ATE389670T1 - Selektive peptidische agonisten des vpac2- rezeptors - Google Patents

Selektive peptidische agonisten des vpac2- rezeptors

Info

Publication number
ATE389670T1
ATE389670T1 AT05749168T AT05749168T ATE389670T1 AT E389670 T1 ATE389670 T1 AT E389670T1 AT 05749168 T AT05749168 T AT 05749168T AT 05749168 T AT05749168 T AT 05749168T AT E389670 T1 ATE389670 T1 AT E389670T1
Authority
AT
Austria
Prior art keywords
vpac2 receptor
peptidic agonists
selective peptidic
selective
agonists
Prior art date
Application number
AT05749168T
Other languages
English (en)
Inventor
Bengt Krister Bokvist
Robert Cummins
Wolfgang Glaesner
Jesper Lindgren Gromada
John Mayer
Lianshan Zhang
Jorge Alsina-Fernandez
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE389670T1 publication Critical patent/ATE389670T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/57563Vasoactive intestinal peptide [VIP]; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT05749168T 2004-05-21 2005-05-19 Selektive peptidische agonisten des vpac2- rezeptors ATE389670T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US57308004P 2004-05-21 2004-05-21

Publications (1)

Publication Number Publication Date
ATE389670T1 true ATE389670T1 (de) 2008-04-15

Family

ID=34993247

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05749168T ATE389670T1 (de) 2004-05-21 2005-05-19 Selektive peptidische agonisten des vpac2- rezeptors

Country Status (7)

Country Link
US (1) US20080096811A1 (de)
EP (1) EP1753780B1 (de)
AT (1) ATE389670T1 (de)
CA (1) CA2567635A1 (de)
DE (1) DE602005005476T2 (de)
ES (1) ES2302201T3 (de)
WO (1) WO2005113593A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7595294B2 (en) 2004-10-08 2009-09-29 Transition Therapeutics, Inc. Vasoactive intestinal polypeptide pharmaceuticals
US20090170775A1 (en) * 2004-10-08 2009-07-02 Transition Therapeutics, Inc. Vasoactive intestinal polypeptide compositions
BRPI0516126A (pt) 2004-10-08 2008-08-26 Forbes Medi Tech Res Inc produtos farmacêuticos de polipeptìdeos intestinais vasoativos
CA2607273A1 (en) * 2005-05-06 2006-11-16 Bayer Pharmaceuticals Corporation Pituitary adenylate cyclase activating peptide (pacap) receptor (vpac2) agonists and their pharmacological methods of use
CN101296708B (zh) * 2005-10-26 2011-12-07 伊莱利利公司 选择性vpac2受体肽激动剂
NZ623674A (en) * 2005-12-09 2014-07-25 Vectus Biosystems Ltd Vip fragments and methods of use
US20100048460A1 (en) * 2006-02-28 2010-02-25 Lianshan Zhang Selective vpac2 receptor peptide agonists
US9029505B2 (en) * 2009-08-14 2015-05-12 Phasebio Pharmaceuticals, Inc. Modified vasoactive intestinal peptides
CA2873553C (en) 2011-06-06 2020-01-28 Phasebio Pharmaceuticals, Inc. Use of modified vasoactive intestinal peptides in the treatment of hypertension
US11052132B2 (en) * 2014-05-08 2021-07-06 Phasebio Pharmaceuticals, Inc. Methods and compositions for treating cystic fibrosis
CN114652817B (zh) 2015-02-09 2026-04-17 费斯生物制药公司 用于治疗肌肉疾病和病症的方法和组合物
TWI796339B (zh) * 2017-06-27 2023-03-21 大陸商尚華醫藥科技(江西)有限公司 一種肽類化合物、其應用及含其的組合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04193896A (ja) * 1989-10-26 1992-07-13 Meiji Seika Kaisha Ltd 活性ペプチド
JPH0692991A (ja) * 1991-02-28 1994-04-05 Daicel Chem Ind Ltd 新規活性ペプチド
US6242563B1 (en) * 1998-07-20 2001-06-05 Societe De Conseils De Recherches Et D'applications Scientifiques, Sas Peptide analogues
CA2379604A1 (en) * 1999-09-28 2001-04-05 Bayer Corporation Pituitary adenylate cyclase activating peptide (pacap) receptor 3 (r3) agonists and their pharmacological methods of use
PL377025A1 (pl) * 2002-07-12 2006-01-23 Bayer Pharmaceuticals Corporation Agoniści receptora peptydu aktywującego przysadkową cyklazę adenylową (PACAP) -VPAC2 i ich farmakologiczne sposoby zastosowania

Also Published As

Publication number Publication date
US20080096811A1 (en) 2008-04-24
ES2302201T3 (es) 2008-07-01
DE602005005476D1 (de) 2008-04-30
CA2567635A1 (en) 2005-12-01
DE602005005476T2 (de) 2009-03-05
EP1753780B1 (de) 2008-03-19
EP1753780A1 (de) 2007-02-21
WO2005113593A1 (en) 2005-12-01

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties