ATE395431T1 - Parallele verfahren für die genomische analyse - Google Patents

Parallele verfahren für die genomische analyse

Info

Publication number
ATE395431T1
ATE395431T1 AT99955164T AT99955164T ATE395431T1 AT E395431 T1 ATE395431 T1 AT E395431T1 AT 99955164 T AT99955164 T AT 99955164T AT 99955164 T AT99955164 T AT 99955164T AT E395431 T1 ATE395431 T1 AT E395431T1
Authority
AT
Austria
Prior art keywords
parallel methods
genomic analysis
methods
parallel
genomic
Prior art date
Application number
AT99955164T
Other languages
English (en)
Inventor
Michael Strathmann
Original Assignee
Michael Strathmann
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Michael Strathmann filed Critical Michael Strathmann
Application granted granted Critical
Publication of ATE395431T1 publication Critical patent/ATE395431T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1082—Preparation or screening gene libraries by chromosomal integration of polynucleotide sequences, HR-, site-specific-recombination, transposons, viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT99955164T 1998-10-28 1999-10-27 Parallele verfahren für die genomische analyse ATE395431T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10591498P 1998-10-28 1998-10-28
US09/427,834 US6480791B1 (en) 1998-10-28 1999-10-26 Parallel methods for genomic analysis

Publications (1)

Publication Number Publication Date
ATE395431T1 true ATE395431T1 (de) 2008-05-15

Family

ID=26803092

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99955164T ATE395431T1 (de) 1998-10-28 1999-10-27 Parallele verfahren für die genomische analyse

Country Status (8)

Country Link
US (3) US6480791B1 (de)
EP (1) EP1127160B1 (de)
JP (1) JP2003525019A (de)
AT (1) ATE395431T1 (de)
AU (1) AU1133500A (de)
CA (1) CA2348683A1 (de)
DE (1) DE69938735D1 (de)
WO (1) WO2000024937A2 (de)

Families Citing this family (106)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2255599C (en) 1996-04-25 2006-09-05 Bioarray Solutions, Llc Light-controlled electrokinetic assembly of particles near surfaces
US20030009013A1 (en) * 1998-12-30 2003-01-09 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
DE60117556T2 (de) 2000-06-21 2006-11-02 Bioarray Solutions Ltd. Multianalytische molekularanalyse durch verwendung anwendungsspezifischer zufallspartikelarrays
US9709559B2 (en) 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
WO2002006834A2 (en) * 2000-07-19 2002-01-24 Pointilliste, Inc. Nested sorting and high throughput screening
AU2001285155A1 (en) * 2000-08-21 2002-03-04 Lynx Therapeutics, Inc. Polymorphic dna fragments and uses thereof
US7494817B2 (en) * 2000-09-06 2009-02-24 Transnet Yx, Inc. Methods for genotype screening using magnetic particles
US20030082605A1 (en) * 2000-09-06 2003-05-01 Hodge Timothy A. Genomic DNA detection method and system thereof
US20030087286A1 (en) * 2000-09-06 2003-05-08 Hodge Timothy A. Isolation of eukaryotic genomic DNA using magnetically responsive solid functionalized particles
US20050239125A1 (en) * 2000-09-06 2005-10-27 Hodge Timothy A Methods for genotype screening
US20050272085A1 (en) * 2000-09-06 2005-12-08 Hodge Timothy A Methods for forensic and congenic screening
EP1978110B1 (de) * 2000-09-06 2010-05-26 Transnetyx, Inc. Computer-basiertes Verfahren und System zum Screenen von genomischer DNS
US20050266494A1 (en) * 2000-09-06 2005-12-01 Hodge Timothy A System and method for computer network ordering of biological testing
US20030207289A1 (en) * 2001-09-04 2003-11-06 Hodge Timothy A. Detection of genetic sequences using a bipartite probe
FI115139B (fi) * 2001-01-10 2005-03-15 Valtion Teknillinen Menetelmä ja testipakkaus solu- tai kudosnäytteissä olevien polynukleotidien määrässä tapahtuvien vaihteluiden kvantitatiiviseen ja/tai vertailevaan arvioimiseen
US20050260570A1 (en) * 2001-05-29 2005-11-24 Mao Jen-I Sequencing by proxy
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
US20060014186A1 (en) * 2001-09-04 2006-01-19 Hodge Timothy A Methods for genotype screening of a strain disposed on an adsorbent carrier
CA2497740C (en) 2001-10-15 2011-06-21 Bioarray Solutions, Ltd. Multiplexed analysis of polymorphic loci by probe elongation-mediated detection
EP1706826A4 (de) * 2002-01-25 2008-01-30 Applera Corp Verfahren zur aufgabe, annahme und ausführung von bestellungen für produkte und dienstleistungen
US20030190652A1 (en) * 2002-01-25 2003-10-09 De La Vega Francisco M. Methods of validating SNPs and compiling libraries of assays
US20040072195A1 (en) * 2002-01-25 2004-04-15 Hunkapiller Michael W. Single-tube, ready-to-use assay kits, and methods using same
US20090239233A1 (en) * 2002-01-25 2009-09-24 Applera Corporation Single-tube, ready-to-use assay kits, and methods using same
FI20021325A0 (fi) * 2002-07-05 2002-07-05 Valtion Teknillinen Menetelmä ja reagenssipakkaus yksittäisten polynukleotidien määrän määrittämiseksi
AU2003298655A1 (en) 2002-11-15 2004-06-15 Bioarray Solutions, Ltd. Analysis, secure access to, and transmission of array images
TW200412373A (en) * 2003-01-15 2004-07-16 Univ Nat Taiwan RCA combined nanoparticle-based optical detection technique for protein microarray
WO2004104172A2 (en) * 2003-05-15 2004-12-02 Bioarray Solutions, Ltd. Hybridization-mediated analysis of polymorphisms
US20040259118A1 (en) * 2003-06-23 2004-12-23 Macevicz Stephen C. Methods and compositions for nucleic acid sequence analysis
US7927796B2 (en) 2003-09-18 2011-04-19 Bioarray Solutions, Ltd. Number coding for identification of subtypes of coded types of solid phase carriers
CA2539824C (en) 2003-09-22 2015-02-03 Xinwen Wang Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules
CA2544041C (en) 2003-10-28 2015-12-08 Bioarray Solutions Ltd. Optimization of gene expression analysis using immobilized capture probes
CA2544202C (en) 2003-10-29 2012-07-24 Bioarray Solutions Ltd. Multiplexed nucleic acid analysis by fragmentation of double-stranded dna
US7276338B2 (en) * 2003-11-17 2007-10-02 Jacobson Joseph M Nucleotide sequencing via repetitive single molecule hybridization
JP4476050B2 (ja) * 2004-06-30 2010-06-09 株式会社ニデック 視野計
US7848889B2 (en) 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
WO2006035444A2 (en) 2004-09-29 2006-04-06 Tel Hashomer Medical Research Infrastructure And Services Ltd. Composition for improving efficiency of drug delivery
US8486629B2 (en) 2005-06-01 2013-07-16 Bioarray Solutions, Ltd. Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation
DK2302070T3 (da) 2005-06-23 2012-11-26 Keygene Nv Strategier til identifikation og detektion af polymorfismer med højt gennemløb
US10316364B2 (en) 2005-09-29 2019-06-11 Keygene N.V. Method for identifying the source of an amplicon
WO2007037678A2 (en) 2005-09-29 2007-04-05 Keygene N.V. High throughput screening of mutagenized populations
CN103937899B (zh) 2005-12-22 2017-09-08 凯津公司 用于基于aflp的高通量多态性检测的方法
US20070172839A1 (en) * 2006-01-24 2007-07-26 Smith Douglas R Asymmetrical adapters and methods of use thereof
US20070224613A1 (en) * 2006-02-18 2007-09-27 Strathmann Michael P Massively Multiplexed Sequencing
EP3239304B1 (de) * 2006-04-04 2020-08-19 Keygene N.V. Nachweis von molekularmarkern mit hohem durchsatz auf der basis von aflp und mit hoher durchsatzsequenzierung
CN103333949B (zh) 2006-07-12 2015-05-06 凯津公司 使用aflp的高通量物理作图
US20080188001A1 (en) * 2007-02-06 2008-08-07 Michael Paul Strathmann Methods For Gene Targeting
US20080318233A1 (en) * 2007-03-30 2008-12-25 Glenn Travis C Source tagging and normalization of DNA for parallel DNA sequencing, and direct measurement of mutation rates using the same
EP2318527A4 (de) * 2008-07-30 2012-07-04 Michael Strathmann Gen-targeting-verfahren
WO2010056728A1 (en) * 2008-11-11 2010-05-20 Helicos Biosciences Corporation Nucleic acid encoding for multiplex analysis
EP2414548B1 (de) 2009-03-30 2015-10-21 Illumina, Inc. Genexpressionsanalyse in einzelzellen
EP2425011A1 (de) * 2009-04-29 2012-03-07 Hendrix Genetics Research, Technology & Services B.V. Verfahren zum vereinigen von proben zur durchführung eines biologischen tests
US8835358B2 (en) 2009-12-15 2014-09-16 Cellular Research, Inc. Digital counting of individual molecules by stochastic attachment of diverse labels
US9074251B2 (en) * 2011-02-10 2015-07-07 Illumina, Inc. Linking sequence reads using paired code tags
CN103443338B (zh) 2011-02-02 2017-09-22 华盛顿大学商业化中心 大规模平行邻接作图
CA2865575C (en) 2012-02-27 2024-01-16 Cellular Research, Inc. Compositions and kits for molecular counting
WO2014015098A1 (en) 2012-07-18 2014-01-23 Siemens Healthcare Diagnostics Inc. A method of normalizing biological samples
CN111254500B (zh) * 2012-12-10 2024-01-23 分析生物科学有限公司 靶向基因组分析的方法
US9683230B2 (en) 2013-01-09 2017-06-20 Illumina Cambridge Limited Sample preparation on a solid support
DK2970951T3 (da) 2013-03-13 2019-05-13 Illumina Inc Fremgangsmåder til nukleinsyresekventering
KR102758333B1 (ko) 2013-08-28 2025-01-23 벡톤 디킨슨 앤드 컴퍼니 대량의 동시 단일 세포 분석
JP6105076B2 (ja) * 2013-10-21 2017-03-29 株式会社日立製作所 遺伝子解析システム
US10947587B2 (en) 2013-11-05 2021-03-16 The Regents Of The University Of California Single-cell forensic short tandem repeat typing within microfluidic droplets
US20160053301A1 (en) 2014-08-22 2016-02-25 Clearfork Bioscience, Inc. Methods for quantitative genetic analysis of cell free dna
EP3259371B1 (de) 2015-02-19 2020-09-02 Becton, Dickinson and Company Hochdurchsatzeinzelzellenanalyse mit kombination von proteomischen und genomischen informationen
US10988805B2 (en) * 2015-02-20 2021-04-27 The Regents Of The University Of California Methods related to DNA sequencing
WO2016138496A1 (en) 2015-02-27 2016-09-01 Cellular Research, Inc. Spatially addressable molecular barcoding
WO2016160844A2 (en) 2015-03-30 2016-10-06 Cellular Research, Inc. Methods and compositions for combinatorial barcoding
EP4582556A3 (de) 2015-04-23 2025-10-08 Becton, Dickinson and Company Verfahren und zusammensetzungen zur gesamttranskriptomamplifikation
WO2016196229A1 (en) 2015-06-01 2016-12-08 Cellular Research, Inc. Methods for rna quantification
EP3307908B1 (de) 2015-06-09 2019-09-11 Life Technologies Corporation Verfahren zur molekularen markierung
JP6940484B2 (ja) 2015-09-11 2021-09-29 セルラー リサーチ， インコーポレイテッド ライブラリー正規化のための方法および組成物
JP6913089B2 (ja) 2015-11-11 2021-08-04 レゾリューション バイオサイエンス， インコーポレイテッド Ｄｎａライブラリーの高効率構築
JP7129343B2 (ja) 2016-05-02 2022-09-01 ベクトン・ディキンソン・アンド・カンパニー 正確な分子バーコーディング
US10301677B2 (en) 2016-05-25 2019-05-28 Cellular Research, Inc. Normalization of nucleic acid libraries
ES2979395T3 (es) 2016-05-26 2024-09-25 Becton Dickinson Co Métodos de ajuste del recuento de etiquetas moleculares
US10202641B2 (en) 2016-05-31 2019-02-12 Cellular Research, Inc. Error correction in amplification of samples
US10640763B2 (en) 2016-05-31 2020-05-05 Cellular Research, Inc. Molecular indexing of internal sequences
US11319594B2 (en) 2016-08-25 2022-05-03 Resolution Bioscience, Inc. Methods for the detection of genomic copy changes in DNA samples
CN109791157B (zh) 2016-09-26 2022-06-07 贝克顿迪金森公司 使用具有条形码化的寡核苷酸序列的试剂测量蛋白质表达
ES2961580T3 (es) 2017-01-13 2024-03-12 Cellular Res Inc Revestimiento hidrófilo de canales de fluidos
CN110382708A (zh) 2017-02-01 2019-10-25 赛卢拉研究公司 使用阻断性寡核苷酸进行选择性扩增
CN110719959B (zh) 2017-06-05 2021-08-06 贝克顿迪金森公司 针对单细胞的样品索引
EP3728636B1 (de) 2017-12-19 2024-09-11 Becton, Dickinson and Company Mit oligonukleotiden assoziierte teilchen
CN112272710A (zh) 2018-05-03 2021-01-26 贝克顿迪金森公司 高通量多组学样品分析
JP7358388B2 (ja) 2018-05-03 2023-10-10 ベクトン・ディキンソン・アンド・カンパニー 反対側の転写物末端における分子バーコーディング
ES2992135T3 (es) 2018-10-01 2024-12-09 Becton Dickinson Co Determinar secuencias de transcripción 5’
US11932849B2 (en) 2018-11-08 2024-03-19 Becton, Dickinson And Company Whole transcriptome analysis of single cells using random priming
US11492660B2 (en) 2018-12-13 2022-11-08 Becton, Dickinson And Company Selective extension in single cell whole transcriptome analysis
US11371076B2 (en) 2019-01-16 2022-06-28 Becton, Dickinson And Company Polymerase chain reaction normalization through primer titration
ES2945227T3 (es) 2019-01-23 2023-06-29 Becton Dickinson Co Oligonucleótidos asociados con anticuerpos
WO2020167920A1 (en) 2019-02-14 2020-08-20 Cellular Research, Inc. Hybrid targeted and whole transcriptome amplification
US11965208B2 (en) 2019-04-19 2024-04-23 Becton, Dickinson And Company Methods of associating phenotypical data and single cell sequencing data
CN120099137A (zh) 2019-07-22 2025-06-06 贝克顿迪金森公司 单细胞染色质免疫沉淀测序测定
JP7522189B2 (ja) 2019-11-08 2024-07-24 ベクトン・ディキンソン・アンド・カンパニー 免疫レパートリーシーケンシングのための完全長ｖ（ｄ）ｊ情報を得るためのランダムプライミングの使用
WO2021146219A1 (en) 2020-01-13 2021-07-22 Becton, Dickinson And Company Cell capture using du-containing oligonucleotides
US11649497B2 (en) 2020-01-13 2023-05-16 Becton, Dickinson And Company Methods and compositions for quantitation of proteins and RNA
WO2021155057A1 (en) 2020-01-29 2021-08-05 Becton, Dickinson And Company Barcoded wells for spatial mapping of single cells through sequencing
WO2021173719A1 (en) 2020-02-25 2021-09-02 Becton, Dickinson And Company Bi-specific probes to enable the use of single-cell samples as single color compensation control
US11661625B2 (en) 2020-05-14 2023-05-30 Becton, Dickinson And Company Primers for immune repertoire profiling
US12157913B2 (en) 2020-06-02 2024-12-03 Becton, Dickinson And Company Oligonucleotides and beads for 5 prime gene expression assay
US11932901B2 (en) 2020-07-13 2024-03-19 Becton, Dickinson And Company Target enrichment using nucleic acid probes for scRNAseq
US12391940B2 (en) 2020-07-31 2025-08-19 Becton, Dickinson And Company Single cell assay for transposase-accessible chromatin
EP4247967A1 (de) 2020-11-20 2023-09-27 Becton, Dickinson and Company Profilierung von stark exprimierten und schwach exprimierten proteinen
CN116685850A (zh) 2020-12-15 2023-09-01 贝克顿迪金森公司 单细胞分泌组分析
US12176070B2 (en) * 2021-04-19 2024-12-24 University Of Utah Research Foundation Systems and methods for facilitating rapid genome sequence analysis
CN114649055B (zh) * 2022-04-15 2022-10-21 北京贝瑞和康生物技术有限公司 用于检测单核苷酸变异和插入缺失的方法、设备和介质

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4942124A (en) 1987-08-11 1990-07-17 President And Fellows Of Harvard College Multiplex sequencing
US5149625A (en) * 1987-08-11 1992-09-22 President And Fellows Of Harvard College Multiplex analysis of DNA
US5641658A (en) * 1994-08-03 1997-06-24 Mosaic Technologies, Inc. Method for performing amplification of nucleic acid with two primers bound to a single solid support
JP3612092B2 (ja) 1994-09-07 2005-01-19 株式会社日立製作所 Ｄｎａの分離・分取法及びその解析法
US5604097A (en) * 1994-10-13 1997-02-18 Spectragen, Inc. Methods for sorting polynucleotides using oligonucleotide tags
WO1996036737A1 (en) 1995-05-19 1996-11-21 Ely Michael Rabani Parallel multiplex polynucleotide sequencing
US5780231A (en) 1995-11-17 1998-07-14 Lynx Therapeutics, Inc. DNA extension and analysis with rolling primers
US5854033A (en) * 1995-11-21 1998-12-29 Yale University Rolling circle replication reporter systems
DE69701671T3 (de) 1996-01-23 2006-08-17 Qiagen Genomics, Inc., Bothell Verfahren und zusammenstellungen zur sequenzbestimmung von nukleinsäuremolekülen
PL331513A1 (en) * 1996-06-06 1999-07-19 Lynx Therapeutics Method of sequencing, by a ligand effect, specific encoded adapters and composition containing double-string oligonucleotidic adapters
US5866336A (en) * 1996-07-16 1999-02-02 Oncor, Inc. Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
US5935793A (en) 1996-09-27 1999-08-10 The Chinese University Of Hong Kong Parallel polynucleotide sequencing method using tagged primers
US6117634A (en) * 1997-03-05 2000-09-12 The Reagents Of The University Of Michigan Nucleic acid sequencing and mapping
US6312904B1 (en) 1997-07-11 2001-11-06 Xzillion Gmbh & Co. Kg Characterizing nucleic acid
US6013486A (en) 1997-09-17 2000-01-11 Yale University Method for selection of insertion mutants

Also Published As

Publication number Publication date
JP2003525019A (ja) 2003-08-26
EP1127160B1 (de) 2008-05-14
US6480791B1 (en) 2002-11-12
DE69938735D1 (de) 2008-06-26
CA2348683A1 (en) 2000-05-04
US20130252829A1 (en) 2013-09-26
EP1127160A2 (de) 2001-08-29
WO2000024937A2 (en) 2000-05-04
US20080214403A1 (en) 2008-09-04
WO2000024937A3 (en) 2000-08-10
AU1133500A (en) 2000-05-15

Similar Documents

Publication Publication Date Title
ATE395431T1 (de) Parallele verfahren für die genomische analyse
EP1030912A4 (de) Vorrichtung für die zellyse
DE69824586D1 (de) Probenträger hoher dichte für die analyse biologischer proben
DE60044964D1 (de) Elektrolyt für elektrochemische Vorrichtung
ATE263377T1 (de) Vorrichtung für klinische analysen
BR9607193B1 (pt) teste de eletroquimioluscÊncia multi-especÍfico de méltiplos conjuntos.
ATE409236T1 (de) Derivatisierte nukleinsäuren und deren verwendung
ATE244771T1 (de) Verfahren zur erkennung von nukleinsäuremethylierungen durch aflp
ATE350488T1 (de) Verfahren und testsysteme zur identifizierung von elite event gat-zm1 in biologischen proben
DE69822331D1 (de) Vieladriges mikrokabel insbesondere für gefässverschliessende vorrichtung zur behandlung von aneurismen
DE59909825D1 (de) Vorrichtung zur visualisierung von molekülen
DE69902769D1 (de) Elektrochemisches verfahren
DE69823008D1 (de) Verarbeitungshilfsmittel für schmelzverarbeitbare polymere
ATE336591T1 (de) Nachweisverfahren für kurze sequenzvarianten
GB9704054D0 (en) Assay
DE69914316T2 (de) Stanzvorrichtung für stahlständer
DE69816661D1 (de) Vorrichtung für elektrophorese
DE60036883D1 (de) Verfahren für die Zuteilung von Kanälen zu Funkgeräten, und Vorrichtung dafür
DE59904723D1 (de) Vorrichtung zur katalytischen umsetzung von wasserstoff
DE69904497D1 (de) Entnahmegerät für bodenproben
DE59910207D1 (de) Datenbus für mehrere teilnehmer
DE59910206D1 (de) Datenbus für mehrere teilnehmer
DE69917310D1 (de) Vorrichtung für ein öffnungsfähiges dach
DE59904500D1 (de) Verfahren und anordnung zur vorhersage von messdaten anhand vorgegebener messdaten
DE59912094D1 (de) Datenbus für mehrere teilnehmer

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties