ATE393395T1 - Elastinpeptid-fingerabdrücke und analyseverfahren für mit copd in verbindung stehendes mmp12 - Google Patents

Elastinpeptid-fingerabdrücke und analyseverfahren für mit copd in verbindung stehendes mmp12

Info

Publication number
ATE393395T1
ATE393395T1 AT04775479T AT04775479T ATE393395T1 AT E393395 T1 ATE393395 T1 AT E393395T1 AT 04775479 T AT04775479 T AT 04775479T AT 04775479 T AT04775479 T AT 04775479T AT E393395 T1 ATE393395 T1 AT E393395T1
Authority
AT
Austria
Prior art keywords
mmp12
copd
analysis methods
peptide fingerprints
elastin peptide
Prior art date
Application number
AT04775479T
Other languages
English (en)
Inventor
Per Broberg
Thomas Fehniger
Gyoergy Marko-Varga
Stephan Max Uebel
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE393395T1 publication Critical patent/ATE393395T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6884—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from lung
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/12—Pulmonary diseases
    • G01N2800/122—Chronic or obstructive airway disorders, e.g. asthma COPD
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
AT04775479T 2003-09-25 2004-09-24 Elastinpeptid-fingerabdrücke und analyseverfahren für mit copd in verbindung stehendes mmp12 ATE393395T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0302559A SE0302559D0 (sv) 2003-09-25 2003-09-25 Method

Publications (1)

Publication Number Publication Date
ATE393395T1 true ATE393395T1 (de) 2008-05-15

Family

ID=29246968

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04775479T ATE393395T1 (de) 2003-09-25 2004-09-24 Elastinpeptid-fingerabdrücke und analyseverfahren für mit copd in verbindung stehendes mmp12

Country Status (7)

Country Link
US (1) US8012692B2 (de)
EP (1) EP1668372B1 (de)
AT (1) ATE393395T1 (de)
DE (1) DE602004013350T2 (de)
ES (1) ES2303954T3 (de)
SE (1) SE0302559D0 (de)
WO (1) WO2005029090A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100203565A1 (en) * 2005-03-22 2010-08-12 Astrazeneca Ab Peptide Fingerprint from the Degradation of Elastin by HNE
EP4032538A3 (de) 2009-03-02 2022-10-26 Massachusetts Institute of Technology Verfahren und produkte zur in-vivo-enzymprofilierung
ES2881535T3 (es) 2011-03-15 2021-11-29 Massachusetts Inst Technology Detección multiplexada con indicadores codificados con isótopos
HK1221405A1 (zh) * 2013-04-05 2017-06-02 Claudia Zylberberg 基质金属蛋白酶及其用途
JP6847660B2 (ja) 2013-06-07 2021-03-24 マサチューセッツ インスティテュート オブ テクノロジー リガンドをコードする合成バイオマーカーのアフィニティベースの検出
CN105527361B (zh) * 2014-09-29 2017-06-20 上海市计算技术研究所 一种高效微流电色谱相似度分析以及计算影响度的方法
EP3440013A4 (de) 2016-04-08 2021-03-17 Massachusetts Institute of Technology Verfahren zur spezifischen profilierung der protease-aktivität an lymphknoten
WO2017193070A1 (en) 2016-05-05 2017-11-09 Massachusetts Institute Of Technology Methods and uses for remotely triggered protease activity measurements
AU2018248327B2 (en) 2017-04-07 2024-10-10 Massachusetts Institute Of Technology Methods to spatially profile protease activity in tissue and sections
GB201802070D0 (en) * 2018-02-08 2018-03-28 Nordic Bioscience As Elastin assay
WO2019173332A1 (en) 2018-03-05 2019-09-12 Massachusetts Institute Of Technology Inhalable nanosensors with volatile reporters and uses thereof
CN108872442B (zh) * 2018-08-17 2021-04-27 无限极（中国）有限公司 一种基于谱效关系的骨胶原肽质量检测方法
EP3856921B1 (de) 2018-09-25 2026-04-29 Massachusetts Institute Of Technology Lungenprotease nanosensoren und deren verwendungen
EP3911753A1 (de) 2019-01-17 2021-11-24 Massachusetts Institute of Technology Sensoren zur erfassung und abbildung von krebsmetastasen

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2311688A (en) * 1987-08-07 1989-03-09 Graduate Hospital Foundation Research Corporation Immunologic identification of carboxy terminal sequences of elastin in human plasma using monospecific antibodies
US6124107A (en) * 1988-06-10 2000-09-26 Merck & Co., Inc. Assay for marker of human polymorphonuclear leukocyte elastase activity
WO1991018290A1 (en) * 1990-05-11 1991-11-28 Graduate Hospital Foundation Research Corporation Immunoassay of elastin peptides in urine
GB2339200B (en) 1998-06-06 2001-09-12 Genostic Pharma Ltd Genostics
US6797523B2 (en) * 2000-11-30 2004-09-28 Affinium Pharmaceuticals, Inc. Methods for systematic identification of protein—protein interactions
JP4426179B2 (ja) * 2000-12-18 2010-03-03 アライバ ファーマシューティカルズ，インコーポレイティド 多機能性プロテアーゼインヒビターおよびそれらの疾患治療における使用

Also Published As

Publication number Publication date
DE602004013350D1 (de) 2008-06-05
SE0302559D0 (sv) 2003-09-25
US8012692B2 (en) 2011-09-06
DE602004013350T2 (de) 2009-05-20
WO2005029090A1 (en) 2005-03-31
ES2303954T3 (es) 2008-09-01
EP1668372A1 (de) 2006-06-14
US20060292631A1 (en) 2006-12-28
EP1668372B1 (de) 2008-04-23

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