ATE39365T1 - Verfahren zur feststellung der mutagenischen potenz von substanzen, faehig zur induzierung von zellulaerer dns-beschaedigung, unter verwendung der produktion einer sos-antwort. - Google Patents

Verfahren zur feststellung der mutagenischen potenz von substanzen, faehig zur induzierung von zellulaerer dns-beschaedigung, unter verwendung der produktion einer sos-antwort.

Info

Publication number
ATE39365T1
ATE39365T1 AT83401905T AT83401905T ATE39365T1 AT E39365 T1 ATE39365 T1 AT E39365T1 AT 83401905 T AT83401905 T AT 83401905T AT 83401905 T AT83401905 T AT 83401905T AT E39365 T1 ATE39365 T1 AT E39365T1
Authority
AT
Austria
Prior art keywords
enzyme
gene
activity
substance
determining
Prior art date
Application number
AT83401905T
Other languages
English (en)
Inventor
Maurice Hofnung
Philippe Quillardet
David Perrin
Olivier Huisman
Ari Richard D
Original Assignee
Pasteur Institut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pasteur Institut filed Critical Pasteur Institut
Application granted granted Critical
Publication of ATE39365T1 publication Critical patent/ATE39365T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
    • G01N33/5017—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity for testing neoplastic activity
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/848—Escherichia
    • Y10S435/849—Escherichia coli

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
AT83401905T 1982-09-28 1983-09-28 Verfahren zur feststellung der mutagenischen potenz von substanzen, faehig zur induzierung von zellulaerer dns-beschaedigung, unter verwendung der produktion einer sos-antwort. ATE39365T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8216316A FR2533584B1 (fr) 1982-09-28 1982-09-28 Procede de detection du pouvoir mutagene de substances, susceptibles d'induire la deterioration d'adn cellulaires, mettant en jeu la production d'une reponse sos
EP83401905A EP0106749B1 (de) 1982-09-28 1983-09-28 Verfahren zur Feststellung der mutagenischen Potenz von Substanzen, fähig zur Induzierung von zellulärer DNS-Beschädigung, unter Verwendung der Produktion einer SOS-Antwort

Publications (1)

Publication Number Publication Date
ATE39365T1 true ATE39365T1 (de) 1989-01-15

Family

ID=9277812

Family Applications (1)

Application Number Title Priority Date Filing Date
AT83401905T ATE39365T1 (de) 1982-09-28 1983-09-28 Verfahren zur feststellung der mutagenischen potenz von substanzen, faehig zur induzierung von zellulaerer dns-beschaedigung, unter verwendung der produktion einer sos-antwort.

Country Status (8)

Country Link
US (1) US4849335A (de)
EP (1) EP0106749B1 (de)
JP (2) JPS59501773A (de)
AT (1) ATE39365T1 (de)
CA (1) CA1222212A (de)
DE (1) DE3378733D1 (de)
FR (1) FR2533584B1 (de)
WO (1) WO1984001388A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7793587A (en) * 1986-09-05 1988-03-10 Medical Research Council Mammalian cell mutagenicity screening test
KR100300932B1 (ko) * 1992-07-06 2001-10-22 조이스 브린톤 리포터유전자에융합된세균의스트레스프로모터를이용하여독성을측정하는방법및진단키트
US5674992A (en) * 1992-08-28 1997-10-07 Cornell Research Foundation, Inc. CDNA encoding a recA homolog in eukaryotes
HK1004920A1 (en) * 1993-01-21 1998-12-11 President And Fellows Of Harvard College Methods and diagnostic kits utilizing mammalian stress promoters to determine toxicity of a compound
EP0649905B1 (de) * 1993-10-22 1998-09-23 Kabushiki Kaisha Toyota Chuo Kenkyusho Verfahren zum Nachweis von Mutagenen unter Verwendung eines Lumineszensgens
JP4371432B2 (ja) 1996-04-25 2009-11-25 ヴラームス インステリング ヴール テクノロギシュ オンデルゾーク （ヴイアイティーオー） サンプルの遺伝毒性及び変異原性の両方、及び遺伝毒性の速度を測定するための組換え核酸配列及び方法
US6602666B2 (en) 1998-12-02 2003-08-05 Vlaamse Instelling Technologisch Onderzoek (V.I.T.O.) Recombinant nucleic acid sequences and methods for determining both genotoxicity and mutagenicity of a sample and the kinetics of the genotoxicity
EE04780B1 (et) 1999-06-02 2007-02-15 Janssen Pharmaceutica N.V. Aminoalküül-asendatud bensodioksaani, bensofuraani või bensopüraani derivaadid, nende valmistamismeetod, farmatseutiline kompositsioon ja selle valmistamismeetod
SK286159B6 (sk) 1999-06-02 2008-04-07 Janssen Pharmaceutica N. V. Benzodioxánový, benzofuránový alebo benzopyránovýderivát, spôsob jeho prípravy, tento derivát na použitie ako liečivo, farmaceutická kompozícia obsahujúca tento derivát a spôsob jej prípravy
US20080288384A1 (en) * 2007-05-17 2008-11-20 Stephen John Collins System for automatic financial transaction notifications over wireless network or other network

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3279823D1 (en) * 1981-04-14 1989-08-24 Pasteur Institut An inducible dna replication-cell division coupling mechanism in escherichia coli

Also Published As

Publication number Publication date
EP0106749B1 (de) 1988-12-21
DE3378733D1 (en) 1989-01-26
CA1222212A (fr) 1987-05-26
WO1984001388A1 (fr) 1984-04-12
EP0106749A1 (de) 1984-04-25
JPH05211865A (ja) 1993-08-24
FR2533584A1 (fr) 1984-03-30
JPS59501773A (ja) 1984-10-25
FR2533584B1 (fr) 1986-03-21
US4849335A (en) 1989-07-18
JPH0412118B2 (de) 1992-03-03

Similar Documents

Publication Publication Date Title
ES8900021A1 (es) Un metodo de replicar en un sistema huesped microbiano una proteina biologicamente funcional, codificada por una secuencia de adn
DE68925083D1 (de) Rekombinante DNS, diese rekombinante DNS enthaltender Mikroorganismus und Verfahren zur Herstellung von L-Aminosäure unter Verwendung dieses Mikroorganismus
FI883082A0 (fi) Konstruering av syntetisk dna och dess anvaendning i syntes av stora polypeptider.
ATE92030T1 (de) Verfahren zur herstellung von vinylacetat.
ATE39365T1 (de) Verfahren zur feststellung der mutagenischen potenz von substanzen, faehig zur induzierung von zellulaerer dns-beschaedigung, unter verwendung der produktion einer sos-antwort.
DE3751923D1 (de) Verfahren zur Klonierung von Restriktions-Modifikationssystemen
DE3687953D1 (de) Verfahren zur herstellung von tintenmassen fuer tintenstrahlschreiber.
DE68920663D1 (de) Verfahren zur Herstellung von Hefeextrakt, Hefeextrakt, seine Verwendung als Würzstoff und Nahrungsmittel, das den Hefeextrakt enthält.
DE69115592D1 (de) Verfahren zur Verbrennung mit verbesserter Spaltung von verunreinigten Säuren
AT376697B (de) Verfahren zur kontinuierlichen vergaerung von waesseriger maische fuer die gewinnung von ethanol und hefe-biomasse
AT358513B (de) Verfahren zur fermentierung von mikro- organismen
DE69011880D1 (de) Verfahren zur Herstellung von L-Aminosäuren durch Fermentation.
DE68906904D1 (de) Verfahren zur herstellung von optisch aktiven 2-arylalkansaeuren.
DE3878747D1 (de) Verfahren zur herstellung von 2-keto-l-gulonsaeure.
DE3583171D1 (de) Verfahren zur herstellung von kohlenstoffkoerpern.
DE59007810D1 (de) Verfahren zur enzymatischen Spaltung von 2-Arylpropionsäurevinylestern.
DE59206633D1 (de) Biotechnologisches Verfahren zur Herstellung von S-(+)-2,2-Dimethylcyclopropancarboxamid und R-(-)-2,2-Dimethylcyclopropancarbonsäure
DE69014044D1 (de) Neue alkylische Pullulanase Y mit alpha-Amylase-Aktivität, sie produzierender Mikroorganismus und Verfahren zur Herstellung dieses Enzyms.
ATE20761T1 (de) Verfahren zur herstellung saurer protease.
DE3685337D1 (de) Verfahren zur herstellung von amiden unter verwendung von mikroorganismen.
AT374494B (de) Verfahren zur anreicherung von mikroorganismenbiomasse
ATE4326T1 (de) Verfahren zur gewinnung von cholesterinesterase.
DE3673686D1 (de) Immobilisierte maltooligosaccharid-bildende amylase und verfahren zur herstellung von maltooligosaccharid unter verwendung des genannten enzyms.
ZA763893B (en) Method for the culture of monocellular microorganisms and microorganism obtained thereby
ATE145670T1 (de) Verfahren zur fermentativen herstellung von 2- hydroxyphenylessigsäure

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee