ATE394423T1 - Analoge des glucagon ähnlichen peptides-1 (glp-1) - Google Patents

Analoge des glucagon ähnlichen peptides-1 (glp-1)

Info

Publication number: ATE394423T1
Authority: AT; Austria
Prior art keywords: peptide; glucagon; glp; analogue; analogues
Prior art date: 1998-12-07

Application number

AT99960657T

Other languages

English (en)

Inventor

Zheng Dong

David Coy

Original Assignee

Sod Conseils Rech Applic

Univ Tulane

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-12-07

Filing date

1999-12-07

Publication date

2008-05-15

1999-12-07 Application filed by Sod Conseils Rech Applic, Univ Tulane filed Critical Sod Conseils Rech Applic

2008-05-15 Application granted granted Critical

2008-05-15 Publication of ATE394423T1 publication Critical patent/ATE394423T1/de

Links

GCYXWQUSHADNBF-AAEALURTSA-N preproglucagon 78-108 Chemical class C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC=1N=CNC=1)[C@@H](C)O)[C@@H](C)O)C(C)C)C1=CC=CC=C1 GCYXWQUSHADNBF-AAEALURTSA-N 0.000 title 1
DTHNMHAUYICORS-KTKZVXAJSA-N Glucagon-like peptide 1 Chemical class C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC=1N=CNC=1)[C@@H](C)O)[C@@H](C)O)C(C)C)C1=CC=CC=C1 DTHNMHAUYICORS-KTKZVXAJSA-N 0.000 abstract 1
241000124008 Mammalia Species 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Physical Education & Sports Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Hematology (AREA)
Cardiology (AREA)
Obesity (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Orthopedic Medicine & Surgery (AREA)
Heart & Thoracic Surgery (AREA)
Rheumatology (AREA)
Zoology (AREA)
Toxicology (AREA)
Hospice & Palliative Care (AREA)
Emergency Medicine (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Child & Adolescent Psychology (AREA)

AT99960657T 1998-12-07 1999-12-07 Analoge des glucagon ähnlichen peptides-1 (glp-1) ATE394423T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US11118698P	1998-12-07	1998-12-07
US20683398A	1998-12-07	1998-12-07

Publications (1)

Publication Number	Publication Date
ATE394423T1 true ATE394423T1 (de)	2008-05-15

Family

ID=26808707

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99960657T ATE394423T1 (de)	1998-12-07	1999-12-07	Analoge des glucagon ähnlichen peptides-1 (glp-1)

Country Status (21)

Country	Link
US (2)	US7368427B1 (de)
EP (2)	EP1137666B9 (de)
JP (3)	JP2002538081A (de)
KR (1)	KR100458748B1 (de)
CN (2)	CN101108878B (de)
AT (1)	ATE394423T1 (de)
AU (1)	AU770609B2 (de)
BR (1)	BR9916027A (de)
CA (1)	CA2352573C (de)
CZ (2)	CZ303399B6 (de)
DE (1)	DE69938669D1 (de)
DK (1)	DK1137666T5 (de)
ES (1)	ES2302390T3 (de)
HU (1)	HUP0104579A3 (de)
IL (2)	IL143481A0 (de)
NO (2)	NO330293B1 (de)
PL (3)	PL205713B1 (de)
PT (1)	PT1137666E (de)
RU (1)	RU2208015C2 (de)
TW (2)	TWI339208B (de)
WO (1)	WO2000034332A1 (de)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
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WO2000034331A2 (en)	1998-12-07	2000-06-15	Societe De Conseils De Recherches Et D'applications Scientifiques Sas	Analogues of glp-1
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US7186683B2 (en)	2000-09-18	2007-03-06	Sanos Bioscience A/S	Use of GLP for the treatment, prevention, diagnosis, and prognosis of bone-related and nutrition-related disorders
US7371721B2 (en)	2000-09-18	2008-05-13	Sanos Bioscience A/S	Use of GLP-2 and related compounds for the treatment, prevention, diagnosis, and prognosis of bone-related disorders and calcium homeostasis related syndromes
WO2002022151A2 (en) *	2000-09-18	2002-03-21	Osteometer Bio Tech A/S	Use of glp-1 and flp-2 peptides for treatment of bone disorders
WO2002034285A2 (en)	2000-10-20	2002-05-02	Coolidge Thomas R	Treatment of hibernating myocardium and diabetic cardiomyopathy with a glp-1 peptide
EP1346722B1 (de)	2000-12-01	2008-12-10	Takeda Pharmaceutical Company Limited	Verfahren zur herstellung einer zubereitung mit einer bioaktiven substanz
JP2005501058A (ja)	2001-07-31	2005-01-13	ザガバメントオブザユナイテッドステイツオブアメリカアズリプレゼンテッドバイザセクレタリーデパートメントオブヘルスアンドヒューマンサービシーズザナショナルインステ	Ｇｌｐ−１、ｅｘｅｎｄｉｎ−４、そのペプチド・アナログ及びその使用
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US7008957B2 (en)	2003-07-25	2006-03-07	Sanofi-Aventis Deutschland Gmbh	Bicyclic cyanoheterocycles, process for their preparation and their use as medicaments
US7094800B2 (en)	2003-07-25	2006-08-22	Sanofi-Aventis Deutschland Gmbh	Cyanopyrrolidides, process for their preparation and their use as medicaments
US7094794B2 (en)	2003-07-28	2006-08-22	Sanofi-Aventis Deutschland Gmbh	Substituted thiazole-benzoisothiazole dioxide derivatives, process for their preparation and their use
DE10335092B3 (de)	2003-08-01	2005-02-03	Aventis Pharma Deutschland Gmbh	Substituierte Benzoylureido-o-benzoylamide, Verfahren zu deren Herstellung und deren Verwendung
EP1711523B1 (de)	2003-12-16	2012-10-10	Ipsen Pharma	Glp-1-analoga
CA2550695A1 (en) *	2003-12-16	2005-06-30	Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R	Glp-1 pharmaceutical compositions
AU2005203925A1 (en) *	2004-01-08	2005-07-21	Theratechnologies Inc.	Glucagon-Like Peptide-1 analogs with long duration of action
US7534763B2 (en)	2004-07-02	2009-05-19	Bristol-Myers Squibb Company	Sustained release GLP-1 receptor modulators
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EP2364735A3 (de)	2005-12-16	2012-04-11	Nektar Therapeutics	Verzweigte PEG-Kon jugate von GLP-1
AU2007240313B2 (en)	2006-04-20	2012-02-02	Amgen Inc.	GLP-1 compounds
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CN101578102B (zh) *	2007-01-05	2013-07-17	印第安纳大学研究及科技有限公司	在生理性pH缓冲液中显示增强的溶解性的胰高血糖素类似物
JP2010538069A (ja) *	2007-09-07	2010-12-09	イプセンファルマソシエテパールアクシオンサンプリフィエ	エキセンディン−４およびエキセンディン−３の類似体
TWI541023B (zh) *	2008-06-17	2016-07-11	印第安納大學科技研究公司	在生理ｐｈ緩衝液中呈現增強之溶解度及穩定性之升糖激素類似物
WO2010076809A2 (en) *	2008-12-29	2010-07-08	Panacea Biotec Ltd	Glp-1 analogs and uses thereof
MX2012014576A (es) *	2010-06-24	2013-02-21	Univ Indiana Res & Tech Corp	Profarmacos de peptido de la superfamilia de glucagon basado en amida.
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EP2713722B1 (de)	2011-05-31	2017-03-15	Receptos, LLC	Neue glp-1-rezeptor-stabilisatoren und -modulatoren
ES2836973T3 (es)	2011-12-12	2021-06-28	Receptos Llc	Derivados de ácido carboxílico que comprenden cuatro ciclos que actúan como moduladores de receptor GLP-1 para la terapia de enfermedades tales como la diabetes
CN102584982B (zh) *	2012-02-10	2014-02-05	深圳翰宇药业股份有限公司	一种纯化固相合成利拉鲁肽粗肽的方法
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JP2018012644A (ja) *	2014-11-26	2018-01-25	武田薬品工業株式会社	ペプチド化合物
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HK1249847A1 (zh)	2015-03-09	2018-11-16	Intekrin Therapeutics, Inc.	用於治疗非酒精性脂肪肝疾病和/或脂肪营养不良的方法
CR20180378A (es)	2015-12-23	2018-12-06	Amgen Inc	Método para tratar o mejorar trastornos metabólicos con proteínas de unión para el receptor peptídico inhibidor gástrico (gipr) en combinación con agosnistas de glp-1
EP3393496B1 (de)	2015-12-23	2023-10-11	The Johns Hopkins University	Langwirkender glp-1r-agonist als therapie neurologischer und neurodegenerativer erkrankungen
EP3467106B1 (de)	2016-05-24	2025-07-09	Takeda Pharmaceutical Company Limited	Peptidverbindung
JP2019520336A (ja) *	2016-06-02	2019-07-18	インディアナユニヴァーシティリサーチアンドテクノロジーコーポレイション	水溶性で化学的に安定なグルカゴンペプチド
KR102781241B1 (ko)	2017-01-17	2025-03-14	암젠 인크	위 저해 펩타이드 수용체(gipr)에 대한 길항제에 접합된 glp-1 수용체 작용제를 사용하여 대사 장애를 치료 또는 개선하는 방법
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1999
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Publication number	Publication date
WO2000034332A1 (en)	2000-06-15
AU1751200A (en)	2000-06-26
JP2002538081A (ja)	2002-11-12
ES2302390T3 (es)	2008-07-01
NO20100307L (no)	2001-08-06
DK1137666T5 (da)	2009-10-05
US7368427B1 (en)	2008-05-06
EP1137666B9 (de)	2009-04-01
JP2010001301A (ja)	2010-01-07
CN101108878B (zh)	2012-08-29
TWI262925B (en)	2006-10-01
TWI339208B (en)	2011-03-21
PL393611A1 (pl)	2011-05-09
IL143481A (en)	2010-02-17
RU2208015C2 (ru)	2003-07-10
DE69938669D1 (de)	2008-06-19
CZ303399B6 (cs)	2012-08-29
NO20012787D0 (no)	2001-06-06
NO20012787L (no)	2001-08-06
TW200628489A (en)	2006-08-16
AU770609B2 (en)	2004-02-26
PT1137666E (pt)	2008-06-02
PL208751B1 (pl)	2011-06-30
CZ303120B6 (cs)	2012-04-11
HUP0104579A3 (en)	2002-05-28
EP1992641A3 (de)	2009-07-29
CN101108878A (zh)	2008-01-23
DK1137666T3 (da)	2008-09-08
EP1137666B1 (de)	2008-05-07
CN1342166A (zh)	2002-03-27
CA2352573C (en)	2012-04-10
IL143481A0 (en)	2002-04-21
CZ20011895A3 (cs)	2001-12-12
CN100334109C (zh)	2007-08-29
US20090149378A1 (en)	2009-06-11
BR9916027A (pt)	2001-08-28
CA2352573A1 (en)	2000-06-15
JP2006077022A (ja)	2006-03-23
NO330293B1 (no)	2011-03-21
KR20010102953A (ko)	2001-11-17
EP1137666A1 (de)	2001-10-04
EP1992641A2 (de)	2008-11-19
PL205713B1 (pl)	2010-05-31
KR100458748B1 (ko)	2004-12-03
HUP0104579A2 (hu)	2002-04-29

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Publication	Publication Date	Title
DE69938669D1 (de)	2008-06-19	Analoge des glucagon ähnlichen peptides-1 (glp-1)
ATE282635T1 (de)	2004-12-15	Glp-1 analoge
EA200300026A1 (ru)	2003-04-24	Аналоги глюкагоноподобного пептида-1
WO2004074315A3 (en)	2004-11-25	Analogues of glp-1
EP1411968A4 (de)	2005-06-15	Glp 1 exendin 4 peptidanaloga und deren verwendungen
ATE522226T1 (de)	2011-09-15	Verfahren und zusammensetzungen zur behandlung des polyzystischen ovarialsyndroms
DE69719798D1 (de)	2003-04-17	Periphäre verabreichung von glp-1 analogen und derivate zur reguleirung der fettleibigkeit
ATE169225T1 (de)	1998-08-15	Anwendung von urodilatin bei lungen- und bronchialerkrankungen
EP2210900A3 (de)	2010-08-11	GlLP-1-Analoga
TW200740456A (en)	2007-11-01	GLP-1 pharmaceutical compositions
EP1359159A3 (de)	2004-07-21	GLP-1 Analoge
PT1103270E (pt)	2003-08-29	Tratamento de doencas auto-imunes em mamiferos
UA88862C2 (en)	2009-12-10	Glucagon-like peptide-1 analogs
AR021575A1 (es)	2002-07-24	Analogo de glp-1