ATE401081T1 - Ammoniumsalze von ornithin-derivaten zur behandlung von enzündlichen erkrankungen - Google Patents

Ammoniumsalze von ornithin-derivaten zur behandlung von enzündlichen erkrankungen

Info

Publication number
ATE401081T1
ATE401081T1 AT04713788T AT04713788T ATE401081T1 AT E401081 T1 ATE401081 T1 AT E401081T1 AT 04713788 T AT04713788 T AT 04713788T AT 04713788 T AT04713788 T AT 04713788T AT E401081 T1 ATE401081 T1 AT E401081T1
Authority
AT
Austria
Prior art keywords
ammonium salts
treatment
inflammatory diseases
delta
ornithine
Prior art date
Application number
AT04713788T
Other languages
English (en)
Inventor
Lindsay Rosenwald
Michael Weiser
Jason Stein
Jeff Serbin
Original Assignee
Hana Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hana Biosciences Inc filed Critical Hana Biosciences Inc
Application granted granted Critical
Publication of ATE401081T1 publication Critical patent/ATE401081T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT04713788T 2003-08-06 2004-02-23 Ammoniumsalze von ornithin-derivaten zur behandlung von enzündlichen erkrankungen ATE401081T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/634,811 US20050032807A1 (en) 2003-08-06 2003-08-06 Methods of treating inflammatory diseases with ammonium salts of ornitihine derivatives

Publications (1)

Publication Number Publication Date
ATE401081T1 true ATE401081T1 (de) 2008-08-15

Family

ID=34116103

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04713788T ATE401081T1 (de) 2003-08-06 2004-02-23 Ammoniumsalze von ornithin-derivaten zur behandlung von enzündlichen erkrankungen

Country Status (10)

Country Link
US (1) US20050032807A1 (de)
EP (1) EP1660093B1 (de)
JP (1) JP2007501227A (de)
KR (1) KR20070029101A (de)
AT (1) ATE401081T1 (de)
AU (1) AU2004264785A1 (de)
CA (1) CA2534558A1 (de)
DE (1) DE602004015116D1 (de)
WO (1) WO2005016350A1 (de)
ZA (1) ZA200601180B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040259878A1 (en) * 2003-02-13 2004-12-23 Jason Koutcher Fluoromethotrexates and uses therefor

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4767761A (en) * 1987-11-04 1988-08-30 Dana-Farber Cancer Institute, Inc. Ornithine derivatives and their use as methotrexate-resistant cell inhibitors
US4956461A (en) * 1988-10-19 1990-09-11 Dana Farber Cancer Institute, Inc. Desamino-aminopterin and -methotrexate
CH680731A5 (de) * 1990-04-12 1992-10-30 Sapec Fine Chemicals
US5149688A (en) * 1990-04-24 1992-09-22 Cetus Corporation Methods, compounds, and compositions for immunosuppression
JPH10310526A (ja) * 1997-05-09 1998-11-24 Iyaku Bunshi Sekkei Kenkyusho:Kk ジヒドロ葉酸還元酵素の阻害剤
US5912251A (en) * 1998-01-17 1999-06-15 Nair; Madhavan G. Metabolically inert anti-inflammatory and anti-tumor antifolates
HUP0201333A3 (en) * 1999-05-24 2004-11-29 Sankyo Company Ltd Chuo Ku Medicinal compositions containing anti-fas antibody
JP4270483B2 (ja) * 2000-11-20 2009-06-03 第一三共株式会社 カルバペネム系抗菌剤の製造方法
BR0207706A (pt) * 2001-02-28 2004-03-23 Melacure Therapeutics Ab ésteres de diaminoquinazolina para uso como inibidores da diidrofolato redutase
PE20030340A1 (es) * 2001-08-28 2003-04-05 Sankyo Co Metodo para el tratamiento o prevencion de desgaste oseo
US6989386B2 (en) * 2002-04-30 2006-01-24 Dana-Farber Cancer Institute Pharmaceutically active ornithine derivatives, ammonium salts thereof and methods of making same

Also Published As

Publication number Publication date
EP1660093A1 (de) 2006-05-31
CA2534558A1 (en) 2005-02-24
ZA200601180B (en) 2007-04-25
AU2004264785A1 (en) 2005-02-24
US20050032807A1 (en) 2005-02-10
KR20070029101A (ko) 2007-03-13
DE602004015116D1 (de) 2008-08-28
WO2005016350A1 (en) 2005-02-24
JP2007501227A (ja) 2007-01-25
EP1660093B1 (de) 2008-07-16

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Legal Events

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