ATE401898T1 - Phosphatidyl-l-serin und phosphatidylsäure zur behandlung von depression und stresszuständen - Google Patents

Phosphatidyl-l-serin und phosphatidylsäure zur behandlung von depression und stresszuständen

Info

Publication number: ATE401898T1
Authority: AT; Austria
Prior art keywords: serine; phosphatidic acid; lecithin; phosphatidyl; phosphatidy
Prior art date: 2000-10-23

Application number

AT01114833T

Other languages

English (en)

Inventor

David Rutenberg

Original Assignee

Lipogen Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-10-23

Filing date

2001-06-28

Publication date

2008-08-15

2001-06-28 Application filed by Lipogen Ltd filed Critical Lipogen Ltd

2008-08-15 Application granted granted Critical

2008-08-15 Publication of ATE401898T1 publication Critical patent/ATE401898T1/de

Links

208000020401 Depressive disease Diseases 0.000 title 1
239000002253 acid Substances 0.000 title 1
PORPENFLTBBHSG-MGBGTMOVSA-N 1,2-dihexadecanoyl-sn-glycerol-3-phosphate Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(O)=O)OC(=O)CCCCCCCCCCCCCCC PORPENFLTBBHSG-MGBGTMOVSA-N 0.000 abstract 5
229960001153 serine Drugs 0.000 abstract 5
IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 abstract 3
229940067606 lecithin Drugs 0.000 abstract 3
235000010445 lecithin Nutrition 0.000 abstract 3
239000000787 lecithin Substances 0.000 abstract 3
230000002996 emotional effect Effects 0.000 abstract 2
JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 abstract 2
230000003340 mental effect Effects 0.000 abstract 2
239000000203 mixture Substances 0.000 abstract 2
150000003904 phospholipids Chemical class 0.000 abstract 2
239000002994 raw material Substances 0.000 abstract 2
JQWAHKMIYCERGA-UHFFFAOYSA-N (2-nonanoyloxy-3-octadeca-9,12-dienoyloxypropoxy)-[2-(trimethylazaniumyl)ethyl]phosphinate Chemical compound CCCCCCCCC(=O)OC(COP([O-])(=O)CC[N+](C)(C)C)COC(=O)CCCCCCCC=CCC=CCCCCC JQWAHKMIYCERGA-UHFFFAOYSA-N 0.000 abstract 1
JLPULHDHAOZNQI-ZTIMHPMXSA-N 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/C\C=C/CCCCC JLPULHDHAOZNQI-ZTIMHPMXSA-N 0.000 abstract 1
240000002791 Brassica napus Species 0.000 abstract 1
235000004977 Brassica sinapistrum Nutrition 0.000 abstract 1
102000011420 Phospholipase D Human genes 0.000 abstract 1
108090000553 Phospholipase D Proteins 0.000 abstract 1
230000001430 anti-depressive effect Effects 0.000 abstract 1
239000000935 antidepressant agent Substances 0.000 abstract 1
239000008280 blood Substances 0.000 abstract 1
210000004369 blood Anatomy 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
230000003247 decreasing effect Effects 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000002255 enzymatic effect Effects 0.000 abstract 1
125000005313 fatty acid group Chemical group 0.000 abstract 1
229960000890 hydrocortisone Drugs 0.000 abstract 1
239000004615 ingredient Substances 0.000 abstract 1
230000036651 mood Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
230000000697 serotonin reuptake Effects 0.000 abstract 1
229940083466 soybean lecithin Drugs 0.000 abstract 1
239000000758 substrate Substances 0.000 abstract 1
208000024891 symptom Diseases 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Neurosurgery (AREA)
Food Science & Technology (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Polymers & Plastics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oil, Petroleum & Natural Gas (AREA)
Mycology (AREA)
Nutrition Science (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT01114833T 2000-10-23 2001-06-28 Phosphatidyl-l-serin und phosphatidylsäure zur behandlung von depression und stresszuständen ATE401898T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IL139224A IL139224A (en)	2000-10-23	2000-10-23	Anti depressant, stress suppressor and mood improver

Publications (1)

Publication Number	Publication Date
ATE401898T1 true ATE401898T1 (de)	2008-08-15

Family

ID=11074750

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01114833T ATE401898T1 (de)	2000-10-23	2001-06-28	Phosphatidyl-l-serin und phosphatidylsäure zur behandlung von depression und stresszuständen

Country Status (10)

Country	Link
US (1)	US6410522B1 (de)
EP (1)	EP1201244B1 (de)
AT (1)	ATE401898T1 (de)
CA (1)	CA2352528C (de)
DE (1)	DE60134931D1 (de)
DK (1)	DK1201244T3 (de)
ES (1)	ES2309021T3 (de)
HK (1)	HK1046237B (de)
IL (1)	IL139224A (de)
PT (1)	PT1201244E (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8178150B2 (en)	2000-02-22	2012-05-15	Suzanne Jaffe Stillman	Water containing soluble fiber
US7892586B2 (en)	2001-02-22	2011-02-22	Suzanne Jaffe Stillman	Water containing soluble fiber
US7115297B2 (en)	2000-02-22	2006-10-03	Suzanne Jaffe Stillman	Nutritionally fortified liquid composition with added value delivery systems/elements/additives
WO2001068104A1 (en) *	2000-03-16	2001-09-20	The Mclean Hospital Corporation	Compounds for the treatment of psychiatric or substance abuse disorders
IL150240A (en) *	2002-06-16	2005-07-25	Lipogen Ltd	Infant formula supplemented with phospholipids
US20050129738A1 (en) *	2002-06-16	2005-06-16	Lipogen Ltd.	Infant formula supplemented with phospholipids
US6878532B1 (en)	2003-04-28	2005-04-12	Sioux Biochemical, Inc.	Method of producing phosphatidylserine
WO2005044176A2 (en) *	2003-11-10	2005-05-19	Lipogen Ltd.	Compositions containing phosphatidic acid, methods of use thereof, methods of manufacture thereof, and articles of manufacture containing same
GB0400031D0 (en)	2004-01-03	2004-02-04	Univ Sheffield	Depression treatment
US7737128B2 (en) *	2004-06-10	2010-06-15	The Mclean Hospital Corporation	Pyrimidines, such as uridine, in treatments for patients with bipolar disorder
EP1765364A4 (de) *	2004-06-10	2010-09-22	Mclean Hospital Corp	Pyrimidine, wie z:b: cytidin, bei der behandlung von patienten mit bipolaren störungen
WO2006020703A1 (en) *	2004-08-11	2006-02-23	The Mclean Hospital Corporation	Compounds for the treatment of marihuana dependence, withdrawal, and usage
US20060275356A1 (en) *	2005-05-25	2006-12-07	Burgess James W	Pharmaceutical compositions for treating or preventing coronary artery disease
IL182372A0 (en) *	2007-04-01	2008-01-20	Enzymotec Ltd	Compositions containing phosphatidylserine in treating diabetes-associated conditions
US8546104B2 (en)	2008-08-07	2013-10-01	Lipogen Ltd.	Processes for the preparation of phosphatide salts
US8846338B2 (en) *	2008-08-07	2014-09-30	Lipogen Ltd.	Processes for the preparation of phosphatides
US20100041621A1 (en) *	2008-08-15	2010-02-18	Perry Renshaw	Methods and compositions for improving cognitive performance
US9326961B2 (en) *	2010-02-26	2016-05-03	Coape, Ltd	Diet and methods for improving learning capacity, mood and behavior in mammals
US20130064803A1 (en) *	2011-09-14	2013-03-14	Naidu Lp	BIO-REPLENISHMENT (BioRep) FOR COGNITIVE HEALTH
ES2587932T3 (es) *	2013-02-22	2016-10-27	Lipogen Ltd.	Composiciones para su uso en el alivio de los síntomas asociados con el síndrome premenstrual y el trastorno disfórico premenstrual
EP2881104A1 (de)	2013-12-05	2015-06-10	Lonza Ltd	Verwendung von Zusammensetzungen mit Phosphatidylserin und Phosphatidsäure und/oder Salzen davon zur Verringerung oder Vorbeugung von Schwitzen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4117629A1 (de) *	1991-05-29	1992-12-03	Max Planck Gesellschaft	Phospatidylserine
US5700668A (en) *	1995-12-08	1997-12-23	Italfarmaco Sud S.P.A.	Process for the industrial preparation of phosphatidylserine
IL118180A (en) *	1996-05-08	2000-12-06	Modus Biolog Membranes Ltd	Pharmaceutical compositions comprising a phosphatidic acid (PA) enriched natural phospholipid preparation and the production of such preparation

2000
- 2000-10-23 IL IL139224A patent/IL139224A/en active IP Right Grant
2001
- 2001-06-28 DE DE60134931T patent/DE60134931D1/de not_active Expired - Lifetime
- 2001-06-28 ES ES01114833T patent/ES2309021T3/es not_active Expired - Lifetime
- 2001-06-28 EP EP01114833A patent/EP1201244B1/de not_active Expired - Lifetime
- 2001-06-28 PT PT01114833T patent/PT1201244E/pt unknown
- 2001-06-28 DK DK01114833T patent/DK1201244T3/da active
- 2001-06-28 AT AT01114833T patent/ATE401898T1/de active
- 2001-07-03 US US09/897,034 patent/US6410522B1/en not_active Expired - Lifetime
- 2001-07-06 CA CA002352528A patent/CA2352528C/en not_active Expired - Fee Related
2002
- 2002-10-15 HK HK02107472.0A patent/HK1046237B/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE60134931D1 (de)	2008-09-04
EP1201244A3 (de)	2003-12-10
ES2309021T3 (es)	2008-12-16
HK1046237A1 (en)	2003-01-03
DK1201244T3 (da)	2008-11-17
HK1046237B (en)	2009-04-09
US6410522B1 (en)	2002-06-25
EP1201244B1 (de)	2008-07-23
EP1201244A2 (de)	2002-05-02
CA2352528C (en)	2005-12-06
US20020072508A1 (en)	2002-06-13
PT1201244E (pt)	2008-09-23
IL139224A (en)	2009-09-01
CA2352528A1 (en)	2002-04-23

Legal Events

Date

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Title

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2009-02-15

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Publication	Publication Date	Title
DE60134931D1 (de)	2008-09-04	Phosphatidyl-L-serin und Phosphatidylsäure zur Behandlung von Depression und Stresszuständen
CA2162232A1 (en)	1996-05-09	Cerebration improver
BR0009001A (pt)	2002-01-02	Processo para a produção de queijo, uso de um queijo, e de uma fosfolipase, e, queijo
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