ATE397603T1 - Herstellungsverfahren von kristallinem losartan- kaliumsalz - Google Patents

Herstellungsverfahren von kristallinem losartan- kaliumsalz

Info

Publication number
ATE397603T1
ATE397603T1 AT04027598T AT04027598T ATE397603T1 AT E397603 T1 ATE397603 T1 AT E397603T1 AT 04027598 T AT04027598 T AT 04027598T AT 04027598 T AT04027598 T AT 04027598T AT E397603 T1 ATE397603 T1 AT E397603T1
Authority
AT
Austria
Prior art keywords
losartan potassium
production process
potassium salt
crystalline losartan
crystalline
Prior art date
Application number
AT04027598T
Other languages
English (en)
Inventor
Gabriele Razetti
Domenico Magrone
Mauro Ercoli
Pietro Allegrini
Graziano Castaldi
Original Assignee
Dipharma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dipharma Spa filed Critical Dipharma Spa
Application granted granted Critical
Publication of ATE397603T1 publication Critical patent/ATE397603T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT04027598T 2003-12-16 2004-11-19 Herstellungsverfahren von kristallinem losartan- kaliumsalz ATE397603T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT002472A ITMI20032472A1 (it) 2003-12-16 2003-12-16 Procedimento per la preparazione di losartan potassio cristallino

Publications (1)

Publication Number Publication Date
ATE397603T1 true ATE397603T1 (de) 2008-06-15

Family

ID=34509471

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04027598T ATE397603T1 (de) 2003-12-16 2004-11-19 Herstellungsverfahren von kristallinem losartan- kaliumsalz

Country Status (7)

Country Link
US (1) US20050131040A1 (de)
EP (1) EP1544198B1 (de)
JP (1) JP2005179355A (de)
AT (1) ATE397603T1 (de)
DE (1) DE602004014237D1 (de)
ES (1) ES2306949T3 (de)
IT (1) ITMI20032472A1 (de)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0736021A4 (de) * 1993-12-23 1997-04-02 Merck & Co Inc Polymorphe von losartan und verfahren zur herstellung von form ii losartan
WO1998018787A1 (en) * 1996-10-29 1998-05-07 Merck & Co., Inc. Process for the crystallization of losartan
SI21236A (sl) * 2001-05-18 2003-12-31 Aurobindo Pharma Limited Postopek kristalizacije losartan kalija
KR20050044450A (ko) * 2001-11-14 2005-05-12 테바 파마슈티컬 인더스트리즈 리미티드 로사르탄 칼륨의 무정형 및 결정형 형태 및 이의 제조 방법
SI1589966T1 (sl) * 2003-01-30 2011-06-30 Lek Pharmaceuticals D.D. Postopek čiščenja losartana

Also Published As

Publication number Publication date
DE602004014237D1 (de) 2008-07-17
EP1544198A1 (de) 2005-06-22
ITMI20032472A1 (it) 2005-06-17
EP1544198B1 (de) 2008-06-04
US20050131040A1 (en) 2005-06-16
ES2306949T3 (es) 2008-11-16
JP2005179355A (ja) 2005-07-07

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties