ATE394475T1 - Methode zur herstellung von infektiösem reovirus - Google Patents

Methode zur herstellung von infektiösem reovirus

Info

Publication number
ATE394475T1
ATE394475T1 AT05009952T AT05009952T ATE394475T1 AT E394475 T1 ATE394475 T1 AT E394475T1 AT 05009952 T AT05009952 T AT 05009952T AT 05009952 T AT05009952 T AT 05009952T AT E394475 T1 ATE394475 T1 AT E394475T1
Authority
AT
Austria
Prior art keywords
producing infectious
infectious reovirus
reovirus
producing
infectious
Prior art date
Application number
AT05009952T
Other languages
English (en)
Inventor
Matthew C Coffey
Bradley G Thompson
Original Assignee
Oncolytics Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncolytics Biotech Inc filed Critical Oncolytics Biotech Inc
Application granted granted Critical
Publication of ATE394475T1 publication Critical patent/ATE394475T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/76Viruses; Subviral particles; Bacteriophages
    • A61K35/765Reovirus; Rotavirus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • C12N2510/02Cells for production
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • C12N2720/12032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • C12N2720/12051Methods of production or purification of viral material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT05009952T 2000-08-10 2001-07-20 Methode zur herstellung von infektiösem reovirus ATE394475T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US22402600P 2000-08-10 2000-08-10

Publications (1)

Publication Number Publication Date
ATE394475T1 true ATE394475T1 (de) 2008-05-15

Family

ID=22838987

Family Applications (2)

Application Number Title Priority Date Filing Date
AT05009952T ATE394475T1 (de) 2000-08-10 2001-07-20 Methode zur herstellung von infektiösem reovirus
AT01953084T ATE298788T1 (de) 2000-08-10 2001-07-20 Verfahren zur herstellung von infektiösen reoviren

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT01953084T ATE298788T1 (de) 2000-08-10 2001-07-20 Verfahren zur herstellung von infektiösen reoviren

Country Status (18)

Country Link
US (4) US6528305B2 (de)
EP (2) EP1586634B1 (de)
JP (2) JP4009532B2 (de)
AR (1) AR033993A1 (de)
AT (2) ATE394475T1 (de)
AU (2) AU7562801A (de)
BR (1) BR0113122A (de)
CA (1) CA2415749C (de)
DE (2) DE60133947D1 (de)
DK (2) DK1309672T3 (de)
ES (2) ES2305940T3 (de)
IL (2) IL153847A0 (de)
MX (1) MXPA03000846A (de)
NZ (1) NZ523510A (de)
PT (2) PT1309672E (de)
TW (1) TWI289158B (de)
WO (1) WO2002012435A1 (de)
ZA (1) ZA200300410B (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6545492B1 (en) * 1999-09-20 2003-04-08 Europaisches Laboratorium Fur Molekularbiologie (Embl) Multiple local probe measuring device and method
TWI289158B (en) * 2000-08-10 2007-11-01 Oncolytics Biotech Inc Method of producing infectious reovirus
DK2253701T3 (da) 2001-03-16 2014-10-20 Oncolytics Biotech Inc Fremgangsmåde til ekstraktion af en virus fra en cellekultur
US20040115170A1 (en) * 2001-11-30 2004-06-17 Brown Earl Garnet Oncolytic virus
US20040005546A1 (en) 2002-02-28 2004-01-08 Oncolytics Biotech Inc. Use of ribozymes in the detection of adventitious agents
CA2374388C (en) 2002-02-28 2005-07-12 Matthew C. Coffey The use of ribozymes in the detection of adventitious agents
WO2003093460A1 (en) * 2002-04-29 2003-11-13 The Trustees Of The University Of Pennsylvania Method for direct rescue and amplification of integrated viruses from cellular dna of tissues
JP2005523722A (ja) 2002-04-30 2005-08-11 オンコリティクス バイオテック, インコーポレイティッド 改善されたウイルス精製方法
WO2003094938A1 (en) * 2002-05-09 2003-11-20 Oncolytics Biotech Inc. Method for reducing pain using oncolytic viruses
EP1944035A1 (de) 2002-05-09 2008-07-16 Oncolytics Biotech Inc. Verfahren zur Schmerzlinderung durch onkolytische Viren
PT1505993E (pt) * 2002-05-10 2012-05-15 Oncolytics Biotech Inc Sensibilização de células neoplásicas a terapia de radiação com vírus oncolíticos
US7901921B2 (en) 2004-10-22 2011-03-08 Oncolytics Biotech Inc. Viral purification methods
US7600514B2 (en) * 2005-06-17 2009-10-13 Nellcor Puritan Bennett Llc System and method for securing a gas delivery mask onto a subject's head
US10668119B2 (en) 2005-08-01 2020-06-02 Virocure, Inc. Attenuated reovirus
WO2007099401A2 (en) 2005-08-01 2007-09-07 University Technologies International, Inc. Oncolytic attenuated reoviruses for treatment of proliferative disorders
AU2007215328A1 (en) * 2006-02-13 2007-08-23 Oncolytics Biotech Inc. Use of local immune suppression to enhance oncolytic viral therapy
US8293498B2 (en) 2006-12-20 2012-10-23 Vanderbilt University System for generation of viable reovirus from cloned cDNA
US20100322951A1 (en) * 2006-12-29 2010-12-23 Bacilligen, Inc. Replication-proficient dsRNA capsids and uses thereof
JP5577103B2 (ja) * 2007-03-12 2014-08-20 オンコリティクス バイオテク,インコーポレーテッド 改変配列を有するレオウイルス
US10369171B2 (en) 2007-03-13 2019-08-06 Virocure, Inc. Attenuated reoviruses for selection of cell populations
AR066649A1 (es) * 2007-05-21 2009-09-02 Oncolytics Biotech Inc Reovirus mutantes y metodos de elaboracion y uso de los mismos
EP2211880A4 (de) * 2007-10-22 2012-11-14 Oncolytics Biotech Inc Behandlungsverfahren für proliferative erkrankungen
US8470312B2 (en) * 2008-05-27 2013-06-25 Oncolytics Biotech, Inc. Abrogating proinflammatory cytokine production during oncolytic reovirus therapy
TW200951143A (en) * 2008-05-27 2009-12-16 Oncolytics Biotech Inc Modulating interstitial pressure and oncolytic viral delivery and distribution
US9249195B2 (en) 2010-04-07 2016-02-02 Vanderbilt University Reovirus vaccines and methods of use therefor
JP2013523175A (ja) 2010-04-14 2013-06-17 イーエムディー・ミリポア・コーポレーション 高力価、高純度のウイルスストックの作製方法及びその使用方法
CN103269716B (zh) * 2010-12-02 2015-05-27 昂科利蒂克斯生物科技公司 冻干病毒制剂
WO2012075379A2 (en) 2010-12-02 2012-06-07 Oncolytics Biotech Inc. Liquid viral formulations
WO2015070323A1 (en) 2013-11-15 2015-05-21 Oncolytics Biotech Inc. Oncolytic viruses and increased cancer treatment regimens
CN112143693B (zh) * 2019-06-28 2024-12-27 杭州康万达医药科技有限公司 一种生产病毒的方法及收获液组合物

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4070453A (en) * 1976-06-25 1978-01-24 Syntex (U.S.A.) Inc. Diploid porcine embryonic cell strains, cultures produced therefrom, and use of said cultures for production of vaccines
US4559229A (en) * 1982-07-20 1985-12-17 Research Foundation Avian proventriculitis vaccine
US5023252A (en) 1985-12-04 1991-06-11 Conrex Pharmaceutical Corporation Transdermal and trans-membrane delivery of drugs
JPS6344532A (ja) 1986-08-11 1988-02-25 Biseibutsu Kagaku Kenkyusho:Kk 豚のレオウイルス感染症ワクチン
US5658779A (en) * 1992-03-20 1997-08-19 Ligochem, Inc. Method of adsorbing viruses from fluid compositions
JPH08214876A (ja) 1995-02-15 1996-08-27 Chemo Sero Therapeut Res Inst ウイルスの調製法
WO1998022588A2 (en) * 1996-11-20 1998-05-28 Introgen Therapeutics, Inc. An improved method for the production and purification of adenoviral vectors
KR20010020308A (ko) 1997-06-24 2001-03-15 스타르크, 카르크 4,4'-디할로겐디페닐설폰을 제조하는 방법
US6136307A (en) 1997-08-13 2000-10-24 Oncolytics Biotech Inc. Reovirus for the treatment of cellular proliferative disorders
US6110461A (en) * 1997-08-13 2000-08-29 Oncolytics Biotech Inc. Reovirus for the treatment of neoplasia
AR028039A1 (es) 2000-05-03 2003-04-23 Oncolytics Biotech Inc Remocion de reovirus de celulas neoplasticas intermediadas por ras a partir de composiciones celulares mixtas
TWI289158B (en) * 2000-08-10 2007-11-01 Oncolytics Biotech Inc Method of producing infectious reovirus

Also Published As

Publication number Publication date
CA2415749C (en) 2009-05-12
DE60111747T2 (de) 2006-04-27
DE60111747D1 (de) 2005-08-04
EP1309672B1 (de) 2005-06-29
PT1586634E (pt) 2008-06-19
WO2002012435A1 (en) 2002-02-14
JP2004505623A (ja) 2004-02-26
BR0113122A (pt) 2003-07-22
US20030166253A1 (en) 2003-09-04
PT1309672E (pt) 2005-09-30
EP1309672A1 (de) 2003-05-14
AU7562801A (en) 2002-02-18
JP2006314336A (ja) 2006-11-24
NZ523510A (en) 2004-08-27
MXPA03000846A (es) 2004-04-05
US20040126869A1 (en) 2004-07-01
IL153847A0 (en) 2003-07-31
DK1586634T3 (da) 2008-08-18
ZA200300410B (en) 2004-01-26
US20060165724A1 (en) 2006-07-27
DK1309672T3 (da) 2005-10-10
AU2001275628B8 (en) 2002-02-18
IL153847A (en) 2007-10-31
US6703232B2 (en) 2004-03-09
EP1586634A1 (de) 2005-10-19
US6528305B2 (en) 2003-03-04
US7049127B2 (en) 2006-05-23
US20020037576A1 (en) 2002-03-28
ATE298788T1 (de) 2005-07-15
TWI289158B (en) 2007-11-01
US7429485B2 (en) 2008-09-30
JP4009532B2 (ja) 2007-11-14
AU2001275628B2 (en) 2007-08-30
DE60133947D1 (de) 2008-06-19
ES2305940T3 (es) 2008-11-01
HK1082765A1 (en) 2006-06-16
AR033993A1 (es) 2004-01-21
EP1586634B1 (de) 2008-05-07
ES2241844T3 (es) 2005-11-01
CA2415749A1 (en) 2002-02-14

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