ATE398468T1 - Mittel zur wundbehandlung - Google Patents
Mittel zur wundbehandlungInfo
- Publication number
- ATE398468T1 ATE398468T1 AT00909315T AT00909315T ATE398468T1 AT E398468 T1 ATE398468 T1 AT E398468T1 AT 00909315 T AT00909315 T AT 00909315T AT 00909315 T AT00909315 T AT 00909315T AT E398468 T1 ATE398468 T1 AT E398468T1
- Authority
- AT
- Austria
- Prior art keywords
- polymer
- fibers
- layer
- natural
- medium
- Prior art date
Links
- 239000000835 fiber Substances 0.000 abstract 4
- 239000002131 composite material Substances 0.000 abstract 3
- 239000006260 foam Substances 0.000 abstract 3
- 206010052428 Wound Diseases 0.000 abstract 2
- 208000027418 Wounds and injury Diseases 0.000 abstract 2
- 229920005615 natural polymer Polymers 0.000 abstract 2
- 229920000642 polymer Polymers 0.000 abstract 2
- 229920005594 polymer fiber Polymers 0.000 abstract 2
- 229920001059 synthetic polymer Polymers 0.000 abstract 2
- 239000000463 material Substances 0.000 abstract 1
- 230000000149 penetrating effect Effects 0.000 abstract 1
- 239000011148 porous material Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 230000029663 wound healing Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/425—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/225—Mixtures of macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
- A61L15/325—Collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Materials Engineering (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Biological Treatment Of Waste Water (AREA)
- Treatments Of Macromolecular Shaped Articles (AREA)
- Electric Double-Layer Capacitors Or The Like (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Soil Working Implements (AREA)
- Laser Surgery Devices (AREA)
- Surgical Instruments (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2000/001905 WO2001064258A1 (en) | 2000-03-03 | 2000-03-03 | Agent for the treatment of wounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE398468T1 true ATE398468T1 (de) | 2008-07-15 |
Family
ID=8163862
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00909315T ATE398468T1 (de) | 2000-03-03 | 2000-03-03 | Mittel zur wundbehandlung |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6855860B2 (de) |
| EP (1) | EP1259269B1 (de) |
| JP (1) | JP2003525083A (de) |
| AT (1) | ATE398468T1 (de) |
| AU (1) | AU2000231640A1 (de) |
| CA (1) | CA2401869A1 (de) |
| DE (1) | DE60039256D1 (de) |
| DK (1) | DK1259269T3 (de) |
| ES (1) | ES2304343T3 (de) |
| WO (1) | WO2001064258A1 (de) |
Families Citing this family (77)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060004314A1 (en) * | 2001-06-14 | 2006-01-05 | Hemcon, Inc. | Antimicrobial barriers, systems, and methods formed from hydrophilic polymer structures such as chistosan |
| US7371403B2 (en) * | 2002-06-14 | 2008-05-13 | Providence Health System-Oregon | Wound dressing and method for controlling severe, life-threatening bleeding |
| US8741335B2 (en) | 2002-06-14 | 2014-06-03 | Hemcon Medical Technologies, Inc. | Hemostatic compositions, assemblies, systems, and methods employing particulate hemostatic agents formed from hydrophilic polymer foam such as Chitosan |
| KR100953465B1 (ko) * | 2001-06-14 | 2010-04-16 | 프로비던스 헬스 시스템-오레곤 | 상처 드레싱과 생명을 위협하는 심각한 출혈을 조절하는방법 |
| US20050137512A1 (en) * | 2003-12-23 | 2005-06-23 | Campbell Todd D. | Wound dressing and method for controlling severe, life-threatening bleeding |
| US8269058B2 (en) * | 2002-06-14 | 2012-09-18 | Hemcon Medical Technologies, Inc. | Absorbable tissue dressing assemblies, systems, and methods formed from hydrophilic polymer sponge structures such as chitosan |
| US7846141B2 (en) | 2002-09-03 | 2010-12-07 | Bluesky Medical Group Incorporated | Reduced pressure treatment system |
| GB0224986D0 (en) | 2002-10-28 | 2002-12-04 | Smith & Nephew | Apparatus |
| GB0325129D0 (en) | 2003-10-28 | 2003-12-03 | Smith & Nephew | Apparatus in situ |
| US20050100571A1 (en) * | 2003-11-10 | 2005-05-12 | Larry Keyes | Method and device to treat skin affected by a corn |
| US20070020324A1 (en) * | 2003-11-10 | 2007-01-25 | Larry Keyes | Method and device to treat skin affected by a corn |
| US8920443B2 (en) | 2004-02-17 | 2014-12-30 | Cook Biotech Incorporated | Medical devices and methods useful for applying bolster material |
| AU2005231781A1 (en) * | 2004-03-31 | 2005-10-20 | Cook Incorporated | ECM-based graft material |
| US7909805B2 (en) | 2004-04-05 | 2011-03-22 | Bluesky Medical Group Incorporated | Flexible reduced pressure treatment appliance |
| US10058642B2 (en) * | 2004-04-05 | 2018-08-28 | Bluesky Medical Group Incorporated | Reduced pressure treatment system |
| US8062272B2 (en) | 2004-05-21 | 2011-11-22 | Bluesky Medical Group Incorporated | Flexible reduced pressure treatment appliance |
| DE102004063599B4 (de) * | 2004-12-30 | 2007-07-12 | Bayer Innovation Gmbh | Verkürzte Wundheilungsprozesse mittels neuartiger Faservliese |
| US9204957B2 (en) * | 2005-03-17 | 2015-12-08 | Hemcon Medical Technologies, Inc. | Systems and methods for hemorrhage control and or tissue repair |
| BRPI0615715A2 (pt) | 2005-09-06 | 2011-05-24 | Tyco Healthcare | curativo de ferimento independente com microbomba |
| EP2898908A1 (de) | 2005-09-07 | 2015-07-29 | Smith & Nephew, Inc. | Abgeschlossenes Wundverbandgerät |
| AU2006287460A1 (en) | 2005-09-07 | 2007-03-15 | Tyco Healthcare Group Lp | Wound dressing with vacuum reservoir |
| US10166147B2 (en) * | 2005-11-02 | 2019-01-01 | Bsn Medical Gmbh | Absorbent article for application to human or animal skin surfaces |
| DE102005054940A1 (de) * | 2005-11-17 | 2007-05-24 | Gelita Ag | Verbundmaterial, insbesondere für die medizinische Anwendung , und Verfahren zu dessen Herstellung |
| DE102005054943A1 (de) * | 2005-11-17 | 2007-05-24 | Gelita Ag | Verfahren zur Herstellung eines Hohlprofils auf Basis eines vernetzten, Gelatine enthaltenden Materials sowie Implantate in Form von Hohlprofilen |
| DE102005054941A1 (de) * | 2005-11-17 | 2007-05-31 | Gelita Ag | Nervenleitschiene |
| GB2433029A (en) * | 2005-12-09 | 2007-06-13 | Ethicon Inc | Wound dressings comprising oxidized cellulose and human recombinant collagen |
| JP2009528437A (ja) * | 2006-03-01 | 2009-08-06 | エフエムシー バイオポリマー エイエス | 生分解性発泡体 |
| US20070218038A1 (en) | 2006-03-17 | 2007-09-20 | Pegasus Biologics, Inc. | Stabilized, sterilized collagen scaffolds with active adjuncts attached |
| JP2009538192A (ja) | 2006-05-23 | 2009-11-05 | プロビデンス ヘルス システム−オレゴン ディー/ビー/エー プロビデンス セント ビンセント メディカル センター | 体の内腔または体の中空器官内に包帯構造を導入および適用するシステムおよび方法 |
| US9198995B2 (en) | 2006-09-20 | 2015-12-01 | Ore-Medix Llc | Conformable structured therapeutic dressing |
| US7758476B2 (en) * | 2007-02-06 | 2010-07-20 | Fitness Botics | Inflatable cushion bag for striking |
| US20080260794A1 (en) * | 2007-02-12 | 2008-10-23 | Lauritzen Nels J | Collagen products and methods for producing collagen products |
| US9056151B2 (en) * | 2007-02-12 | 2015-06-16 | Warsaw Orthopedic, Inc. | Methods for collagen processing and products using processed collagen |
| US7790946B2 (en) * | 2007-07-06 | 2010-09-07 | Tyco Healthcare Group Lp | Subatmospheric pressure wound therapy dressing |
| US8460258B2 (en) * | 2008-01-08 | 2013-06-11 | Southeastern Medical Technologies, Llc | Methods and apparatuses for the treatment of wounds with pressures altered from atmospheric |
| US8709393B2 (en) | 2008-01-30 | 2014-04-29 | Wound Engineering Llc | Methods and compositions for wound healing |
| US8021347B2 (en) | 2008-07-21 | 2011-09-20 | Tyco Healthcare Group Lp | Thin film wound dressing |
| US8298200B2 (en) | 2009-06-01 | 2012-10-30 | Tyco Healthcare Group Lp | System for providing continual drainage in negative pressure wound therapy |
| CA2721507C (en) | 2008-04-18 | 2017-10-03 | Collplant Ltd. | Methods of generating and using procollagen |
| WO2009134447A1 (en) | 2008-05-02 | 2009-11-05 | Providence Health System-Oregon D/B/A Providence St. Vincent Medical Center | Wound dressing devices and methods |
| US8257326B2 (en) * | 2008-06-30 | 2012-09-04 | Tyco Healthcare Group Lp | Apparatus for enhancing wound healing |
| EP2300069B1 (de) * | 2008-07-08 | 2017-12-13 | Smith & Nephew, Inc | Tragbare unterdruck-wundtherapievorrichtung |
| HUE037556T2 (hu) * | 2008-08-08 | 2018-09-28 | Smith & Nephew Inc | Sebkötözõ folytonos szálakból |
| US9414968B2 (en) | 2008-09-05 | 2016-08-16 | Smith & Nephew, Inc. | Three-dimensional porous film contact layer with improved wound healing |
| JP5788323B2 (ja) * | 2008-10-02 | 2015-09-30 | エル.アール. アールアンドディー リミテッド | 界面層の創傷包帯 |
| EP2340002B1 (de) | 2008-10-06 | 2015-03-25 | Providence Health System - Oregon | Medizinische schaumvorrichtungen und verfahren |
| US20100191198A1 (en) * | 2009-01-26 | 2010-07-29 | Tyco Healthcare Group Lp | Wound Filler Material with Improved Nonadherency Properties |
| US20100204752A1 (en) * | 2009-02-10 | 2010-08-12 | Tyco Healthcare Group Lp | Negative Pressure and Electrostimulation Therapy Apparatus |
| KR101019714B1 (ko) * | 2009-04-01 | 2011-03-07 | 쓰리디이미징앤시뮬레이션즈(주) | 디지털 엑스레이 영상 획득장치 |
| US8858983B2 (en) | 2009-04-30 | 2014-10-14 | Medtronic, Inc. | Antioxidants and antimicrobial accessories including antioxidants |
| US20110196321A1 (en) | 2009-06-10 | 2011-08-11 | Tyco Healthcare Group Lp | Fluid Collection Canister Including Canister Top with Filter Membrane and Negative Pressure Wound Therapy Systems Including Same |
| US20100318043A1 (en) * | 2009-06-10 | 2010-12-16 | Tyco Healthcare Group Lp | Negative Pressure Wound Therapy Systems Capable of Vacuum Measurement Independent of Orientation |
| US20100318071A1 (en) * | 2009-06-10 | 2010-12-16 | Tyco Healthcare Group Lp | Fluid Collection Canister Including Canister Top with Filter Membrane and Negative Pressure Wound Therapy Systems Including Same |
| US20100324516A1 (en) * | 2009-06-18 | 2010-12-23 | Tyco Healthcare Group Lp | Apparatus for Vacuum Bridging and/or Exudate Collection |
| JP5281715B2 (ja) * | 2009-08-05 | 2013-09-04 | コヴィディエン リミテッド パートナーシップ | 内部に埋め込まれた電極を有する接続ハイドロゲルビードを組み込む外科用創傷被覆 |
| US20110106027A1 (en) * | 2009-11-05 | 2011-05-05 | Tyco Healthcare Group Lp | Chemically Coated Screen for Use with Hydrophobic Filters |
| EP2533772B1 (de) | 2010-02-10 | 2021-09-08 | Imbed Biosciences, Inc. | Verfahren und zusammensetzungen zur wundheilung |
| US8790699B2 (en) | 2010-04-23 | 2014-07-29 | Warsaw Orthpedic, Inc. | Foam-formed collagen strand |
| US8460691B2 (en) | 2010-04-23 | 2013-06-11 | Warsaw Orthopedic, Inc. | Fenestrated wound repair scaffold |
| US8911427B2 (en) | 2010-12-28 | 2014-12-16 | Medtronic, Inc. | Therapeutic agent reservoir delivery system |
| US9302034B2 (en) | 2011-04-04 | 2016-04-05 | Smith & Nephew, Inc. | Negative pressure wound therapy dressing |
| MX342577B (es) | 2011-06-07 | 2016-10-04 | Smith & Nephew | Miembros y métodos de contacto de heridas. |
| US20130011451A1 (en) * | 2011-07-06 | 2013-01-10 | Diversified Glogal Technologies, Llc | Footbed with non-denatured collagen |
| EP2545943A1 (de) | 2011-07-12 | 2013-01-16 | Dr. Suwelack Skin & Health Care AG | Perforiertes, geschichtetes Wundbehandlungsmaterial |
| US10576694B2 (en) | 2011-12-08 | 2020-03-03 | Julius-Maximilians-Universitaet Wuerzburg | Production of materials having an anisotropic structure |
| EP2788171B1 (de) * | 2011-12-08 | 2021-02-17 | Stuckensen, Kai | Herstellung anisotrop strukturierter werkstoffe |
| ITMI20130883A1 (it) * | 2013-05-30 | 2014-12-01 | Eurores S R L | Composizioni farmaceutiche comprendenti collagene e sodio ialuronato |
| US11007082B2 (en) * | 2014-07-23 | 2021-05-18 | Innovative Therapies Inc. | Foam laminate dressing |
| US11273077B2 (en) | 2015-04-25 | 2022-03-15 | Chemokind, Inc. | Wound packing material comprising chemoeffector |
| ITUB20156791A1 (it) * | 2015-12-09 | 2017-06-09 | Euroresearch Srl | Dispositivo medicale. |
| EP3228330A1 (de) * | 2016-04-08 | 2017-10-11 | Mölnlycke Health Care AB | Verbundwerkstoffe bei der wundbehandlung |
| US11554194B2 (en) | 2016-07-29 | 2023-01-17 | Imbed Biosciences Inc. | Methods and compositions for wound healing |
| WO2019157466A1 (en) | 2018-02-12 | 2019-08-15 | Healyx Labs, Inc. | Negative pressure wound therapy systems, devices, and methods |
| CN114681663B (zh) * | 2020-12-31 | 2023-05-05 | 广州迈普再生医学科技股份有限公司 | 多功能复合创面敷料及其制备方法 |
| CN113101009B (zh) * | 2021-04-19 | 2023-05-30 | 河南亚都实业有限公司 | 一种医疗用人工皮肤涂敷器装置 |
| AU2024225575A1 (en) | 2023-02-21 | 2025-08-07 | Osteal Therapeutics, Inc. | Systems and devices for treatment of localized infection in and around articulating joints and methods of use |
| CN120459364B (zh) * | 2025-05-30 | 2026-02-03 | 咸阳雅尔艾服装有限公司 | 一种泡沫敷料及其制备方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3900027A (en) * | 1974-01-02 | 1975-08-19 | Pall Corp | Process for preparing integral absorbent pad bandages and product |
| US4060081A (en) * | 1975-07-15 | 1977-11-29 | Massachusetts Institute Of Technology | Multilayer membrane useful as synthetic skin |
| US4265233A (en) * | 1978-04-12 | 1981-05-05 | Unitika Ltd. | Material for wound healing |
| DE3037513C2 (de) | 1980-10-03 | 1983-05-05 | Steffan, Wolfgang, 8425 Neustadt | Kollagene Wundauflage |
| US4578067A (en) | 1982-04-12 | 1986-03-25 | Alcon (Puerto Rico) Inc. | Hemostatic-adhesive, collagen dressing for severed biological surfaces |
| US4660553A (en) * | 1982-07-06 | 1987-04-28 | Dow Corning Ltd. | Medical-surgical dressing and a process for the production thereof |
| US4925924A (en) | 1984-03-27 | 1990-05-15 | University Of Medicine And Dentistry Of New Jersey | Biocompatible synthetic and collagen compositions having a dual-type porosity for treatment of wounds and pressure ulcers and therapeutic methods thereof |
| US4965203A (en) * | 1987-01-28 | 1990-10-23 | Warner-Lambert Company | Purified thrombin preparations |
| US5290552A (en) * | 1988-05-02 | 1994-03-01 | Matrix Pharmaceutical, Inc./Project Hear | Surgical adhesive material |
| GB2272645B8 (en) * | 1992-11-23 | 2010-02-10 | Johnson & Johnson Medical | Wound dressing |
| US5556391A (en) * | 1993-10-01 | 1996-09-17 | Merocel Corporation | Surgical sponge device |
| DE69530553T2 (de) * | 1994-05-13 | 2004-03-25 | KURARAY CO., LTD, Kurashiki | Medizinisches polymergel |
| JPH0833672A (ja) * | 1994-07-22 | 1996-02-06 | Terumo Corp | 創傷被覆材 |
| US5709934A (en) * | 1994-11-22 | 1998-01-20 | Tissue Engineering, Inc. | Bipolymer foams having extracellular matrix particulates |
| DE19542687A1 (de) * | 1995-11-16 | 1997-05-22 | Siegel Rolf | Herstellungsverfahren für offen-porige Formkörper sowie Verwendung der Verfahrenserzeugnisse |
| US5928174A (en) * | 1997-11-14 | 1999-07-27 | Acrymed | Wound dressing device |
| AU2002316694B2 (en) * | 2001-07-16 | 2007-09-06 | Depuy Products, Inc. | Hybrid biologic/synthetic porous extracellular matrix scaffolds |
-
2000
- 2000-03-03 EP EP00909315A patent/EP1259269B1/de not_active Expired - Lifetime
- 2000-03-03 DE DE60039256T patent/DE60039256D1/de not_active Expired - Lifetime
- 2000-03-03 WO PCT/EP2000/001905 patent/WO2001064258A1/en not_active Ceased
- 2000-03-03 ES ES00909315T patent/ES2304343T3/es not_active Expired - Lifetime
- 2000-03-03 AT AT00909315T patent/ATE398468T1/de active
- 2000-03-03 DK DK00909315T patent/DK1259269T3/da active
- 2000-03-03 JP JP2001563155A patent/JP2003525083A/ja active Pending
- 2000-03-03 CA CA002401869A patent/CA2401869A1/en not_active Abandoned
- 2000-03-03 AU AU2000231640A patent/AU2000231640A1/en not_active Abandoned
-
2002
- 2002-08-30 US US10/231,667 patent/US6855860B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2000231640A1 (en) | 2001-09-12 |
| US6855860B2 (en) | 2005-02-15 |
| CA2401869A1 (en) | 2001-09-07 |
| WO2001064258A1 (en) | 2001-09-07 |
| JP2003525083A (ja) | 2003-08-26 |
| EP1259269B1 (de) | 2008-06-18 |
| DK1259269T3 (da) | 2008-10-20 |
| EP1259269A1 (de) | 2002-11-27 |
| DE60039256D1 (de) | 2008-07-31 |
| ES2304343T3 (es) | 2008-10-16 |
| US20030078532A1 (en) | 2003-04-24 |
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