ATE394365T1 - Verfahren zur synthese von verbindungen vom ceramidtyp - Google Patents

Verfahren zur synthese von verbindungen vom ceramidtyp

Info

Publication number
ATE394365T1
ATE394365T1 AT04767243T AT04767243T ATE394365T1 AT E394365 T1 ATE394365 T1 AT E394365T1 AT 04767243 T AT04767243 T AT 04767243T AT 04767243 T AT04767243 T AT 04767243T AT E394365 T1 ATE394365 T1 AT E394365T1
Authority
AT
Austria
Prior art keywords
synthesis
ceramide
specifically
type compounds
fields
Prior art date
Application number
AT04767243T
Other languages
English (en)
Inventor
Laurent Lassalle
Florent Yvergnaux
Original Assignee
Biochimie Appliquee Sa Solabia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biochimie Appliquee Sa Solabia filed Critical Biochimie Appliquee Sa Solabia
Application granted granted Critical
Publication of ATE394365T1 publication Critical patent/ATE394365T1/de

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/68—Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/20—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a carbon atom of an acyclic unsaturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/08—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/12—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT04767243T 2003-06-03 2004-06-03 Verfahren zur synthese von verbindungen vom ceramidtyp ATE394365T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0306661A FR2855823B1 (fr) 2003-06-03 2003-06-03 Nouveaux composes de type ceramide, leur procede de synthese, et compositions cosmetiques et/ou pharmaceutiques en contenant

Publications (1)

Publication Number Publication Date
ATE394365T1 true ATE394365T1 (de) 2008-05-15

Family

ID=33443104

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04767243T ATE394365T1 (de) 2003-06-03 2004-06-03 Verfahren zur synthese von verbindungen vom ceramidtyp

Country Status (8)

Country Link
US (1) US7344868B2 (de)
EP (1) EP1644318B1 (de)
JP (1) JP4638413B2 (de)
KR (1) KR101129996B1 (de)
AT (1) ATE394365T1 (de)
DE (1) DE602004013590D1 (de)
FR (1) FR2855823B1 (de)
WO (1) WO2004108659A1 (de)

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FR2908299B1 (fr) * 2006-11-10 2010-08-27 Biochimie Appliquee Soc Compositions cosmetiques et/ou dermatologiques contenant un derive d'acide gras et leurs utilisations
FR2908308B1 (fr) * 2006-11-10 2016-12-02 Soc La Biochimie Appliquee Compositions cosmetiques et/ou dermatologiques contenant un pseudo-ceramide et leur utilisation contre le stress cutane
FR2909378B1 (fr) * 2006-12-05 2012-01-13 Biochimie Appliquee Soc Ceramides ou pseudo-ceramides quaternises et les compositions cosmetiques en contenant
FR2924428A1 (fr) * 2007-02-15 2009-06-05 Biochimie Appliquee Sa Soc Pseudo-ceramides derives d'huiles vegetales et les compositions cosmetiques et/ou dermatologiques en contenant
US8816110B2 (en) * 2007-02-15 2014-08-26 Scf Pharma Inc. Polyunsaturated fatty acid monoglycerides, derivatives, and uses thereof
EP2136844B1 (de) 2007-03-20 2018-10-31 SCF Pharma Inc. Zusammensetzungen mit mehrfach ungesättigten fettsäuremonoglyceriden oder derivaten davon und ihre verwendung
FR2922102B1 (fr) * 2007-10-11 2013-02-15 Biochimie Appliquee Solabia Soc Compositions cosmetiques et/ou dermatologiques et leur utilisation pour la depigmentation
FR2926462B1 (fr) * 2008-01-22 2016-06-24 Soc La Biochimie Appliquee Compositions cosmetiques et/ou dermatologiques contenant des inhibiteurs d'elastase
FR2926725B1 (fr) * 2008-01-25 2010-09-03 Biochimie Appliquee Soc Compositions cosmetiques et/ou dermatologiques cicatrisantes
DE102008002410A1 (de) * 2008-06-13 2009-12-17 Evonik Goldschmidt Gmbh Enzymatische Synthese von Sphingolipiden
DE102008002409A1 (de) * 2008-06-13 2009-12-17 Evonik Goldschmidt Gmbh Enzymatische Synthese von Sphingolipiden
EP2233128A1 (de) * 2009-03-25 2010-09-29 Cognis IP Management GmbH Kosmetische Zusammensetzung
FR2966041B1 (fr) * 2010-10-18 2025-11-14 La Biochimie Appliquee Solabia Nouvelles compositions capillaires et leurs utilisations
US9861702B2 (en) 2012-10-22 2018-01-09 Wisconsin Alumni Research Foundation Lipid-conjugated rhamnose for immune system recruitment and oncotherapy
KR102014964B1 (ko) * 2012-11-30 2019-08-28 (주)아모레퍼시픽 신규한 유사 세라마이드 화합물 및 그 제조방법
KR102088802B1 (ko) * 2012-11-30 2020-03-16 (주)아모레퍼시픽 신규한 유사 세라마이드 화합물 및 그 제조방법
KR101338237B1 (ko) 2013-08-23 2013-12-06 주식회사 더마랩 세라마이드 유사 화합물, 이의 제조방법 및 이를 포함하는 화장료 조성물
KR101510683B1 (ko) 2013-09-03 2015-04-10 (주)네오팜 카나비노이드 수용체에 길항작용을 가지는 신규한 유사 세라마이드 유도체 및 이를 포함하는 약학 또는 화장품 조성물
US9447020B2 (en) 2013-10-31 2016-09-20 Scf Pharma Inc. Polyunsaturated fatty acid monoglycerides, derivatives, and uses thereof
KR101545527B1 (ko) * 2014-01-13 2015-08-19 (주)네오팜 신규한 유사 세라마이드 화합물, 이를 포함하는 약학 조성물 및 화장료 조성물
KR101681654B1 (ko) * 2014-10-31 2016-12-01 한국과학기술연구원 효소적 위치선택반응에 의한 디아세틸세라마이드 유도체의 제조방법
KR101641702B1 (ko) * 2014-11-14 2016-07-21 애경산업(주) 신규 유사세라마이드 화합물 및 이를 포함하는 조성물
CN107405305B (zh) * 2015-01-20 2020-12-25 泰特拉德姆集团有限责任公司 提供粘膜和皮肤屏障恢复的通用局部药物递送载体和多因子组织保湿剂
KR101809614B1 (ko) 2017-09-08 2017-12-15 (주)삼경코스텍 이소세리놀 아미드 유도체 및 이를 포함하는 조성물
CN111971041A (zh) 2018-02-07 2020-11-20 Scf制药股份有限公司 多不饱和脂肪酸单甘油酯、组合物、方法及其用途
CN112384212A (zh) 2018-05-03 2021-02-19 Scf制药股份有限公司 多不饱和脂肪酸单甘油酯、其组合物、方法和用途
US12226390B2 (en) 2019-07-21 2025-02-18 Scf Pharma Inc. Cannabinoids compositions with polyunsaturated fatty acid monoglycerides, methods and uses thereof
KR102225519B1 (ko) * 2019-09-05 2021-03-11 한국생명공학연구원 칸디다 안타티카 리파제 b의 변이체 및 이의 이용
KR102254208B1 (ko) * 2019-09-27 2021-05-21 주식회사 대한뷰티산업진흥원 효소촉매 리파제로 제조된 제주 천연오일 유래의 유사세라마이드 복합체 및 이를 포함하는 기능성 화장품 원료
AU2020375734B2 (en) * 2019-10-28 2026-04-09 Geron Corporation Crystalline solids of 3-palmitoyl-amido-1,2-propanediol and 3-palmitoyl-amido-2-hydroxy-1-dimethoxytriphenylmethylether-propane and methods of making and using the same
KR102861357B1 (ko) 2019-10-28 2025-09-18 제론 코포레이션 비정질 고체 석신일화 3-(지방산 아미도)-2-하이드록시-1-(보호된 하이드록시)-프로판 염 및 이를 제조하는 방법
KR102301101B1 (ko) * 2021-04-05 2021-09-09 박명화 천연 오일 및 천연 추출물을 포함하는 화장료 조성물
CN120923366A (zh) * 2025-10-10 2025-11-11 重庆智合生物医药有限公司 基于长链脂肪酸的神经酰胺化合物的合成控制方法及系统

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FR2780727B1 (fr) * 1998-07-03 2000-09-08 Atochem Elf Sa Compositions cosmetiques, nouveaux analogues de ceramides a activite anti-elastase, procede de preparation et utilisations
JP3886738B2 (ja) * 2001-05-24 2007-02-28 花王株式会社 洗浄剤組成物
JP4030746B2 (ja) * 2001-11-14 2008-01-09 花王株式会社 パール光沢付与剤

Also Published As

Publication number Publication date
US20060121583A1 (en) 2006-06-08
KR101129996B1 (ko) 2012-04-23
WO2004108659A1 (fr) 2004-12-16
JP2006526400A (ja) 2006-11-24
US7344868B2 (en) 2008-03-18
EP1644318A1 (de) 2006-04-12
DE602004013590D1 (de) 2008-06-19
KR20060027322A (ko) 2006-03-27
JP4638413B2 (ja) 2011-02-23
FR2855823A1 (fr) 2004-12-10
FR2855823B1 (fr) 2007-09-21
EP1644318B1 (de) 2008-05-07

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