ATE386053T1 - Verfahren zur isolierung eines intestilanen cholesterin bindenproteins - Google Patents

Verfahren zur isolierung eines intestilanen cholesterin bindenproteins

Info

Publication number: ATE386053T1
Authority: AT; Austria
Prior art keywords: intestilane; isolation; binding protein; cholesterol binding; cholesterol
Prior art date: 2002-08-06

Application number

AT03784089T

Other languages

English (en)

Inventor

Werner Kramer

Wendelin Frick

Original Assignee

Sanofi Aventis Deutschland

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-08-06

Filing date

2003-07-28

Publication date

2008-03-15

2003-07-28 Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland

2008-03-15 Application granted granted Critical

2008-03-15 Publication of ATE386053T1 publication Critical patent/ATE386053T1/de

Links

238000000034 method Methods 0.000 title abstract 2
102000049842 cholesterol binding protein Human genes 0.000 title 1
108010011793 cholesterol binding protein Proteins 0.000 title 1
238000002955 isolation Methods 0.000 title 1
HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 4
235000012000 cholesterol Nutrition 0.000 abstract 2
239000003112 inhibitor Substances 0.000 abstract 1
230000000968 intestinal effect Effects 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Toxicology (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Obesity (AREA)
Hematology (AREA)
Diabetes (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Analytical Chemistry (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

AT03784089T 2002-08-06 2003-07-28 Verfahren zur isolierung eines intestilanen cholesterin bindenproteins ATE386053T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP02017504		2002-08-06

Publications (1)

Publication Number	Publication Date
ATE386053T1 true ATE386053T1 (de)	2008-03-15

Family

ID=31502689

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03784089T ATE386053T1 (de)	2002-08-06	2003-07-28	Verfahren zur isolierung eines intestilanen cholesterin bindenproteins

Country Status (16)

Country	Link
US (2)	US7435727B2 (de)
EP (1)	EP1529061B1 (de)
JP (1)	JP4575772B2 (de)
KR (1)	KR101095288B1 (de)
CN (1)	CN1330667C (de)
AT (1)	ATE386053T1 (de)
AU (1)	AU2003253341C1 (de)
BR (1)	BR0313217A (de)
CA (1)	CA2493487C (de)
DE (1)	DE60319093T2 (de)
IL (2)	IL166492A (de)
MX (1)	MXPA05001264A (de)
NO (2)	NO333437B1 (de)
RU (1)	RU2345089C2 (de)
WO (1)	WO2004014947A1 (de)
ZA (1)	ZA200500053B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0215579D0 (en)	2002-07-05	2002-08-14	Astrazeneca Ab	Chemical compounds
US7135556B2 (en)	2002-07-19	2006-11-14	Schering Corporation	NPC1L1 (NPC3) and methods of use thereof
CA2550215A1 (en)	2003-12-23	2005-07-07	Astrazeneca Ab	Diphenylazetidinone derivates possessing cholesterol absorption inhibitory activity
EP1723414A4 (de)	2004-01-16	2008-03-26	Merck & Co Inc	Npc1l1 (npc3) und verfahren zur identifizierung seiner liganden
ATE450526T1 (de)	2005-06-20	2009-12-15	Schering Corp	Als antagonisten von histamin h3 geeignete piperidinderivate
SA06270191B1 (ar)	2005-06-22	2010-03-29	استرازينيكا ايه بي	مشتقات من 2- أزيتيدينون جديدة باعتبارها مثبطات لامتصاص الكوليسترول لعلاج حالات فرط نسبة الدهون في الدم
US7910698B2 (en)	2006-02-24	2011-03-22	Schering Corporation	NPC1L1 orthologues
TW200811098A (en)	2006-04-27	2008-03-01	Astrazeneca Ab	Chemical compounds
CN1869704B (zh) *	2006-06-14	2010-06-30	厦门大学	快速鉴定与病原菌互作的宿主蛋白的方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4710469A (en)	1986-05-02	1987-12-01	Merck & Co., Inc.	Novel phosphotyrosyl protein phosphatase
WO1990005147A1 (en)	1988-11-10	1990-05-17	Genetics Institute, Inc.	Natural killer stimulatory factor
JPH06500991A (ja)	1990-05-16	1994-01-27	ジェネティックス・インスティテュート・インコーポレイテッド	骨および軟骨誘導蛋白質
US5264372A (en) *	1991-03-15	1993-11-23	Amylin Pharmaceuticals, Inc.	Receptor-based screening methods for amylin agonists and antagonists
RU2052960C1 (ru) *	1992-05-22	1996-01-27	Институт терапии СО РАМН	Способ получения холестеринснижающих веществ
US5518911A (en) *	1995-01-06	1996-05-21	Onyx Pharmaceuticals, Inc.	Human PAK65
JP3088681B2 (ja) *	1997-05-22	2000-09-18	宮城県	形質膜局在シアリダーゼ及びそれをコードするｄｎａ
US6383734B1 (en) *	1998-09-30	2002-05-07	Advanced Research And Technology Institute, Inc.	Method to determine inhibition of PAK3 activation of Raf-1
JP2000166545A (ja) *	1998-12-07	2000-06-20	Snow Brand Milk Prod Co Ltd	胆汁酸活性化リパーゼ
WO2000060062A2 (en)	1999-04-01	2000-10-12	Astrazeneca Uk Limited	Human signal transduction serine/threonine protein kinase
AU4343500A (en) *	1999-04-16	2000-11-02	Schering Corporation	Use of azetidinone compounds
DE10042447A1 (de) *	2000-08-29	2002-03-28	Aventis Pharma Gmbh	Protein aus dem Darm von Wirbeltieren, welches Cholesterin absorbiert, sowie Verwendung dieses Proteins zur Identifizierung von Inhibitoren des intestinalen Cholesterintransports

2003
- 2003-07-28 AT AT03784089T patent/ATE386053T1/de not_active IP Right Cessation
- 2003-07-28 DE DE60319093T patent/DE60319093T2/de not_active Expired - Lifetime
- 2003-07-28 RU RU2005106238/13A patent/RU2345089C2/ru not_active IP Right Cessation
- 2003-07-28 AU AU2003253341A patent/AU2003253341C1/en not_active Ceased
- 2003-07-28 KR KR1020057002084A patent/KR101095288B1/ko not_active Expired - Fee Related
- 2003-07-28 EP EP03784089A patent/EP1529061B1/de not_active Expired - Lifetime
- 2003-07-28 WO PCT/EP2003/008290 patent/WO2004014947A1/en not_active Ceased
- 2003-07-28 JP JP2004526798A patent/JP4575772B2/ja not_active Expired - Fee Related
- 2003-07-28 BR BR0313217-0A patent/BR0313217A/pt not_active IP Right Cessation
- 2003-07-28 CA CA2493487A patent/CA2493487C/en not_active Expired - Fee Related
- 2003-07-28 CN CNB038173328A patent/CN1330667C/zh not_active Expired - Fee Related
- 2003-07-28 MX MXPA05001264A patent/MXPA05001264A/es active IP Right Grant
- 2003-08-06 US US10/635,008 patent/US7435727B2/en not_active Expired - Fee Related
2005
- 2005-01-04 ZA ZA200500053A patent/ZA200500053B/en unknown
- 2005-01-25 IL IL166492A patent/IL166492A/en not_active IP Right Cessation
- 2005-03-04 NO NO20051169A patent/NO333437B1/no not_active IP Right Cessation
2007
- 2007-10-16 US US11/872,855 patent/US7786103B2/en not_active Expired - Fee Related
2009
- 2009-06-17 IL IL199409A patent/IL199409A/en not_active IP Right Cessation
2013
- 2013-01-18 NO NO20130115A patent/NO20130115L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
NO20051169L (no)	2005-05-02
AU2003253341C1 (en)	2009-09-24
NO20130115L (no)	2005-05-02
NO333437B1 (no)	2013-06-03
CA2493487A1 (en)	2004-02-19
DE60319093T2 (de)	2009-02-05
DE60319093D1 (de)	2008-03-27
IL166492A0 (en)	2006-01-15
ZA200500053B (en)	2006-07-26
IL199409A (en)	2010-12-30
CN1330667C (zh)	2007-08-08
RU2005106238A (ru)	2005-08-27
US20040126812A1 (en)	2004-07-01
US20080167451A1 (en)	2008-07-10
EP1529061B1 (de)	2008-02-13
JP4575772B2 (ja)	2010-11-04
BR0313217A (pt)	2005-06-14
MXPA05001264A (es)	2005-04-28
AU2003253341A1 (en)	2004-02-25
JP2006512054A (ja)	2006-04-13
AU2003253341B2 (en)	2009-04-23
KR20060015443A (ko)	2006-02-17
EP1529061A1 (de)	2005-05-11
CN1668642A (zh)	2005-09-14
RU2345089C2 (ru)	2009-01-27
US7786103B2 (en)	2010-08-31
HK1082509A1 (en)	2006-06-09
IL166492A (en)	2010-12-30
US7435727B2 (en)	2008-10-14
WO2004014947A1 (en)	2004-02-19
CA2493487C (en)	2013-01-22
KR101095288B1 (ko)	2011-12-16

Legal Events

Date	Code	Title	Description
2008-08-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

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