BRPI0408547A - formulação para um inalador com dosador usando hidro-flúor-alcanos como propelentes - Google Patents

formulação para um inalador com dosador usando hidro-flúor-alcanos como propelentes

Info

Publication number
BRPI0408547A
BRPI0408547A BRPI0408547-7A BRPI0408547A BRPI0408547A BR PI0408547 A BRPI0408547 A BR PI0408547A BR PI0408547 A BRPI0408547 A BR PI0408547A BR PI0408547 A BRPI0408547 A BR PI0408547A
Authority
BR
Brazil
Prior art keywords
hydro
formulation
fluor
metered dose
dose inhaler
Prior art date
Application number
BRPI0408547-7A
Other languages
English (en)
Inventor
George Destefano
Linda Jean Kelash-Cannavo
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of BRPI0408547A publication Critical patent/BRPI0408547A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

"FORMULAçãO PARA UM INALADOR COM DOSADOR USANDO HIDRO-FLúOR-ALCANOS COMO PROPELENTES". A presente invenção refere-se a uma formulação em suspensão aperfeiçoada para uso em um inalador com dosador tendo um propelente de hidro-flúor-alcano, sendo o aperfeiçoamento a adição controlada de pequena quantidade de água.
BRPI0408547-7A 2003-03-20 2004-03-19 formulação para um inalador com dosador usando hidro-flúor-alcanos como propelentes BRPI0408547A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45611303P 2003-03-20 2003-03-20
PCT/US2004/008375 WO2004084858A2 (en) 2003-03-20 2004-03-19 Formulation for a metered dose inhaler using hydro-fluoro-alkanes as propellants

Publications (1)

Publication Number Publication Date
BRPI0408547A true BRPI0408547A (pt) 2006-03-07

Family

ID=33098086

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0408547-7A BRPI0408547A (pt) 2003-03-20 2004-03-19 formulação para um inalador com dosador usando hidro-flúor-alcanos como propelentes

Country Status (28)

Country Link
US (1) US7914770B2 (pt)
EP (1) EP1608336B1 (pt)
JP (1) JP4708332B2 (pt)
KR (1) KR101113003B1 (pt)
CN (1) CN1761455A (pt)
AT (1) ATE390125T1 (pt)
AU (1) AU2004224367B2 (pt)
BR (1) BRPI0408547A (pt)
CA (1) CA2519523C (pt)
CO (1) CO5640070A2 (pt)
CY (1) CY1108137T1 (pt)
DE (1) DE602004012718T2 (pt)
DK (1) DK1608336T3 (pt)
EA (1) EA009087B1 (pt)
EC (1) ECSP056029A (pt)
ES (1) ES2304616T3 (pt)
HR (1) HRP20050822B1 (pt)
ME (1) ME00420B (pt)
MX (1) MXPA05009920A (pt)
NO (1) NO336457B1 (pt)
NZ (1) NZ542957A (pt)
PL (1) PL1608336T3 (pt)
PT (1) PT1608336E (pt)
RS (1) RS51663B (pt)
SI (1) SI1608336T1 (pt)
UA (1) UA89751C2 (pt)
WO (1) WO2004084858A2 (pt)
ZA (1) ZA200506463B (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004011381A1 (de) * 2004-03-05 2005-09-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Impaktionsdüse für treibgasbetriebene Dosieraerosole
PL1809243T5 (pl) * 2004-07-02 2022-12-27 Boehringer Ingelheim International Gmbh Preparaty aerozolowe w postaci zawiesin z tg 227 ea jako propelent aerozolowy
US20060140873A1 (en) * 2004-12-27 2006-06-29 Chang Heng W Aerosol pharmaceutical compositions
GB0501956D0 (en) * 2005-01-31 2005-03-09 Arrow Internat Nebulizer formulation
GB0518769D0 (en) * 2005-09-14 2005-10-19 Medpharm Ltd Topical formulations
DE102006053374A1 (de) * 2006-02-09 2007-08-16 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmazeutische Formulierung für Aerosole mit zwei oder mehr Wirkstoffen und mindestens einer oberflächenaktiven Substanz
DE102006014433A1 (de) * 2006-03-27 2007-10-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Dosieraerosole für die Verabreichung von pharmazeutischen Zubereitungen
DE102006017320A1 (de) * 2006-04-11 2007-10-18 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolsuspensionsformulierungen mit TG 227 ea oder TG 134 a als Treibmittel
WO2008047239A2 (en) * 2006-09-21 2008-04-24 Medispray Laboratories Pvt. Ltd. Stable aerosol pharmaceutical formulations
JP5358574B2 (ja) * 2007-08-17 2013-12-04 アルション セラピューティクス， インコーポレイテッド 高濃度の局所麻酔薬調合物
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
US8119694B2 (en) 2008-08-15 2012-02-21 Arcion Therapeutics, Inc. High concentration local anesthetic formulations
EP2414560B1 (de) 2009-03-31 2013-10-23 Boehringer Ingelheim International GmbH Verfahren zur beschichtung einer oberfläche eines bauteils
US9265910B2 (en) 2009-05-18 2016-02-23 Boehringer Ingelheim International Gmbh Adapter, inhalation device, and nebulizer
EP2504051B1 (en) 2009-11-25 2019-09-04 Boehringer Ingelheim International GmbH Nebulizer
CA2781792C (en) 2009-11-25 2019-04-02 Boehringer Ingelheim International Gmbh Nebulizer
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
EP2585151B1 (en) 2010-06-24 2018-04-04 Boehringer Ingelheim International GmbH Nebulizer
US20120204871A1 (en) * 2011-02-10 2012-08-16 Julio Cesar Vega Stable, non-corrosive formulations for pressurized metered dose inhalers
EP2694220B1 (de) 2011-04-01 2020-05-06 Boehringer Ingelheim International GmbH Medizinisches gerät mit behälter
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
CN102798044B (zh) * 2012-08-02 2014-09-10 深圳市华星光电技术有限公司 侧入式背光模组
ES2836977T3 (es) 2013-08-09 2021-06-28 Boehringer Ingelheim Int Nebulizador
JP6643231B2 (ja) 2013-08-09 2020-02-12 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
BR112016023983B1 (pt) 2014-05-07 2022-10-18 Boehringer Ingelheim International Gmbh Contentor para um nebulizador, nebulizador para um fluido e método para conectar um contentor a um dispositivo indicador
SG11201608891RA (en) 2014-05-07 2016-11-29 Boehringer Ingelheim Int Nebulizer, indicator device and container
WO2015169430A1 (en) 2014-05-07 2015-11-12 Boehringer Ingelheim International Gmbh Nebulizer
EP3280393A1 (en) * 2015-04-10 2018-02-14 3M Innovative Properties Company Formulation and aerosol canisters, inhalers, and the like containing the formulation
GB2573297A (en) * 2018-04-30 2019-11-06 Mexichem Fluor Sa De Cv Pharmaceutical composition
WO2021216779A1 (en) * 2020-04-21 2021-10-28 Amphastar Pharmaceuticals, Inc. Anti-viral pharmaceutical formulations administered via devices for lung targeted delivery

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405598A (en) * 1976-01-30 1983-09-20 Fisons, Limited Composition for treating asthma
GB8824804D0 (en) 1988-10-22 1988-11-30 Fisons Plc Device
US5225183A (en) 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
US5919435A (en) 1990-11-09 1999-07-06 Glaxo Group Limited Aerosol formulation containing a particulate medicament
GB9202519D0 (en) * 1992-02-06 1992-03-25 Glaxo Group Ltd Medicaments
WO1994013262A1 (en) * 1992-12-09 1994-06-23 Boehringer Ingelheim Pharmaceuticals, Inc. Stabilized medicinal aerosol solution formulations
DE69701051T2 (de) 1993-04-30 2000-08-31 Minnesota Mining And Mfg. Co., Saint Paul Abdichtung an Aerosolbehältern
CA2166970C (en) 1993-07-15 2000-12-19 Oh-Seung Kwon Seals for use in an aerosol delivery device
EA000889B1 (ru) * 1995-04-14 2000-06-26 Глаксо Веллкам Инк. Дозирующий ингалятор дипропионата беклометазона
GB9513084D0 (en) 1995-06-27 1995-08-30 Bespak Plc Dispensing apparatus
SE9701750D0 (sv) 1997-05-12 1997-05-12 Astra Pharma Prod Inhalation device and method of manufacture thereof
GB2326334A (en) * 1997-06-13 1998-12-23 Chiesi Farma Spa Pharmaceutical aerosol compositions
US20010031244A1 (en) 1997-06-13 2001-10-18 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
US6423298B2 (en) * 1998-06-18 2002-07-23 Boehringer Ingelheim Pharmaceuticals, Inc. Pharmaceutical formulations for aerosols with two or more active substances
AU749697B2 (en) * 1998-08-04 2002-07-04 Jagotec Ag Medicinal aerosol formulations
IT1303788B1 (it) 1998-11-25 2001-02-23 Chiesi Farma Spa Formulazioni di aerosol medicinali.
DZ2947A1 (fr) 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
US7074388B2 (en) * 1998-12-10 2006-07-11 Kos Life Science, Inc. Water stabilized medicinal aerosol formulation
US6261539B1 (en) 1998-12-10 2001-07-17 Akwete Adjei Medicinal aerosol formulation
US20030008369A1 (en) * 1999-03-03 2003-01-09 Board Of Regents, The University Of Texas System Genetic and epigenetic manipulation of ABC transporters and ecto-phosphatases
GB0002798D0 (en) 2000-02-09 2000-03-29 Glaxo Group Ltd Actuator nozzle for metered dose inhaler
EP1241113A1 (en) 2001-03-12 2002-09-18 CHIESI FARMACEUTICI S.p.A. Inhaler with means for improving chemical stability of medicinal aerosol solution contained therein
CA2452140C (en) 2001-06-26 2010-12-14 Norton Healthcare, Ltd. An improved aerosol actuator

Also Published As

Publication number Publication date
WO2004084858A2 (en) 2004-10-07
ECSP056029A (es) 2006-01-27
PT1608336E (pt) 2008-04-21
EA009087B1 (ru) 2007-10-26
JP2006520797A (ja) 2006-09-14
ATE390125T1 (de) 2008-04-15
ME00420B (me) 2011-12-20
KR101113003B1 (ko) 2012-02-24
NO20054839L (no) 2005-10-19
CN1761455A (zh) 2006-04-19
UA89751C2 (ru) 2010-03-10
MXPA05009920A (es) 2005-11-04
CA2519523C (en) 2012-03-13
CA2519523A1 (en) 2004-10-07
DE602004012718D1 (de) 2008-05-08
WO2004084858A3 (en) 2004-11-04
HRP20050822B1 (hr) 2013-09-30
CO5640070A2 (es) 2006-05-31
RS51663B (sr) 2011-10-31
US7914770B2 (en) 2011-03-29
EP1608336B1 (en) 2008-03-26
AU2004224367B2 (en) 2009-10-08
DE602004012718T2 (de) 2009-05-07
PL1608336T3 (pl) 2008-09-30
CY1108137T1 (el) 2014-02-12
KR20050111382A (ko) 2005-11-24
ES2304616T3 (es) 2008-10-16
HRP20050822A2 (en) 2006-10-31
JP4708332B2 (ja) 2011-06-22
NO336457B1 (no) 2015-08-31
NZ542957A (en) 2008-09-26
US20040184994A1 (en) 2004-09-23
EP1608336A2 (en) 2005-12-28
RS20050705A (sr) 2008-04-04
AU2004224367A1 (en) 2004-10-07
EA200501363A1 (ru) 2006-04-28
SI1608336T1 (sl) 2008-08-31
ZA200506463B (en) 2006-04-26
DK1608336T3 (da) 2008-06-02

Similar Documents

Publication Publication Date Title
BRPI0408547A (pt) formulação para um inalador com dosador usando hidro-flúor-alcanos como propelentes
BRPI0607762B8 (pt) análogos de glp-1, composição farmacêutica contendo os mesmos e uso de um composto
BR0111667A (pt) Novos compostos
PA8575401A1 (es) Derivados de heteroarilamida benzocondensada de tienopiridinas utiles como agentes terapeuticos, composiciones farmaceuticas que incluyen a los mismos y metrodos para su uso
UY30314A1 (es) Derivados de benzonitrilo sustituidos con glucopiranosilo, composiciones farmacéuticas que contienen compuestos de este tipo, su uso y procedimiento para su fabricacion
UY27329A1 (es) Champues con alcohol de behenilo
AR024634A1 (es) Composicion farmaceutica estabilizada en forma liofilizada
ECSP077299A (es) Nuevas composiciones farmacéuticas que comprenden ácido 4-(4-(3-(4-cloro-3-trifluorometil-fenil)-ureido)-3-fluoro-fenoxi)-piridin-2-carboxílico para el tratamiento de trastornos hiperproliferativos
AR003427A1 (es) Péptidos relacionados con dolastatina, procedimiento para prepararlos, composiciones farmacéuticas que los contienen y el uso de los mismos para la preparación de dichas composiciones farmacéuticas.
CR6726A (es) Compuestos azapoliciclicos condensados con arilo
FI964285A0 (fi) Taksaanien luokkaan kuuluviin johdannaisiin perustuvat farmaseuttiset valmisteet
CL2004000954A1 (es) Composicion parasiticida en animales que contiene flumetrina y mkg 264 (n-octil biciclohepteno dicarboxamida) en una relacion en peso de al menos 1:20, eventualmente otros principios activos vehiculos y coadyuvantes, y uso de la composicion para prep
BR0107667A (pt) Composto de linezolida em forma de cristal que e farmaceuticamente útil como agente antibacteriano e método de preparação do mesmo
PA8568101A1 (es) Indolil-urea derivados de tienopiridinas utiles como agentes antiangiogenicos, y procedimientos para su uso
PA8532001A1 (es) Bifenilcarboxamidas utiles como agentes reductores de lipidos
UY29234A1 (es) Derivados de adamantano, composiciones farmacéuticas que los contienen, procedimientos de preparación de ambos y aplicaciones.
BRPI0409359A (pt) análogos quiméricos de somatostatina-dopamina
AR045649A1 (es) Una crema para modelar el cabello
BRPI0620431A8 (pt) uso de um poliuretano formador de película, preparação farmacêutica líquida, aplicador e emplastro contendo a referida preparação farmacêutica
ES2129448T3 (es) Uso de 2-(2-nitro-4-trifluorometilbenzoil)-1,3-ciclohexanodiona en el tratamiento de tirosinemia y composiciones farmaceuticas.
AR053691A1 (es) Agentes endoparasiticidas
BRPI0519006A2 (pt) uso de um inibidor de fbpase, kit de uma composiÇço farmacÊutica, uso de uma preparaÇço de biguanida e um inibidor de fbpase, agente terapÊutico para diabetes melito, e, combinaÇço de agentes terapÊuticos
CL2007002788A1 (es) Un compuesto derivado de (cis)-8-fluorodibenzo[b,f]pirido[1,2-d]oxazepin-1-amina, modulador de los receptores de progesterona; composicion farmaceutica; y uso como anticonceptivo, para la terapia de reemplazo hormonal o para el tratamiento de un tras
SE0403117D0 (sv) New compounds 1
DE602004027629D1 (de) d-(17alpha)-13-ETHYL-17HYDROXY-18,19-DINORPREGN-4-ENE-20-YNE-3-ONE IN FORM DES REINEN 3E- UND 3Z-OXIMES SOWIE DAS VERFAHREN ZUR HERSTELLUNG DER MISCHU

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: PARA:INT.CI.A61K 9/00, A61K 9/10, A61K 9/72, A61K 9/00, A61K 9/10, A61K 9/72, A61P 11/00

Ipc: A61K 9/00 (2011.01), A61K 9/10 (2011.01), A61K 9/7

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8 E 13 DA LPI

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.