ATE391787T1 - Verfahren zur herstellung von ubiquinon-10 - Google Patents
Verfahren zur herstellung von ubiquinon-10Info
- Publication number
- ATE391787T1 ATE391787T1 AT00966472T AT00966472T ATE391787T1 AT E391787 T1 ATE391787 T1 AT E391787T1 AT 00966472 T AT00966472 T AT 00966472T AT 00966472 T AT00966472 T AT 00966472T AT E391787 T1 ATE391787 T1 AT E391787T1
- Authority
- AT
- Austria
- Prior art keywords
- property
- microorganisms
- activity
- ubiquinone
- strengthened
- Prior art date
Links
- ACTIUHUUMQJHFO-UHFFFAOYSA-N Coenzym Q10 Natural products COC1=C(OC)C(=O)C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UHFFFAOYSA-N 0.000 title abstract 3
- ACTIUHUUMQJHFO-UPTCCGCDSA-N coenzyme Q10 Chemical compound COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UPTCCGCDSA-N 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 244000005700 microbiome Species 0.000 abstract 4
- 230000000694 effects Effects 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 102000003960 Ligases Human genes 0.000 abstract 1
- 108090000364 Ligases Proteins 0.000 abstract 1
- 238000009395 breeding Methods 0.000 abstract 1
- 230000001488 breeding effect Effects 0.000 abstract 1
- 230000002950 deficient Effects 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/66—Preparation of oxygen-containing organic compounds containing the quinoid structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP29195999 | 1999-10-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE391787T1 true ATE391787T1 (de) | 2008-04-15 |
Family
ID=17775687
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00966472T ATE391787T1 (de) | 1999-10-14 | 2000-10-13 | Verfahren zur herstellung von ubiquinon-10 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7422878B1 (de) |
| EP (1) | EP1227155B1 (de) |
| JP (1) | JP4668495B2 (de) |
| AT (1) | ATE391787T1 (de) |
| AU (1) | AU7686000A (de) |
| CA (3) | CA2385132C (de) |
| DE (1) | DE60038565T2 (de) |
| WO (1) | WO2001027286A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1383864B1 (de) * | 2000-09-29 | 2008-01-16 | Cargill Incorporated | Isoprenoidproduktion |
| TWI305547B (en) | 2001-12-27 | 2009-01-21 | Kaneka Corp | Processes for producing coenzyme q10 |
| CN1751124B (zh) * | 2003-02-19 | 2010-05-12 | 帝斯曼知识产权资产管理有限公司 | CoQ10的微生物生产方法 |
| JP4528297B2 (ja) * | 2003-07-08 | 2010-08-18 | ディーエスエム アイピー アセッツ ビー.ブイ. | コエンザイムq−10の向上した産生 |
| JP2006212019A (ja) * | 2004-04-30 | 2006-08-17 | National Institute Of Agrobiological Sciences | 植物を用いたユビキノン−10の製造方法 |
| DE102005046225B4 (de) | 2005-09-28 | 2012-01-05 | Cellca Gmbh | Verbessertes Zellkulturmedium |
| JP4702025B2 (ja) * | 2005-12-07 | 2011-06-15 | トヨタ自動車株式会社 | 遺伝子組換えによるユビキノン−10の製造方法 |
| EP2004801A2 (de) * | 2006-03-20 | 2008-12-24 | Microbia Precision Engineering | Produktion von chinon abgeleiteten verbindungen in ölhaltigen hefepilzen |
| KR20080047144A (ko) * | 2006-11-24 | 2008-05-28 | 에스케이에너지 주식회사 | 높은 조효소 q10 함량을 갖는 로도박터 스패로이데스sk2h2 균주 및 이를 이용한 조효소 q10의 생산방법 |
| EP2468878A1 (de) * | 2010-12-21 | 2012-06-27 | Sanbo International Establishment | Verfahren zur Steigerung des Gehaltes an CoQ10 und CoQH2 in phototrophen Mikroorganismen |
| CN108795968A (zh) * | 2017-05-03 | 2018-11-13 | 华东理工大学 | 一种类球红细菌高产菌株的遗传转化方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06189775A (ja) | 1992-10-06 | 1994-07-12 | Alpha- Shokuhin Kk | ユビキノン生合成鍵酵素ubiA遺伝子 |
| JPH08107789A (ja) | 1994-10-13 | 1996-04-30 | Alpha- Shokuhin Kk | ユビキノン−10の製造方法 |
| JPH1057072A (ja) * | 1996-08-22 | 1998-03-03 | Alpha- Shokuhin Kk | ユビキノン−10の生成方法 |
| JPH1156372A (ja) * | 1997-08-27 | 1999-03-02 | Alpha- Shokuhin Kk | ユビキノン−10の生成方法 |
| US6225097B1 (en) | 1997-09-17 | 2001-05-01 | Toyota Jidosha Kabushiki Kaisha | Decaprenyl diphosphate synthetase gene |
| JPH11178590A (ja) * | 1997-09-17 | 1999-07-06 | Toyota Motor Corp | デカプレニル二リン酸合成酵素遺伝子 |
| EP1383864B1 (de) * | 2000-09-29 | 2008-01-16 | Cargill Incorporated | Isoprenoidproduktion |
-
2000
- 2000-10-13 DE DE60038565T patent/DE60038565T2/de not_active Expired - Lifetime
- 2000-10-13 CA CA2385132A patent/CA2385132C/en not_active Expired - Fee Related
- 2000-10-13 WO PCT/JP2000/007121 patent/WO2001027286A1/ja not_active Ceased
- 2000-10-13 AU AU76860/00A patent/AU7686000A/en not_active Abandoned
- 2000-10-13 AT AT00966472T patent/ATE391787T1/de not_active IP Right Cessation
- 2000-10-13 CA CA2718652A patent/CA2718652C/en not_active Expired - Fee Related
- 2000-10-13 US US10/110,393 patent/US7422878B1/en not_active Expired - Fee Related
- 2000-10-13 EP EP00966472A patent/EP1227155B1/de not_active Expired - Lifetime
- 2000-10-13 CA CA2722337A patent/CA2722337A1/en not_active Abandoned
- 2000-10-13 JP JP2001530489A patent/JP4668495B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU7686000A (en) | 2001-04-23 |
| CA2385132A1 (en) | 2001-04-19 |
| CA2385132C (en) | 2010-12-14 |
| DE60038565T2 (de) | 2009-06-10 |
| JP4668495B2 (ja) | 2011-04-13 |
| DE60038565D1 (de) | 2008-05-21 |
| CA2718652C (en) | 2014-07-29 |
| EP1227155A4 (de) | 2004-07-28 |
| EP1227155A1 (de) | 2002-07-31 |
| CA2722337A1 (en) | 2001-04-19 |
| EP1227155B1 (de) | 2008-04-09 |
| WO2001027286A1 (en) | 2001-04-19 |
| CA2718652A1 (en) | 2001-04-19 |
| US7422878B1 (en) | 2008-09-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |