ATE396278T1 - Verfahren zur herstellung eines sensors - Google Patents
Verfahren zur herstellung eines sensorsInfo
- Publication number
- ATE396278T1 ATE396278T1 AT02763782T AT02763782T ATE396278T1 AT E396278 T1 ATE396278 T1 AT E396278T1 AT 02763782 T AT02763782 T AT 02763782T AT 02763782 T AT02763782 T AT 02763782T AT E396278 T1 ATE396278 T1 AT E396278T1
- Authority
- AT
- Austria
- Prior art keywords
- protein
- producing
- sensor
- protein matrix
- immobilizing
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 abstract 6
- 108090000623 proteins and genes Proteins 0.000 abstract 6
- 239000011159 matrix material Substances 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 238000004132 cross linking Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000003100 immobilizing effect Effects 0.000 abstract 1
- 238000002386 leaching Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000008961 swelling Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/54—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/817—Enzyme or microbe electrode
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Emergency Medicine (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Pressure Sensors (AREA)
- Measuring Fluid Pressure (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33566301P | 2001-10-23 | 2001-10-23 | |
| US10/033,723 US7192766B2 (en) | 2001-10-23 | 2001-12-27 | Sensor containing molded solidified protein |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE396278T1 true ATE396278T1 (de) | 2008-06-15 |
Family
ID=26710060
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02763782T ATE396278T1 (de) | 2001-10-23 | 2002-09-27 | Verfahren zur herstellung eines sensors |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US7192766B2 (de) |
| EP (1) | EP1437937B1 (de) |
| JP (1) | JP2005507007A (de) |
| AT (1) | ATE396278T1 (de) |
| AU (1) | AU2002327774A1 (de) |
| CA (1) | CA2457545A1 (de) |
| DE (1) | DE60226759D1 (de) |
| WO (1) | WO2003035891A2 (de) |
Families Citing this family (74)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6535753B1 (en) | 1998-08-20 | 2003-03-18 | Microsense International, Llc | Micro-invasive method for painless detection of analytes in extra-cellular space |
| US6338790B1 (en) | 1998-10-08 | 2002-01-15 | Therasense, Inc. | Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator |
| US8226814B2 (en) * | 2001-05-11 | 2012-07-24 | Abbott Diabetes Care Inc. | Transition metal complexes with pyridyl-imidazole ligands |
| US6676816B2 (en) | 2001-05-11 | 2004-01-13 | Therasense, Inc. | Transition metal complexes with (pyridyl)imidazole ligands and sensors using said complexes |
| US8070934B2 (en) | 2001-05-11 | 2011-12-06 | Abbott Diabetes Care Inc. | Transition metal complexes with (pyridyl)imidazole ligands |
| US6932894B2 (en) * | 2001-05-15 | 2005-08-23 | Therasense, Inc. | Biosensor membranes composed of polymers containing heterocyclic nitrogens |
| US7052591B2 (en) | 2001-09-21 | 2006-05-30 | Therasense, Inc. | Electrodeposition of redox polymers and co-electrodeposition of enzymes by coordinative crosslinking |
| US7192766B2 (en) * | 2001-10-23 | 2007-03-20 | Medtronic Minimed, Inc. | Sensor containing molded solidified protein |
| US7299082B2 (en) | 2003-10-31 | 2007-11-20 | Abbott Diabetes Care, Inc. | Method of calibrating an analyte-measurement device, and associated methods, devices and systems |
| US7699964B2 (en) | 2004-02-09 | 2010-04-20 | Abbott Diabetes Care Inc. | Membrane suitable for use in an analyte sensor, analyte sensor, and associated method |
| US8165651B2 (en) | 2004-02-09 | 2012-04-24 | Abbott Diabetes Care Inc. | Analyte sensor, and associated system and method employing a catalytic agent |
| US7545272B2 (en) | 2005-02-08 | 2009-06-09 | Therasense, Inc. | RF tag on test strips, test strip vials and boxes |
| US7885698B2 (en) | 2006-02-28 | 2011-02-08 | Abbott Diabetes Care Inc. | Method and system for providing continuous calibration of implantable analyte sensors |
| US20120046533A1 (en) | 2007-08-29 | 2012-02-23 | Medtronic Minimed, Inc. | Combined sensor and infusion sets |
| US9968742B2 (en) | 2007-08-29 | 2018-05-15 | Medtronic Minimed, Inc. | Combined sensor and infusion set using separated sites |
| US11730407B2 (en) | 2008-03-28 | 2023-08-22 | Dexcom, Inc. | Polymer membranes for continuous analyte sensors |
| US8583204B2 (en) | 2008-03-28 | 2013-11-12 | Dexcom, Inc. | Polymer membranes for continuous analyte sensors |
| US8858501B2 (en) * | 2008-04-11 | 2014-10-14 | Medtronic Minimed, Inc. | Reservoir barrier layer systems and methods |
| US8206353B2 (en) * | 2008-04-11 | 2012-06-26 | Medtronic Minimed, Inc. | Reservoir barrier layer systems and methods |
| US9295776B2 (en) * | 2008-04-11 | 2016-03-29 | Medtronic Minimed, Inc. | Reservoir plunger head systems and methods |
| AU2009295960A1 (en) | 2008-09-29 | 2010-04-01 | Cardiaq Valve Technologies, Inc. | Heart valve |
| EP2341871B1 (de) | 2008-10-01 | 2017-03-22 | Edwards Lifesciences CardiAQ LLC | Abgabesystem für ein gefässimplantat |
| US8394463B1 (en) | 2009-01-23 | 2013-03-12 | Medtronic Minimed, Inc. | Crosslinking compounds at negative pressures and materials made by such methods |
| EP4119098A1 (de) | 2009-04-15 | 2023-01-18 | Edwards Lifesciences CardiAQ LLC | Gefässimplantat und freisetzungssystem |
| US20110082356A1 (en) | 2009-10-01 | 2011-04-07 | Medtronic Minimed, Inc. | Analyte sensor apparatuses having interference rejection membranes and methods for making and using them |
| US20110288388A1 (en) | 2009-11-20 | 2011-11-24 | Medtronic Minimed, Inc. | Multi-conductor lead configurations useful with medical device systems and methods for making and using them |
| US8507256B2 (en) * | 2009-11-24 | 2013-08-13 | Foster-Miller, Inc. | Sorption reinforced catalytic coating system and method for the degradation of threat agents |
| US8660628B2 (en) | 2009-12-21 | 2014-02-25 | Medtronic Minimed, Inc. | Analyte sensors comprising blended membrane compositions and methods for making and using them |
| US10448872B2 (en) | 2010-03-16 | 2019-10-22 | Medtronic Minimed, Inc. | Analyte sensor apparatuses having improved electrode configurations and methods for making and using them |
| US8579964B2 (en) | 2010-05-05 | 2013-11-12 | Neovasc Inc. | Transcatheter mitral valve prosthesis |
| US9215995B2 (en) | 2010-06-23 | 2015-12-22 | Medtronic Minimed, Inc. | Sensor systems having multiple probes and electrode arrays |
| US9308087B2 (en) | 2011-04-28 | 2016-04-12 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
| US9554897B2 (en) | 2011-04-28 | 2017-01-31 | Neovasc Tiara Inc. | Methods and apparatus for engaging a valve prosthesis with tissue |
| US9008744B2 (en) | 2011-05-06 | 2015-04-14 | Medtronic Minimed, Inc. | Method and apparatus for continuous analyte monitoring |
| US9493807B2 (en) | 2012-05-25 | 2016-11-15 | Medtronic Minimed, Inc. | Foldover sensors and methods for making and using them |
| US9345573B2 (en) | 2012-05-30 | 2016-05-24 | Neovasc Tiara Inc. | Methods and apparatus for loading a prosthesis onto a delivery system |
| US20140012115A1 (en) | 2012-07-03 | 2014-01-09 | Medtronic Minimed, Inc. | Plasma deposited adhesion promoter layers for use with analyte sensors |
| US10194840B2 (en) | 2012-12-06 | 2019-02-05 | Medtronic Minimed, Inc. | Microarray electrodes useful with analyte sensors and methods for making and using them |
| US10426383B2 (en) | 2013-01-22 | 2019-10-01 | Medtronic Minimed, Inc. | Muting glucose sensor oxygen response and reducing electrode edge growth with pulsed current plating |
| US10583002B2 (en) | 2013-03-11 | 2020-03-10 | Neovasc Tiara Inc. | Prosthetic valve with anti-pivoting mechanism |
| US9681951B2 (en) | 2013-03-14 | 2017-06-20 | Edwards Lifesciences Cardiaq Llc | Prosthesis with outer skirt and anchors |
| US9572665B2 (en) | 2013-04-04 | 2017-02-21 | Neovasc Tiara Inc. | Methods and apparatus for delivering a prosthetic valve to a beating heart |
| US20150122647A1 (en) | 2013-11-07 | 2015-05-07 | Medtronic Minimed, Inc. | Enzyme matrices for use with ethylene oxide sterilization |
| AU2014374361B9 (en) | 2013-12-31 | 2019-07-04 | Abbott Diabetes Care Inc. | Self-powered analyte sensor and devices using the same |
| US10245034B2 (en) * | 2015-08-31 | 2019-04-02 | Ethicon Llc | Inducing tissue adhesions using surgical adjuncts and medicants |
| US10569071B2 (en) | 2015-08-31 | 2020-02-25 | Ethicon Llc | Medicant eluting adjuncts and methods of using medicant eluting adjuncts |
| US10324058B2 (en) | 2016-04-28 | 2019-06-18 | Medtronic Minimed, Inc. | In-situ chemistry stack for continuous glucose sensors |
| WO2017195035A1 (en) | 2016-05-10 | 2017-11-16 | Interface Biologics, Inc. | Implantable glucose sensors having a biostable surface |
| US11298059B2 (en) | 2016-05-13 | 2022-04-12 | PercuSense, Inc. | Analyte sensor |
| US11179078B2 (en) | 2016-06-06 | 2021-11-23 | Medtronic Minimed, Inc. | Polycarbonate urea/urethane polymers for use with analyte sensors |
| JP2020501157A (ja) | 2016-12-09 | 2020-01-16 | ノースイースタン ユニバーシティ | 耐久性のある酵素ベースのバイオセンサーおよび滴下堆積固定化のための方法 |
| US11134868B2 (en) | 2017-03-17 | 2021-10-05 | Medtronic Minimed, Inc. | Metal pillar device structures and methods for making and using them in electrochemical and/or electrocatalytic applications |
| US10856784B2 (en) | 2017-06-30 | 2020-12-08 | Medtronic Minimed, Inc. | Sensor initialization methods for faster body sensor response |
| US12042284B2 (en) | 2018-01-23 | 2024-07-23 | Medtronic Minimed, Inc. | Implantable polymer surfaces exhibiting reduced in vivo inflammatory responses |
| US11186859B2 (en) | 2018-02-07 | 2021-11-30 | Medtronic Minimed, Inc. | Multilayer electrochemical analyte sensors and methods for making and using them |
| US11220735B2 (en) | 2018-02-08 | 2022-01-11 | Medtronic Minimed, Inc. | Methods for controlling physical vapor deposition metal film adhesion to substrates and surfaces |
| US11583213B2 (en) | 2018-02-08 | 2023-02-21 | Medtronic Minimed, Inc. | Glucose sensor electrode design |
| EP3794135A1 (de) | 2018-05-16 | 2021-03-24 | Medtronic MiniMed, Inc. | Thermisch stabile glukosebegrenzende membran für glukosesensoren |
| US11718865B2 (en) | 2019-07-26 | 2023-08-08 | Medtronic Minimed, Inc. | Methods to improve oxygen delivery to implantable sensors |
| US11523757B2 (en) | 2019-08-01 | 2022-12-13 | Medtronic Minimed, Inc. | Micro-pillar working electrodes design to reduce backflow of hydrogen peroxide in glucose sensor |
| US12082924B2 (en) | 2020-07-31 | 2024-09-10 | Medtronic Minimed, Inc. | Sensor identification and integrity check design |
| EP4225141A4 (de) * | 2020-10-06 | 2024-10-23 | Allez Health Inc. | Arbeitsdraht für einen kontinuierlichen biologischen sensor mit einem enzymimmobilisierungsnetzwerk |
| US20220133190A1 (en) | 2020-10-29 | 2022-05-05 | Medtronic Minimed, Inc. | Glucose biosensors comprising direct electron transfer enzymes and methods of making and using them |
| US11998330B2 (en) | 2021-01-29 | 2024-06-04 | Medtronic Minimed, Inc. | Interference rejection membranes useful with analyte sensors |
| US20220338768A1 (en) | 2021-04-09 | 2022-10-27 | Medtronic Minimed, Inc. | Hexamethyldisiloxane membranes for analyte sensors |
| US12433515B2 (en) | 2021-08-13 | 2025-10-07 | Medtronic Minimed, Inc. | Dry electrochemical impedance spectroscopy metrology for conductive chemical layers |
| US12201421B2 (en) | 2021-10-08 | 2025-01-21 | Medtronic Minimed, Inc. | Immunosuppressant releasing coatings |
| US12442786B2 (en) | 2021-10-14 | 2025-10-14 | Medtronic Minimed, Inc. | Sensors for 3-hydroxybutyrate detection |
| US12527500B2 (en) | 2021-12-02 | 2026-01-20 | Medtronic Minimed, Inc. | Ketone limiting membrane and dual layer membrane approach for ketone sensing |
| US20240023849A1 (en) | 2022-07-20 | 2024-01-25 | Medtronic Minimed, Inc. | Acrylate hydrogel membrane for dual function of diffusion limiting membrane as well as attenuation to the foreign body response |
| EP4382611A1 (de) | 2022-08-31 | 2024-06-12 | Medtronic MiniMed, Inc. | Sensoren zur 3-hydroxybutyrat-detektion |
| US12522853B2 (en) | 2022-10-28 | 2026-01-13 | Medtronic Minimed, Inc. | Enzyme mediator functionalized polymers for use with analyte sensors |
| US20240335147A1 (en) | 2023-04-05 | 2024-10-10 | Medtronic Minimed, Inc. | Analyte transporting membranes for use with analyte sensors |
| US20250281074A1 (en) | 2024-03-07 | 2025-09-11 | Medtronic Minimed, Inc. | Sensor membranes for dexamethosone rejection |
Family Cites Families (82)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US426638A (en) * | 1890-04-29 | Belt rest | ||
| US424696A (en) * | 1890-04-01 | Fan-blower | ||
| CH564031A5 (de) * | 1968-03-29 | 1975-07-15 | Anvar | |
| US4240438A (en) | 1978-10-02 | 1980-12-23 | Wisconsin Alumni Research Foundation | Method for monitoring blood glucose levels and elements |
| US4486408A (en) | 1981-04-07 | 1984-12-04 | Kiel Johnathan L | Insoluble crosslinked cytotoxic oxidase-peroxidase system |
| US4478946A (en) | 1981-07-02 | 1984-10-23 | South African Inventions Development Corporation | Carrier bound immunosorbent |
| US4568335A (en) | 1981-08-28 | 1986-02-04 | Markwell Medical Institute, Inc. | Device for the controlled infusion of medications |
| US4771772A (en) | 1982-08-09 | 1988-09-20 | Medtronic, Inc. | Robotic implantable medical device and/or component restoration system |
| US4628928A (en) | 1982-08-09 | 1986-12-16 | Medtronic, Inc. | Robotic implantable medical device and/or component restoration system |
| US4479796A (en) | 1982-11-15 | 1984-10-30 | Medtronic, Inc. | Self-regenerating drug administration device |
| US4650547A (en) | 1983-05-19 | 1987-03-17 | The Regents Of The University Of California | Method and membrane applicable to implantable sensor |
| US4484987A (en) | 1983-05-19 | 1984-11-27 | The Regents Of The University Of California | Method and membrane applicable to implantable sensor |
| JPS60260611A (ja) | 1984-06-08 | 1985-12-23 | Mitsubishi Petrochem Co Ltd | 高分子量クレゾ−ルノボラツク樹脂の製造方法 |
| US4890620A (en) | 1985-09-20 | 1990-01-02 | The Regents Of The University Of California | Two-dimensional diffusion glucose substrate sensing electrode |
| US4994167A (en) | 1986-04-15 | 1991-02-19 | Markwell Medical Institute, Inc. | Biological fluid measuring device |
| US4757022A (en) | 1986-04-15 | 1988-07-12 | Markwell Medical Institute, Inc. | Biological fluid measuring device |
| US4703756A (en) | 1986-05-06 | 1987-11-03 | The Regents Of The University Of California | Complete glucose monitoring system with an implantable, telemetered sensor module |
| US4891104A (en) * | 1987-04-24 | 1990-01-02 | Smithkline Diagnostics, Inc. | Enzymatic electrode and electrode module and method of use |
| FR2617763B1 (fr) * | 1987-07-07 | 1989-12-01 | Essilor Int | Procede de fabrication de lentille de contact en un polymere proteique naturel, par moulage avant reticulation |
| JP2672561B2 (ja) * | 1988-01-29 | 1997-11-05 | テルモ株式会社 | 膜被履センサ |
| US5266688A (en) | 1988-06-21 | 1993-11-30 | Chiron Corporation | Polynucleotide sequence for production of glucose oxidase in recombinant systems |
| US5094951A (en) | 1988-06-21 | 1992-03-10 | Chiron Corporation | Production of glucose oxidase in recombinant systems |
| US4911168A (en) | 1989-01-13 | 1990-03-27 | Pacesetter Infusion, Ltd. | Method of screening and selecting intraperitoneal medication infusion pump candidates |
| US5270446A (en) | 1989-04-04 | 1993-12-14 | Suntory Limited | Decolorized crosslinked products and method for decolorization of crosslinked products |
| US5431160A (en) * | 1989-07-19 | 1995-07-11 | University Of New Mexico | Miniature implantable refillable glucose sensor and material therefor |
| US5985129A (en) | 1989-12-14 | 1999-11-16 | The Regents Of The University Of California | Method for increasing the service life of an implantable sensor |
| US5593852A (en) | 1993-12-02 | 1997-01-14 | Heller; Adam | Subcutaneous glucose electrode |
| US5773270A (en) | 1991-03-12 | 1998-06-30 | Chiron Diagnostics Corporation | Three-layered membrane for use in an electrochemical sensor system |
| US5328460A (en) | 1991-06-21 | 1994-07-12 | Pacesetter Infusion, Ltd. | Implantable medication infusion pump including self-contained acoustic fault detection apparatus |
| GB9311784D0 (en) | 1993-06-08 | 1993-07-28 | Univ Alberta | Vascular bioartificial organ |
| US5791344A (en) | 1993-11-19 | 1998-08-11 | Alfred E. Mann Foundation For Scientific Research | Patient monitoring system |
| US5497772A (en) | 1993-11-19 | 1996-03-12 | Alfred E. Mann Foundation For Scientific Research | Glucose monitoring system |
| US5494562A (en) | 1994-06-27 | 1996-02-27 | Ciba Corning Diagnostics Corp. | Electrochemical sensors |
| US5667983A (en) | 1994-10-24 | 1997-09-16 | Chiron Diagnostics Corporation | Reagents with enhanced performance in clinical diagnostic systems |
| US5741319A (en) | 1995-01-27 | 1998-04-21 | Medtronic, Inc. | Biocompatible medical lead |
| US5995860A (en) | 1995-07-06 | 1999-11-30 | Thomas Jefferson University | Implantable sensor and system for measurement and control of blood constituent levels |
| US6267958B1 (en) | 1995-07-27 | 2001-07-31 | Genentech, Inc. | Protein formulation |
| US5741211A (en) | 1995-10-26 | 1998-04-21 | Medtronic, Inc. | System and method for continuous monitoring of diabetes-related blood constituents |
| US6002954A (en) | 1995-11-22 | 1999-12-14 | The Regents Of The University Of California | Detection of biological molecules using boronate-based chemical amplification and optical sensors |
| ATE278801T1 (de) | 1995-11-22 | 2004-10-15 | Medtronic Minimed Inc | Detektion von biologischen molekülen unter verwendung von chemischer amplifikation und optischem sensor |
| SE9504233D0 (sv) | 1995-11-27 | 1995-11-27 | Pacesetter Ab | Implantable medical device |
| US5834232A (en) * | 1996-05-01 | 1998-11-10 | Zymogenetics, Inc. | Cross-linked gelatin gels and methods of making them |
| JP2000515778A (ja) | 1996-07-08 | 2000-11-28 | アニマス コーポレーシヨン | 体液成分レベルの生体内測定および制御のための埋込可能センサーおよびシステム |
| JP2943700B2 (ja) | 1996-07-10 | 1999-08-30 | 日本電気株式会社 | バイオセンサ |
| US5707502A (en) | 1996-07-12 | 1998-01-13 | Chiron Diagnostics Corporation | Sensors for measuring analyte concentrations and methods of making same |
| US5696314A (en) | 1996-07-12 | 1997-12-09 | Chiron Diagnostics Corporation | Multilayer enzyme electrode membranes and methods of making same |
| US5804048A (en) | 1996-08-15 | 1998-09-08 | Via Medical Corporation | Electrode assembly for assaying glucose |
| US5932175A (en) | 1996-09-25 | 1999-08-03 | Via Medical Corporation | Sensor apparatus for use in measuring a parameter of a fluid sample |
| EP0944731B1 (de) | 1996-11-14 | 2006-01-18 | Radiometer Medical ApS | Enzymsensor |
| US5964993A (en) * | 1996-12-19 | 1999-10-12 | Implanted Biosystems Inc. | Glucose sensor |
| DE69809391T2 (de) | 1997-02-06 | 2003-07-10 | Therasense, Inc. | Kleinvolumiger sensor zur in-vitro bestimmung |
| US6001067A (en) | 1997-03-04 | 1999-12-14 | Shults; Mark C. | Device and method for determining analyte levels |
| US6171586B1 (en) | 1997-06-13 | 2001-01-09 | Genentech, Inc. | Antibody formulation |
| US5919216A (en) | 1997-06-16 | 1999-07-06 | Medtronic, Inc. | System and method for enhancement of glucose production by stimulation of pancreatic beta cells |
| US6093167A (en) | 1997-06-16 | 2000-07-25 | Medtronic, Inc. | System for pancreatic stimulation and glucose measurement |
| US6125290A (en) | 1998-10-30 | 2000-09-26 | Medtronic, Inc. | Tissue overgrowth detector for implantable medical device |
| US6125291A (en) | 1998-10-30 | 2000-09-26 | Medtronic, Inc. | Light barrier for medical electrical lead oxygen sensor |
| US6198952B1 (en) | 1998-10-30 | 2001-03-06 | Medtronic, Inc. | Multiple lens oxygen sensor for medical electrical lead |
| US6248080B1 (en) | 1997-09-03 | 2001-06-19 | Medtronic, Inc. | Intracranial monitoring and therapy delivery control device, system and method |
| US6134459A (en) | 1998-10-30 | 2000-10-17 | Medtronic, Inc. | Light focusing apparatus for medical electrical lead oxygen sensor |
| US6144866A (en) | 1998-10-30 | 2000-11-07 | Medtronic, Inc. | Multiple sensor assembly for medical electric lead |
| US6259937B1 (en) * | 1997-09-12 | 2001-07-10 | Alfred E. Mann Foundation | Implantable substrate sensor |
| US6268161B1 (en) | 1997-09-30 | 2001-07-31 | M-Biotech, Inc. | Biosensor |
| US5941906A (en) | 1997-10-15 | 1999-08-24 | Medtronic, Inc. | Implantable, modular tissue stimulator |
| US6027479A (en) | 1998-02-27 | 2000-02-22 | Via Medical Corporation | Medical apparatus incorporating pressurized supply of storage liquid |
| US6103033A (en) | 1998-03-04 | 2000-08-15 | Therasense, Inc. | Process for producing an electrochemical biosensor |
| US5992211A (en) | 1998-04-23 | 1999-11-30 | Medtronic, Inc. | Calibrated medical sensing catheter system |
| US6175752B1 (en) | 1998-04-30 | 2001-01-16 | Therasense, Inc. | Analyte monitoring device and methods of use |
| US5934232A (en) | 1998-06-12 | 1999-08-10 | General Motors Corporation | Engine valve lift mechanism |
| JP2002518135A (ja) | 1998-06-23 | 2002-06-25 | サージカル シーランツ， インコーポレイテッド | 生体接着性の外科用シーラントおよび移植可能デバイスのためのカルボジイミド架橋アルブミン |
| US6280587B1 (en) | 1998-07-02 | 2001-08-28 | Nec Corporation | Enzyme electrode and a biosensor and a measuring apparatus therewith |
| US6251260B1 (en) | 1998-08-24 | 2001-06-26 | Therasense, Inc. | Potentiometric sensors for analytic determination |
| US6159240A (en) | 1998-08-31 | 2000-12-12 | Medtronic, Inc. | Rigid annuloplasty device that becomes compliant after implantation |
| US6201980B1 (en) | 1998-10-05 | 2001-03-13 | The Regents Of The University Of California | Implantable medical sensor system |
| US6163723A (en) | 1998-10-22 | 2000-12-19 | Medtronic, Inc. | Circuit and method for implantable dual sensor medical electrical lead |
| US6261280B1 (en) | 1999-03-22 | 2001-07-17 | Medtronic, Inc | Method of obtaining a measure of blood glucose |
| USD424696S (en) | 1999-05-06 | 2000-05-09 | Therasense, Inc. | Glucose sensor |
| USD426638S (en) | 1999-05-06 | 2000-06-13 | Therasense, Inc. | Glucose sensor buttons |
| US6368274B1 (en) | 1999-07-01 | 2002-04-09 | Medtronic Minimed, Inc. | Reusable analyte sensor site and method of using the same |
| US6343225B1 (en) * | 1999-09-14 | 2002-01-29 | Implanted Biosystems, Inc. | Implantable glucose sensor |
| AU2001279134A1 (en) | 2000-07-31 | 2002-02-13 | Maxygen, Inc. | Nucleotide incorporating enzymes |
| US7192766B2 (en) * | 2001-10-23 | 2007-03-20 | Medtronic Minimed, Inc. | Sensor containing molded solidified protein |
-
2001
- 2001-12-27 US US10/033,723 patent/US7192766B2/en not_active Expired - Lifetime
-
2002
- 2002-09-27 WO PCT/US2002/030942 patent/WO2003035891A2/en not_active Ceased
- 2002-09-27 AU AU2002327774A patent/AU2002327774A1/en not_active Abandoned
- 2002-09-27 EP EP02763782A patent/EP1437937B1/de not_active Expired - Lifetime
- 2002-09-27 AT AT02763782T patent/ATE396278T1/de not_active IP Right Cessation
- 2002-09-27 DE DE60226759T patent/DE60226759D1/de not_active Expired - Lifetime
- 2002-09-27 CA CA002457545A patent/CA2457545A1/en not_active Abandoned
- 2002-09-27 JP JP2003538391A patent/JP2005507007A/ja active Pending
-
2004
- 2004-08-03 US US10/911,172 patent/US7435569B2/en not_active Expired - Lifetime
-
2005
- 2005-05-04 US US11/122,172 patent/US8137927B2/en not_active Expired - Fee Related
-
2008
- 2008-07-24 US US12/179,502 patent/US8187851B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2005507007A (ja) | 2005-03-10 |
| US20090081753A1 (en) | 2009-03-26 |
| DE60226759D1 (de) | 2008-07-03 |
| WO2003035891A3 (en) | 2003-11-20 |
| US7435569B2 (en) | 2008-10-14 |
| AU2002327774A1 (en) | 2003-05-06 |
| CA2457545A1 (en) | 2003-05-01 |
| US20050214741A1 (en) | 2005-09-29 |
| EP1437937B1 (de) | 2008-05-21 |
| US8137927B2 (en) | 2012-03-20 |
| WO2003035891A2 (en) | 2003-05-01 |
| EP1437937A4 (de) | 2005-11-30 |
| US20030077772A1 (en) | 2003-04-24 |
| US7192766B2 (en) | 2007-03-20 |
| US20050006807A1 (en) | 2005-01-13 |
| EP1437937A2 (de) | 2004-07-21 |
| US8187851B2 (en) | 2012-05-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE396278T1 (de) | Verfahren zur herstellung eines sensors | |
| DE69812403D1 (de) | Verfahren zur herstellung einer waschmitteltablette | |
| DE60005233D1 (de) | Vorrichtung zur Herstellung und Zuführung eines unvulkanisierten Gummibandes | |
| DE68923727D1 (de) | Verfahren zur Herstellung eines aktiven Matrixsubstrats. | |
| DE60328421D1 (de) | Verfahren zur herstellung von super-hydrophoben oberflächen, daraus hergestellte oberflächen und deren verwendung | |
| DE60113871D1 (de) | Verfahren zur herstellung eines radioaktiven elementes zur brachytherapie | |
| ATE446306T1 (de) | Verfahren zur herstellung gepfropfter polylysin- dendrimere | |
| ATE390113T1 (de) | Verwendung von abformmassen zur herstellung von behandlungsvorrichtungen | |
| DE50108707D1 (de) | Verfahren zur herstellung kautschukhaltiger thermoplastischer formmassen | |
| BR0110696B1 (pt) | composição polimérica, seu processo de produção, seu uso, processo para produção de corpos moldados de ação antiestática e corpo moldado. | |
| ATE461226T1 (de) | Verfahren zur herstellung von polyacrolein | |
| DE50014164D1 (de) | Verfahren zur herstellung einer wasserunlöslichen amorphen retardmatrix | |
| DE59008642D1 (de) | Vorrichtung zum Einbringen eines Gases in den Hohlraum einer Spritzform zur Herstellung hohler Kunststoffkörper. | |
| DE3788900D1 (de) | Verfahren zur Herstellung eines länglichen gesinterten Farmkörpers. | |
| DE60143010D1 (de) | Vorrichtung zur Herstellung eines unvulkanisierten Gummibandes | |
| ATE387906T1 (de) | Verfahren zur herstellung unterschiedlicher fester dosierungsformen | |
| BRPI0406722A (pt) | Processo para purificação de um monomêro por extração com um agente formador de fases e cristalização, uso dos monÈmeros obtidos e dispositivo de sìntese | |
| ATE516142T1 (de) | Verfahren und vorrichtung zur herstellung einer lauffläche für einen reifen | |
| ATE273783T1 (de) | Verfahren und vorrichtung zur bereitstellung eines granulatgemisches, und granulatgemisch | |
| DE69930300D1 (de) | Verfahren zur herstellung eines auffindbaren ohrstöpsels | |
| ATE271579T1 (de) | 3d-matrix zur herstellung von zelltransplantaten | |
| DE60035130D1 (de) | Verfahren zur Herstellung eines photochromen, gehärteten Produkts | |
| ATE285293T1 (de) | Poröse organische polymerformkörper | |
| ATE476515T1 (de) | Verfahren zur herstellung eines testelements | |
| ATE248807T1 (de) | Verfahren zur herstellung von n-hydrocarbyl- substituierten amiden |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |