Electrostatic capacitance type transducer and method for producing the same |
| US5922537A (en) * | 1996-11-08 | 1999-07-13 | N.o slashed.AB Immunoassay, Inc. | Nanoparticles biosensor |
| WO1999008105A1 (en) * | 1997-08-08 | 1999-02-18 | California Institute Of Technology | Techniques and systems for analyte detection |
| US6495892B2 (en) * | 1997-08-08 | 2002-12-17 | California Institute Of Technology | Techniques and systems for analyte detection |
| JP2001512691A (ja) * | 1997-08-12 | 2001-08-28 | ユニバーシティ・オブ・サザン・カリフォルニア | イムノアッセイ分析および分子生物学的な過程を調べるための電気化学的レポーターシステム |
| US20020166764A1 (en) * | 1997-08-12 | 2002-11-14 | University Of Southern California | Electrochemical sensor devices and methods for fast, reliable, and sensitive detection and quantitation of analytes |
| BE1011776A3 (nl) * | 1998-03-06 | 2000-01-11 | Vito | Sensor voor toepassing in metaalsmelten. |
| AU747878B2 (en) | 1998-04-09 | 2002-05-30 | California Institute Of Technology | Electronic techniques for analyte detection |
| US6236096B1 (en) * | 1998-10-06 | 2001-05-22 | National Science Council Of Republic Of China | Structure of a three-electrode capacitive pressure sensor |
| AU779752B2 (en) * | 1999-05-19 | 2005-02-10 | Eppendorf Array Technologies S.A. | Method for the identification and/or the quantification of a target compound |
| US20030096321A1 (en) * | 1999-05-19 | 2003-05-22 | Jose Remacle | Method for the identification and/or the quantification of a target compound obtained from a biological sample upon chips |
| US20010053522A1 (en) * | 2000-04-28 | 2001-12-20 | Fuji Photo Film Co., Ltd. | DNA chip and reactive electrode |
| JP2002131155A (ja) * | 2000-10-30 | 2002-05-09 | Denso Corp | 感圧抵抗センサ |
| JP2002174611A (ja) * | 2000-12-08 | 2002-06-21 | Matsushita Electric Ind Co Ltd | 免疫電極センサー |
| US20020096119A1 (en) * | 2001-01-23 | 2002-07-25 | Kolozsvari Kevin L. | Pet Chair |
| US7531136B2 (en) * | 2001-11-26 | 2009-05-12 | Sony Deutschland Gmbh | Chemical sensor |
| EP1376111A1 (de) | 2002-06-24 | 2004-01-02 | Universite Catholique De Louvain | Verfahren und Vorrichtung für die hochempfindliche Bestimmung von DNA und anderen Testsubstanzen |
| KR20090033166A (ko) * | 2006-03-16 | 2009-04-01 | 알-아민 디라니 | 유전 감지 방법 및 시스템 |
| EP1898211A1 (de) * | 2006-09-08 | 2008-03-12 | Université Catholique de Louvain | Isolierter Substratimpedanzwandler |
-
2002
- 2002-06-24 EP EP02447122A patent/EP1376111A1/de not_active Withdrawn
-
2003
- 2003-06-24 DE DE60318313T patent/DE60318313T2/de not_active Expired - Lifetime
- 2003-06-24 EP EP03760533A patent/EP1516174B1/de not_active Expired - Lifetime
- 2003-06-24 WO PCT/BE2003/000109 patent/WO2004001403A1/en not_active Ceased
- 2003-06-24 AU AU2003243843A patent/AU2003243843A1/en not_active Abandoned
- 2003-06-24 AT AT03760533T patent/ATE382147T1/de not_active IP Right Cessation
- 2003-06-24 US US10/519,014 patent/US7943394B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1516174B1 (de) | 2007-12-26 |
| DE60318313T2 (de) | 2008-12-11 |
| US7943394B2 (en) | 2011-05-17 |
| US20050227373A1 (en) | 2005-10-13 |
| EP1516174A1 (de) | 2005-03-23 |
| EP1376111A1 (de) | 2004-01-02 |
| DE60318313D1 (de) | 2008-02-07 |
| WO2004001403A1 (en) | 2003-12-31 |
| AU2003243843A1 (en) | 2004-01-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |