ATE383197T1 - Verfahren und vorrichtung zur erzeugung von bewegung in einem dünnen flüssigkeitsfilm - Google Patents

Verfahren und vorrichtung zur erzeugung von bewegung in einem dünnen flüssigkeitsfilm

Info

Publication number
ATE383197T1
ATE383197T1 AT04705396T AT04705396T ATE383197T1 AT E383197 T1 ATE383197 T1 AT E383197T1 AT 04705396 T AT04705396 T AT 04705396T AT 04705396 T AT04705396 T AT 04705396T AT E383197 T1 ATE383197 T1 AT E383197T1
Authority
AT
Austria
Prior art keywords
liquid film
thin liquid
generating movement
substrate
generating
Prior art date
Application number
AT04705396T
Other languages
English (en)
Inventor
Andreas Rathgeber
Matthias Wassermeier
Original Assignee
Advalytix Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10325313A external-priority patent/DE10325313B3/de
Application filed by Advalytix Ag filed Critical Advalytix Ag
Application granted granted Critical
Publication of ATE383197T1 publication Critical patent/ATE383197T1/de

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/80Mixing by means of high-frequency vibrations above one kHz, e.g. ultrasonic vibrations
    • B01F31/86Mixing by means of high-frequency vibrations above one kHz, e.g. ultrasonic vibrations with vibration of the receptacle or part of it
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30Micromixers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Rigid containers without fluid transport within
    • B01L3/5085Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/23Mixing of laboratory samples e.g. in preparation of analysing or testing properties of materials
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/44Mixing of ingredients for microbiology, enzymology, in vitro culture or genetic manipulation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2215/00Auxiliary or complementary information in relation with mixing
    • B01F2215/04Technical information in relation with mixing
    • B01F2215/0413Numerical information
    • B01F2215/0418Geometrical information
    • B01F2215/0427Numerical distance values, e.g. separation, position
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2215/00Auxiliary or complementary information in relation with mixing
    • B01F2215/04Technical information in relation with mixing
    • B01F2215/0413Numerical information
    • B01F2215/0418Geometrical information
    • B01F2215/0431Numerical size values, e.g. diameter of a hole or conduit, area, volume, length, width, or ratios thereof
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2215/00Auxiliary or complementary information in relation with mixing
    • B01F2215/04Technical information in relation with mixing
    • B01F2215/0413Numerical information
    • B01F2215/0436Operational information
    • B01F2215/045Numerical flow-rate values
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2215/00Auxiliary or complementary information in relation with mixing
    • B01F2215/04Technical information in relation with mixing
    • B01F2215/0413Numerical information
    • B01F2215/0436Operational information
    • B01F2215/0454Numerical frequency values
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2215/00Auxiliary or complementary information in relation with mixing
    • B01F2215/04Technical information in relation with mixing
    • B01F2215/0413Numerical information
    • B01F2215/0436Operational information
    • B01F2215/0468Numerical pressure values
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2215/00Auxiliary or complementary information in relation with mixing
    • B01F2215/04Technical information in relation with mixing
    • B01F2215/0413Numerical information
    • B01F2215/0436Operational information
    • B01F2215/0477Numerical time values
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0829Multi-well plates; Microtitration plates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0433Moving fluids with specific forces or mechanical means specific forces vibrational forces
    • B01L2400/0439Moving fluids with specific forces or mechanical means specific forces vibrational forces ultrasonic vibrations, vibrating piezo elements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Dispersion Chemistry (AREA)
  • Transducers For Ultrasonic Waves (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Micromachines (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)
  • Coating Apparatus (AREA)
AT04705396T 2003-02-27 2004-01-27 Verfahren und vorrichtung zur erzeugung von bewegung in einem dünnen flüssigkeitsfilm ATE383197T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10308622 2003-02-27
DE10309183 2003-03-03
DE10325313A DE10325313B3 (de) 2003-02-27 2003-06-04 Verfahren und Vorrichtung zur Erzeugung von Bewegung in einem dünnen Flüssigkeitsfilm

Publications (1)

Publication Number Publication Date
ATE383197T1 true ATE383197T1 (de) 2008-01-15

Family

ID=32930934

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04705396T ATE383197T1 (de) 2003-02-27 2004-01-27 Verfahren und vorrichtung zur erzeugung von bewegung in einem dünnen flüssigkeitsfilm

Country Status (4)

Country Link
US (1) US20070264161A1 (de)
EP (1) EP1596972B1 (de)
AT (1) ATE383197T1 (de)
WO (1) WO2004076047A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004076046A1 (de) * 2003-02-27 2004-09-10 Advalytix Ag Verfahren und vorrichtung zur durchmischung kleiner flüssigkeitsmengen in mikrokavitäten
DE102004051394B4 (de) * 2004-10-21 2006-08-17 Advalytix Ag Verfahren zur Bewegung von kleinen Flüssigkeitsmengen in Mikrokanälen und Mikrokanalsystem
EP1947462A1 (de) * 2005-10-14 2008-07-23 Olympus Corporation Rührer, gefäss und analysegerät
JP2007178408A (ja) * 2005-12-28 2007-07-12 Olympus Corp 反応容器及び分析装置
WO2007088673A1 (ja) * 2006-01-31 2007-08-09 Olympus Corporation 位置検出装置、位置検出方法及び分析装置
GB0914762D0 (en) 2009-08-24 2009-09-30 Univ Glasgow Fluidics apparatus and fluidics substrate
FR2955508B1 (fr) 2010-01-25 2012-03-30 Corning Inc Microreacteurs avec dispositif microfluidique plan et systeme d'application d'ultrasons ; mise en oeuvre de reactions chimiques en leur sein
EP2638381B1 (de) 2010-11-10 2018-09-05 Roche Diagnostics Hematology, Inc. Automatisierte vorrichtung zur vorbereitung von biologischen proben zur untersuchung
GB201103211D0 (en) * 2011-02-24 2011-04-13 Univ Glasgow Fluidics apparatus, use of fluidics apparatus and process for the manufacture of fluidics apparatus
JP6444371B2 (ja) 2013-04-05 2018-12-26 ロッシュ ダイアグノスティクス ヘマトロジー インコーポレイテッド 試験のために生物学的試料を調製する自動化されたシステムおよび方法
GB201420061D0 (en) 2014-11-11 2014-12-24 Univ Glasgow Nebulisation of liquids

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2420864A (en) * 1943-04-17 1947-05-20 Chilowsky Constantin Piezoelectric plastic material and method of making same
NL6511135A (de) * 1965-08-26 1967-02-27
US3433461A (en) * 1967-05-22 1969-03-18 Edison Instr Inc High-frequency ultrasonic generators
US3575383A (en) * 1969-01-13 1971-04-20 John A Coleman Ultrasonic cleaning system, apparatus and method therefor
US3665225A (en) * 1970-08-28 1972-05-23 Iit Res Inst Hybrid surface-wave transducer
US3745812A (en) * 1971-07-07 1973-07-17 Zenith Radio Corp Acoustic imaging apparatus
US3727718A (en) * 1971-11-24 1973-04-17 Us Navy Surface wave ambiguity analyzer
DE2742492C3 (de) * 1977-03-24 1984-07-19 Kohji Yokosuka Kanagawa Toda Ultraschallwandler
JPS5822915B2 (ja) * 1978-08-21 1983-05-12 ティーディーケイ株式会社 超音波トランスデュ−サ
US4691982A (en) * 1984-03-10 1987-09-08 Canon Kabushiki Kaisha Optical coupler
WO1986000141A1 (en) * 1984-06-13 1986-01-03 Unilever Plc Devices for use in chemical test procedures
JPH0660896B2 (ja) * 1984-11-02 1994-08-10 株式会社日立製作所 超音波探触子
US4697195A (en) * 1985-09-16 1987-09-29 Xerox Corporation Nozzleless liquid droplet ejectors
US4908542A (en) * 1987-06-24 1990-03-13 Unisys Saw tapered transducers
US4746882A (en) * 1987-06-24 1988-05-24 Unisys Corporation Saw multiplexer using tapered transducers
GB8911462D0 (en) * 1989-05-18 1989-07-05 Ares Serono Res & Dev Ltd Devices for use in chemical test procedures
US5006749A (en) * 1989-10-03 1991-04-09 Regents Of The University Of California Method and apparatus for using ultrasonic energy for moving microminiature elements
AU4585193A (en) * 1992-07-24 1994-02-14 Kohji Toda Ultrasonic touch system
US5639423A (en) * 1992-08-31 1997-06-17 The Regents Of The University Of Calfornia Microfabricated reactor
US5919712A (en) * 1993-05-18 1999-07-06 University Of Utah Research Foundation Apparatus and methods for multi-analyte homogeneous fluoro-immunoassays
US5512492A (en) * 1993-05-18 1996-04-30 University Of Utah Research Foundation Waveguide immunosensor with coating chemistry providing enhanced sensitivity
US5736100A (en) * 1994-09-20 1998-04-07 Hitachi, Ltd. Chemical analyzer non-invasive stirrer
US6168948B1 (en) * 1995-06-29 2001-01-02 Affymetrix, Inc. Miniaturized genetic analysis systems and methods
JP3487699B2 (ja) * 1995-11-08 2004-01-19 株式会社日立製作所 超音波処理方法および装置
WO1997025531A1 (en) * 1996-01-05 1997-07-17 Berkeley Microinstruments, Inc. Micropump with sonic energy generator
US6720710B1 (en) * 1996-01-05 2004-04-13 Berkeley Microinstruments, Inc. Micropump
US6010316A (en) * 1996-01-16 2000-01-04 The Board Of Trustees Of The Leland Stanford Junior University Acoustic micropump
JPH1154471A (ja) * 1997-08-05 1999-02-26 Tokyo Electron Ltd 処理装置及び処理方法
JPH11347392A (ja) * 1998-06-11 1999-12-21 Hitachi Ltd 攪拌装置
US6948843B2 (en) * 1998-10-28 2005-09-27 Covaris, Inc. Method and apparatus for acoustically controlling liquid solutions in microfluidic devices
US6210128B1 (en) * 1999-04-16 2001-04-03 The United States Of America As Represented By The Secretary Of The Navy Fluidic drive for miniature acoustic fluidic pumps and mixers
US6357907B1 (en) * 1999-06-15 2002-03-19 V & P Scientific, Inc. Magnetic levitation stirring devices and machines for mixing in vessels
US6777245B2 (en) * 2000-06-09 2004-08-17 Advalytix Ag Process for manipulation of small quantities of matter
EP1337324A2 (de) * 2000-09-30 2003-08-27 Aviva Biosciences Corporation Vorrichtungen mit mehreren krafterzeugenden elementen und deren verwendung
DE10062246C1 (de) * 2000-12-14 2002-05-29 Advalytix Ag Verfahren und Vorrichtung zur Manipulation kleiner Flüssigkeitsmengen
DE10117772C2 (de) * 2001-04-09 2003-04-03 Advalytix Ag Mischvorrichtung und Mischverfahren für die Durchmischung kleiner Flüssigkeitsmengen
DE10142789C1 (de) * 2001-08-31 2003-05-28 Advalytix Ag Bewegungselement für kleine Flüssigkeitsmengen
US20040105476A1 (en) * 2002-08-19 2004-06-03 Wasserbauer John G. Planar waveguide surface emitting laser and photonic integrated circuit
GB0221391D0 (en) * 2002-09-16 2002-10-23 Secr Defence Apparatus for directing particles in a fluid
EP1635960A2 (de) * 2003-06-06 2006-03-22 P.C.T. Systems, Inc. Verfahren und vorrichtung zur bearbeitung von substraten mit megaschallenergie
JP4365813B2 (ja) * 2004-09-22 2009-11-18 オリンパス株式会社 攪拌装置、容器および攪拌装置を備えた分析装置
US7287431B2 (en) * 2005-04-14 2007-10-30 Honeywell International Inc. Wireless oil filter sensor
JP2007232522A (ja) * 2006-02-28 2007-09-13 Olympus Corp 攪拌装置と分析装置

Also Published As

Publication number Publication date
WO2004076047A1 (de) 2004-09-10
EP1596972B1 (de) 2008-01-09
US20070264161A1 (en) 2007-11-15
EP1596972A1 (de) 2005-11-23

Similar Documents

Publication Publication Date Title
ATE383197T1 (de) Verfahren und vorrichtung zur erzeugung von bewegung in einem dünnen flüssigkeitsfilm
ATE318179T1 (de) Vorrichtung und verfahren zur manipulation kleiner materiemengen
DE602004026725D1 (de) Verfahren zur bereitstellung einer eingegrenzten flüssigkeit für die immersionslithographie
ATE414974T1 (de) Verfahren und vorrichtung zur positionieren kleiner partikel in einer flüssigkeit
DE69938170D1 (de) Mischverfahren
ATE289531T1 (de) Verfahren und vorrichtung zum auftragen von fluiden
DE602006012436D1 (de) Ultraschallgerät zur Erzeugung von Bewegungsinformationsbildern
EP1344575A4 (de) Vorrichtung zur erzeugung/übertragung von ultraschallwellen
ATE378166T1 (de) Vorrichtung und verfahren für die zerstörungsfreie trennung ausgehärteter materialschichten von einer planen bauebene
DE60222093D1 (de) Verfahren, modul, vorrichtung und server zur spracherkennung
ATE348371T1 (de) Verfahren, vorrichtung, programm und datenträger zur bearbeitung von bilddaten
ATE491987T1 (de) Verfahren und vorrichtung zur erzeugung von zusammengesetzen benutzeroberflächen
ATE507007T1 (de) Vorrichtung und verfahren zur beschichtung einer oberfläche
DE602005005740D1 (de) System und Verfahren zur Ermittlung des Betriebszustands von orthopädischen Zusatzmitteln
ATE468590T1 (de) Verfahren und einrichtung zur erzeugung von alfven-wellen
ATE427782T1 (de) Vorrichtung und verfahren zum anlegen einer schwingbewegung
DE60334118D1 (de) Ultraschallgerät, verfahren zur anzeige von informationen über die verzerrung von biologischem gewebe in einem ultraschallbild
DE60331303D1 (de) Verfahren und vorrichtungen, die die adsorption von chiralen molekülen an einer oberfläche oder grenzfläche verwendenden
DE60222391D1 (de) Verfahren und vorrichtung zur plasmabehandlung von oberflächen
DE60216757D1 (de) Vorrichtung zur ultraschallbehandlung von fluiden
DE602004005158D1 (de) Oberflächenschichtsaffinitätschromatographie
ATE303863T1 (de) Verfahren und vorrichtung zur integrierten synthese und analytbestimmung an einem träger
DK1687612T3 (da) Fremgangsmåde og apparatur til bestemmelse af et lille volumen af en væskeprøve
DE60326484D1 (de) Verfahren und vorrichtung zur generierung von audiokomponenten
DE10321436B8 (de) Vorrichtung zur Erzeugung von Kräften

Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee