ATE388099T1 - Inhalator mit mitteln zur verbesserung der chemischen stabilität einer darin enthaltenen medizinischen aerosollösung - Google Patents

Inhalator mit mitteln zur verbesserung der chemischen stabilität einer darin enthaltenen medizinischen aerosollösung

Info

Publication number
ATE388099T1
ATE388099T1 AT02750541T AT02750541T ATE388099T1 AT E388099 T1 ATE388099 T1 AT E388099T1 AT 02750541 T AT02750541 T AT 02750541T AT 02750541 T AT02750541 T AT 02750541T AT E388099 T1 ATE388099 T1 AT E388099T1
Authority
AT
Austria
Prior art keywords
inhaler
aerosol solution
chemical stability
agents
improving
Prior art date
Application number
AT02750541T
Other languages
English (en)
Inventor
David Lewis
David Ganderton
Brian Meakin
Gaetano Brambilla
Alessandra Ferraris
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Application granted granted Critical
Publication of ATE388099T1 publication Critical patent/ATE388099T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/14—Containers for dispensing liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant
    • B65D83/44—Valves specially adapted for the discharge of contents; Regulating devices
    • B65D83/52—Metering valves; Metering devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/14—Containers for dispensing liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant
    • B65D83/38—Details of the container body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Dispersion Chemistry (AREA)
  • Mechanical Engineering (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
AT02750541T 2001-03-12 2002-03-12 Inhalator mit mitteln zur verbesserung der chemischen stabilität einer darin enthaltenen medizinischen aerosollösung ATE388099T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01105410A EP1241113A1 (de) 2001-03-12 2001-03-12 Inhalator mit Mitteln um chemische Stabilität der darin enthaltenen medizinischen Aerosollösung zu verbessern

Publications (1)

Publication Number Publication Date
ATE388099T1 true ATE388099T1 (de) 2008-03-15

Family

ID=8176686

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02750541T ATE388099T1 (de) 2001-03-12 2002-03-12 Inhalator mit mitteln zur verbesserung der chemischen stabilität einer darin enthaltenen medizinischen aerosollösung

Country Status (9)

Country Link
EP (2) EP1241113A1 (de)
JP (1) JP2004526495A (de)
AT (1) ATE388099T1 (de)
AU (1) AU2002308254B2 (de)
BR (1) BR0208363A (de)
CA (1) CA2437746A1 (de)
DE (1) DE60225421T9 (de)
NZ (1) NZ528443A (de)
WO (1) WO2002072448A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2342463T3 (es) 2002-03-01 2010-07-07 Chiesi Farmaceutici S.P.A. Formulacion superfina de formoterol.
EP1915985A1 (de) 2003-03-20 2008-04-30 Boehringer Ingelheim Pharmaceuticals Inc. Formulierung für einen Dosierinhalator mit Hydrofluoralkanen als Treibstoffen
DK1608336T3 (da) 2003-03-20 2008-06-02 Boehringer Ingelheim Pharma Formulering til en doseringsinhalator med hydrofluorakaner som drivmidler
AU2004264941B2 (en) * 2003-08-11 2008-11-27 Glaxo Group Limited Pharmaceutical metered dose inhaler and methods relating thereto
EP1925293A3 (de) * 2003-10-20 2010-01-13 Schering Corporation Pharmazeutische Aerosol-Zusammensetzungen
CN1870976A (zh) * 2003-10-20 2006-11-29 先灵公司 药物组合物
KR101297061B1 (ko) 2004-07-02 2013-08-19 베링거 인겔하임 인터내셔날 게엠베하 추진제로서 ｔｇ ２２７ ｅａ 또는 ｔｇ １３４ ａ를함유하는 에어로졸 현탁액 제형
CN101238047B (zh) * 2005-08-08 2010-06-16 诺瓦提斯公司 用于定量吸入器的隔热筒罐
EP1998833B1 (de) * 2006-03-24 2012-12-26 3M Innovative Properties Company Behälter für medizinische formulierung mit behandelter metalloberfläche
DE102006017320A1 (de) 2006-04-11 2007-10-18 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolsuspensionsformulierungen mit TG 227 ea oder TG 134 a als Treibmittel
BRPI0721256A2 (pt) * 2007-02-09 2013-03-12 Schering Corp aerossàis de fÁrmaco farmacÊuticos estÁveis
US8227027B2 (en) 2007-12-07 2012-07-24 Presspart Gmbh & Co. Kg Method for applying a polymer coating to an internal surface of a container
ES2589795T3 (es) * 2012-09-20 2016-11-16 Presspart Gmbh & Co. Kg Recipiente para inhalador de dosis medida y método para producir un recipiente de este tipo
RS57687B1 (sr) * 2013-12-30 2018-11-30 Chiesi Farm Spa Pod pritiskom stabilan aerosolni rastvor kompozicije glikopironijum bromida i kombinacije formoterola
NZ789880A (en) * 2020-01-28 2026-01-30 Chiesi Farm Spa Pressurised metered dose inhalers comprising a buffered pharmaceutical formulation

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4271875A (en) * 1978-09-21 1981-06-09 Philip Meshberg Dispenser adapted for fast pressure filling
US4800903A (en) * 1985-05-24 1989-01-31 Ray Jon P Nicotine dispenser with polymeric reservoir of nicotine
ATE177941T1 (de) 1992-12-09 1999-04-15 Boehringer Ingelheim Pharma Stabilisierte medizinische aerosollösungen
US5899201A (en) * 1993-05-26 1999-05-04 Minnesota Mining And Manufacturing Company Aerosol actuator
PT735884E (pt) 1993-12-20 2000-09-29 Minnesota Mining & Mfg Formulacoes de aerossol de flunisolida
HU219900B (hu) 1995-04-14 2001-09-28 Glaxo Wellcome Inc. Mért dózist adagoló inhalálóberendezés
JP2002512871A (ja) * 1998-04-30 2002-05-08 スリーエム イノベイティブ プロパティズ カンパニー 製薬エアロゾル用定量弁
DZ2947A1 (fr) 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
US6290930B1 (en) 1998-12-18 2001-09-18 Baker Norton Pharmaceuticals, Inc. Pharmaceutical solution aerosol formulations containing fluoroalkanes and budesonide
FR2793478B1 (fr) * 1999-05-11 2001-07-27 Oreal Dispositif de montage d'une valve sur un reservoir, et distributeur contenant un produit sous pression, equipe d'un tel dispositif
US6315985B1 (en) 1999-06-18 2001-11-13 3M Innovative Properties Company C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability
AU2000250701B2 (en) 2000-05-22 2004-07-01 Chiesi Farmaceutici S.P.A. Stable pharmaceutical solution formulations for pressurised metered dose inhalers

Also Published As

Publication number Publication date
EP1368253B1 (de) 2008-03-05
CA2437746A1 (en) 2002-09-19
WO2002072448A1 (en) 2002-09-19
JP2004526495A (ja) 2004-09-02
AU2002308254B2 (en) 2007-05-17
EP1241113A1 (de) 2002-09-18
AU2002308254C1 (en) 2002-09-24
EP1368253A1 (de) 2003-12-10
BR0208363A (pt) 2004-03-09
DE60225421D1 (de) 2008-04-17
DE60225421T2 (de) 2009-07-16
NZ528443A (en) 2004-08-27
DE60225421T9 (de) 2010-04-15

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