ATE383440T1 - Funktionalisierte eingekapselte fluoreszierende nanokristalle - Google Patents
Funktionalisierte eingekapselte fluoreszierende nanokristalleInfo
- Publication number
- ATE383440T1 ATE383440T1 AT01909283T AT01909283T ATE383440T1 AT E383440 T1 ATE383440 T1 AT E383440T1 AT 01909283 T AT01909283 T AT 01909283T AT 01909283 T AT01909283 T AT 01909283T AT E383440 T1 ATE383440 T1 AT E383440T1
- Authority
- AT
- Austria
- Prior art keywords
- functionalized
- fluorescent nanocrystals
- encapsulated fluorescent
- encapsulated
- complexes
- Prior art date
Links
- 239000002159 nanocrystal Substances 0.000 title abstract 8
- 238000001514 detection method Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000000758 substrate Substances 0.000 abstract 2
- 230000005284 excitation Effects 0.000 abstract 1
- 239000002502 liposome Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
- G01N33/586—Liposomes, microcapsules or cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/588—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with semiconductor nanocrystal label, e.g. quantum dots
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2989—Microcapsule with solid core [includes liposome]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2991—Coated
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2991—Coated
- Y10T428/2993—Silicic or refractory material containing [e.g., tungsten oxide, glass, cement, etc.]
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nanotechnology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Medicinal Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Materials Engineering (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Luminescent Compositions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18360800P | 2000-02-18 | 2000-02-18 | |
| US18360700P | 2000-02-18 | 2000-02-18 | |
| US09/783,469 US6761877B2 (en) | 2000-02-18 | 2001-02-14 | Functionalized encapsulated fluorescent nanocrystals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE383440T1 true ATE383440T1 (de) | 2008-01-15 |
Family
ID=27391706
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01909283T ATE383440T1 (de) | 2000-02-18 | 2001-02-16 | Funktionalisierte eingekapselte fluoreszierende nanokristalle |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US6761877B2 (de) |
| EP (1) | EP1266032B1 (de) |
| AT (1) | ATE383440T1 (de) |
| AU (1) | AU2001237057A1 (de) |
| DE (1) | DE60132311T2 (de) |
| WO (1) | WO2001061045A1 (de) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6761877B2 (en) * | 2000-02-18 | 2004-07-13 | Biocrystal, Ltd. | Functionalized encapsulated fluorescent nanocrystals |
| US20050059031A1 (en) * | 2000-10-06 | 2005-03-17 | Quantum Dot Corporation | Method for enhancing transport of semiconductor nanocrystals across biological membranes |
| EP2085781B2 (de) * | 2000-10-06 | 2020-03-11 | Life Technologies Corporation | Zellen mit spektralen Signaturen und Verfahren zur Herstellung und Verwendung davon |
| JP2003028797A (ja) * | 2001-07-11 | 2003-01-29 | Hitachi Software Eng Co Ltd | 蛍光読み取り装置 |
| JP4072994B2 (ja) * | 2001-10-11 | 2008-04-09 | 学校法人日本大学 | 磁性粒子 |
| JP3955225B2 (ja) * | 2002-03-27 | 2007-08-08 | 日立ソフトウエアエンジニアリング株式会社 | 半導体ナノ粒子を用いる反応の反応測定方法及び該測定方法を用いる半導体ナノ粒子の品質評価方法 |
| JP3701622B2 (ja) | 2002-03-27 | 2005-10-05 | 日立ソフトウエアエンジニアリング株式会社 | 半導体ナノ粒子蛍光試薬及び蛍光測定方法 |
| JP3847677B2 (ja) | 2002-07-23 | 2006-11-22 | 日立ソフトウエアエンジニアリング株式会社 | 半導体ナノ粒子、その製造方法、及び半導体ナノ粒子蛍光試薬 |
| JP2004077389A (ja) * | 2002-08-21 | 2004-03-11 | Hitachi Software Eng Co Ltd | 半導体ナノ粒子を含む機能性蛍光試薬 |
| US20050032246A1 (en) * | 2002-11-14 | 2005-02-10 | Mcmaster University | Method of immobilizing membrane-associated molecules |
| US8367324B2 (en) * | 2003-11-17 | 2013-02-05 | Canon Kabushiki Kaisha | Method for judging change in probe-bearing substrate, probe-bearing substrate and detecting apparatus |
| JP4528990B2 (ja) * | 2003-12-09 | 2010-08-25 | 学校法人慶應義塾 | 脂質二重膜とナノサイズ蛍光体複合体 |
| GB0400235D0 (en) * | 2004-01-07 | 2004-02-11 | Univ Sunderland | Nanoparticles as agents for imaging finger prints |
| US20060014175A1 (en) * | 2004-05-17 | 2006-01-19 | Imad Naasani | Functionalized fluorescent nanocrystal detection system |
| US7794600B1 (en) * | 2004-08-27 | 2010-09-14 | Nanosys, Inc. | Purification of nanocrystal solutions by chromatography |
| US8486371B2 (en) * | 2004-09-17 | 2013-07-16 | The Regents Of The University Of Michigan | Quantitative two-photon flow cytometry |
| US20060240227A1 (en) * | 2004-09-23 | 2006-10-26 | Zhijun Zhang | Nanocrystal coated surfaces |
| EP1809720B1 (de) * | 2004-10-29 | 2012-05-02 | Life Technologies Corporation | Funktionalisierte fluoreszierende nanokristalle und verfahren zu deren herstellung und verwendung |
| WO2006084248A2 (en) * | 2005-02-04 | 2006-08-10 | Antigenics, Inc. | Compositions comprising a platinum complex, lipid, and surfactant |
| GB2441666B (en) * | 2005-04-25 | 2010-12-29 | Univ Arkansas | Doped semiconductor nanocrystals and methods of making same |
| JP5330828B2 (ja) | 2005-08-09 | 2013-10-30 | ユニヴァーシティ・オヴ・サンダーランド | 疎水性シリカ粒子およびそれらの製造方法 |
| US8101430B2 (en) | 2005-08-15 | 2012-01-24 | Massachusetts Institute Of Technology | Fluorescent sensor based on two fluorescent moieties one of which is a semiconductor nanocrystal and methods of using and making |
| US8465983B1 (en) * | 2005-08-19 | 2013-06-18 | Gabriel P. Lopez | Detection and delivery systems utilizing supported lipid bilayers |
| US20070134685A1 (en) * | 2005-09-06 | 2007-06-14 | Invitrogen Corporation | Control of chemical modification |
| JP4415972B2 (ja) * | 2005-09-22 | 2010-02-17 | ソニー株式会社 | 金属酸化物ナノ粒子の製造方法 |
| WO2007067257A2 (en) | 2005-12-02 | 2007-06-14 | Vanderbilt University | Broad-emission nanocrystals and methods of making and using same |
| ES2798263T3 (es) | 2005-12-08 | 2020-12-10 | Insmed Inc | Composiciones a base de lípidos de antiinfecciosos para tratar infecciones pulmonares |
| WO2008039912A2 (en) * | 2006-09-27 | 2008-04-03 | Evident Technologies | Retro-emission systems comprising microlens arrays and luminescent emitters |
| US9119783B2 (en) | 2007-05-07 | 2015-09-01 | Insmed Incorporated | Method of treating pulmonary disorders with liposomal amikacin formulations |
| FR2918755B1 (fr) * | 2007-07-09 | 2009-10-30 | Commissariat Energie Atomique | Procede de detection et de quantification d'analytes sur support solide avec des molecules fluorescentes encapsulees dans des immunoliposomes. |
| US20090171330A1 (en) * | 2007-12-28 | 2009-07-02 | Spectranetics | Tunable nanoparticle tags to enhance tissue recognition |
| US20090270269A1 (en) * | 2008-04-28 | 2009-10-29 | Ashok Kumar | Nano-scale fluoro-biosensors exhibiting a low false alarm rate for rapid detection of biological contaminants |
| US20100090164A1 (en) * | 2008-06-10 | 2010-04-15 | Xiaogang Peng | Indium arsenide nanocrystals and methods of making the same |
| US20120034156A1 (en) * | 2010-08-03 | 2012-02-09 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Artificial cells |
| US8895158B2 (en) | 2011-08-10 | 2014-11-25 | The Johns Hopkins University | Nanoparticle taggants for explosive precursors |
| WO2013078252A1 (en) * | 2011-11-22 | 2013-05-30 | Qd Vision, Inc. | Quantum dot-containing compositions including an emission stabilizer, products including same, and method |
| EP2841108A4 (de) * | 2012-04-25 | 2015-11-25 | Tufts College | Seidenmikrokügelchen sowie verfahren zur oberflächenschmierung |
| WO2014085526A1 (en) | 2012-11-29 | 2014-06-05 | Insmed Incorporated | Stabilized vancomycin formulations |
| WO2014134338A1 (en) * | 2013-03-01 | 2014-09-04 | Arizona Board Of Regents, A Body Corporate Of The State Of Arizona, Acting For And On Behalf Of Arizona State University | Oligonucleotide functionalized quantum dots |
| US9229611B2 (en) * | 2013-03-05 | 2016-01-05 | Oracle International Corporation | Automatic management of client data consistency |
| CN107072944B (zh) | 2014-04-08 | 2021-11-02 | 阿拉迪姆公司 | 具有抗非结核分枝杆菌活性的脂质体环丙沙星制剂 |
| CN106456551A (zh) | 2014-04-08 | 2017-02-22 | 阿拉迪姆公司 | 冻融后形成药物纳米晶体的脂质体 |
| PL3142643T3 (pl) | 2014-05-15 | 2019-12-31 | Insmed Incorporated | Sposoby leczenia zakażeń płuc prątkami niegruźliczymi |
| WO2017147407A1 (en) * | 2016-02-25 | 2017-08-31 | Board Of Regents, The University Of Texas System | Compositions comprising composite nanocarriers and methods of making and uses thereof |
| EP3773505A4 (de) | 2018-03-30 | 2021-12-22 | Insmed Incorporated | Verfahren zur kontinuierlichen herstellung von liposomalen arzneimittelprodukten |
| AU2019262117C1 (en) | 2018-05-02 | 2024-12-05 | Insmed Incorporated | Methods for the manufacture of liposomal drug formulations |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4614796A (en) * | 1983-03-25 | 1986-09-30 | Nippon Shinyaku Co., Ltd. | Liposome and method of manufacture therefor |
| WO1987007150A1 (en) * | 1986-05-30 | 1987-12-03 | The Johns Hopkins University | Receptor-targeted drug delivery systems |
| CA1340806C (en) * | 1986-07-02 | 1999-11-02 | James Merrill Prober | Method, system and reagents for dna sequencing |
| US5151507A (en) * | 1986-07-02 | 1992-09-29 | E. I. Du Pont De Nemours And Company | Alkynylamino-nucleotides |
| US5227489A (en) * | 1988-08-01 | 1993-07-13 | Ciba Corning Diagnostics Corp. | Stable hydrophilic acridinium esters suitable for liposome encapsulation |
| US5578718A (en) * | 1990-01-11 | 1996-11-26 | Isis Pharmaceuticals, Inc. | Thiol-derivatized nucleosides |
| US5187085A (en) * | 1990-09-28 | 1993-02-16 | Applied Biosystems, Inc. | Nucleic acid sequence analysis with nucleoside-5'-o-(1-thiotriphosphates) |
| YU187991A (sh) * | 1990-12-11 | 1994-09-09 | Hoechst Aktiengesellschaft | 3-(2)-amino-ali tiol-modifikovani, s fluorescentnom bojom vezani nukleozidi, nukleotidi i oligonukleotidi, postupak za njihovo dobijanje i njihova upotreba |
| US5364759B2 (en) * | 1991-01-31 | 1999-07-20 | Baylor College Medicine | Dna typing with short tandem repeat polymorphisms and identification of polymorphic short tandem repeats |
| US5650277A (en) * | 1992-07-02 | 1997-07-22 | Diagenetics Ltd. | Method of determining the presence and quantifying the number of di- and trinucleotide repeats |
| US6048616A (en) | 1993-04-21 | 2000-04-11 | Philips Electronics N.A. Corp. | Encapsulated quantum sized doped semiconductor particles and method of manufacturing same |
| US5637258A (en) * | 1996-03-18 | 1997-06-10 | Nanocrystals Technology L.P. | Method for producing rare earth activited metal oxide nanocrystals |
| EP1818417B1 (de) * | 1996-07-29 | 2014-02-12 | Nanosphere, Inc. | Nanopartikel mit angehängten Oligonukleotiden und ihre Verwendungen |
| DE19724796A1 (de) * | 1997-06-06 | 1998-12-10 | Max Delbrueck Centrum | Mittel zur Antitumortherapie |
| US6207392B1 (en) * | 1997-11-25 | 2001-03-27 | The Regents Of The University Of California | Semiconductor nanocrystal probes for biological applications and process for making and using such probes |
| US5990479A (en) | 1997-11-25 | 1999-11-23 | Regents Of The University Of California | Organo Luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes |
| US6114038A (en) | 1998-11-10 | 2000-09-05 | Biocrystal Ltd. | Functionalized nanocrystals and their use in detection systems |
| WO2000028089A1 (en) | 1998-11-10 | 2000-05-18 | Biocrystal Limited | Functionalized nanocrystals and their use in labeling for strand synthesis or sequence determination |
| US6221602B1 (en) * | 1998-11-10 | 2001-04-24 | Bio-Pixels Ltd. | Functionalized nanocrystals and their use in labeling for strand synthesis or sequence determination |
| US6194213B1 (en) * | 1999-12-10 | 2001-02-27 | Bio-Pixels Ltd. | Lipophilic, functionalized nanocrystals and their use for fluorescence labeling of membranes |
| US6179912B1 (en) * | 1999-12-20 | 2001-01-30 | Biocrystal Ltd. | Continuous flow process for production of semiconductor nanocrystals |
| US6761877B2 (en) * | 2000-02-18 | 2004-07-13 | Biocrystal, Ltd. | Functionalized encapsulated fluorescent nanocrystals |
-
2001
- 2001-02-14 US US09/783,469 patent/US6761877B2/en not_active Expired - Lifetime
- 2001-02-16 AU AU2001237057A patent/AU2001237057A1/en not_active Abandoned
- 2001-02-16 DE DE60132311T patent/DE60132311T2/de not_active Expired - Lifetime
- 2001-02-16 WO PCT/US2001/005108 patent/WO2001061045A1/en not_active Ceased
- 2001-02-16 AT AT01909283T patent/ATE383440T1/de not_active IP Right Cessation
- 2001-02-16 EP EP01909283A patent/EP1266032B1/de not_active Expired - Lifetime
-
2004
- 2004-06-14 US US10/866,929 patent/US7060252B2/en not_active Expired - Lifetime
-
2005
- 2005-12-12 US US11/301,050 patent/US7244413B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001061045A1 (en) | 2001-08-23 |
| DE60132311D1 (de) | 2008-02-21 |
| DE60132311T2 (de) | 2009-01-02 |
| EP1266032B1 (de) | 2008-01-09 |
| US7244413B2 (en) | 2007-07-17 |
| EP1266032A1 (de) | 2002-12-18 |
| US20060099147A1 (en) | 2006-05-11 |
| EP1266032A4 (de) | 2005-01-19 |
| US6761877B2 (en) | 2004-07-13 |
| US20050019486A1 (en) | 2005-01-27 |
| AU2001237057A1 (en) | 2001-08-27 |
| US20020001716A1 (en) | 2002-01-03 |
| US7060252B2 (en) | 2006-06-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE383440T1 (de) | Funktionalisierte eingekapselte fluoreszierende nanokristalle | |
| DE60234382D1 (de) | Nanokristalle | |
| WO2001053822A3 (de) | Verfahren und einrichtung zur bestimmung temperaturabhängiger parameter | |
| ATE317122T1 (de) | Fluoreszierende polarisation | |
| AU3659002A (en) | Methods, circuits and compositions of matter for in vivo detection of biomolecule concentrations using fluorescent tags | |
| DE69735532D1 (de) | Bestimmung von antigenen mittels oligonukleotid-antikörper-konjugaten | |
| WO2000027365A8 (en) | Functionalized nanocrystals and their use in detection systems | |
| JP2005513471A5 (de) | ||
| ATE409238T1 (de) | Nachweis der hybridisierung von nukleinsäuren durch fluoreszenzpolarisation | |
| DE69635801D1 (de) | Prostataspezifisches membranes antigen und seine anwendungen | |
| AU2002230419A1 (en) | Fluorescence and fret based assays for biomolecules on beads | |
| WO2002059253A3 (en) | Fluorescence detection system including a photonic band gap structure | |
| AU7532501A (en) | Method for increasing luminescence assay sensitivity | |
| ATE487935T1 (de) | Fluorometer | |
| DE69604920D1 (de) | Verwendung einer phycobiliprotein-peptidkomplexverbindung als fluoreszenzlabel | |
| WO2001073443A3 (en) | Methods and compositions for the simultaneous detection of multiple analytes | |
| DE60114804D1 (de) | Konstruierte fluoreszenzproteine mit langen wellenlängen | |
| DE60222091D1 (de) | Dendritische chemilumineszierende Substrate | |
| DE69924147D1 (de) | Floureszenzintensitäts-test für eine protein- oder peptidbindung an nukleinsäuren | |
| DE69732034D1 (de) | Assay-verfahren | |
| ATE336572T1 (de) | Neuen reagenzien in chemilumineszenz- nachweisverfahren | |
| NO20052553L (no) | Cobalaminanalyse. | |
| WO2006073563A3 (en) | Fluorescent affinity tag to enhance phosphoprotein detection | |
| DK0871764T3 (da) | Screeningsfremgangsmåde | |
| ATE274702T1 (de) | Verwendung derivatisierter reagenzien in chemilumineszenz- und elektrochemilumineszenz- nachweisverfahren |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1266032 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |