ATE397600T1 - Diastereoselektives syntheseverfahren zur herstellung vn imidazolverbindungen - Google Patents

Diastereoselektives syntheseverfahren zur herstellung vn imidazolverbindungen

Info

Publication number
ATE397600T1
ATE397600T1 AT05737841T AT05737841T ATE397600T1 AT E397600 T1 ATE397600 T1 AT E397600T1 AT 05737841 T AT05737841 T AT 05737841T AT 05737841 T AT05737841 T AT 05737841T AT E397600 T1 ATE397600 T1 AT E397600T1
Authority
AT
Austria
Prior art keywords
methyl
synthesis process
production
sub
imidazole compounds
Prior art date
Application number
AT05737841T
Other languages
English (en)
Inventor
Walter Ferdinand Mari Filliers
Rudy Laurent Maria Broeckx
Patrick Rene Angibaud
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of ATE397600T1 publication Critical patent/ATE397600T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT05737841T 2004-05-03 2005-04-28 Diastereoselektives syntheseverfahren zur herstellung vn imidazolverbindungen ATE397600T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04076319 2004-05-03

Publications (1)

Publication Number Publication Date
ATE397600T1 true ATE397600T1 (de) 2008-06-15

Family

ID=34966069

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05737841T ATE397600T1 (de) 2004-05-03 2005-04-28 Diastereoselektives syntheseverfahren zur herstellung vn imidazolverbindungen

Country Status (10)

Country Link
US (1) US7456287B2 (de)
EP (1) EP1751137B1 (de)
JP (1) JP5008554B2 (de)
CN (1) CN100567292C (de)
AT (1) ATE397600T1 (de)
AU (1) AU2005238223B2 (de)
CA (1) CA2563807C (de)
DE (1) DE602005007346D1 (de)
ES (1) ES2308486T3 (de)
WO (1) WO2005105784A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20211976T1 (hr) 2015-08-17 2022-03-18 Kura Oncology, Inc. Postupci liječenja bolesnika od raka inhibitorima farnezil transferaze
EP3838275A1 (de) 2016-11-03 2021-06-23 Kura Oncology, Inc. Farnesyltransferase-inhibitoren zur verwendung bei der behandlung von krebs
CN110234639A (zh) 2016-12-08 2019-09-13 杭州领业医药科技有限公司 替吡法尼的晶型及其制备方法及药物组合物
AU2019270163A1 (en) 2018-05-18 2020-12-03 Kura Oncology, Inc. Synthesis of tipifarnib

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2175137T3 (es) * 1995-12-08 2002-11-16 Janssen Pharmaceutica Nv Derivados de (imidazol-5-il)metil-2-quinolinona como inhibidores de laproteina farnesil-transferasa.
HN2000000266A (es) 2000-01-21 2001-05-21 Pfizer Prod Inc Compuesto anticanceroso y metodo de separacion de enantiomeros util para sintetizar dicho compuesto.
CA2438421C (en) 2001-03-12 2010-05-18 Janssen Pharmaceutica N.V. Process for the preparation of imidazole compounds
WO2003104186A1 (ja) * 2002-06-11 2003-12-18 鐘淵化学工業株式会社 光学活性β−アミノアルコールの製造法

Also Published As

Publication number Publication date
WO2005105784A1 (en) 2005-11-10
EP1751137B1 (de) 2008-06-04
ES2308486T3 (es) 2008-12-01
CA2563807C (en) 2012-11-20
DE602005007346D1 (de) 2008-07-17
CN1946711A (zh) 2007-04-11
CN100567292C (zh) 2009-12-09
JP5008554B2 (ja) 2012-08-22
CA2563807A1 (en) 2005-11-10
EP1751137A1 (de) 2007-02-14
AU2005238223A1 (en) 2005-11-10
JP2007536335A (ja) 2007-12-13
US7456287B2 (en) 2008-11-25
US20070238880A1 (en) 2007-10-11
AU2005238223B2 (en) 2012-04-26
HK1101580A1 (zh) 2007-10-18

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Legal Events

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