ATE396736T1 - High-density -lipoprotein zur behandlung von schlaganfällen und ischämiezuständen - Google Patents
High-density -lipoprotein zur behandlung von schlaganfällen und ischämiezuständenInfo
- Publication number
- ATE396736T1 ATE396736T1 AT02774525T AT02774525T ATE396736T1 AT E396736 T1 ATE396736 T1 AT E396736T1 AT 02774525 T AT02774525 T AT 02774525T AT 02774525 T AT02774525 T AT 02774525T AT E396736 T1 ATE396736 T1 AT E396736T1
- Authority
- AT
- Austria
- Prior art keywords
- stroke
- treatment
- density lipoprotein
- ischemia conditions
- ischemia
- Prior art date
Links
- 238000011282 treatment Methods 0.000 title abstract 2
- 102000015779 HDL Lipoproteins Human genes 0.000 title 1
- 108010010234 HDL Lipoproteins Proteins 0.000 title 1
- 208000028867 ischemia Diseases 0.000 title 1
- 208000006011 Stroke Diseases 0.000 abstract 1
- 238000001802 infusion Methods 0.000 abstract 1
- 238000001990 intravenous administration Methods 0.000 abstract 1
- 208000037906 ischaemic injury Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Marine Sciences & Fisheries (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Neurosurgery (AREA)
- Vascular Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Materials For Medical Uses (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31360501P | 2001-08-20 | 2001-08-20 | |
| EP01120026A EP1285662A1 (de) | 2001-08-20 | 2001-08-20 | Rekonstituiertes High-Density -Lipoprotein zur Behandlung von Schlaganfällen und Ischämiezuständen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE396736T1 true ATE396736T1 (de) | 2008-06-15 |
Family
ID=26076691
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02774525T ATE396736T1 (de) | 2001-08-20 | 2002-08-20 | High-density -lipoprotein zur behandlung von schlaganfällen und ischämiezuständen |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20040266660A1 (de) |
| EP (1) | EP1425031B8 (de) |
| JP (1) | JP4284177B2 (de) |
| AT (1) | ATE396736T1 (de) |
| AU (1) | AU2002340825B2 (de) |
| CA (1) | CA2457840C (de) |
| DE (1) | DE60226881D1 (de) |
| ES (1) | ES2304452T3 (de) |
| WO (1) | WO2003018047A2 (de) |
| ZA (1) | ZA200401360B (de) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL374126A1 (en) * | 2002-05-17 | 2005-10-03 | Esperion Therapeutics, Inc. | Methods and copositions for the treatment of ischemic reperfusion |
| US8206750B2 (en) | 2005-03-24 | 2012-06-26 | Cerenis Therapeutics Holding S.A. | Charged lipoprotein complexes and their uses |
| WO2007000924A1 (ja) * | 2005-06-28 | 2007-01-04 | Osaka University | プログラニュリン活性を抑制または促進する物質を含む医薬組成物、およびプログラニュリン活性を抑制または促進する物質のスクリーニング方法 |
| US20070110751A1 (en) * | 2005-10-25 | 2007-05-17 | Maclellan Robb | Compositions and methods for reducing infarct size |
| JP5601750B2 (ja) * | 2007-03-01 | 2014-10-08 | シーエスエル、リミテッド | 糖尿病患者の内皮機能異常の治療 |
| AU2007200908B2 (en) * | 2007-03-01 | 2012-08-16 | Csl Limited | Treatment of endothelial dysfunction in diabetic patients |
| CN102802618B (zh) | 2009-06-25 | 2014-06-18 | 泰特拉有限公司 | 烟酸和米曲肼的治疗组合 |
| EP2676659A1 (de) | 2009-07-16 | 2013-12-25 | INSERM (Institut National de la Santé et de la Recherche Médicale) | HDL mit einem Therapeutikum und Verwendung bei der Therapie |
| WO2011044545A2 (en) | 2009-10-09 | 2011-04-14 | Sigalov Alexander B | Methods and compositions for targeted imaging |
| US10894098B2 (en) | 2012-04-09 | 2021-01-19 | Signablok, Inc. | Methods and compositions for targeted imaging |
| US12419839B2 (en) | 2009-10-09 | 2025-09-23 | Signablok, Inc. | Methods and compositions for targeted delivery of protein fragments |
| WO2012103163A2 (en) * | 2011-01-25 | 2012-08-02 | The Cleveland Clinic Foundation | Compositions and methods for treating cancer while preventing or reducing cardiotoxicity and/or cardiomyopathy |
| DK2673296T3 (en) | 2011-02-07 | 2019-02-18 | Cerenis Therapeutics Holding Sa | LIPOPROTEIN COMPLEXES AND PREPARATION AND APPLICATIONS THEREOF |
| KR20140036167A (ko) * | 2011-03-25 | 2014-03-25 | 더 트러스티스 오브 컬럼비아 유니버시티 인 더 시티 오브 뉴욕 | 페길화된 인간 hdl 입자 및 그의 제조방법 |
| EP2853259A1 (de) | 2013-09-30 | 2015-04-01 | Université Pierre et Marie Curie (Paris 6) | Rekonstituierte hochdichte Lipoproteinzusammensetzung und Verwendungen davon |
| CA2947127A1 (en) | 2014-05-02 | 2015-11-19 | Cerenis Therapeutics Holding Sa | Hdl therapy markers |
| WO2019030574A1 (en) | 2017-08-10 | 2019-02-14 | Cerenis Therapeutics Holding | Cargomers |
| WO2019030575A1 (en) | 2017-08-10 | 2019-02-14 | Cerenis Therapeutics Holding | APOMÈRES |
| WO2021191266A1 (en) | 2020-03-25 | 2021-09-30 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Aerosolization of hdl for the treatment of lung infections |
| AU2021256086A1 (en) | 2020-04-16 | 2022-12-15 | Abionyx Pharma Sa | Methods for treating acute conditions using lipid binding protein- based complexes |
| WO2022069942A2 (en) | 2020-10-01 | 2022-04-07 | Abionyx Pharma Sa | Methods for treating eye diseases using lipid binding protein-based complexes |
| WO2022076324A1 (en) * | 2020-10-05 | 2022-04-14 | Northwestern University | Targeted ph sensitive liposomes |
| WO2022219413A1 (en) | 2021-04-15 | 2022-10-20 | Abionyx Pharma Sa | Use of lipid binding protein-based complexes in organ preservation solutions |
| WO2023194797A1 (en) | 2022-04-06 | 2023-10-12 | Abionyx Pharma Sa | Methods for treating eye diseases using lipid binding protein-based complexes |
| KR20240171131A (ko) | 2022-04-06 | 2024-12-06 | 아비오닉스 파마 에스에이 | 지질 결합 단백질-기반 복합체를 사용하여 백혈구증가증, 내피 기능장애 및 심장염을 치료하는 방법 |
| JP2025519606A (ja) | 2022-06-10 | 2025-06-26 | アビオニクス ファーマ エスエー | 脂質結合タンパク質に基づく複合体を使用して急性状態を処置するための方法 |
| IL317448A (en) | 2022-06-10 | 2025-02-01 | Abionyx Pharma Sa | Methods for treating hyperinflammatory conditions using complexes based on lipid-binding proteins |
| CN121219001A (zh) | 2023-01-13 | 2025-12-26 | 阿比奥尼克斯制药公司 | 脂质结合蛋白分子疗法 |
| WO2025093929A1 (en) | 2023-10-31 | 2025-05-08 | Abionyx Pharma Sa | Lipid binding protein molecule therapy |
| WO2026008645A1 (en) | 2024-07-02 | 2026-01-08 | Institut National de la Santé et de la Recherche Médicale | Aerosolization of apolipoprotein a1 nanoparticles enriched with alpha-1-antitrypsin for the treatment of pulmonary emphysema in patients suffering from alpha-1 antitrypsin deficiency |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19547648A1 (de) * | 1995-12-20 | 1997-06-26 | Hoechst Ag | Zubereitung, enthaltend High Density Lipoproteine und Crotonsäureamidderivate |
| EP1212065A4 (de) * | 1999-07-08 | 2004-02-11 | Tularik Inc | Zusammenstellungen und methoden zur erhöhung des hdl cholesterolspiegels |
| GB9919713D0 (en) * | 1999-08-19 | 1999-10-20 | Queen Mary & Westfield College | New medical use of high density lipoprotein |
| AUPQ429399A0 (en) | 1999-11-26 | 1999-12-23 | Heart Research Institute, The | Oxidized apolipoproteins and methods of use |
-
2002
- 2002-08-20 US US10/487,224 patent/US20040266660A1/en not_active Abandoned
- 2002-08-20 DE DE60226881T patent/DE60226881D1/de not_active Expired - Lifetime
- 2002-08-20 CA CA2457840A patent/CA2457840C/en not_active Expired - Fee Related
- 2002-08-20 AT AT02774525T patent/ATE396736T1/de active
- 2002-08-20 WO PCT/EP2002/009294 patent/WO2003018047A2/en not_active Ceased
- 2002-08-20 EP EP02774525A patent/EP1425031B8/de not_active Expired - Lifetime
- 2002-08-20 JP JP2003522564A patent/JP4284177B2/ja not_active Expired - Fee Related
- 2002-08-20 AU AU2002340825A patent/AU2002340825B2/en not_active Ceased
- 2002-08-20 ES ES02774525T patent/ES2304452T3/es not_active Expired - Lifetime
-
2004
- 2004-02-19 ZA ZA2004/01360A patent/ZA200401360B/en unknown
-
2007
- 2007-05-04 US US11/744,780 patent/US7491693B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003018047A2 (en) | 2003-03-06 |
| ZA200401360B (en) | 2005-08-31 |
| EP1425031A2 (de) | 2004-06-09 |
| EP1425031B1 (de) | 2008-05-28 |
| US20040266660A1 (en) | 2004-12-30 |
| JP2005501110A (ja) | 2005-01-13 |
| DE60226881D1 (de) | 2008-07-10 |
| WO2003018047A3 (en) | 2004-01-29 |
| JP4284177B2 (ja) | 2009-06-24 |
| ES2304452T3 (es) | 2008-10-16 |
| EP1425031B8 (de) | 2008-09-03 |
| CA2457840A1 (en) | 2003-03-06 |
| HK1064304A1 (en) | 2005-01-28 |
| US20080108550A1 (en) | 2008-05-08 |
| CA2457840C (en) | 2011-10-11 |
| US7491693B2 (en) | 2009-02-17 |
| AU2002340825B2 (en) | 2007-07-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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