|
WO1994003624A1
(en)
*
|
1992-08-04 |
1994-02-17 |
Auerbach Jeffrey I |
Methods for the isothermal amplification of nucleic acid molecules
|
|
US6261808B1
(en)
*
|
1992-08-04 |
2001-07-17 |
Replicon, Inc. |
Amplification of nucleic acid molecules via circular replicons
|
|
US6593086B2
(en)
|
1996-05-20 |
2003-07-15 |
Mount Sinai School Of Medicine Of New York University |
Nucleic acid amplification methods
|
|
AU714486B2
(en)
|
1995-11-21 |
2000-01-06 |
Yale University |
Unimolecular segment amplification and detection
|
|
US5854033A
(en)
*
|
1995-11-21 |
1998-12-29 |
Yale University |
Rolling circle replication reporter systems
|
|
JP2002503954A
(ja)
|
1997-04-01 |
2002-02-05 |
グラクソ、グループ、リミテッド |
核酸増幅法
|
|
US6124120A
(en)
*
|
1997-10-08 |
2000-09-26 |
Yale University |
Multiple displacement amplification
|
|
US8445664B2
(en)
*
|
1998-06-24 |
2013-05-21 |
Enzo Diagnostics, Inc. |
Kits for amplifying and detecting nucleic acid sequences
|
|
US6743605B1
(en)
*
|
1998-06-24 |
2004-06-01 |
Enzo Life Sciences, Inc. |
Linear amplification of specific nucleic acid sequences
|
|
AU763890B2
(en)
*
|
1998-09-15 |
2003-07-31 |
Yale University |
Artificial long terminal repeat vectors
|
|
AR021833A1
(es)
|
1998-09-30 |
2002-08-07 |
Applied Research Systems |
Metodos de amplificacion y secuenciacion de acido nucleico
|
|
US6531302B1
(en)
*
|
1999-04-12 |
2003-03-11 |
Nanogen/Becton Dickinson Partnership |
Anchored strand displacement amplification on an electronically addressable microchip
|
|
US6326173B1
(en)
*
|
1999-04-12 |
2001-12-04 |
Nanogen/Becton Dickinson Partnership |
Electronically mediated nucleic acid amplification in NASBA
|
|
CA2369016A1
(en)
*
|
1999-04-12 |
2000-10-19 |
Nanogen/Becton Dickinson Partnership |
Amplification and separation of nucleic acid sequences using strand displacement amplification and bioelectronic microchip technology
|
|
US6238868B1
(en)
*
|
1999-04-12 |
2001-05-29 |
Nanogen/Becton Dickinson Partnership |
Multiplex amplification and separation of nucleic acid sequences using ligation-dependant strand displacement amplification and bioelectronic chip technology
|
|
US20030215821A1
(en)
*
|
1999-04-20 |
2003-11-20 |
Kevin Gunderson |
Detection of nucleic acid reactions on bead arrays
|
|
US20060275782A1
(en)
|
1999-04-20 |
2006-12-07 |
Illumina, Inc. |
Detection of nucleic acid reactions on bead arrays
|
|
US6921638B2
(en)
*
|
1999-06-25 |
2005-07-26 |
Amersham Biosciences Ab |
Hydrogel-based microarray signal amplification methods and devices therefor
|
|
US6692918B2
(en)
|
1999-09-13 |
2004-02-17 |
Nugen Technologies, Inc. |
Methods and compositions for linear isothermal amplification of polynucleotide sequences
|
|
MXPA02002656A
(es)
|
1999-09-13 |
2003-10-14 |
Nugen Technologies Inc |
Metodos y composiciones para la ampliacion lineal isotermica de secuencias de polinucleotidos.
|
|
US6221600B1
(en)
*
|
1999-10-08 |
2001-04-24 |
Board Of Regents, The University Of Texas System |
Combinatorial oligonucleotide PCR: a method for rapid, global expression analysis
|
|
US7611869B2
(en)
|
2000-02-07 |
2009-11-03 |
Illumina, Inc. |
Multiplexed methylation detection methods
|
|
US8076063B2
(en)
|
2000-02-07 |
2011-12-13 |
Illumina, Inc. |
Multiplexed methylation detection methods
|
|
EP1990428B1
(de)
*
|
2000-02-07 |
2010-12-22 |
Illumina, Inc. |
Nukleinsäuredetektionsverfahren mit universellem Priming
|
|
US7955794B2
(en)
|
2000-09-21 |
2011-06-07 |
Illumina, Inc. |
Multiplex nucleic acid reactions
|
|
US7582420B2
(en)
*
|
2001-07-12 |
2009-09-01 |
Illumina, Inc. |
Multiplex nucleic acid reactions
|
|
US7205129B1
(en)
|
2000-02-28 |
2007-04-17 |
Qiagen Gmbh |
Method for reducing artifacts in nucleic acid amplification
|
|
US7455966B1
(en)
*
|
2000-05-01 |
2008-11-25 |
Science Applications International Corporation |
System and method for detecting a biological entity in a water sample
|
|
US20020120409A1
(en)
*
|
2000-05-19 |
2002-08-29 |
Affymetrix, Inc. |
Methods for gene expression analysis
|
|
US6828098B2
(en)
|
2000-05-20 |
2004-12-07 |
The Regents Of The University Of Michigan |
Method of producing a DNA library using positional amplification based on the use of adaptors and nick translation
|
|
US7435541B2
(en)
*
|
2000-05-23 |
2008-10-14 |
Sequenom, Inc. |
Restriction enzyme genotyping
|
|
EP1356094B1
(de)
|
2000-06-26 |
2010-01-13 |
Nugen Technologies, Inc. |
Methoden und zusammensetzungen zur auf transkription basierenden vervielfältigung von nukleinsäuren
|
|
US7846733B2
(en)
|
2000-06-26 |
2010-12-07 |
Nugen Technologies, Inc. |
Methods and compositions for transcription-based nucleic acid amplification
|
|
US6323009B1
(en)
*
|
2000-06-28 |
2001-11-27 |
Molecular Staging, Inc. |
Multiply-primed amplification of nucleic acid sequences
|
|
US6562572B1
(en)
*
|
2000-09-27 |
2003-05-13 |
Mayo Foundation For Medical Education And Research |
Methods for amplifying nucleic acid sequences
|
|
AR031640A1
(es)
|
2000-12-08 |
2003-09-24 |
Applied Research Systems |
Amplificacion isotermica de acidos nucleicos en un soporte solido
|
|
WO2002048402A2
(en)
|
2000-12-13 |
2002-06-20 |
Nugen Technologies, Inc. |
Methods and compositions for generation of multiple copies of nucleic acid sequences and methods of detection thereof
|
|
US6635425B2
(en)
*
|
2001-01-05 |
2003-10-21 |
Molecular Staging, Inc. |
5′-thio phosphate directed ligation of oligonucleotides and use in detection of single nucleotide polymorphisms
|
|
WO2002072773A2
(en)
|
2001-03-09 |
2002-09-19 |
Nugen Technologies, Inc. |
Methods and compositions for amplification of rna sequences
|
|
JP4542312B2
(ja)
|
2001-03-09 |
2010-09-15 |
ニューゲン テクノロジーズ, インコーポレイテッド |
Rna配列の増幅のための方法および組成物
|
|
US6777187B2
(en)
*
|
2001-05-02 |
2004-08-17 |
Rubicon Genomics, Inc. |
Genome walking by selective amplification of nick-translate DNA library and amplification from complex mixtures of templates
|
|
US8137911B2
(en)
*
|
2001-05-22 |
2012-03-20 |
Cellscript, Inc. |
Preparation and use of single-stranded transcription substrates for synthesis of transcription products corresponding to target sequences
|
|
US20040197791A1
(en)
*
|
2001-06-29 |
2004-10-07 |
Makarov Vladimir L. |
Methods of using nick translate libraries for snp analysis
|
|
WO2003008624A2
(en)
*
|
2001-07-15 |
2003-01-30 |
Keck Graduate Institute |
Nucleic acid amplification using nicking agents
|
|
GB2378245A
(en)
|
2001-08-03 |
2003-02-05 |
Mats Nilsson |
Nucleic acid amplification method
|
|
US20030124549A1
(en)
*
|
2001-10-11 |
2003-07-03 |
Xerox Corporation |
Devices and methods for detecting genetic sequences
|
|
US6977148B2
(en)
*
|
2001-10-15 |
2005-12-20 |
Qiagen Gmbh |
Multiple displacement amplification
|
|
US7297485B2
(en)
*
|
2001-10-15 |
2007-11-20 |
Qiagen Gmbh |
Method for nucleic acid amplification that results in low amplification bias
|
|
US6617137B2
(en)
*
|
2001-10-15 |
2003-09-09 |
Molecular Staging Inc. |
Method of amplifying whole genomes without subjecting the genome to denaturing conditions
|
|
US6942972B2
(en)
|
2001-10-24 |
2005-09-13 |
Beckman Coulter, Inc. |
Efficient synthesis of protein-oligonucleotide conjugates
|
|
JP2005535283A
(ja)
*
|
2001-11-13 |
2005-11-24 |
ルビコン ゲノミクス インコーポレイテッド |
ランダムフラグメント化により生成されたdna分子を用いたdna増幅および配列決定
|
|
US7553619B2
(en)
|
2002-02-08 |
2009-06-30 |
Qiagen Gmbh |
Detection method using dissociated rolling circle amplification
|
|
US7629152B2
(en)
*
|
2002-03-01 |
2009-12-08 |
Integrated Dna Technologies, Inc. |
Methods for amplifying polymeric nucleic acids
|
|
AU2003213652A1
(en)
*
|
2002-03-01 |
2003-09-16 |
Integrated Dna Technologies, Inc. |
Polynomial amplification of nucleic acids
|
|
WO2003074740A1
(en)
*
|
2002-03-01 |
2003-09-12 |
Ravgen, Inc. |
Rapid analysis of variations in a genome
|
|
US6977162B2
(en)
*
|
2002-03-01 |
2005-12-20 |
Ravgen, Inc. |
Rapid analysis of variations in a genome
|
|
US7442506B2
(en)
*
|
2002-05-08 |
2008-10-28 |
Ravgen, Inc. |
Methods for detection of genetic disorders
|
|
US20070178478A1
(en)
*
|
2002-05-08 |
2007-08-02 |
Dhallan Ravinder S |
Methods for detection of genetic disorders
|
|
US7727720B2
(en)
*
|
2002-05-08 |
2010-06-01 |
Ravgen, Inc. |
Methods for detection of genetic disorders
|
|
US7176002B2
(en)
*
|
2002-05-16 |
2007-02-13 |
Applera Corporation |
Universal-tagged oligonucleotide primers and methods of use
|
|
US7115370B2
(en)
|
2002-06-05 |
2006-10-03 |
Capital Genomix, Inc. |
Combinatorial oligonucleotide PCR
|
|
WO2004013350A1
(en)
*
|
2002-08-01 |
2004-02-12 |
Novozymes A/S |
Methods for rolling circle amplification and signal trapping of libraries
|
|
US20050118616A1
(en)
*
|
2002-08-16 |
2005-06-02 |
Kawashima Tadashi R. |
Amplification of target nucleotide sequence without polymerase chain reaction
|
|
US20040081962A1
(en)
*
|
2002-10-23 |
2004-04-29 |
Caifu Chen |
Methods for synthesizing complementary DNA
|
|
US20040086892A1
(en)
*
|
2002-11-06 |
2004-05-06 |
Crothers Donald M. |
Universal tag assay
|
|
CN1324042C
(zh)
*
|
2002-11-08 |
2007-07-04 |
株式会社钟化 |
麦角甾醇的分离方法
|
|
CN1738914A
(zh)
|
2002-11-21 |
2006-02-22 |
震源技术公司 |
使用编码双链启动子一条链的引物的方法
|
|
US20040115644A1
(en)
*
|
2002-12-12 |
2004-06-17 |
Affymetrix, Inc. |
Methods of direct amplification and complexity reduction for genomic DNA
|
|
US20040115643A1
(en)
*
|
2002-12-12 |
2004-06-17 |
Lizardi Paul M. |
Thermodynamic equilibrium extension of primers
|
|
US20040121338A1
(en)
*
|
2002-12-19 |
2004-06-24 |
Alsmadi Osama A. |
Real-time detection of rolling circle amplification products
|
|
JP4886298B2
(ja)
*
|
2002-12-20 |
2012-02-29 |
キアゲン ゲゼルシャフト ミット ベシュレンクテル ハフツング |
核酸増幅
|
|
US9487823B2
(en)
*
|
2002-12-20 |
2016-11-08 |
Qiagen Gmbh |
Nucleic acid amplification
|
|
US7955795B2
(en)
*
|
2003-06-06 |
2011-06-07 |
Qiagen Gmbh |
Method of whole genome amplification with reduced artifact production
|
|
US6977153B2
(en)
|
2002-12-31 |
2005-12-20 |
Qiagen Gmbh |
Rolling circle amplification of RNA
|
|
EP1590470A4
(de)
*
|
2003-02-03 |
2006-09-27 |
Ge Healthcare Bio Sciences |
Cdna-amplifikation für expression-profiling
|
|
EP2365095A1
(de)
|
2003-02-26 |
2011-09-14 |
Callida Genomics, Inc. |
Zufallsarray DNA Analyse mittels Hybridisierung
|
|
EP1604040B1
(de)
|
2003-03-07 |
2010-10-13 |
Rubicon Genomics, Inc. |
Amplifikation und analyse von gesamtgenom- und gesamttranskriptom- bibliotheken, die durch ein dns-polymerisierungsverfahren produziert wurden
|
|
US8206913B1
(en)
|
2003-03-07 |
2012-06-26 |
Rubicon Genomics, Inc. |
Amplification and analysis of whole genome and whole transcriptome libraries generated by a DNA polymerization process
|
|
US8043834B2
(en)
|
2003-03-31 |
2011-10-25 |
Qiagen Gmbh |
Universal reagents for rolling circle amplification and methods of use
|
|
JP2006523465A
(ja)
|
2003-04-14 |
2006-10-19 |
ニューゲン テクノロジーズ, インコーポレイテッド |
ランダムにプライミングされる複合プライマーを用いる大規模増幅
|
|
US8150626B2
(en)
*
|
2003-05-15 |
2012-04-03 |
Illumina, Inc. |
Methods and compositions for diagnosing lung cancer with specific DNA methylation patterns
|
|
US20050026183A1
(en)
*
|
2003-05-15 |
2005-02-03 |
Jian-Bing Fan |
Methods and compositions for diagnosing conditions associated with specific DNA methylation patterns
|
|
US8150627B2
(en)
|
2003-05-15 |
2012-04-03 |
Illumina, Inc. |
Methods and compositions for diagnosing lung cancer with specific DNA methylation patterns
|
|
US20040248103A1
(en)
*
|
2003-06-04 |
2004-12-09 |
Feaver William John |
Proximity-mediated rolling circle amplification
|
|
CA2528577C
(en)
|
2003-06-20 |
2012-08-07 |
Illumina, Inc. |
Methods and compositions for whole genome amplification and genotyping
|
|
US20040259100A1
(en)
*
|
2003-06-20 |
2004-12-23 |
Illumina, Inc. |
Methods and compositions for whole genome amplification and genotyping
|
|
US20050181394A1
(en)
*
|
2003-06-20 |
2005-08-18 |
Illumina, Inc. |
Methods and compositions for whole genome amplification and genotyping
|
|
WO2005010159A2
(en)
*
|
2003-07-17 |
2005-02-03 |
Children's Hospital Medical Center |
Rolling circle amplification of micro-rna samples
|
|
WO2005012550A2
(en)
*
|
2003-07-31 |
2005-02-10 |
Diversa Corporation |
Screening methods and libraries of trace amounts of dna from uncultivated microorganisms
|
|
US20060141487A1
(en)
*
|
2004-01-26 |
2006-06-29 |
Applera Corporation |
Methods, compositions, and kits for amplifying and sequencing polynucleotides
|
|
EP2290106B1
(de)
*
|
2004-03-08 |
2018-01-03 |
Rubicon Genomics, Inc. |
Verfahren zur Erzeugung und Amplifizierung von DNS-Bibliotheken zur empfindlichen Erkennung und Untersuchung von DNS-Methylierung
|
|
WO2006000647A1
(en)
*
|
2004-06-29 |
2006-01-05 |
Wallac Oy |
Integrated non-homogeneous nucleic acid amplification and detection
|
|
US7776530B2
(en)
*
|
2004-06-29 |
2010-08-17 |
Wallac Oy |
Integrated nucleic acid analysis
|
|
US7700281B2
(en)
*
|
2004-06-30 |
2010-04-20 |
Usb Corporation |
Hot start nucleic acid amplification
|
|
US20060216724A1
(en)
*
|
2004-07-30 |
2006-09-28 |
Affymetrix, Inc. |
Methods for normalized amplification of nucleic acids
|
|
EP1784508B1
(de)
*
|
2004-08-09 |
2012-10-03 |
Generation Biotech, LLC |
Verfahren zur isolierung und amplifikation von nukleinsäuren
|
|
US7585626B1
(en)
*
|
2004-08-19 |
2009-09-08 |
Quest Diagnostics Investments Incorporated |
Methods for nucleic acid amplification
|
|
US7315019B2
(en)
*
|
2004-09-17 |
2008-01-01 |
Pacific Biosciences Of California, Inc. |
Arrays of optical confinements and uses thereof
|
|
US7170050B2
(en)
*
|
2004-09-17 |
2007-01-30 |
Pacific Biosciences Of California, Inc. |
Apparatus and methods for optical analysis of molecules
|
|
US20080305142A1
(en)
*
|
2004-12-11 |
2008-12-11 |
Cytogenix, Inc. |
Cell Free Biosynthesis of High-Quality Nucleic Acid and Uses Thereof
|
|
US20060134650A1
(en)
*
|
2004-12-21 |
2006-06-22 |
Illumina, Inc. |
Methylation-sensitive restriction enzyme endonuclease method of whole genome methylation analysis
|
|
CA2491067A1
(en)
|
2004-12-24 |
2006-06-24 |
Stichting Katholieke Universiteit |
Mrna rations in urinary sediments and/or urine as a prognostic marker for prostate cancer
|
|
EP1693468A1
(de)
|
2005-02-16 |
2006-08-23 |
Epigenomics AG |
Verfahren zur Bestimmung des Methylierungsmusters einer Polynukleinsäure
|
|
US7932027B2
(en)
*
|
2005-02-16 |
2011-04-26 |
Epigenomics Ag |
Method for determining the methylation pattern of a polynucleic acid
|
|
US8309303B2
(en)
|
2005-04-01 |
2012-11-13 |
Qiagen Gmbh |
Reverse transcription and amplification of RNA with simultaneous degradation of DNA
|
|
US7449297B2
(en)
|
2005-04-14 |
2008-11-11 |
Euclid Diagnostics Llc |
Methods of copying the methylation pattern of DNA during isothermal amplification and microarrays
|
|
WO2006113770A1
(en)
|
2005-04-15 |
2006-10-26 |
Epigenomics Ag |
A method for providing dna fragments derived from a remote sample
|
|
WO2006111784A1
(en)
*
|
2005-04-20 |
2006-10-26 |
Parco Tecnologico Padano Srl |
Method for enlarging the range of applicability of multiple displacement amplification of linear dna
|
|
JP5331476B2
(ja)
|
2005-06-15 |
2013-10-30 |
カリダ・ジェノミックス・インコーポレイテッド |
遺伝子解析および化学解析用の単分子アレイ
|
|
US20070020667A1
(en)
*
|
2005-06-30 |
2007-01-25 |
Ruff David W |
Methods and compositions for amplifying nucleic acids
|
|
ATE452993T1
(de)
|
2005-07-21 |
2010-01-15 |
Epigenomics Ag |
Verfahren zur quantifizierung methylierter dna
|
|
US9424392B2
(en)
|
2005-11-26 |
2016-08-23 |
Natera, Inc. |
System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals
|
|
US11111543B2
(en)
|
2005-07-29 |
2021-09-07 |
Natera, Inc. |
System and method for cleaning noisy genetic data and determining chromosome copy number
|
|
US11111544B2
(en)
|
2005-07-29 |
2021-09-07 |
Natera, Inc. |
System and method for cleaning noisy genetic data and determining chromosome copy number
|
|
WO2007018601A1
(en)
|
2005-08-02 |
2007-02-15 |
Rubicon Genomics, Inc. |
Compositions and methods for processing and amplification of dna, including using multiple enzymes in a single reaction
|
|
EP1924705A1
(de)
*
|
2005-08-02 |
2008-05-28 |
Rubicon Genomics, Inc. |
Isolierung von cpg-inseln durch thermische segregation und enzymatisches selektions-amplifikations-verfahren
|
|
WO2007019444A2
(en)
*
|
2005-08-05 |
2007-02-15 |
Euclid Diagnostics Llc |
Subtractive separation and amplification of non-ribosomal transcribed rna (nrrna)
|
|
WO2007030759A2
(en)
|
2005-09-07 |
2007-03-15 |
Nugen Technologies, Inc. |
Improved nucleic acid amplification procedure
|
|
EP1762627A1
(de)
|
2005-09-09 |
2007-03-14 |
Qiagen GmbH |
Verfahren zur Aktivierung einer Nukleinsäure für eine Polymerase-Reaktion
|
|
EP1934339B1
(de)
*
|
2005-10-06 |
2011-12-14 |
Lucigen Corporation |
Temperaturstabile virale polymerasen und verwendungsverfahren
|
|
US7960104B2
(en)
|
2005-10-07 |
2011-06-14 |
Callida Genomics, Inc. |
Self-assembled single molecule arrays and uses thereof
|
|
US20070092899A1
(en)
*
|
2005-10-21 |
2007-04-26 |
The Regents Of The University Of California |
Multiple displacement amplification with blocker DNA
|
|
AU2006339538A1
(en)
|
2005-11-08 |
2007-09-13 |
Euclid Diagnostics Llc |
Materials and methods for assaying for methylation of CpG islands associated with genes in the evaluation of cancer
|
|
JP4989493B2
(ja)
|
2006-01-20 |
2012-08-01 |
オリンパス株式会社 |
分子内プローブによる核酸配列の検出方法
|
|
US20080057499A1
(en)
*
|
2006-02-06 |
2008-03-06 |
Affymetrix, Inc. |
Methods for high specificity whole genome amplification and hybridization
|
|
CA2643700A1
(en)
*
|
2006-02-24 |
2007-11-22 |
Callida Genomics, Inc. |
High throughput genome sequencing on dna arrays
|
|
SG170028A1
(en)
*
|
2006-02-24 |
2011-04-29 |
Callida Genomics Inc |
High throughput genome sequencing on dna arrays
|
|
WO2007133682A2
(en)
*
|
2006-05-11 |
2007-11-22 |
Geneohm Sciences, Inc. |
100% sequence identity detection methods for variable genomes
|
|
US7833716B2
(en)
|
2006-06-06 |
2010-11-16 |
Gen-Probe Incorporated |
Tagged oligonucleotides and their use in nucleic acid amplification methods
|
|
WO2007147074A2
(en)
|
2006-06-14 |
2007-12-21 |
Living Microsystems, Inc. |
Use of highly parallel snp genotyping for fetal diagnosis
|
|
US20080050739A1
(en)
|
2006-06-14 |
2008-02-28 |
Roland Stoughton |
Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats
|
|
EP2589668A1
(de)
|
2006-06-14 |
2013-05-08 |
Verinata Health, Inc |
Analyse seltener Zellen mittels Probentrennung und DNA-Etiketten
|
|
US7501254B2
(en)
*
|
2006-07-20 |
2009-03-10 |
Ghc Technologies, Inc. |
Methods and compositions for amplification and capture of nucleic acid sequences
|
|
EP2520935A3
(de)
|
2006-08-09 |
2013-02-13 |
Homestead Clinical Corporation |
Organspezifische Proteine und Verfahren zu deren Verwendung
|
|
US8420798B2
(en)
*
|
2006-09-01 |
2013-04-16 |
Ventana Medical Systems, Inc. |
Method for producing nucleic acid probes
|
|
US8252558B2
(en)
|
2006-10-09 |
2012-08-28 |
Oxitec Limited |
Methods for amplifying and detecting nucleic acid sequences
|
|
US20100184152A1
(en)
*
|
2006-10-23 |
2010-07-22 |
Vladislav Sandler |
Target-oriented whole genome amplification of nucleic acids
|
|
US20080096258A1
(en)
*
|
2006-10-24 |
2008-04-24 |
Christian Korfhage |
Rolling circle amplification of circular genomes
|
|
WO2008063378A2
(en)
|
2006-11-01 |
2008-05-29 |
Ventana Medical Systems, Inc. |
Haptens, hapten conjugates, compositions thereof and method for their preparation and use
|
|
US20080221832A1
(en)
*
|
2006-11-09 |
2008-09-11 |
Complete Genomics, Inc. |
Methods for computing positional base probabilities using experminentals base value distributions
|
|
WO2008093098A2
(en)
*
|
2007-02-02 |
2008-08-07 |
Illumina Cambridge Limited |
Methods for indexing samples and sequencing multiple nucleotide templates
|
|
US7682789B2
(en)
*
|
2007-05-04 |
2010-03-23 |
Ventana Medical Systems, Inc. |
Method for quantifying biomolecules conjugated to a nanoparticle
|
|
JP2010528285A
(ja)
|
2007-05-23 |
2010-08-19 |
ベンタナ・メデイカル・システムズ・インコーポレーテツド |
免疫組織化学およびinsituハイブリダーゼーションのためのポリマー担体
|
|
US9598724B2
(en)
|
2007-06-01 |
2017-03-21 |
Ibis Biosciences, Inc. |
Methods and compositions for multiple displacement amplification of nucleic acids
|
|
RU2414510C2
(ru)
*
|
2007-06-14 |
2011-03-20 |
Институт биохимии и генетики Уфимского научного центра РАН |
Способ амплификации специфичных фрагментов нуклеиновых кислот с помощью рекуррентной цепной реакции
|
|
EP2171097A2
(de)
*
|
2007-06-29 |
2010-04-07 |
Population Genetics Technologies LTD. |
Verfahren und zusammensetzungen zur isolierung der varianten von nukleinsäuresequenzen
|
|
CN103320506B
(zh)
|
2007-07-03 |
2015-10-28 |
吉纳珀莱有限公司 |
用于改进的核酸扩增反应的嵌合引物
|
|
US8143006B2
(en)
*
|
2007-08-03 |
2012-03-27 |
Igor Kutyavin |
Accelerated cascade amplification (ACA) of nucleic acids comprising strand and sequence specific DNA nicking
|
|
US20090099040A1
(en)
*
|
2007-10-15 |
2009-04-16 |
Sigma Aldrich Company |
Degenerate oligonucleotides and their uses
|
|
US8415099B2
(en)
|
2007-11-05 |
2013-04-09 |
Complete Genomics, Inc. |
Efficient base determination in sequencing reactions
|
|
US20090263872A1
(en)
*
|
2008-01-23 |
2009-10-22 |
Complete Genomics Inc. |
Methods and compositions for preventing bias in amplification and sequencing reactions
|
|
US7897344B2
(en)
*
|
2007-11-06 |
2011-03-01 |
Complete Genomics, Inc. |
Methods and oligonucleotide designs for insertion of multiple adaptors into library constructs
|
|
US8518640B2
(en)
*
|
2007-10-29 |
2013-08-27 |
Complete Genomics, Inc. |
Nucleic acid sequencing and process
|
|
WO2009061840A1
(en)
*
|
2007-11-05 |
2009-05-14 |
Complete Genomics, Inc. |
Methods and oligonucleotide designs for insertion of multiple adaptors employing selective methylation
|
|
WO2009073629A2
(en)
|
2007-11-29 |
2009-06-11 |
Complete Genomics, Inc. |
Efficient shotgun sequencing methods
|
|
US8592150B2
(en)
|
2007-12-05 |
2013-11-26 |
Complete Genomics, Inc. |
Methods and compositions for long fragment read sequencing
|
|
US20090186778A1
(en)
*
|
2008-01-18 |
2009-07-23 |
Ramunas Stepanauskas |
Method for analysis of multiple regions of DNA in single cells of uncultured microorganisms
|
|
WO2009097368A2
(en)
|
2008-01-28 |
2009-08-06 |
Complete Genomics, Inc. |
Methods and compositions for efficient base calling in sequencing reactions
|
|
US20090203531A1
(en)
|
2008-02-12 |
2009-08-13 |
Nurith Kurn |
Method for Archiving and Clonal Expansion
|
|
GB2470672B
(en)
|
2008-03-21 |
2012-09-12 |
Nugen Technologies Inc |
Methods of RNA amplification in the presence of DNA
|
|
MX2010010600A
(es)
|
2008-03-28 |
2011-03-30 |
Pacific Biosciences California Inc |
Composiciones y metodos para secuenciacion de acidos nucleicos.
|
|
WO2009132028A1
(en)
*
|
2008-04-21 |
2009-10-29 |
Complete Genomics, Inc. |
Array structures for nucleic acid detection
|
|
WO2009149013A2
(en)
|
2008-06-05 |
2009-12-10 |
Ventana Medical Systems, Inc. |
Compositions comprising nanomaterials and method for using such compositions for histochemical processes
|
|
KR20100019220A
(ko)
|
2008-08-08 |
2010-02-18 |
삼성전자주식회사 |
열순환을 포함하는 다중 치환 증폭에 의하여 표적 핵산 서열을 증폭하는 방법
|
|
WO2010038042A1
(en)
|
2008-10-02 |
2010-04-08 |
Illumina Cambridge Ltd. |
Nucleic acid sample enrichment for sequencing applications
|
|
JP5794572B2
(ja)
|
2008-10-24 |
2015-10-14 |
エピセンター テクノロジーズ コーポレイションEpicentre Technologies Corporation |
核酸を修飾するためのトランスポゾン末端組成物及び方法
|
|
US9080211B2
(en)
*
|
2008-10-24 |
2015-07-14 |
Epicentre Technologies Corporation |
Transposon end compositions and methods for modifying nucleic acids
|
|
US9593366B2
(en)
|
2008-10-30 |
2017-03-14 |
Qiagen Gaithersburg, Inc. |
Individually synthesized primers to be used in whole genome amplification
|
|
WO2010065629A2
(en)
*
|
2008-12-02 |
2010-06-10 |
Kapabiosystems |
Nucleic acid amplification
|
|
GB0901593D0
(en)
|
2009-01-30 |
2009-03-11 |
Touchlight Genetics Ltd |
Production of closed linear DNA
|
|
EP2401388A4
(de)
*
|
2009-02-23 |
2012-12-05 |
Univ Georgetown |
Sequenzspezifischer nachweis von nukleotidsequenzen
|
|
US9524369B2
(en)
|
2009-06-15 |
2016-12-20 |
Complete Genomics, Inc. |
Processing and analysis of complex nucleic acid sequence data
|
|
WO2011022420A1
(en)
|
2009-08-17 |
2011-02-24 |
Yale University |
Methylation biomarkers and methods of use
|
|
US8182994B2
(en)
|
2009-09-15 |
2012-05-22 |
Illumina Cambridge Limited |
Centroid markers for image analysis of high denisty clusters in complex polynucleotide sequencing
|
|
US20120185176A1
(en)
|
2009-09-30 |
2012-07-19 |
Natera, Inc. |
Methods for Non-Invasive Prenatal Ploidy Calling
|
|
ES2628739T3
(es)
*
|
2009-10-15 |
2017-08-03 |
Ibis Biosciences, Inc. |
Amplificación por desplazamiento múltiple
|
|
US20110312503A1
(en)
|
2010-01-23 |
2011-12-22 |
Artemis Health, Inc. |
Methods of fetal abnormality detection
|
|
USPP22463P3
(en)
*
|
2010-02-16 |
2012-01-17 |
Menachem Bornstein |
Gypsophila plant named ‘Pearl Blossom’
|
|
US8774488B2
(en)
|
2010-03-11 |
2014-07-08 |
Cellscape Corporation |
Method and device for identification of nucleated red blood cells from a maternal blood sample
|
|
US10316362B2
(en)
|
2010-05-18 |
2019-06-11 |
Natera, Inc. |
Methods for simultaneous amplification of target loci
|
|
US9677118B2
(en)
|
2014-04-21 |
2017-06-13 |
Natera, Inc. |
Methods for simultaneous amplification of target loci
|
|
US20190010543A1
(en)
|
2010-05-18 |
2019-01-10 |
Natera, Inc. |
Methods for simultaneous amplification of target loci
|
|
US11326208B2
(en)
|
2010-05-18 |
2022-05-10 |
Natera, Inc. |
Methods for nested PCR amplification of cell-free DNA
|
|
US11332785B2
(en)
|
2010-05-18 |
2022-05-17 |
Natera, Inc. |
Methods for non-invasive prenatal ploidy calling
|
|
US11939634B2
(en)
|
2010-05-18 |
2024-03-26 |
Natera, Inc. |
Methods for simultaneous amplification of target loci
|
|
US11332793B2
(en)
|
2010-05-18 |
2022-05-17 |
Natera, Inc. |
Methods for simultaneous amplification of target loci
|
|
US11408031B2
(en)
|
2010-05-18 |
2022-08-09 |
Natera, Inc. |
Methods for non-invasive prenatal paternity testing
|
|
US12221653B2
(en)
|
2010-05-18 |
2025-02-11 |
Natera, Inc. |
Methods for simultaneous amplification of target loci
|
|
US11322224B2
(en)
|
2010-05-18 |
2022-05-03 |
Natera, Inc. |
Methods for non-invasive prenatal ploidy calling
|
|
EP2572003A4
(de)
|
2010-05-18 |
2016-01-13 |
Natera Inc |
Verfahren zur nichtinvasiven pränatalen ploidiezuordnung
|
|
US11339429B2
(en)
|
2010-05-18 |
2022-05-24 |
Natera, Inc. |
Methods for non-invasive prenatal ploidy calling
|
|
US12152275B2
(en)
|
2010-05-18 |
2024-11-26 |
Natera, Inc. |
Methods for non-invasive prenatal ploidy calling
|
|
WO2012088456A2
(en)
|
2010-12-22 |
2012-06-28 |
Natera, Inc. |
Methods for non-invasive prenatal paternity testing
|
|
WO2012092433A1
(en)
*
|
2010-12-29 |
2012-07-05 |
Ibis Biosciences, Inc. |
Rapid whole genome amplification
|
|
AU2011358564B9
(en)
|
2011-02-09 |
2017-07-13 |
Natera, Inc |
Methods for non-invasive prenatal ploidy calling
|
|
WO2012124681A1
(ja)
*
|
2011-03-14 |
2012-09-20 |
国立大学法人北海道大学 |
核酸増幅方法およびその利用
|
|
US9260753B2
(en)
|
2011-03-24 |
2016-02-16 |
President And Fellows Of Harvard College |
Single cell nucleic acid detection and analysis
|
|
US9347059B2
(en)
|
2011-04-25 |
2016-05-24 |
Bio-Rad Laboratories, Inc. |
Methods and compositions for nucleic acid analysis
|
|
EP2718465B1
(de)
|
2011-06-09 |
2022-04-13 |
Illumina, Inc. |
Verfahren zur vorbereitung eines analyt-arrays
|
|
WO2013024173A1
(en)
|
2011-08-17 |
2013-02-21 |
Technische Universität München |
Computer implemented method for identifying regulatory regions or regulatory variations
|
|
CA2856163C
(en)
|
2011-10-28 |
2019-05-07 |
Illumina, Inc. |
Microarray fabrication system and method
|
|
EP2794927B1
(de)
*
|
2011-12-22 |
2017-04-12 |
Ibis Biosciences, Inc. |
Amplifikationsprimer und verfahren
|
|
US20140100126A1
(en)
|
2012-08-17 |
2014-04-10 |
Natera, Inc. |
Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data
|
|
KR101922124B1
(ko)
|
2012-08-27 |
2018-11-26 |
삼성전자주식회사 |
시료 중 rna로부터 dna를 증폭하는 방법
|
|
WO2014140165A1
(en)
|
2013-03-14 |
2014-09-18 |
Dsm Ip Assets B.V. |
Cell wall deconstruction enzymes of paecilomyces byssochlamydoides and uses thereof
|
|
WO2014140167A1
(en)
|
2013-03-14 |
2014-09-18 |
Dsm Ip Assets B.V. |
Cell wall deconstruction enzymes of malbranchea cinnamomea and uses thereof
|
|
ES2751402T3
(es)
|
2013-03-27 |
2020-03-31 |
Bluegnome Ltd |
Evaluación del riesgo de aneuploidía
|
|
EP2840148B1
(de)
*
|
2013-08-23 |
2019-04-03 |
F. Hoffmann-La Roche AG |
Verfahren für nukleinsäureamplifikation
|
|
EP3039133A1
(de)
|
2013-08-30 |
2016-07-06 |
University of Connecticut |
Modifizierte epstein-barr-virus-dna-polymerase und verfahren zur isothermischen dna-amplifikation
|
|
US10577655B2
(en)
|
2013-09-27 |
2020-03-03 |
Natera, Inc. |
Cell free DNA diagnostic testing standards
|
|
EP3957749A1
(de)
|
2014-04-21 |
2022-02-23 |
Natera, Inc. |
Nachweis von tumorspezifischen mutationen in biopsien mittels sequenzierung des gesamten exoms und in zellfreien proben
|
|
CN106661620B
(zh)
*
|
2014-05-06 |
2021-11-23 |
贝勒医学院 |
单细胞全基因组线性扩增法
|
|
US10570447B2
(en)
|
2014-05-16 |
2020-02-25 |
Illumina, Inc. |
Nucleic acid synthesis techniques
|
|
US20180173845A1
(en)
|
2014-06-05 |
2018-06-21 |
Natera, Inc. |
Systems and Methods for Detection of Aneuploidy
|
|
US10017759B2
(en)
|
2014-06-26 |
2018-07-10 |
Illumina, Inc. |
Library preparation of tagged nucleic acid
|
|
US20170247756A1
(en)
|
2014-10-03 |
2017-08-31 |
Life Technologies Corporation |
Genetic sequence verification compositions, methods and kits
|
|
WO2016077350A1
(en)
|
2014-11-11 |
2016-05-19 |
Illumina, Inc. |
Polynucleotide amplification using crispr-cas systems
|
|
SG10202012249YA
(en)
|
2014-12-08 |
2021-01-28 |
Berg Llc |
Use of markers including filamin a in the diagnosis and treatment of prostate cancer
|
|
US10208339B2
(en)
*
|
2015-02-19 |
2019-02-19 |
Takara Bio Usa, Inc. |
Systems and methods for whole genome amplification
|
|
WO2016183106A1
(en)
|
2015-05-11 |
2016-11-17 |
Natera, Inc. |
Methods and compositions for determining ploidy
|
|
WO2017181202A2
(en)
|
2016-04-15 |
2017-10-19 |
Natera, Inc. |
Methods for lung cancer detection
|
|
WO2017197027A1
(en)
|
2016-05-11 |
2017-11-16 |
Illumina, Inc. |
Polynucleotide enrichment and amplification using argonaute systems
|
|
US10894990B2
(en)
|
2016-05-17 |
2021-01-19 |
Shoreline Biome, Llc |
High throughput method for identification and sequencing of unknown microbial and eukaryotic genomes from complex mixtures
|
|
WO2017205957A1
(en)
|
2016-06-01 |
2017-12-07 |
9087-4405 Quebec Inc. |
Remote access system and method for plant pathogen management
|
|
US11485996B2
(en)
|
2016-10-04 |
2022-11-01 |
Natera, Inc. |
Methods for characterizing copy number variation using proximity-litigation sequencing
|
|
GB201618485D0
(en)
|
2016-11-02 |
2016-12-14 |
Ucl Business Plc |
Method of detecting tumour recurrence
|
|
US10011870B2
(en)
|
2016-12-07 |
2018-07-03 |
Natera, Inc. |
Compositions and methods for identifying nucleic acid molecules
|
|
EP3565907B1
(de)
|
2017-01-06 |
2022-05-04 |
Editas Medicine, Inc. |
Verfahren zur beurteilung der nukleasespaltung
|
|
US10914729B2
(en)
|
2017-05-22 |
2021-02-09 |
The Trustees Of Princeton University |
Methods for detecting protein binding sequences and tagging nucleic acids
|
|
JP2021506342A
(ja)
|
2017-12-14 |
2021-02-22 |
ティーエーアイ ダイアグノスティックス インコーポレイテッドTai Diagnostics,Inc. |
移植のための移植片適合性の評価
|
|
CA3090426A1
(en)
|
2018-04-14 |
2019-10-17 |
Natera, Inc. |
Methods for cancer detection and monitoring by means of personalized detection of circulating tumor dna
|
|
US12234509B2
(en)
|
2018-07-03 |
2025-02-25 |
Natera, Inc. |
Methods for detection of donor-derived cell-free DNA
|
|
WO2020223576A1
(en)
|
2019-04-30 |
2020-11-05 |
Chondrial Therapeutics, Inc. |
Frataxin-sensitive markers for determining effectiveness of frataxin replacement therapy
|
|
EP3980559A1
(de)
|
2019-06-06 |
2022-04-13 |
Natera, Inc. |
Verfahren zur detektion von immunzellen-dna und zur überwachung des immunsystems
|
|
AU2021230282A1
(en)
|
2020-03-03 |
2022-09-22 |
Pacific Biosciences Of California, Inc. |
Methods and compositions for sequencing double stranded nucleic acids
|
|
EP4121561A4
(de)
|
2020-08-06 |
2024-04-17 |
Singular Genomics Systems, Inc. |
Verfahren für in-situ-transkriptomik und proteomik
|
|
WO2022032195A2
(en)
|
2020-08-06 |
2022-02-10 |
Singular Genomics Systems, Inc. |
Spatial sequencing
|
|
WO2022047359A1
(en)
|
2020-08-31 |
2022-03-03 |
Berg Llc |
Protein biomarkers for pancreatic cancer
|
|
US11280028B1
(en)
|
2021-02-24 |
2022-03-22 |
Agency For Science, Technology And Research (A*Star) |
Unbiased and simultaneous amplification method for preparing a double-stranded DNA library from a sample of more than one type of nucleic acid
|
|
BR112023018157A2
(pt)
|
2021-03-09 |
2023-10-31 |
Illumina Inc |
Análise de expressão de variantes codificantes de proteína em células
|
|
CA3209074A1
(en)
|
2021-03-09 |
2022-09-15 |
Andrew Kennedy |
Genomic library preparation and targeted epigenetic assays using cas-grna ribonucleoproteins
|
|
WO2022216841A1
(en)
|
2021-04-06 |
2022-10-13 |
Berg Llc |
Protein markers for estrogen receptor (er)-positive luminal a(la)-like and luminal b1 (lb1)-like breast cancer
|
|
EP4320441A1
(de)
|
2021-04-06 |
2024-02-14 |
BPGbio, Inc. |
Proteinmarker für östrogenrezeptor (er)-positiv- und östrogenrezeptor (er)-negativ-ähnlichen brustkrebs
|
|
EP4320443A1
(de)
|
2021-04-06 |
2024-02-14 |
BPGbio, Inc. |
Proteinmarker zur prognose der brustkrebsprogression
|
|
WO2022235764A1
(en)
|
2021-05-05 |
2022-11-10 |
Singular Genomics Systems, Inc. |
Multiomic analysis device and methods of use thereof
|
|
AU2022328378A1
(en)
|
2021-08-11 |
2024-01-18 |
Illumina, Inc. |
Detection of analytes using targeted epigenetic assays, proximity-induced tagmentation, strand invasion, restriction, or ligation
|
|
EP4505182A1
(de)
|
2022-04-06 |
2025-02-12 |
Larimar Therapeutics, Inc. |
Frataxinempfindliche marker zur überwachung einer frataxinersatztherapie
|
|
WO2023240201A1
(en)
|
2022-06-08 |
2023-12-14 |
Larimar Therapeutics, Inc. |
Frataxin-sensitive markers for monitoring progression and treatment of leigh syndrome
|
|
WO2024202267A1
(en)
*
|
2023-03-30 |
2024-10-03 |
Sony Group Corporation |
Analyzing method by circular nucleic acid formation
|
|
CN121443751A
(zh)
*
|
2023-03-30 |
2026-01-30 |
索尼集团公司 |
分析方法、环状核酸制造方法以及核酸
|
|
EP4720332A1
(de)
|
2023-06-01 |
2026-04-08 |
Singular Genomics Systems, Inc. |
Verfahren und sonden zum nachweis von polynukleotidsequenzen in zellen und geweben
|
|
WO2025010160A1
(en)
|
2023-07-06 |
2025-01-09 |
Pacific Biosciences Of California, Inc. |
Methods and compositions for stabilizing concatemers
|
|
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