ATE384717T1 - Stereoisomere indolderivate, verfahren zu ihrer herstellung und ihre verwendung - Google Patents

Stereoisomere indolderivate, verfahren zu ihrer herstellung und ihre verwendung

Info

Publication number: ATE384717T1
Authority: AT; Austria
Prior art keywords: group; alkyl group; stereoisomeric; subjecting; chem
Prior art date: 1997-09-05

Application number

AT98938943T

Other languages

English (en)

Inventor

Masao Mori

Masako Nakagawa

Atsushi Nishida

Mihoko Fuwa

Haruo Saito

Takayuki Matsunaga

Satoshi Takahashi

Chika Hasegawa

Original Assignee

Lead Chem Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-09-05

Filing date

1998-08-24

Publication date

2008-02-15

1997-09-05 Priority claimed from JP9241417A external-priority patent/JPH1180154A/ja

1998-02-09 Priority claimed from JP2697998A external-priority patent/JPH11228573A/ja

1998-08-24 Application filed by Lead Chem Co Ltd filed Critical Lead Chem Co Ltd

2008-02-15 Application granted granted Critical

2008-02-15 Publication of ATE384717T1 publication Critical patent/ATE384717T1/de

Links

238000000034 method Methods 0.000 title abstract 2
SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical class C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 title 1
229940054051 antipsychotic indole derivative Drugs 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 4
150000001408 amides Chemical group 0.000 abstract 3
125000003710 aryl alkyl group Chemical group 0.000 abstract 2
125000003118 aryl group Chemical group 0.000 abstract 2
229910052799 carbon Inorganic materials 0.000 abstract 2
125000004432 carbon atom Chemical group C* 0.000 abstract 2
150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
125000000753 cycloalkyl group Chemical group 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 abstract 1
QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 abstract 1
QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
150000001370 alpha-amino acid derivatives Chemical class 0.000 abstract 1
235000008206 alpha-amino acids Nutrition 0.000 abstract 1
150000001412 amines Chemical class 0.000 abstract 1
125000003277 amino group Chemical group 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
-1 guanidyl group Chemical group 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
125000002883 imidazolyl group Chemical group 0.000 abstract 1
150000002475 indoles Chemical class 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
230000003859 lipid peroxidation Effects 0.000 abstract 1
229940126707 lipid peroxidation inhibitor Drugs 0.000 abstract 1
239000002184 metal Substances 0.000 abstract 1
125000002816 methylsulfanyl group Chemical group [H]C([H])([H])S[*] 0.000 abstract 1
125000002971 oxazolyl group Chemical group 0.000 abstract 1
238000007243 oxidative cyclization reaction Methods 0.000 abstract 1
230000001766 physiological effect Effects 0.000 abstract 1
125000003396 thiol group Chemical group [H]S* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Indole Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT98938943T 1997-09-05 1998-08-24 Stereoisomere indolderivate, verfahren zu ihrer herstellung und ihre verwendung ATE384717T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP9241417A JPH1180154A (ja)	1997-09-05	1997-09-05	立体異性インドール化合物、その製造方法および用途
JP2697998A JPH11228573A (ja)	1998-02-09	1998-02-09	インドール化合物、その製造方法および用途

Publications (1)

Publication Number	Publication Date
ATE384717T1 true ATE384717T1 (de)	2008-02-15

Family

ID=26364843

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT98938943T ATE384717T1 (de)	1997-09-05	1998-08-24	Stereoisomere indolderivate, verfahren zu ihrer herstellung und ihre verwendung

Country Status (10)

Country	Link
US (1)	US6348484B1 (de)
EP (1)	EP1020465B1 (de)
KR (1)	KR100572483B1 (de)
CN (1)	CN1188409C (de)
AT (1)	ATE384717T1 (de)
AU (1)	AU746588B2 (de)
CA (1)	CA2302402C (de)
DE (1)	DE69839056T2 (de)
RU (1)	RU2182908C2 (de)
WO (1)	WO1999012923A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2001012626A1 (en) *	1999-08-13	2001-02-22	Lead Chemical Co., Ltd	Indole compounds, process for the preparation of the same and uses thereof
MY139563A (en)	2002-09-04	2009-10-30	Bristol Myers Squibb Co	Heterocyclic aromatic compounds useful as growth hormone secretagogues
JP4763462B2 (ja) *	2004-02-04	2011-08-31	株式会社エーピーアイコーポレーション	光学活性を有するアルコール及びカルボン酸の製造方法
TW201119651A (en) *	2009-10-26	2011-06-16	Lg Life Sciences Ltd	Pharmaceutical composition comprising indole compound
KR101510936B1 (ko) *	2013-01-29	2015-04-10	제주대학교 산학협력단	비바리 비단망사 추출물을 유효성분으로 포함하는 자가면역질환 또는 염증질환의 예방 및 치료용 조성물
CN104650056B (zh) *	2013-11-21	2017-09-05	华中师范大学	一种5‑(3‑吲哚基)‑噁唑类化合物的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3164982D1 (de) *	1980-04-10	1984-08-30	Sandoz Ag	Isoxazolyl indolamines
JP3354258B2 (ja) *	1993-12-03	2002-12-09	富山化学工業株式会社	新規なインドール類またはその塩

1998
- 1998-08-24 EP EP98938943A patent/EP1020465B1/de not_active Expired - Lifetime
- 1998-08-24 KR KR1020007002384A patent/KR100572483B1/ko not_active Expired - Fee Related
- 1998-08-24 AU AU87493/98A patent/AU746588B2/en not_active Ceased
- 1998-08-24 WO PCT/JP1998/003727 patent/WO1999012923A1/ja not_active Ceased
- 1998-08-24 US US09/486,318 patent/US6348484B1/en not_active Expired - Lifetime
- 1998-08-24 CN CNB988088339A patent/CN1188409C/zh not_active Expired - Fee Related
- 1998-08-24 RU RU2000108477/04A patent/RU2182908C2/ru not_active IP Right Cessation
- 1998-08-24 CA CA002302402A patent/CA2302402C/en not_active Expired - Fee Related
- 1998-08-24 DE DE69839056T patent/DE69839056T2/de not_active Expired - Fee Related
- 1998-08-24 AT AT98938943T patent/ATE384717T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
RU2182908C2 (ru)	2002-05-27
KR100572483B1 (ko)	2006-04-19
DE69839056T2 (de)	2009-01-15
WO1999012923A1 (en)	1999-03-18
US6348484B1 (en)	2002-02-19
EP1020465B1 (de)	2008-01-23
AU746588B2 (en)	2002-05-02
EP1020465A1 (de)	2000-07-19
CN1269798A (zh)	2000-10-11
CN1188409C (zh)	2005-02-09
CA2302402C (en)	2008-12-02
CA2302402A1 (en)	1999-03-18
DE69839056D1 (de)	2008-03-13
HK1030419A1 (en)	2001-05-04
EP1020465A4 (de)	2004-09-15
KR20010023730A (ko)	2001-03-26
AU8749398A (en)	1999-03-29

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Legal Events

Date	Code	Title	Description
2008-07-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties