ATE389397T1 - Adjuvante zusammensetzungen - Google Patents
Adjuvante zusammensetzungenInfo
- Publication number
- ATE389397T1 ATE389397T1 AT05701990T AT05701990T ATE389397T1 AT E389397 T1 ATE389397 T1 AT E389397T1 AT 05701990 T AT05701990 T AT 05701990T AT 05701990 T AT05701990 T AT 05701990T AT E389397 T1 ATE389397 T1 AT E389397T1
- Authority
- AT
- Austria
- Prior art keywords
- adjuvant
- protein
- carbohydrate
- extracts
- cells
- Prior art date
Links
- 239000002671 adjuvant Substances 0.000 title abstract 7
- 239000000203 mixture Substances 0.000 title abstract 4
- 239000000284 extract Substances 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- 230000002238 attenuated effect Effects 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 2
- 239000002245 particle Substances 0.000 abstract 2
- 229920001282 polysaccharide Polymers 0.000 abstract 2
- 239000005017 polysaccharide Substances 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 230000003612 virological effect Effects 0.000 abstract 2
- HVCOBJNICQPDBP-UHFFFAOYSA-N 3-[3-[3,5-dihydroxy-6-methyl-4-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-2-yl]oxydecanoyloxy]decanoic acid;hydrate Chemical compound O.OC1C(OC(CC(=O)OC(CCCCCCC)CC(O)=O)CCCCCCC)OC(C)C(O)C1OC1C(O)C(O)C(O)C(C)O1 HVCOBJNICQPDBP-UHFFFAOYSA-N 0.000 abstract 1
- 229930186217 Glycolipid Natural products 0.000 abstract 1
- 102000003886 Glycoproteins Human genes 0.000 abstract 1
- 108090000288 Glycoproteins Proteins 0.000 abstract 1
- 229930013930 alkaloid Natural products 0.000 abstract 1
- 150000003797 alkaloid derivatives Chemical class 0.000 abstract 1
- 239000013566 allergen Substances 0.000 abstract 1
- 229940037003 alum Drugs 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 150000004676 glycans Chemical class 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 230000003278 mimic effect Effects 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- -1 polysaccharides carbohydrate Chemical class 0.000 abstract 1
- 210000004881 tumor cell Anatomy 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
- 210000000605 viral structure Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/208—IL-12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0401239.9A GB0401239D0 (en) | 2004-01-21 | 2004-01-21 | Adjuvant compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE389397T1 true ATE389397T1 (de) | 2008-04-15 |
Family
ID=31971168
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05701990T ATE389397T1 (de) | 2004-01-21 | 2005-01-21 | Adjuvante zusammensetzungen |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20090047306A1 (de) |
| EP (1) | EP1711174B1 (de) |
| AT (1) | ATE389397T1 (de) |
| AU (1) | AU2005205968C1 (de) |
| CA (1) | CA2553986A1 (de) |
| DE (1) | DE602005005449T2 (de) |
| GB (1) | GB0401239D0 (de) |
| WO (1) | WO2005070415A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1104306B1 (de) * | 1998-08-10 | 2006-01-11 | Antigenics Inc. | Cpg-zusammensetzungen, saponin-adjuvantien und verfahren zu deren verwendung |
| JP4812942B2 (ja) * | 1999-02-26 | 2011-11-09 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル | ＣＧモチーフを含むオリゴヌクレオチドを用いるＮｅｉｓｓｅｒｉａ抗原殺菌活性の増強 |
| GB0401238D0 (en) * | 2004-01-21 | 2004-02-25 | Molecularnature Ltd | Immunomodulatory alkaloids |
| CA2662164A1 (en) | 2006-09-01 | 2008-03-06 | Stirling John Edwards | Method of eliciting or inducing an immune response |
| EP2728006B1 (de) * | 2007-10-10 | 2017-11-22 | Athenix Corporation | CRY1AC-codierende synthetische Gene |
| JP2011500514A (ja) | 2007-10-12 | 2011-01-06 | シーエスエル、リミテッド | 汎発流行性インフルエンザウィルスに対する免疫応答を惹起する方法 |
| JP6873482B2 (ja) * | 2015-10-08 | 2021-05-19 | オンコセラピー・サイエンス株式会社 | Ｆｏｘｍ１由来ペプチドおよびそれを含むワクチン |
| IL286493B (en) | 2015-11-06 | 2022-07-01 | Memorial Sloan Kettering Cancer Center | Triterpene saponin analogues, methods of producing same, compositions comprising same and uses thereof |
| AU2018258070A1 (en) | 2017-04-25 | 2019-10-24 | Adjuvance Technologies, Inc. | Triterpene saponin analogues |
| WO2019079160A1 (en) | 2017-10-16 | 2019-04-25 | Adjuvance Technologies, Inc. | TRITERPENIC SAPONIN ANALOGS |
| WO2022243996A1 (en) * | 2021-05-18 | 2022-11-24 | Attias Eyal | Use of erythropoietin (epo) or erythropoiesis-stimulating agent (esa) to treat osteomyelitis, bone infection, and bone inflammation |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0301554D0 (en) * | 2003-01-23 | 2003-02-26 | Molecularnature Ltd | Immunostimulatory compositions |
-
2004
- 2004-01-21 GB GBGB0401239.9A patent/GB0401239D0/en not_active Ceased
-
2005
- 2005-01-21 WO PCT/GB2005/000228 patent/WO2005070415A1/en not_active Ceased
- 2005-01-21 EP EP05701990A patent/EP1711174B1/de not_active Expired - Lifetime
- 2005-01-21 AT AT05701990T patent/ATE389397T1/de not_active IP Right Cessation
- 2005-01-21 CA CA002553986A patent/CA2553986A1/en not_active Abandoned
- 2005-01-21 US US10/597,296 patent/US20090047306A1/en not_active Abandoned
- 2005-01-21 AU AU2005205968A patent/AU2005205968C1/en not_active Ceased
- 2005-01-21 DE DE602005005449T patent/DE602005005449T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005205968A1 (en) | 2005-08-04 |
| AU2005205968B8 (en) | 2010-08-05 |
| AU2005205968B2 (en) | 2010-07-29 |
| GB0401239D0 (en) | 2004-02-25 |
| AU2005205968C1 (en) | 2010-12-02 |
| EP1711174B1 (de) | 2008-03-19 |
| WO2005070415A1 (en) | 2005-08-04 |
| CA2553986A1 (en) | 2005-08-04 |
| DE602005005449D1 (de) | 2008-04-30 |
| US20090047306A1 (en) | 2009-02-19 |
| DE602005005449T2 (de) | 2009-08-27 |
| EP1711174A1 (de) | 2006-10-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |