ATE403145T1 - Tragbare vorrichtung mit einer sensor-array- anordnung - Google Patents

Tragbare vorrichtung mit einer sensor-array- anordnung

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Publication number
ATE403145T1
ATE403145T1 AT01905306T AT01905306T ATE403145T1 AT E403145 T1 ATE403145 T1 AT E403145T1 AT 01905306 T AT01905306 T AT 01905306T AT 01905306 T AT01905306 T AT 01905306T AT E403145 T1 ATE403145 T1 AT E403145T1
Authority
AT
Austria
Prior art keywords
sensor array
analyte
portable device
array arrangement
particle
Prior art date
Application number
AT01905306T
Other languages
English (en)
Inventor
John Mcdevitt
Eric Anslyn
Jason Shear
Dean Neikirk
Original Assignee
Univ Texas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Texas filed Critical Univ Texas
Application granted granted Critical
Publication of ATE403145T1 publication Critical patent/ATE403145T1/de

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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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Families Citing this family (523)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1080162B1 (de) * 1998-05-05 2004-03-10 Massachusetts Institute Of Technology Lichtemittierende polymere und vorrichtungen, die diese enthalten
US20050147534A1 (en) * 1998-05-05 2005-07-07 Massachusetts Institute Of Technology Emissive sensors and devices incorporating these sensors
US8198096B2 (en) * 1998-05-05 2012-06-12 Massachusetts Institute Of Technology Emissive polymers and devices incorporating these polymers
US6908770B1 (en) 1998-07-16 2005-06-21 Board Of Regents, The University Of Texas System Fluid based analysis of multiple analytes by a sensor array
JP3486557B2 (ja) * 1998-07-30 2004-01-13 宮崎沖電気株式会社 トランスファ成形装置及び半導体装置の製造方法
US6978212B1 (en) * 1999-11-01 2005-12-20 Smiths Detection Inc. System for portable sensing
US6975924B2 (en) * 1999-12-03 2005-12-13 Baxter International Inc. Method and apparatus for controlling the strategy of compounding pharmaceutical admixtures
US7316899B2 (en) * 2000-01-31 2008-01-08 The Board Of Regents Of The University Of Texas System Portable sensor array system
WO2001065905A2 (en) * 2000-03-09 2001-09-13 Koninklijke Philips Electronics N.V. A family of complex systems with shared family software architecture
WO2001072002A2 (en) 2000-03-17 2001-09-27 America Online, Inc. Shared groups rostering system
US9246975B2 (en) 2000-03-17 2016-01-26 Facebook, Inc. State change alerts mechanism
US7624172B1 (en) 2000-03-17 2009-11-24 Aol Llc State change alerts mechanism
EP2330219A3 (de) 2000-04-14 2011-11-23 Metabolon, Inc. Verfahren zur Arzneimittelentdeckung, Krankheitsbehandlung und Diagnose mithilfe eines Metaboloms
US7329489B2 (en) 2000-04-14 2008-02-12 Matabolon, Inc. Methods for drug discovery, disease treatment, and diagnosis using metabolomics
SE0001790D0 (sv) * 2000-05-12 2000-05-12 Aamic Ab Hydrophobic barrier
EP1311848A2 (de) * 2000-07-07 2003-05-21 Bristol-Myers Squibb Company Hochdurchfluss-screening zur entdeckung von arzneimitteln sowie dafür geeignete electrophysiologie-vorrichtung
RU2278612C2 (ru) * 2000-07-14 2006-06-27 Лайфскен, Инк. Иммуносенсор
US7049579B2 (en) * 2000-07-26 2006-05-23 The Regents Of The University Of California Manipulation of live cells and inorganic objects with optical micro beam arrays
GB2366011B (en) * 2000-08-14 2004-10-13 Biotrace Ltd Data processing system
US6778724B2 (en) * 2000-11-28 2004-08-17 The Regents Of The University Of California Optical switching and sorting of biological samples and microparticles transported in a micro-fluidic device, including integrated bio-chip devices
WO2002044689A2 (en) * 2000-11-28 2002-06-06 The Regents Of The University Of California Storing microparticles in optical switch which is transported by micro-fluidic device
EP1373874A4 (de) * 2001-01-31 2004-03-31 Univ Texas Verfahren und vorrichtung zum eingrenzen von materialien in einem mikrobearbeiteten chemischen sensorarray
US7425453B1 (en) * 2001-03-14 2008-09-16 The United States Of America As Represented By The Secretary Of The Navy Integrated circuit porphyrin-based optical Fabry-Perot chemical sensor
DE10117275B4 (de) * 2001-04-06 2005-02-24 Hte Ag The High Throughput Experimentation Company Vorrichtung zur Archivierung und Analyse von Materialien
US20050032204A1 (en) * 2001-04-10 2005-02-10 Bioprocessors Corp. Microreactor architecture and methods
US20040132166A1 (en) * 2001-04-10 2004-07-08 Bioprocessors Corp. Determination and/or control of reactor environmental conditions
US20040058407A1 (en) * 2001-04-10 2004-03-25 Miller Scott E. Reactor systems having a light-interacting component
DE10123259A1 (de) * 2001-05-12 2002-11-21 Eppendorf Ag Mikrofluidisches Speicher- und/oder Dosierbauteil
EP1277438A1 (de) * 2001-07-10 2003-01-22 Agilent Technologies, Inc. (a Delaware corporation) Pflegeplatz Diagnose und/oder Analyse System
US20040146917A1 (en) * 2001-08-03 2004-07-29 Nanosphere, Inc. Nanoparticle imaging system and method
CA2455118C (en) * 2001-08-03 2012-01-17 Nanosphere, Inc. Nanoparticle imaging system and method
US7253003B2 (en) * 2001-10-19 2007-08-07 Wisconsin Alumni Research Foundation Method for monitoring the environment within a microfluidic device
AU2002335101B2 (en) * 2001-10-22 2008-06-26 Mcneil-Ppc, Inc. Interactive product selection system
US7304259B2 (en) 2001-11-01 2007-12-04 Siemens Energy & Automation, Inc. Mail processing system with multilevel contaminant detection and sterilization
EP1452986A4 (de) * 2001-11-05 2006-08-16 Daikin Ind Ltd Sanitär-messystem
US7584240B2 (en) 2001-11-07 2009-09-01 Genvault Corporation Automated biological sample archive for storage, retrieval and analysis of large numbers of samples for remote clients
US20030087455A1 (en) * 2001-11-07 2003-05-08 Eggers Mitchell D Sample carrier system
US6989891B2 (en) * 2001-11-08 2006-01-24 Optiscan Biomedical Corporation Device and method for in vitro determination of analyte concentrations within body fluids
US7232691B2 (en) * 2001-11-27 2007-06-19 Los Alamos National Security, Llc Bioassay and biomolecular identification, sorting, and collection methods using magnetic microspheres
US7462325B2 (en) * 2001-11-30 2008-12-09 Nomadics, Inc. Luminescent polymer particles
US20030113730A1 (en) * 2001-12-18 2003-06-19 Daquino Lawrence J. Pulse jet print head having multiple printhead dies and methods for use in the manufacture of biopolymeric arrays
CN101299027B (zh) * 2001-12-27 2011-08-10 爱科来株式会社 浓度测定方法
US7169107B2 (en) * 2002-01-25 2007-01-30 Karen Jersey-Willuhn Conductivity reconstruction based on inverse finite element measurements in a tissue monitoring system
JP3721334B2 (ja) * 2002-02-01 2005-11-30 富士写真フイルム株式会社 リセプター・リガンド会合反応方法およびそれに用いるリアクタ
US20080172026A1 (en) 2006-10-17 2008-07-17 Blomquist Michael L Insulin pump having a suspension bolus
US7892420B2 (en) * 2004-08-03 2011-02-22 Dornoch Medical Systems, Inc. High volume liquid waste collection and disposal system
US20060134713A1 (en) 2002-03-21 2006-06-22 Lifescan, Inc. Biosensor apparatus and methods of use
US7057724B1 (en) * 2002-03-21 2006-06-06 Institute Of Critical Care Medicine Particulate info to field units
US20120078075A1 (en) * 2002-04-04 2012-03-29 Maynard John D Determination of a measure of a glycation end-product or disease state using tissue fluorescence in combination with one or more other tests
US20050026134A1 (en) * 2002-04-10 2005-02-03 Bioprocessors Corp. Systems and methods for control of pH and other reactor environment conditions
US9943847B2 (en) 2002-04-17 2018-04-17 Cytonome/St, Llc Microfluidic system including a bubble valve for regulating fluid flow through a microchannel
US8257967B2 (en) * 2002-04-26 2012-09-04 Board Of Regents, The University Of Texas System Method and system for the detection of cardiac risk factors
US20050055242A1 (en) * 2002-04-30 2005-03-10 Bryan Bello System and method for medical data tracking, analysis and reporting for healthcare system
US20030215369A1 (en) * 2002-05-17 2003-11-20 Eggers Mitchell D. Sample carrier receiver
EP1364613A1 (de) * 2002-05-23 2003-11-26 FESTO AG & Co Vorrichtung zur Gesundheitsüberprüfung und -überwachung
US7776195B2 (en) * 2002-05-28 2010-08-17 Autogenomics, Inc. Integrated sample processing platform
US7332273B2 (en) 2002-06-20 2008-02-19 Affymetrix, Inc. Antireflective coatings for high-resolution photolithographic synthesis of DNA arrays
US20070275411A1 (en) 2006-05-25 2007-11-29 Mcgall Glenn H Silane mixtures
US20030003587A1 (en) * 2002-06-28 2003-01-02 Murray George M Molecularly imprinted polymer based sensors for the detection of narcotics
AU2003269913A1 (en) * 2002-07-15 2004-02-02 Massachusetts Institute Of Technology Emissive, high charge transport polymers
AU2003256742A1 (en) * 2002-07-24 2004-02-09 Board Of Regents, The University Of Texas System Capture and detection of microbes by membrane methods
US7867754B1 (en) 2002-08-01 2011-01-11 Purdue Research Foundation Microarrays for analyte detection
US7455770B2 (en) * 2002-09-09 2008-11-25 Cytonome, Inc. Implementation of microfluidic components in a microfluidic system
EP1539921B1 (de) * 2002-09-16 2007-11-21 Pan-Biotech GmbH Einrichtung zur kultivierung von zellen, insbesondere menschlicher oder tierischer zellen
ES2295465T3 (es) * 2002-09-16 2008-04-16 Pan-Biotech Gmbh Procedimiento para el cultivo de celulas, en especial de celulas humanas o de animales.
DK1539925T3 (da) * 2002-09-16 2008-02-18 Pan Biotech Gmbh Cellekulturkammer til et cellekultursystem
ITTO20020808A1 (it) * 2002-09-17 2004-03-18 St Microelectronics Srl Dispositivo integrato di analisi del dna.
US7964390B2 (en) * 2002-10-11 2011-06-21 Case Western Reserve University Sensor system
US7122384B2 (en) * 2002-11-06 2006-10-17 E. I. Du Pont De Nemours And Company Resonant light scattering microparticle methods
US7899862B2 (en) 2002-11-18 2011-03-01 Aol Inc. Dynamic identification of other users to an online user
US7590696B1 (en) 2002-11-18 2009-09-15 Aol Llc Enhanced buddy list using mobile device identifiers
US7428580B2 (en) 2003-11-26 2008-09-23 Aol Llc Electronic message forwarding
CA2506585A1 (en) 2002-11-18 2004-06-03 Valerie Kucharewski People lists
US8965964B1 (en) 2002-11-18 2015-02-24 Facebook, Inc. Managing forwarded electronic messages
US7640306B2 (en) 2002-11-18 2009-12-29 Aol Llc Reconfiguring an electronic message to effect an enhanced notification
US8005919B2 (en) 2002-11-18 2011-08-23 Aol Inc. Host-based intelligent results related to a character stream
US8122137B2 (en) 2002-11-18 2012-02-21 Aol Inc. Dynamic location of a subordinate user
US8701014B1 (en) 2002-11-18 2014-04-15 Facebook, Inc. Account linking
WO2005001411A2 (en) * 2002-11-20 2005-01-06 Laser Light Technologies, Inc. An online flow through microchip for detecting hazardous chemical and biological agents in drinking water
US7718442B2 (en) * 2002-11-22 2010-05-18 Genvault Corporation Sealed sample storage element system and method
US7062385B2 (en) * 2002-11-25 2006-06-13 Tufts University Intelligent electro-optical nucleic acid-based sensor array and method for detecting volatile compounds in ambient air
JP2006507507A (ja) * 2002-11-25 2006-03-02 タフツ ユニバーシティー 核酸に基づく電気光学的センサーアレイおよび分析物を検出するための方法
US20040106114A1 (en) * 2002-12-02 2004-06-03 Eastman Kodak Company Simplified detection process for colored bead random microarrays
US20040121337A1 (en) * 2002-12-19 2004-06-24 Nomadics, Inc. Luminescent polymers and methods of use thereof
WO2004083806A2 (en) * 2003-01-22 2004-09-30 University Of South Florida Autonomous genosensor apparatus and methods for use
US7125727B2 (en) * 2003-01-29 2006-10-24 Protedyne Corporation Sample handling tool with piezoelectric actuator
EP1590669B1 (de) * 2003-02-05 2009-11-25 The General Hospital Corporation System auf mikrochipbasis zur hiv-diagnostik
WO2004072613A2 (en) * 2003-02-07 2004-08-26 Board Of Regents, The University Of Texas System Multi-shell microspheres with integrated chomatographic and detection layers for use in array sensors
US20040162844A1 (en) * 2003-02-13 2004-08-19 J. J. Keller & Associates, Inc. Driver management system and method
US7613776B1 (en) 2003-03-26 2009-11-03 Aol Llc Identifying and using identities deemed to be known to a user
WO2004097371A2 (en) * 2003-04-25 2004-11-11 Board Of Regents, The University Of Texas System System and method for the detection of analytes
US20100075858A1 (en) * 2003-04-29 2010-03-25 Genvault Corporation Biological bar code
US7651850B2 (en) 2003-05-16 2010-01-26 Board Of Regents, The University Of Texas System Image and part recognition technology
US9317922B2 (en) 2003-05-16 2016-04-19 Board Of Regents The University Of Texas System Image and part recognition technology
US20040241880A1 (en) * 2003-05-30 2004-12-02 Leproust Eric M. Ligand array assays having reduced fluorescent dye degradation and compositions for practicing the same
US7860727B2 (en) * 2003-07-17 2010-12-28 Ventana Medical Systems, Inc. Laboratory instrumentation information management and control network
US8719053B2 (en) * 2003-07-17 2014-05-06 Ventana Medical Systems, Inc. Laboratory instrumentation information management and control network
US7653693B2 (en) 2003-09-05 2010-01-26 Aol Llc Method and system for capturing instant messages
US7298478B2 (en) 2003-08-14 2007-11-20 Cytonome, Inc. Optical detector for a particle sorting system
KR20140134338A (ko) * 2003-09-11 2014-11-21 테라노스, 인코포레이티드 피분석물의 모니터링 및 약물 전달을 위한 의료 기기
US7198855B2 (en) * 2003-09-12 2007-04-03 Becton, Dickinson And Company Methods of surface modification of a flexible substrate to enhance cell adhesion
WO2005031163A1 (en) * 2003-09-25 2005-04-07 Cytonome, Inc. Implementation of microfluidic components in a microfluidic system
US7524464B2 (en) 2003-09-26 2009-04-28 Ahn Chong H Smart disposable plastic lab-on-a-chip for point-of-care testing
JP4334969B2 (ja) * 2003-10-02 2009-09-30 パナソニック株式会社 血液成分分析用センサ
US7121647B2 (en) * 2003-10-03 2006-10-17 Lexmark International, Inc. Method of applying an encapsulant material to an ink jet printhead
US7159974B2 (en) * 2003-10-06 2007-01-09 Lexmark International, Inc. Semipermeable membrane for an ink reservoir and method of attaching the same
US7582485B2 (en) * 2003-10-16 2009-09-01 Kimberly-Clark Worldride, Inc. Method and device for detecting ammonia odors and helicobacter pylori urease infection
US20100104473A1 (en) * 2003-11-06 2010-04-29 Kirollos Salama Kirollos Air sampling system and method for calibration
US20050100483A1 (en) * 2003-11-12 2005-05-12 Cytyc Corporation Specimen filter container having data storage
EP2264191A1 (de) * 2003-11-21 2010-12-22 ANP Technologies, Inc. Asymmetrisch verzweigte Polymerkonjugate und Mikroarray-Tests
US7382004B2 (en) * 2003-11-25 2008-06-03 Sensor Electronic Technology, Inc. Semiconductor sensing device
EP1695082A2 (de) 2003-12-11 2006-08-30 Board of Regents, The University of Texas System Verfahren und vorrichtung für die analyse von speichel unter verwendung eines sensorarrays
US7122799B2 (en) * 2003-12-18 2006-10-17 Palo Alto Research Center Incorporated LED or laser enabled real-time PCR system and spectrophotometer
US20080044844A1 (en) * 2004-01-27 2008-02-21 Shimshon Belkin Populations Of Cells And Devices And Systems Including Same
US7276389B2 (en) * 2004-02-25 2007-10-02 Samsung Electronics Co., Ltd. Article comprising metal oxide nanostructures and method for fabricating such nanostructures
US7465210B2 (en) * 2004-02-25 2008-12-16 The Regents Of The University Of California Method of fabricating carbide and nitride nano electron emitters
US8105849B2 (en) 2004-02-27 2012-01-31 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements
US8101431B2 (en) * 2004-02-27 2012-01-24 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems
US20060257991A1 (en) * 2004-02-27 2006-11-16 Mcdevitt John T Integration of fluids and reagents into self-contained cartridges containing particle-based sensor elements and membrane-based sensor elements
CN1690120A (zh) * 2004-03-01 2005-11-02 三菱瓦斯化学株式会社 具有高减震能力的树脂组合物
US7402425B2 (en) * 2004-03-02 2008-07-22 The Charles Stark Draper Laboratory, Inc. Stress-based electrostatic monitoring of chemical reactions and binding
WO2005091927A2 (en) * 2004-03-06 2005-10-06 Ryan O'donnell Methods and devices for monitoring the distance between members of a group
TWI233637B (en) * 2004-03-17 2005-06-01 Promos Technologies Inc Method of correcting lithography process and method of forming overlay mark
US7187286B2 (en) * 2004-03-19 2007-03-06 Applera Corporation Methods and systems for using RFID in biological field
US20050216291A1 (en) * 2004-06-16 2005-09-29 Shaheen Elias A Complete mold system
US7230520B2 (en) * 2004-05-03 2007-06-12 Dell Products L.P. Method and apparatus for RF access to system ID and fault information
US7887750B2 (en) * 2004-05-05 2011-02-15 Bayer Healthcare Llc Analytical systems, devices, and cartridges therefor
EP1758937B1 (de) 2004-05-24 2009-09-02 Genvault Corporation Stabile lagerung von protein und stabile lagerung von nukleinsäure in wiedergewinnbarer form
WO2005120691A1 (en) * 2004-06-07 2005-12-22 Bioprocessors Corp. Reactor mixing
WO2005121310A2 (en) * 2004-06-07 2005-12-22 Bioprocessors Corp. Creation of shear in a reactor
US20050271560A1 (en) * 2004-06-07 2005-12-08 Bioprocessors Corp. Gas control in a reactor
US7910531B2 (en) * 2004-06-17 2011-03-22 C2C Technologies Llc Composition and method for producing colored bubbles
US20050287536A1 (en) * 2004-06-24 2005-12-29 Douglas Kozlay Disposable, multi-use, DNA sample collection disk apparatus for field biohazard testing, DNA testing, and personal authentication
AU2005259981B2 (en) 2004-06-29 2012-01-12 Dako Denmark A/S Method of pre-treatment and staining of and support device for a biological sample
US7404613B2 (en) * 2004-06-30 2008-07-29 Lexmark International, Inc. Inkjet print cartridge having an adhesive with improved dimensional control
US20060008919A1 (en) * 2004-07-09 2006-01-12 Boay Yoke P Method and apparatus for detecting gas/radiation that employs color change detection mechanism
WO2006034081A2 (en) * 2004-09-17 2006-03-30 Massachusetts Institute Of Technology Polymers for analyte detection
CA2583406A1 (en) * 2004-09-20 2007-01-04 Boston Microfluidics Microfluidic device for detecting soluble molecules
US20060067650A1 (en) * 2004-09-27 2006-03-30 Clarence Chui Method of making a reflective display device using thin film transistor production techniques
EP1812603A4 (de) * 2004-10-21 2010-12-22 Pharma Diagnostics N V Stabiles metall/leitendes polymer-verbundkolloide und verfahren zur herstellung und verwendung davon
US7361315B2 (en) * 2004-10-26 2008-04-22 Konica Minolta Medical & Graphic, Inc. Micro-reactor for biological substance inspection and biological substance inspection device
KR20070083810A (ko) * 2004-10-28 2007-08-24 가부시키가이샤 심스 질병 진단 시스템
DE102004056735A1 (de) * 2004-11-09 2006-07-20 Clondiag Chip Technologies Gmbh Vorrichtung für die Durchführung und Analyse von Mikroarray-Experimenten
ES2573847T3 (es) * 2004-11-17 2016-06-10 Gt Acquisition Sub, Inc. Sistema de seguimiento de animales por radio frecuencia
US20070103314A1 (en) * 2004-11-17 2007-05-10 Geissler Randolph K Radio frequency animal tracking system
HU226650B1 (hu) * 2004-11-30 2009-05-28 Vils Ag H Rendszer anyagtárolásra szolgáló teret határoló, a belsõ felén bevonattal ellátott fal vagy/és a bevonat meghibásodásának észlelésére, valamint eljárás a rendszer elõállítására
US9260693B2 (en) 2004-12-03 2016-02-16 Cytonome/St, Llc Actuation of parallel microfluidic arrays
CA2588753C (en) 2004-12-03 2014-02-18 Cytonome, Inc. Unitary cartridge for particle processing
GB2420850A (en) * 2004-12-03 2006-06-07 Orion Diagnostica Oy Particle based binding assay
US7879764B2 (en) * 2004-12-28 2011-02-01 Intel Corporation Electrically active combinatorial chemical (EACC) chip for biochemical analyte detection
US20060141421A1 (en) * 2004-12-28 2006-06-29 Kimberly-Clark Worldwide, Inc. System and method for detecting substances related to oral health
US9182480B2 (en) * 2005-01-28 2015-11-10 Hewlett-Packard Development Company, L.P. Information technology (IT) equipment positioning system
US7910356B2 (en) 2005-02-01 2011-03-22 Purdue Research Foundation Multiplexed biological analyzer planar array apparatus and methods
US20070023643A1 (en) 2005-02-01 2007-02-01 Nolte David D Differentially encoded biological analyzer planar array apparatus and methods
US7405831B2 (en) 2005-02-01 2008-07-29 Purdue Research Foundation Laser scanning interferometric surface metrology
US8251907B2 (en) 2005-02-14 2012-08-28 Optiscan Biomedical Corporation System and method for determining a treatment dose for a patient
US8936755B2 (en) 2005-03-02 2015-01-20 Optiscan Biomedical Corporation Bodily fluid composition analyzer with disposable cassette
US7722537B2 (en) * 2005-02-14 2010-05-25 Optiscan Biomedical Corp. Method and apparatus for detection of multiple analytes
US20060194325A1 (en) 2005-02-14 2006-08-31 Gable Jennifer H Fluid handling cassette with a fluid control interface
US20060183261A1 (en) * 2005-02-15 2006-08-17 Dudenhoefer Christie L Method of forming a biological sensor
US7775370B2 (en) * 2005-03-21 2010-08-17 Utah State University Particle sorting by fluidic vectoring
WO2008097261A2 (en) * 2006-07-13 2008-08-14 The Trustees Of The University Of Pennsylvania Single walled carbon nanotubes with functionally adsorbed biopolymers for use as chemical sensors
US20060257439A1 (en) * 2005-03-29 2006-11-16 Sabnis Ram W Cleansing compositions with color changing indicator
US20060222601A1 (en) * 2005-03-29 2006-10-05 Sabnis Ram W Oral care compositions with color changing indicator
US20060236470A1 (en) * 2005-03-29 2006-10-26 Sabnis Ram W Novelty compositions with color changing indicator
WO2006110347A2 (en) * 2005-03-29 2006-10-19 The Trustees Of The University Of Pennsylvania Single walled carbon nanotubes functionally adsorbed to biopolymers for use as chemical sensors
US20060222675A1 (en) * 2005-03-29 2006-10-05 Sabnis Ram W Personal care compositions with color changing indicator
US7682816B2 (en) * 2005-04-07 2010-03-23 454 Life Sciences Corporation Thin film coated microwell arrays and methods of using same
CA2507323A1 (en) * 2005-05-13 2006-11-13 Chromedx Inc. Diagnostic whole blood and plasma apparatus
CA2517299A1 (en) * 2005-08-26 2007-02-26 Chromedx Inc. Hollow needle assembly
US20100245803A1 (en) * 2005-04-12 2010-09-30 Chromedx Inc. Blood sample holder for spectroscopic analysis
US8206650B2 (en) * 2005-04-12 2012-06-26 Chromedx Inc. Joint-diagnostic spectroscopic and biosensor meter
US7740804B2 (en) * 2005-04-12 2010-06-22 Chromedx Inc. Spectroscopic sample holder
EP1717585B1 (de) * 2005-04-28 2013-01-16 FUJIFILM Corporation Mikrochip und Analyseverfahren unter Verwendung desselben
ES2820430T3 (es) 2005-05-09 2021-04-21 Labrador Diagnostics Llc Sistemas de fluidos para centros de atención y usos de los mismos
JP2006322841A (ja) * 2005-05-19 2006-11-30 Shimadzu Corp 分光測定方法及び分光光度計
US8076143B2 (en) * 2005-05-25 2011-12-13 Westfall Geofrey J Method for determining quality of milk and presence of mastitis
US20060267731A1 (en) * 2005-05-31 2006-11-30 Chen Thomas C H System and apparatus of Internet-linked RFID sensor network for object identifying, sensing, monitoring, tracking and networking
US8377398B2 (en) 2005-05-31 2013-02-19 The Board Of Regents Of The University Of Texas System Methods and compositions related to determination and use of white blood cell counts
CA2610875A1 (en) 2005-06-06 2006-12-14 Decision Biomarkers, Inc. Assays based on liquid flow over arrays
US7456960B2 (en) * 2005-06-06 2008-11-25 Particle Measuring Systems, Inc. Particle counter with improved image sensor array
US7749531B2 (en) * 2005-06-08 2010-07-06 Indicator Systems International Apparatus and method for detecting bacterial growth beneath a wound dressing
US7681436B2 (en) * 2005-06-22 2010-03-23 Hitek Aqua Systems, Llc In-situ water analysis method and system
USD537913S1 (en) 2005-06-22 2007-03-06 Hitek Aqua Systems, Llc Floating housing
EP2508867A1 (de) 2005-06-24 2012-10-10 Board Of Regents, The University Of Texas System Systeme und Verfahren einschliesslich in sich geschlossener Kassetten mit Nachweissystemen und Flüssigkeitszufuhrsystemen
US7409853B2 (en) * 2005-06-30 2008-08-12 Hitek Aqua Systems, Llc Floatable housing for in situ water monitoring system
US20090215646A1 (en) * 2005-07-01 2009-08-27 The Board Of Regents Of The University Of Texas Sy System and method of analyte detection using differential receptors
US20070010400A1 (en) * 2005-07-06 2007-01-11 Sabnis Ram W Use of color changing indicators in consumer products
US8287818B2 (en) * 2005-07-18 2012-10-16 Kantrowitz Allen B Modular hospital cart
JP4764969B2 (ja) * 2005-07-25 2011-09-07 ローム株式会社 マイクロチップ測定装置
US7791728B2 (en) * 2005-08-11 2010-09-07 Hewlett-Packard Development Company, L.P. System for optically analyzing a substance with a selected single-wavelength
US20080280290A1 (en) * 2005-08-19 2008-11-13 Dawson Elliott P Method and Device for the Collection and Isolation of Nucleic Acid
US9486274B2 (en) 2005-09-07 2016-11-08 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US10548659B2 (en) 2006-01-17 2020-02-04 Ulthera, Inc. High pressure pre-burst for improved fluid delivery
US9358033B2 (en) * 2005-09-07 2016-06-07 Ulthera, Inc. Fluid-jet dissection system and method for reducing the appearance of cellulite
US9011473B2 (en) 2005-09-07 2015-04-21 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US8518069B2 (en) 2005-09-07 2013-08-27 Cabochon Aesthetics, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US7556776B2 (en) * 2005-09-08 2009-07-07 President And Fellows Of Harvard College Microfluidic manipulation of fluids and reactions
US7544330B2 (en) * 2005-09-28 2009-06-09 Idexx Laboratories, Inc. Microplate sample tracking system
US9561001B2 (en) 2005-10-06 2017-02-07 Optiscan Biomedical Corporation Fluid handling cassette system for body fluid analyzer
US20070141597A1 (en) * 2005-10-25 2007-06-21 Harmon H J Biomimetic Biodetector of Toxins, Viruses, Bacteria, and Biological Factors
CA2631248C (en) * 2005-11-28 2016-01-12 Pacific Biosciences Of California, Inc. Uniform surfaces for hybrid material substrates and methods for making and using same
US20080241000A1 (en) * 2007-03-27 2008-10-02 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Systems for pathogen detection
US20080241935A1 (en) * 2007-03-27 2008-10-02 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods for pathogen detection
US7885793B2 (en) 2007-05-22 2011-02-08 International Business Machines Corporation Method and system for developing a conceptual model to facilitate generating a business-aligned information technology solution
US9248317B2 (en) 2005-12-02 2016-02-02 Ulthera, Inc. Devices and methods for selectively lysing cells
US7405417B2 (en) * 2005-12-20 2008-07-29 Asml Netherlands B.V. Lithographic apparatus having a monitoring device for detecting contamination
US7649359B2 (en) * 2005-12-27 2010-01-19 The Curators Of The University Of Missouri Electrostatic thin film chemical and biological sensor
FR2895667B3 (fr) * 2006-01-05 2008-04-04 Rene Vinci Detecteur de fecondite pour mammiferes
US20070158804A1 (en) * 2006-01-10 2007-07-12 Semiconductor Energy Laboratory Co., Ltd. Semiconductor device, manufacturing method of semiconductor device, and RFID tag
DE102006002093B4 (de) * 2006-01-17 2010-11-25 Airbus Deutschland Gmbh Vorrichtung zur Erfassung von Konturabweichungen eines flexiblen Bauteils unter Berücksichtigung des Bauteileigengewichts sowie Verfahren
US20080175963A1 (en) * 2006-01-26 2008-07-24 Bunn-O-Matic Corporation Beverage Freshness Detecting and Indicating Systems
US7652268B2 (en) * 2006-01-31 2010-01-26 Jp Laboratories, Inc General purpose, high accuracy dosimeter reader
US11237171B2 (en) 2006-02-21 2022-02-01 Trustees Of Tufts College Methods and arrays for target analyte detection and determination of target analyte concentration in solution
US8460879B2 (en) 2006-02-21 2013-06-11 The Trustees Of Tufts College Methods and arrays for target analyte detection and determination of target analyte concentration in solution
US8064722B1 (en) * 2006-03-07 2011-11-22 The United States Of America As Represented By The Secretary Of The Navy Method and system for analyzing signal-vector data for pattern recognition from first order sensors
US11287421B2 (en) 2006-03-24 2022-03-29 Labrador Diagnostics Llc Systems and methods of sample processing and fluid control in a fluidic system
US8741230B2 (en) * 2006-03-24 2014-06-03 Theranos, Inc. Systems and methods of sample processing and fluid control in a fluidic system
WO2007110810A1 (en) * 2006-03-28 2007-10-04 Koninklijke Philips Electronics N.V. Integrated device having an array of photodetectors and an array of sample sites
US20100120132A1 (en) * 2006-03-31 2010-05-13 Intel Corporation Bioassays by direct optical detection of nanoparticles
JP2009533676A (ja) * 2006-04-13 2009-09-17 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー 手持ち式ガス検知器およびガス検知方法
US7734131B2 (en) * 2006-04-18 2010-06-08 Xerox Corporation Fabry-Perot tunable filter using a bonded pair of transparent substrates
US8007999B2 (en) 2006-05-10 2011-08-30 Theranos, Inc. Real-time detection of influenza virus
EP2021491A4 (de) 2006-05-10 2010-02-24 Univ Texas Nachweis von tumorbiomarkern bei mundkrebs
US8137626B2 (en) 2006-05-19 2012-03-20 California Institute Of Technology Fluorescence detector, filter device and related methods
EP1870027A1 (de) * 2006-06-21 2007-12-26 Trace Analytics GmbH Vorrichtungen und Verfahren zum Nachweisen eines Analyten
US7549349B2 (en) * 2006-06-22 2009-06-23 Evogen, Inc. Sample cartridge for air-sampling device
EP2041556A1 (de) * 2006-06-28 2009-04-01 RGB Technologies AB Sensorkit und system zum nachweis eines analyten in einer testumgebung
JP4145938B2 (ja) * 2006-06-28 2008-09-03 株式会社オンチップ・バイオテクノロジーズ 細胞分離チップおよびこれを使用した細胞培養方法
US20080004504A1 (en) * 2006-06-30 2008-01-03 Kimmo Uutela System for detecting allergic reactions resulting from a chemical substance given to a patient
US20080026373A1 (en) * 2006-07-26 2008-01-31 Rodionova Natalia A Assays Based On Light Emission From Analyte Complexes Within A Cassette
ES2688281T3 (es) 2006-07-28 2018-10-31 Diagnostics For The Real World, Ltd Dispositivo, sistema y método para procesar una muestra
US8158437B2 (en) * 2006-08-04 2012-04-17 Massachusetts Institute Of Technology Luminescent detection of hydrazine and hydrazine derivatives
WO2008033575A2 (en) 2006-09-15 2008-03-20 Metabolon, Inc. Methods of identifying biochemical pathways
US8187541B2 (en) * 2006-09-18 2012-05-29 California Institute Of Technology Apparatus for detecting target molecules and related methods
US7890463B2 (en) * 2006-09-28 2011-02-15 Xeround Systems Ltd. Apparatus and method for a distributed storage global database
US8283423B2 (en) 2006-09-29 2012-10-09 Massachusetts Institute Of Technology Polymer synthetic technique
US8802447B2 (en) * 2006-10-05 2014-08-12 Massachusetts Institute Of Technology Emissive compositions with internal standard and related techniques
US20080161204A1 (en) * 2006-10-06 2008-07-03 Mo-Huang Li Microwell array for parallel synthesis of chain molecules
US20080084559A1 (en) * 2006-10-10 2008-04-10 C Technologies, Inc. Microvolume sampling device
US20090215189A1 (en) 2006-10-27 2009-08-27 Massachusetts Institute Of Technology Sensor of species including toxins and chemical warfare agents
US20080113391A1 (en) 2006-11-14 2008-05-15 Ian Gibbons Detection and quantification of analytes in bodily fluids
US8701469B2 (en) 2006-11-21 2014-04-22 Cornell University Flexible substrate sensor system for environmental and infrastructure monitoring
US7522282B2 (en) 2006-11-30 2009-04-21 Purdue Research Foundation Molecular interferometric imaging process and apparatus
US9273345B2 (en) * 2006-12-28 2016-03-01 Conceptual Mindworks, Inc. Methods and compositions for processes of rapid selection and production of nucleic acid aptamers
US8323982B2 (en) 2007-01-11 2012-12-04 Valencell, Inc. Photoelectrocatalytic fluid analyte sensors and methods of fabricating and using same
WO2008089282A2 (en) * 2007-01-16 2008-07-24 Silver James H Sensors for detecting subtances indicative of stroke, ischemia, infection or inflammation
US9945789B2 (en) 2007-01-16 2018-04-17 Alverix, Inc. Multiple analyte detection systems and methods of detecting multiple analytes
WO2008089495A2 (en) 2007-01-19 2008-07-24 Purdue Research Foundation System with extended range of molecular sensing through integrated multi-modal data acquisition
HUE044597T2 (hu) * 2007-01-21 2019-11-28 Gt Acquisition Sub Inc Állatkezelõ rendszer és megfelelõ eljárás rádiós állatcímkével és járulékos adó-vevõvel/adó-vevõkkel
US20080181821A1 (en) * 2007-01-29 2008-07-31 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Microfluidic chips for allergen detection
US20080181816A1 (en) * 2007-01-29 2008-07-31 Searete Llc, A Limited Liability Corporation Systems for allergen detection
US10001496B2 (en) * 2007-01-29 2018-06-19 Gearbox, Llc Systems for allergen detection
US20080180259A1 (en) * 2007-01-29 2008-07-31 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Devices for allergen detection
US8617903B2 (en) * 2007-01-29 2013-12-31 The Invention Science Fund I, Llc Methods for allergen detection
US8168140B2 (en) * 2007-01-31 2012-05-01 Agilent Technologies, Inc. Microfluidic apparatuses with nanochannels
US7787126B2 (en) 2007-03-26 2010-08-31 Purdue Research Foundation Method and apparatus for conjugate quadrature interferometric detection of an immunoassay
US20090215157A1 (en) * 2007-03-27 2009-08-27 Searete Llc Methods for pathogen detection
US20080243865A1 (en) * 2007-03-28 2008-10-02 Oracle International Corporation Maintaining global state of distributed transaction managed by an external transaction manager for clustered database systems
WO2008131039A2 (en) * 2007-04-16 2008-10-30 Board Of Regents, The University Of Texas System Cardibioindex/cardibioscore and utility of salivary proteome in cardiovascular diagnostics
WO2008134466A1 (en) * 2007-04-25 2008-11-06 3M Innovative Properties Company Chemical component and processing device assembly
CN101668590A (zh) * 2007-04-25 2010-03-10 3M创新有限公司 化学组分和处理装置组件
US8597190B2 (en) 2007-05-18 2013-12-03 Optiscan Biomedical Corporation Monitoring systems and methods with fast initialization
KR100903969B1 (ko) * 2007-06-12 2009-06-25 삼성전자주식회사 마이크로 어레이, 마이크로 어레이용 기판 및 이들의 제조방법
WO2008157325A2 (en) * 2007-06-15 2008-12-24 Charles Stark Draper Laboratory, Inc. Devices, systems, and methods for measuring glucose
CA2691197C (en) 2007-06-21 2013-03-12 Gen-Probe Incorporated Instrument and receptacles for use in performing processes
USD591012S1 (en) 2007-06-25 2009-04-21 Destron Fearing Corporation Animal ear tag
US8921121B2 (en) * 2007-06-29 2014-12-30 The Trustees Of Columbia University In The City Of New York Methods, devices, and systems for chemiluminescence-based microfluidic cell counting
WO2009006456A1 (en) * 2007-06-29 2009-01-08 The Trustees Of Columbia University Microfluidic device for counting biological particles
US8790877B2 (en) * 2007-07-12 2014-07-29 The United States Of America As Represented By The Secretary Of The Air Force Using DNA aptamers and quantum dots for the detection of proteins or other targets
US8158430B1 (en) 2007-08-06 2012-04-17 Theranos, Inc. Systems and methods of fluidic sample processing
WO2009024773A1 (en) 2007-08-17 2009-02-26 Diagnostics For The Real World, Ltd Device, system and method for processing a sample
ES2556627T3 (es) 2007-08-30 2016-01-19 Trustees Of Tufts College Métodos para determinar la concentración de un analito en solución
US8318107B2 (en) * 2007-09-05 2012-11-27 Biosense Technologies, Inc. Apparatus and method for specimen suitability testing
EP2237687B1 (de) * 2007-09-06 2016-08-03 Fredrica V. Coates Kleinkindwickeltuch mit körperpolsterung
WO2009033370A1 (en) * 2007-09-10 2009-03-19 The University Of Hong Kong Electronic tongue sensor
GB0719373D0 (en) * 2007-10-04 2007-11-14 Univ Cranfield Optical multisensor
US20090093738A1 (en) * 2007-10-09 2009-04-09 Cabochon Aesthetics, Inc. Device and method for monitoring a treatment area
US8439940B2 (en) 2010-12-22 2013-05-14 Cabochon Aesthetics, Inc. Dissection handpiece with aspiration means for reducing the appearance of cellulite
US7978079B2 (en) * 2007-10-12 2011-07-12 Destron Fearing Corporation Electronic tag
US20090148342A1 (en) * 2007-10-29 2009-06-11 Bromberg Steven E Hypochlorite Technology
US20100209927A1 (en) * 2007-11-06 2010-08-19 Menon Vinod P Processing device tablet
US8637271B2 (en) * 2007-11-08 2014-01-28 Indicator Systems International, Inc. Polymeric indicators for detecting the presence of metabolic byproducts from microorganisms
WO2009079156A2 (en) * 2007-11-20 2009-06-25 3M Innovative Properties Company Detection devices and methods
US20140236351A1 (en) * 2007-11-29 2014-08-21 Searete Llc Programmed Dispensing of Consumable Compositions
CN101925809B (zh) 2007-12-04 2013-03-27 粒子监测系统有限公司 用于粒子检测的二维光学成像方法和系统
US7897410B2 (en) * 2007-12-18 2011-03-01 Texas Instruments Incorporated Close proximity scanning surface contamination analyzer
EP2227537A4 (de) 2007-12-24 2014-05-07 Honeywell Int Inc Reaktor zur quantitativen analyse von nukleinsäuren
US8986253B2 (en) 2008-01-25 2015-03-24 Tandem Diabetes Care, Inc. Two chamber pumps and related methods
US20110039033A1 (en) * 2008-01-31 2011-02-17 Erika Merschrod Method of depositing a polymer micropattern on a substrate
JP5283924B2 (ja) * 2008-02-21 2013-09-04 株式会社日立製作所 核酸増幅用デバイス
US9664619B2 (en) * 2008-04-28 2017-05-30 President And Fellows Of Harvard College Microfluidic device for storage and well-defined arrangement of droplets
US20090270269A1 (en) * 2008-04-28 2009-10-29 Ashok Kumar Nano-scale fluoro-biosensors exhibiting a low false alarm rate for rapid detection of biological contaminants
US9394184B1 (en) 2008-04-30 2016-07-19 Hitek Aqua Systems System for and method of regulating calcium hardness for a body of water
WO2009135117A1 (en) * 2008-05-02 2009-11-05 The Government Of The United States Of America, As Represented By The Secretary Of The Navy Selective membranes/thin films for analytical applications
US8181531B2 (en) * 2008-06-27 2012-05-22 Edwin Carlen Accessible stress-based electrostatic monitoring of chemical reactions and binding
US9011670B2 (en) * 2008-08-14 2015-04-21 The Charles Stark Draper Laboratory, Inc. Three-dimensional metal ion sensor arrays on printed circuit boards
US8939966B2 (en) * 2008-08-21 2015-01-27 University Of Florida Research Foundation, Inc. Differential laser-induced perturbation (DLIP) for bioimaging and chemical sensing
US9880137B2 (en) * 2008-09-04 2018-01-30 The Board Of Trustees Of The University Of Illinois Colorimetric sensor arrays based on nanoporous pigments
US20100058834A1 (en) * 2008-09-09 2010-03-11 Honeywell International Inc. Method and apparatus for low drift chemical sensor array
US8283165B2 (en) 2008-09-12 2012-10-09 Genvault Corporation Matrices and media for storage and stabilization of biomolecules
US8408421B2 (en) 2008-09-16 2013-04-02 Tandem Diabetes Care, Inc. Flow regulating stopcocks and related methods
CA2737461A1 (en) 2008-09-19 2010-03-25 Tandem Diabetes Care, Inc. Solute concentration measurement device and related methods
US20100075439A1 (en) * 2008-09-23 2010-03-25 Quanterix Corporation Ultra-sensitive detection of molecules by capture-and-release using reducing agents followed by quantification
US8222047B2 (en) 2008-09-23 2012-07-17 Quanterix Corporation Ultra-sensitive detection of molecules on single molecule arrays
US20100075862A1 (en) * 2008-09-23 2010-03-25 Quanterix Corporation High sensitivity determination of the concentration of analyte molecules or particles in a fluid sample
US8247216B2 (en) 2008-09-30 2012-08-21 Pacific Biosciences Of California, Inc. Ultra-high multiplex analytical systems and methods
US7923715B2 (en) * 2008-12-06 2011-04-12 The United States Of America As Represented By The Administrator Of National Aeronautics And Space Administration Chalcogenide nanoionic-based radio frequency switch
US20100147832A1 (en) * 2008-12-16 2010-06-17 Barker Iii Charles R Induction cookware identifying
US20100179074A1 (en) * 2009-01-15 2010-07-15 Honeywell International Inc. Methods and apparatus for fluid delivery and removal of micron scale structures
JP5587342B2 (ja) * 2009-01-26 2014-09-10 インディケーター システムズ インターナショナル, インコーポレイテッド 微生物からの代謝副産物の存在を検出するための指標
WO2010090810A2 (en) * 2009-02-05 2010-08-12 Hydradx, Inc. Diagnostic device and method
EP2221606A3 (de) * 2009-02-11 2012-06-06 Samsung Electronics Co., Ltd. Integrierter Biochip und Verfahren zur Herstellung des integrierten Biochips
JP4849278B2 (ja) * 2009-03-27 2012-01-11 セイコーエプソン株式会社 細胞処理デバイス、細胞処理カートリッジおよび体液処理システム
FI20095501A0 (fi) 2009-05-04 2009-05-04 Pekka Haenninen Menetelmä näytteiden karakterisoimiseksi ja/tai määrittämiseksi
US20120224053A1 (en) * 2009-06-17 2012-09-06 Board Of Regents, The University Of Texas System Method and apparatus for quantitative microimaging
CA2766597A1 (en) * 2009-07-01 2011-01-06 Board Of Regents, The University Of Texas System Methods of determining the presence and/or concentration of an analyte in a sample
US9554742B2 (en) 2009-07-20 2017-01-31 Optiscan Biomedical Corporation Fluid analysis system
WO2011011462A1 (en) 2009-07-20 2011-01-27 Optiscan Biomedical Corporation Adjustable connector and dead space reduction
US9523701B2 (en) 2009-07-29 2016-12-20 Dynex Technologies, Inc. Sample plate systems and methods
GB0913258D0 (en) * 2009-07-29 2009-09-02 Dynex Technologies Inc Reagent dispenser
US20110152770A1 (en) 2009-07-30 2011-06-23 Tandem Diabetes Care, Inc. Infusion pump system with disposable cartridge having pressure venting and pressure feedback
US11096708B2 (en) 2009-08-07 2021-08-24 Ulthera, Inc. Devices and methods for performing subcutaneous surgery
US9358064B2 (en) 2009-08-07 2016-06-07 Ulthera, Inc. Handpiece and methods for performing subcutaneous surgery
US8248255B2 (en) * 2009-10-13 2012-08-21 Verifuel Ltd. Optical fluid tester
CA2778270C (en) 2009-10-19 2021-01-05 Theranos, Inc. Integrated health data capture and analysis system
WO2011053845A2 (en) * 2009-10-30 2011-05-05 Illumina, Inc. Microvessels, microparticles, and methods of manufacturing and using the same
US9855735B2 (en) 2009-11-23 2018-01-02 Cyvek, Inc. Portable microfluidic assay devices and methods of manufacture and use
US9651568B2 (en) 2009-11-23 2017-05-16 Cyvek, Inc. Methods and systems for epi-fluorescent monitoring and scanning for microfluidic assays
US9500645B2 (en) 2009-11-23 2016-11-22 Cyvek, Inc. Micro-tube particles for microfluidic assays and methods of manufacture
US9759718B2 (en) 2009-11-23 2017-09-12 Cyvek, Inc. PDMS membrane-confined nucleic acid and antibody/antigen-functionalized microlength tube capture elements, and systems employing them, and methods of their use
US10065403B2 (en) 2009-11-23 2018-09-04 Cyvek, Inc. Microfluidic assay assemblies and methods of manufacture
US9700889B2 (en) 2009-11-23 2017-07-11 Cyvek, Inc. Methods and systems for manufacture of microarray assay systems, conducting microfluidic assays, and monitoring and scanning to obtain microfluidic assay results
CA2781556C (en) 2009-11-23 2015-05-19 Cyvek, Inc. Method and apparatus for performing assays
WO2013134742A2 (en) 2012-03-08 2013-09-12 Cyvek, Inc Micro-tube particles for microfluidic assays and methods of manufacture
EP2513626A2 (de) 2009-12-15 2012-10-24 Nomadics, Inc. System und verfahren zur erkennung mehrerer analyte
JP5663985B2 (ja) * 2009-12-16 2015-02-04 ソニー株式会社 マイクロビーズ検査用のセル及びマイクロビーズの解析方法
EP2343544B1 (de) * 2009-12-25 2015-03-11 Arkray, Inc. Verfahren zur Analyse von Hämoglobin durch Elektrophorese
US8640525B2 (en) * 2009-12-30 2014-02-04 Monsanto Technology Llc Methods and systems for differentiating soybeans
WO2011088588A1 (en) * 2010-01-20 2011-07-28 Honeywell International, Inc. Reactor for quantitative analysis of nucleic acids
US8338182B2 (en) * 2010-02-08 2012-12-25 Arizona Board of Regents, a body corporate acting for and on behalf of Arizona State University Methods and systems for fluid examination and remediation
EP2542890B1 (de) 2010-03-01 2015-05-06 Quanterix Corporation Verfahren zur erweiterung des dynamischen bereichs bei tests für den nachweis von molekülen oder partikeln
US8236574B2 (en) 2010-03-01 2012-08-07 Quanterix Corporation Ultra-sensitive detection of molecules or particles using beads or other capture objects
US9678068B2 (en) * 2010-03-01 2017-06-13 Quanterix Corporation Ultra-sensitive detection of molecules using dual detection methods
US8415171B2 (en) 2010-03-01 2013-04-09 Quanterix Corporation Methods and systems for extending dynamic range in assays for the detection of molecules or particles
US20110282247A1 (en) * 2010-03-31 2011-11-17 Helen Denise Novel Ovulation Predictor Device
US8363224B2 (en) 2010-03-31 2013-01-29 General Electric Company Fringe locking subsystem and methods of making and using the same
US20190300945A1 (en) 2010-04-05 2019-10-03 Prognosys Biosciences, Inc. Spatially Encoded Biological Assays
US10787701B2 (en) 2010-04-05 2020-09-29 Prognosys Biosciences, Inc. Spatially encoded biological assays
CA2799468A1 (en) 2010-05-14 2011-11-17 Mallinckrodt Llc Functional, cross-linked nanostructures for tandem optical imaging and therapy
EP2580589B1 (de) 2010-06-09 2016-08-31 Optiscan Biomedical Corporation Messung von analyten in einer flüssigkeitsprobe aus einem patienten
EP2397859B1 (de) 2010-06-15 2020-02-05 F. Hoffmann-La Roche AG Optische Überwachung des Mischens und Trennens
US20110308313A1 (en) * 2010-06-17 2011-12-22 Geneasys Pty Ltd Humidity sensor
US9612240B2 (en) 2010-06-29 2017-04-04 The Trustees Of The University Of Pennsylvania Biomimetic chemical sensors using nanoelectronic readout of olfactory receptors
CN103140292B (zh) * 2010-07-29 2015-01-21 丹耐克斯技术有限公司 样品板
US9671413B2 (en) 2010-11-12 2017-06-06 William Marsh Rice University Prostate cancer point of care diagnostics
WO2012065117A2 (en) 2010-11-12 2012-05-18 William Marsh Rice University Oral cancer point of care diagnostics
KR101037099B1 (ko) 2010-11-30 2011-05-25 주식회사 이바이오젠 비드챔버를 이용한 진동 교잡 바이오칩 반응 시스템
US8586913B2 (en) 2011-01-10 2013-11-19 Schlumberger Technology Corporation Fluidic density measurements based on beta particles detection
EP2481703B1 (de) * 2011-01-27 2020-07-01 Sensirion AG Sensorschutz
US9952237B2 (en) 2011-01-28 2018-04-24 Quanterix Corporation Systems, devices, and methods for ultra-sensitive detection of molecules or particles
CN103649759B (zh) 2011-03-22 2016-08-31 西维克公司 微流体装置以及制造方法和用途
US9252175B2 (en) 2011-03-23 2016-02-02 Nanohmics, Inc. Method for assembly of spectroscopic filter arrays using biomolecules
US9828696B2 (en) 2011-03-23 2017-11-28 Nanohmics, Inc. Method for assembly of analyte filter arrays using biomolecules
US20140302532A1 (en) 2011-04-12 2014-10-09 Quanterix Corporation Methods of determining a treatment protocol for and/or a prognosis of a patient's recovery from a brain injury
GB201106254D0 (en) 2011-04-13 2011-05-25 Frisen Jonas Method and product
WO2012155097A2 (en) * 2011-05-11 2012-11-15 Luminex Corporation Systems and methods for producing an evaporation barrier in a reaction chamber
SG194892A1 (en) 2011-05-12 2013-12-30 Univ Rice William M Bio-nano-chips for on-site drug screening
DE102011050389B4 (de) 2011-05-16 2021-09-02 Presens - Precision Sensing Gmbh Sensoreinheit und Messverfahren
US8660968B2 (en) * 2011-05-25 2014-02-25 Azure Vault Ltd. Remote chemical assay classification
JP5765081B2 (ja) * 2011-06-22 2015-08-19 ソニー株式会社 撮像素子、電子機器、製造方法、および検査装置
ITTO20110567A1 (it) * 2011-06-28 2012-12-29 St Microelectronics Srl Cartuccia per analisi biochimiche, sistema per analisi biochimiche e metodo per eseguire un processo biochimico
WO2013006716A1 (en) 2011-07-06 2013-01-10 Optiscan Biomedical Corporation Sample cell for fluid analysis system
WO2013019852A2 (en) 2011-08-01 2013-02-07 Tandem Diabetes Care, Inc. Therapy management system
KR101312272B1 (ko) * 2011-08-09 2013-09-25 삼성에스디아이 주식회사 광전변환소자
WO2013033359A1 (en) 2011-08-31 2013-03-07 The Trustees Of The University Of Pennsylvania Carbon nanotube biosensors and related methods
US20130078615A1 (en) * 2011-09-26 2013-03-28 Alberto Gandini Device and Method for Detection and Quantification of Immunological Proteins, Pathogenic and Microbial Agents and Cells
US20130092846A1 (en) * 2011-10-18 2013-04-18 Uwm Research Foundation, Inc. Fiber-optic sensors for real-time monitoring
KR101876540B1 (ko) 2011-12-28 2018-07-10 삼성디스플레이 주식회사 가요성 표시 장치 및 가요성 표시 장치의 제조 방법
US9075021B2 (en) 2012-02-17 2015-07-07 Toyota Motor Engineering & Manufacturing North America, Inc. Methods and systems for monitoring content of coating solutions using automated titration devices
US8850689B2 (en) * 2012-03-23 2014-10-07 Delta Electronics, Inc. Method for manufacturing switchable particle-based display using a pre-filling process
US10132802B2 (en) 2012-04-17 2018-11-20 i-calQ, LLC Device for performing a diagnostic test and methods for use thereof
WO2013158504A1 (en) * 2012-04-17 2013-10-24 Ehrenkranz Joel R L Device for performing diagnostic test and methods for use thereof
US9180242B2 (en) 2012-05-17 2015-11-10 Tandem Diabetes Care, Inc. Methods and devices for multiple fluid transfer
GB2502306A (en) * 2012-05-22 2013-11-27 Univ Singapore Microparticle sensor
EP2855020A2 (de) * 2012-06-01 2015-04-08 Vycap B.V. Diagnostische mikrosiebvorrichtung bei der isolierung und analyse von einzelzellen
US9555186B2 (en) 2012-06-05 2017-01-31 Tandem Diabetes Care, Inc. Infusion pump system with disposable cartridge having pressure venting and pressure feedback
WO2014034781A1 (ja) 2012-08-31 2014-03-06 国立大学法人東京大学 検出装置及び検出方法
US9310357B2 (en) 2012-09-28 2016-04-12 Src, Inc. Detection of chemical and biological agents using oligonucleotide aptamers
WO2014060483A1 (en) 2012-10-17 2014-04-24 Spatial Transcriptomics Ab Methods and product for optimising localised or spatial detection of gene expression in a tissue sample
US9932626B2 (en) 2013-01-15 2018-04-03 Quanterix Corporation Detection of DNA or RNA using single molecule arrays and other techniques
EP2948772B1 (de) * 2013-01-22 2018-10-10 Nitto Denko Corporation Hydrogel zur verwendung in einem biosensor mit optikbasiertem nachweis von analyten
EP2763065A1 (de) * 2013-01-31 2014-08-06 Sensirion AG Verfahren und System zur Identifizierung einer Flüssigkeitsprobe
WO2014121802A1 (en) * 2013-02-07 2014-08-14 Zaghloul Mohammad Hosam Eldeen Innovative nano-elisa single test for the detection of hcv, hiv antibodies and hbsag
US8995658B2 (en) 2013-02-13 2015-03-31 Honeywell International Inc. Physics-based key generation
US9173998B2 (en) 2013-03-14 2015-11-03 Tandem Diabetes Care, Inc. System and method for detecting occlusions in an infusion pump
US9492608B2 (en) 2013-03-15 2016-11-15 Tandem Diabetes Care, Inc. Method and device utilizing insulin delivery protocols
US9097712B2 (en) * 2013-03-15 2015-08-04 Allied Innovative Systems Llc Flow-through cell counting assay
US9248448B2 (en) 2013-04-24 2016-02-02 William Marsh Rice University Multisample bionanochip platform
ITVR20130132A1 (it) * 2013-05-29 2014-11-30 Optoelettronica Italia S R L Kit per il rilevamento di micro-rna estratto da un campione di fluido corporeo nonché metodo per il rilevamento dello stesso
GB2515490A (en) * 2013-06-24 2014-12-31 Univ Dublin City An aperture array substrate device, a detection system and a method for detecting analytes in a sample
US9868979B2 (en) 2013-06-25 2018-01-16 Prognosys Biosciences, Inc. Spatially encoded biological assays using a microfluidic device
GB201315327D0 (en) * 2013-08-28 2013-10-09 Anmat Technology Ltd Apparatus for detecting an analyte using a fluid having magnetic particles with a binding ligand for binding the analyte
CN103487880B (zh) * 2013-09-30 2016-05-25 南京华信藤仓光通信有限公司 使光纤束中光纤或光纤并带易剥离方法及硅油涂覆的装置
US9465960B2 (en) 2013-12-04 2016-10-11 Honeywell International Inc. Physics-based authentication
US10109612B2 (en) * 2013-12-13 2018-10-23 Taiwan Semiconductor Manufacturing Company Tools and systems for processing semiconductor devices, and methods of processing semiconductor devices
WO2015095239A1 (en) 2013-12-18 2015-06-25 Optiscan Biomedical Corporation Systems and methods for detecting leaks
TW201527756A (zh) * 2014-01-10 2015-07-16 Nat Univ Tsing Hua 提供食品安全地圖之方法、電腦程式產品、和系統
WO2015115471A1 (ja) * 2014-01-28 2015-08-06 国立大学法人大阪大学 観察装置、デバイス、デバイス製造方法、粒径測定方法、耐性観察方法、化学的反応方法、粒子保存方法、及び自動観察装置
WO2015121533A1 (en) * 2014-02-11 2015-08-20 Wallac Oy A device and a method for managing a sample to be analyzed and a solid sample carrier and liquid sample carrier
DE102014203266B4 (de) * 2014-02-24 2018-07-19 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Zusammensetzung mit FRET-Paar in definierter Geometrie
JP6480210B2 (ja) * 2014-02-28 2019-03-06 アークレイ株式会社 プラズマ発生用チップ、プラズマ発生装置およびプラズマ分光分析方法
GB2524541A (en) * 2014-03-26 2015-09-30 Ibm Microfluidic chip with conic bead trapping cavities and fabrication thereof
DE102014104595A1 (de) * 2014-04-01 2015-10-01 Michael Himmelhaus Verfahren und Vorrichtung zur labelfreien Detektion eines Analyten
US9466459B2 (en) * 2014-06-03 2016-10-11 Protochips, Inc. Method for optimizing fluid flow across a sample within an electron microscope sample holder
US10031104B2 (en) * 2014-06-13 2018-07-24 Yes Way Intellectual Holdings, Llc Mobile micro-lab for chemical analysis of fluids
US10520521B2 (en) 2014-06-30 2019-12-31 Phc Holdings Corporation Substrate for sample analysis, sample analysis device, sample analysis system, and program for sample analysis system
JP6588908B2 (ja) 2014-06-30 2019-10-09 Phcホールディングス株式会社 試料分析用基板、試料分析装置、試料分析システムおよび試料分析システム用プログラム
EP3163307B1 (de) 2014-06-30 2021-03-03 PHC Holdings Corporation Substrat zur probenanalyse, probenanalysevorrichtung, probenanalysesystem und verfahren zur entfernung von flüssigkeit aus einer flüssigkeit, die magnetische partikel enthält
WO2016002731A1 (ja) 2014-06-30 2016-01-07 パナソニックヘルスケアホールディングス株式会社 試料分析用基板および試料分析装置
US10416144B2 (en) 2014-07-28 2019-09-17 Kansas State University Research Foundation Nanosensors for detecting enzymatic activity in dairy production
AU2015302025B2 (en) * 2014-08-11 2021-08-19 The Regents Of The University Of California Continuous analyte sensor
WO2016036950A1 (en) 2014-09-05 2016-03-10 The Trustees Of The University Of Pennsylvania Volatile organic compound-based diagnostic systems and methods
KR102603422B1 (ko) 2014-09-29 2023-11-17 애버리 데니슨 코포레이션 타이어 트래킹 rfid 라벨
CN104406916A (zh) * 2014-11-04 2015-03-11 百度在线网络技术(北京)有限公司 食物的检测方法和装置
EP3232203B1 (de) 2014-12-12 2022-02-02 PHC Holdings Corporation Substrat zur probenanalyse, probenanalysevorrichtung, probenanalysesystem und programm für ein probenanalysesystem
AU2016200047A1 (en) * 2015-01-07 2016-07-21 Personal Genomics, Inc. Oriented Loading Systems And Method For Orienting A Particle Loaded In A Well
DE102015001998B3 (de) * 2015-02-20 2016-02-04 Friz Biochem Gesellschaft Für Bioanalytik Mbh Mikrofluidische Kartusche für den Nachweis von Biomolekülen
WO2016145300A1 (en) * 2015-03-11 2016-09-15 Nano Engineered Applications, Inc. Chemical sensor
WO2016161400A1 (en) * 2015-04-03 2016-10-06 Abbott Laboratories Devices and methods for sample analysis
EP4282977B1 (de) 2015-04-10 2024-06-05 10x Genomics Sweden AB Räumlich getrennte multiplex-nukleinsäureanalyse von biologischen proben
US9867250B1 (en) 2015-04-20 2018-01-09 The Arizona Board Of Regents On Behalf Of The University Of Arizona System having a configurable pico-second pulsed LED driver circuit and photomultiplier tube biasing and gating circuits for real-time, time-resolved transient recording of fluorescence
WO2016193181A1 (en) * 2015-05-29 2016-12-08 Nanoimmunotech, S.L. Biosensors, kits and assays for measuring metalloproteinase and serine protease activities
US10716500B2 (en) 2015-06-29 2020-07-21 Cardiac Pacemakers, Inc. Systems and methods for normalization of chemical sensor data based on fluid state changes
WO2017015230A1 (en) 2015-07-22 2017-01-26 Arizona Board Of Regents On Behalf Of Arizona State University Methods and systems for in situ temporary containment of shallow contaminated soils
US11521475B1 (en) 2015-08-31 2022-12-06 Hitek Aqua Systems System for and method remotely monitoring chemistry of recreational water facilities
WO2017058806A1 (en) * 2015-09-28 2017-04-06 The Regents Of The University Of California Wearable sensor arrays for in-situ body fluid analysis
US10228367B2 (en) 2015-12-01 2019-03-12 ProteinSimple Segmented multi-use automated assay cartridge
US10386365B2 (en) 2015-12-07 2019-08-20 Nanohmics, Inc. Methods for detecting and quantifying analytes using ionic species diffusion
US10386351B2 (en) 2015-12-07 2019-08-20 Nanohmics, Inc. Methods for detecting and quantifying analytes using gas species diffusion
US11988662B2 (en) 2015-12-07 2024-05-21 Nanohmics, Inc. Methods for detecting and quantifying gas species analytes using differential gas species diffusion
CA3008649A1 (en) 2015-12-16 2017-06-22 Siren Care, Inc. System and method for detecting inflammation in a foot
US10849600B2 (en) 2016-03-08 2020-12-01 Entech Instruments Inc. Breath condensate and saliva analysis using oral rinse
EP3430394A4 (de) 2016-03-18 2020-03-11 Connectedyard, Inc. Chemikalienüberwachungsvorrichtungen und -verfahren
US10190973B2 (en) * 2016-03-31 2019-01-29 Sensor Electronic Technology, Inc. Integrated ultraviolet analyzer
US10926025B2 (en) 2016-09-15 2021-02-23 Tandem Diabetes Care, Inc. Vial supporter for medicament pump
US20180077894A1 (en) * 2016-09-22 2018-03-22 Src, Inc. Methods and systems for detection and tracking of mastitis in dairy cattle
US10357603B2 (en) 2017-01-11 2019-07-23 Tandem Diabetes Care, Inc. Electromagnetic signal-based infusion pump control
RU175245U1 (ru) * 2017-01-13 2017-11-28 Сергей Викторович Минаев Сепарационное устройство для определения биохимических показателей и маркеров заболеваний в плазме крови
EP3577438B1 (de) * 2017-01-31 2025-02-26 Bahçesehir Üniversitesi Unterwasserlichtquelle
US20180246071A1 (en) * 2017-02-28 2018-08-30 Entech Instruments Inc. Increasing the Sensitivity of Gas Chromatography and Gas Chromatography-Mass Spectrometry Analysis By Allowing Relatively Large Solvent Volume Injections While Reducing Sample Loss And System Contamination
US10641733B2 (en) * 2017-03-20 2020-05-05 National Technology & Engineering Solutions Of Sandia, Llc Active mechanical-environmental-thermal MEMS device for nanoscale characterization
WO2018175500A1 (en) 2017-03-21 2018-09-27 Hexanomics, Inc. Sealed microwell assay
AU2018239360C1 (en) 2017-03-21 2023-11-02 Hayward Industries, Inc. Systems and methods for sanitizing pool and spa water
US10429303B2 (en) * 2017-03-24 2019-10-01 International Business Machines Corporation Portable and autonomous, IoT enabled, optical measurement system
GB201708339D0 (en) * 2017-05-24 2017-07-05 Univ Court Univ Of Glasgow Metabolite detection apparatus and method of detecting metabolites
US10684277B2 (en) * 2017-07-24 2020-06-16 Comsats Institute Of Information Technology Colorimetric filter paper assay for rapid monitoring of cholesterol level
CN107621455A (zh) * 2017-08-02 2018-01-23 广西中医药大学制药厂 壮药材藤苦参中总强心苷含量的测定方法
CN110892247B (zh) 2017-08-17 2023-08-25 雅培医护站股份有限公司 用于执行光学和电化学测定的设备、系统和方法
EP3669173A1 (de) * 2017-08-17 2020-06-24 Abbott Point of Care Inc. Verfahren zur abbildung von testkügelchen in einer biologischen probe
CN110869745B (zh) 2017-08-17 2023-08-11 雅培医护站股份有限公司 用于执行光学测定的设备、系统和方法
US20190054466A1 (en) * 2017-08-17 2019-02-21 Abbott Point Of Care Inc. Single-use test device for imaging blood cells
WO2019035086A1 (en) * 2017-08-17 2019-02-21 Abbott Point Of Care Inc. SINGLE-USE TEST DEVICE FOR THE IMAGING OF DOSING BALLS
WO2019035085A1 (en) * 2017-08-17 2019-02-21 Abbott Point Of Care Inc. METHOD FOR IMAGING BLOOD CELLS
EP3460472B1 (de) * 2017-09-22 2024-09-18 Nokia Technologies Oy Funktionalisierte partikel
CN111295577A (zh) * 2017-11-01 2020-06-16 小利兰·斯坦福大学托管委员会 分析物检测方法
US20190137481A1 (en) 2017-11-03 2019-05-09 The Regents Of The University Of California Device and method for cell-based drug screening
WO2019118445A1 (en) * 2017-12-12 2019-06-20 Trustees Of Boston University Disposable fluidic cartridge for interferometric reflectance imaging sensor
ES2956109T3 (es) * 2018-02-15 2023-12-13 Procisedx Inc Analizador
WO2019173501A1 (en) 2018-03-06 2019-09-12 Entech Instruments Inc. Ventilator-coupled sampling device and method
US11561221B2 (en) 2018-05-02 2023-01-24 Trustees Of Boston University Dynamic tracking of captured targets for enhanced digital biosensing
EP3820610A1 (de) 2018-07-12 2021-05-19 Luminex Corporation Systeme und verfahren zur durchführung variabler probenvorbereitung und analyseverfahren
EP3593708B1 (de) 2018-07-13 2024-08-28 Nokia Technologies Oy Künstliche haut
CN112513630B (zh) 2018-07-31 2023-05-12 因泰科设备股份有限公司 混合毛细管/填充捕集器及使用方法
CN108956760A (zh) * 2018-08-01 2018-12-07 京东方科技集团股份有限公司 检测装置及检测系统
CN110819523B (zh) * 2018-08-13 2023-08-29 上海新微技术研发中心有限公司 一种数字pcr系统及数字pcr液滴形成方法
US11592427B2 (en) * 2018-10-01 2023-02-28 Brown University Multi-parametric machine olfaction
KR102145883B1 (ko) * 2018-12-17 2020-08-20 고려대학교 산학협력단 단일 입자 분석을 위한 다공성 막
US12233240B2 (en) 2018-12-26 2025-02-25 Tandem Diabetes Care, Inc. Methods of wireless communication in an infusion pump system
JP2022516556A (ja) * 2019-01-03 2022-02-28 ピクセル メディカル テクノロジーズ リミテッド 流体サンプルを分析するシステム及び方法
EP3927391A4 (de) 2019-02-19 2022-11-16 Tandem Diabetes Care, Inc. System und verfahren zur paarung einer infusionspumpe mit einer fernsteuerungsvorrichtung
EP3702776A3 (de) * 2019-02-26 2020-09-16 Pentair Water Pool and Spa, Inc. System und verfahren zur überwachung der wasserqualität
WO2020180327A1 (en) * 2019-03-07 2020-09-10 Hewlett-Packard Development Company, L.P. Nucleic acid detection
DE102019106194B4 (de) * 2019-03-12 2020-12-03 Surflay Nanotec Gmbh Vorrichtung zur spektroskopischen Bestimmung der Bindungskinetik eines Analyten
WO2020198422A1 (en) 2019-03-26 2020-10-01 Tandem Diabetes Care, Inc. Method of pairing an infusion pump with a remote control device
US11143502B2 (en) 2019-03-29 2021-10-12 Polymer Technology Systems, Inc. Systems and methods for test strip insertion positioning check and type match
WO2020210981A1 (en) * 2019-04-16 2020-10-22 Boe Technology Group Co., Ltd. Micro-channel device and manufacturing method thereof and micro-fluidic system
WO2020247662A1 (en) * 2019-06-04 2020-12-10 The Regents Of The University Of California Diboronic acid compounds and methods of making and using thereof
US20220276235A1 (en) * 2019-07-18 2022-09-01 Essenlix Corporation Imaging based homogeneous assay
KR102751768B1 (ko) * 2019-07-26 2025-01-07 엘지디스플레이 주식회사 형광 디스플레이 센서
RU2722604C1 (ru) * 2019-08-01 2020-06-02 федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный университет" (ФГБОУ ВО "ВГУ") Устройство для спектрального анализа
US11327084B2 (en) * 2019-09-19 2022-05-10 Invidx Corp. Joint hematology and biochemistry point-of-care testing system
US12157124B2 (en) 2019-11-06 2024-12-03 10X Genomics, Inc. Imaging system hardware
KR20220112816A (ko) 2019-12-10 2022-08-11 란타 인코포레이티드 화학 분석 및 관련 방법을 위한 프로브
KR20220116509A (ko) 2019-12-17 2022-08-23 란타 인코포레이티드 화학 분석을 위한 모바일 디바이스 및 관련 방법
CN111229337B (zh) * 2020-01-17 2021-11-30 上海新微技术研发中心有限公司 光波导多微流道芯片的制造方法
US12405264B2 (en) 2020-01-17 2025-09-02 10X Genomics, Inc. Electrophoretic system and method for analyte capture
US20210325380A1 (en) * 2020-04-20 2021-10-21 EnLiSense, LLC Disease diagnostics using a multi-configurable sensing array
US12416603B2 (en) 2020-05-19 2025-09-16 10X Genomics, Inc. Electrophoresis cassettes and instrumentation
EP4414459B1 (de) 2020-05-22 2025-09-03 10X Genomics, Inc. Simultane räumlich-zeitliche messung der genexpression und der zellaktivität
US20210379578A1 (en) * 2020-06-04 2021-12-09 Illumina, Inc. Apparatus with a sensor having an active surface
US12031177B1 (en) 2020-06-04 2024-07-09 10X Genomics, Inc. Methods of enhancing spatial resolution of transcripts
WO2021252747A1 (en) 2020-06-10 2021-12-16 1Ox Genomics, Inc. Fluid delivery methods
CN111924541B (zh) * 2020-07-01 2021-12-07 山东聊城华阳医药辅料有限公司 一种基于光敏电阻值特性的气动管道输送装置
US12560581B2 (en) 2020-08-11 2026-02-24 Entech Instruments Inc. System and method of matrix accelerated vacuum-assisted sorbent extraction for improved sample preparation prior to GCMS analysis
US12399172B2 (en) 2020-09-18 2025-08-26 Salvus, Llc Interferometric detection and quantification system and methods of use in healthcare
US20220091031A1 (en) * 2020-09-18 2022-03-24 Salvus, Llc Interferometric Detection and Quantification System and Methods of Use in Chemical Processing
US11740177B2 (en) 2020-09-18 2023-08-29 Salvus, Llc Interferometric detection and quantification system and methods of use in aquatics
EP4214678B1 (de) 2020-09-18 2024-11-06 10X Genomics, Inc. Probenhandhabungsvorrichtung und bildregistrierungsverfahren
US11994504B2 (en) 2020-09-18 2024-05-28 Salvus, Llc Interferometric detection and quantification system and methods of use in food processing and food supply chain
WO2022093212A1 (en) * 2020-10-28 2022-05-05 Hewlett-Packard Development Company, L.P. Self-wicking assay devices
CN115315826B (zh) * 2020-11-18 2025-05-23 株式会社Lg新能源 自动电极干燥控制系统和自动电极干燥控制方法
US20240014010A1 (en) * 2021-02-19 2024-01-11 Hitachi High-Tech Corporation Plasma processing apparatus
WO2022178267A2 (en) 2021-02-19 2022-08-25 10X Genomics, Inc. Modular assay support devices
US20220365015A1 (en) * 2021-05-17 2022-11-17 Rhythmic Health, Inc. Mip sensor device with replaceable mip sensor
WO2022251538A1 (en) * 2021-05-27 2022-12-01 Siren Care, Inc. Sensor arrangements for a sensing garment
CN113358619B (zh) * 2021-06-05 2023-05-19 中国科学院新疆理化技术研究所 一种用于半定量检测高锰酸钾溶液的荧光传感分析卡制备方法及应用
CN113252862B (zh) * 2021-07-14 2021-09-17 四川久环环境技术有限责任公司 一种水质监测站
US12553805B2 (en) 2021-08-02 2026-02-17 10X Genomics, Inc. Methods of preserving a biological sample
USD1064308S1 (en) 2021-09-17 2025-02-25 10X Genomics, Inc. Sample handling device
CN114015560B (zh) * 2021-10-20 2024-07-05 深圳市中科先见医疗科技有限公司 一种分子检测芯片
EP4441711A1 (de) 2021-12-20 2024-10-09 10X Genomics, Inc. Selbsttest für eine pathologie-/histologie-objektträgerbildgebungsvorrichtung
GB2623953A (en) * 2022-10-31 2024-05-08 Mighton Products Ltd Door lock assembly

Family Cites Families (223)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1501661A (fr) * 1965-11-29 1967-11-10 Witco Chemical Corp Composition détergente liquide, stable, polyfonctionnelle, active à cent pour cent, et son procédé de production
US3587040A (en) 1968-08-12 1971-06-22 Qonaar Corp Vehicle detector
US3696932A (en) 1970-09-30 1972-10-10 Pall Corp Disposable filter assembly
US3701433A (en) 1970-11-10 1972-10-31 Pall Corp Filter for use in the filtration of blood
US3709868A (en) * 1971-03-08 1973-01-09 Hoffmann La Roche Opium alkaloid antigens and antibodies specific therefor
US3843696A (en) * 1972-09-05 1974-10-22 Syva Co Methadone analog compounds
US3775742A (en) 1972-09-18 1973-11-27 Canoga Controls Corp Vehicle detection system
CS164231B2 (de) 1972-09-28 1975-11-07
US3856469A (en) 1973-01-02 1974-12-24 Syva Corp Interferant removal from amphetamine immunoassay
US3954623A (en) * 1974-05-28 1976-05-04 Johnson & Johnson Blood filtration unit
US3876504A (en) 1974-06-10 1975-04-08 Early Warning Co Procedure for determination of antigens and antibodies and articles for use therewith
US4189382A (en) 1974-11-07 1980-02-19 Sherwood Medical Industries Inc. Blood coagulation and separation
US4036946A (en) 1975-10-20 1977-07-19 Marcos Kleinerman Immunofluorometric method for measuring minute quantities of antigens, antibodies and other substances
US4050898A (en) 1976-04-26 1977-09-27 Eastman Kodak Company Integral analytical element
US4069017A (en) 1977-01-14 1978-01-17 Eastman Kodak Company Colorimetric assay for bilirubin
US4200613A (en) * 1977-06-03 1980-04-29 Ramco Laboratories Inc. Radioimmunoassay apparatus
US4115277A (en) 1977-06-17 1978-09-19 Pioneer Filters, Inc. Blood filtering apparatus of graduated fiber density
US4294817A (en) 1977-11-25 1981-10-13 International Diagnostic Technology, Inc. Method of fluoro immunoassay
US4245041A (en) 1977-12-07 1981-01-13 American Monitor Corporation Triglycerides assay and reagents therefor
US4246107A (en) * 1978-03-06 1981-01-20 Asahi Kasei Kogyo Kabushiki Kaisha Separation of lymphocytes from lymphocyte-containing suspension by filtration
US4378429A (en) 1979-08-23 1983-03-29 Modrovich Ivan Endre Enzymatic method and stabilized solutions for determining total cholesterol in human serum
JPS5659802A (en) 1979-10-23 1981-05-23 Shinroihi Kk Microspherical polymer particle and production thereof
US4344743A (en) * 1979-12-04 1982-08-17 Bessman Samuel P Piezoelectric driven diaphragm micro-pump
DE3029579C2 (de) * 1980-08-05 1985-12-12 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren und Mittel zur Abtrennung von Plasma oder Serum aus Vollblut
US4596657A (en) 1982-06-04 1986-06-24 Miles Laboratories, Inc. Blood bag system with integral filtering means
US4588665A (en) * 1982-11-22 1986-05-13 Drexler Technology Corporation Micrographic film member with laser written data
US4567149A (en) 1983-03-17 1986-01-28 Mast Immunosystems, Ltd. Binding assay system and method of making and using same
US4493815A (en) * 1983-07-28 1985-01-15 Bio-Rad Laboratories, Inc. Supporting and filtering biochemical test plate assembly
US4672028A (en) * 1984-05-23 1987-06-09 Icn Micromedic Systems, Inc. Compositions and method for simultaneous multiple array of analytes using radioisotope chelate labels
US4681742A (en) 1984-10-01 1987-07-21 Cetus Corporation Assay tray
JPH0823558B2 (ja) * 1984-11-27 1996-03-06 オ−ジエニクス リミテツド 検定装置
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5354825A (en) 1985-04-08 1994-10-11 Klainer Stanley M Surface-bound fluorescent polymers and related methods of synthesis and use
US4661445A (en) * 1985-05-24 1987-04-28 Saxinger W Carl Competitive ELISA for the detection of HTLV-III antibodies
US4623461A (en) 1985-05-31 1986-11-18 Murex Corporation Transverse flow diagnostic device
US5597531A (en) 1985-10-04 1997-01-28 Immunivest Corporation Resuspendable coated magnetic particles and stable magnetic particle suspensions
US4795698A (en) 1985-10-04 1989-01-03 Immunicon Corporation Magnetic-polymer particles
US4855225A (en) 1986-02-07 1989-08-08 Applied Biosystems, Inc. Method of detecting electrophoretically separated oligonucleotides
US4810378A (en) 1986-04-21 1989-03-07 Miles Laboratories, Inc. Red blood cell filtering system
US5143853A (en) 1986-06-25 1992-09-01 Trustees Of Tufts College Absorbance modulated fluorescence detection methods and sensors
US5252494A (en) * 1986-06-25 1993-10-12 Trustees Of Tufts College Fiber optic sensors, apparatus, and detection methods using controlled release polymers and reagent formulations held within a polymeric reaction matrix
US4935346A (en) 1986-08-13 1990-06-19 Lifescan, Inc. Minimum procedure system for the determination of analytes
US4753776A (en) 1986-10-29 1988-06-28 Biotrack, Inc. Blood separation device comprising a filter and a capillary flow pathway exiting the filter
CH672383A5 (de) 1986-10-29 1989-11-15 Baumer Electric Ag
US4925800A (en) * 1986-12-04 1990-05-15 The United States Of America As Represented By The Department Of Health And Human Services Monoclonal antibody against human pneumocystis carinii
US4813277A (en) 1987-03-30 1989-03-21 Amoco Corporation Method for collecting magnetizable particles in an above ground storage tank
US4828386A (en) * 1987-06-19 1989-05-09 Pall Corporation Multiwell plates containing membrane inserts
US4988618A (en) 1987-11-16 1991-01-29 Gene-Trak Systems Magnetic separation device and methods for use in heterogeneous assays
US5209904A (en) 1987-12-23 1993-05-11 Abbott Laboratories Agglutination reaction device utilizing selectively impregnated porous material
US4938742A (en) 1988-02-04 1990-07-03 Smits Johannes G Piezoelectric micropump with microvalves
US5162863A (en) 1988-02-15 1992-11-10 Canon Kabushiki Kaisha Method and apparatus for inspecting a specimen by optical detection of antibody/antigen sensitized carriers
EP0339623B1 (de) 1988-04-26 1993-12-15 Nippon Telegraph And Telephone Corporation Lasermagnetisches Immuntestverfahren und Gerät dazu
US4874499A (en) 1988-05-23 1989-10-17 Massachusetts Institute Of Technology Electrochemical microsensors and method of making such sensors
US5252294A (en) * 1988-06-01 1993-10-12 Messerschmitt-Bolkow-Blohm Gmbh Micromechanical structure
US4908112A (en) 1988-06-16 1990-03-13 E. I. Du Pont De Nemours & Co. Silicon semiconductor wafer for analyzing micronic biological samples
US5130238A (en) * 1988-06-24 1992-07-14 Cangene Corporation Enhanced nucleic acid amplification process
DE68926504T2 (de) 1988-07-20 1996-09-12 David Segev Verfahren zur amplifizierung und zum nachweis von nukleinsäuresequenzen
IT1226712B (it) 1988-08-05 1991-02-05 Eniricerche Spa Metodo immunoenzimatico elisa monopiastra con inibizione competitiva per la rivelazione di anticorpi antisporozoitari di plasmodium falciparum.
US5108933A (en) * 1988-09-16 1992-04-28 Immunicon Corporation Manipulation of colloids for facilitating magnetic separations
FR2638848B1 (fr) 1988-11-04 1993-01-22 Chemunex Sa Procede de detection et/ou de dosage dans un milieu liquide ou semi-liquide d'au moins une substance organique, biologique ou medicamenteuse soluble, par une methode d'agglutination
IE67038B1 (en) 1988-12-22 1996-02-21 Patrick Joseph Joyce Immunodiagnostic assays for use in the detection and determination of mastitis
US6008031A (en) 1989-05-12 1999-12-28 Duke University Method of analysis and manipulation of DNA utilizing mismatch repair systems
US5491097A (en) * 1989-06-15 1996-02-13 Biocircuits Corporation Analyte detection with multilayered bioelectronic conductivity sensors
US5156810A (en) * 1989-06-15 1992-10-20 Biocircuits Corporation Biosensors employing electrical, optical and mechanical signals
US5053197A (en) * 1989-07-19 1991-10-01 Pb Diagnostic Systems, Inc. Diagnostic assay module
JP3127449B2 (ja) 1989-07-28 2001-01-22 三菱化学株式会社 抗体の測定法
US5698271A (en) * 1989-08-22 1997-12-16 Immunivest Corporation Methods for the manufacture of magnetically responsive particles
CA2024548C (en) 1989-09-05 2002-05-28 David Issachar Analyte specific chemical sensor
US5541057A (en) * 1989-09-18 1996-07-30 Biostar, Inc. Methods for detection of an analyte
US5137833A (en) 1989-09-21 1992-08-11 Russell Anthony P Method for detecting polyhydroxyl compounds
US5366860A (en) 1989-09-29 1994-11-22 Applied Biosystems, Inc. Spectrally resolvable rhodamine dyes for nucleic acid sequence determination
US5188934A (en) 1989-11-14 1993-02-23 Applied Biosystems, Inc. 4,7-dichlorofluorescein dyes as molecular probes
US4997577A (en) 1989-12-20 1991-03-05 Baxter International Inc. Systems and methods for removing undesired matter from blood cells
US5547682A (en) * 1989-12-22 1996-08-20 Bioquest, Incorporated Preparation and use of novel injectable RES avoiding inorganic particles for medical application
ATE137269T1 (de) 1990-01-26 1996-05-15 Abbott Lab Verbessertes verfahren zur amplifikation von nuklein säurezielsequenz, einsetzbar für die polymerase und ligasekettenreaktion
US5183740A (en) 1990-02-23 1993-02-02 The United States Of America As Represented By The Secretary Of The Navy Flow immunosensor method and apparatus
US5182366A (en) 1990-05-15 1993-01-26 Huebner Verena D Controlled synthesis of peptide mixtures using mixed resins
US5965695A (en) 1990-05-15 1999-10-12 Chiron Corporation Modified peptide and peptide libraries with protease resistance, derivatives thereof and methods of producing and screening such
US5240640A (en) * 1990-06-04 1993-08-31 Coulter Corporation In situ use of gelatin or an aminodextran in the preparation of uniform ferrite particles
US5223393A (en) 1990-06-12 1993-06-29 Microgenics Corporation Detection of analytes having binding sites for at least two binding moieties
WO1992000880A1 (en) 1990-07-09 1992-01-23 S.C.I. Operations Pty Limited Trading As Smorgon Plastics An improved container
US5147606A (en) 1990-08-06 1992-09-15 Miles Inc. Self-metering fluid analysis device
US5071076A (en) 1990-08-10 1991-12-10 Omni Quest Corporation Method for producing magnetic microparticles from metallocenes
US5235028A (en) * 1990-08-31 1993-08-10 University Of Minnesota Polyethylene glycol derivatives for solid-phase applications
US5250264A (en) * 1991-01-25 1993-10-05 Trustees Of Tufts College Method of making imaging fiber optic sensors to concurrently detect multiple analytes of interest in a fluid sample
US5244813A (en) 1991-01-25 1993-09-14 Trustees Of Tufts College Fiber optic sensor, apparatus, and methods for detecting an organic analyte in a fluid or vapor sample
US5244636A (en) 1991-01-25 1993-09-14 Trustees Of Tufts College Imaging fiber optic array sensors, apparatus, and methods for concurrently detecting multiple analytes of interest in a fluid sample
US5235039A (en) 1991-06-10 1993-08-10 Eli Lilly And Company Substrates for hiv protease
US5578444A (en) 1991-06-27 1996-11-26 Genelabs Technologies, Inc. Sequence-directed DNA-binding molecules compositions and methods
WO1993002360A1 (en) 1991-07-16 1993-02-04 Transmed Biotech Incorporated Methods and compositions for simultaneous analysis of multiple analytes
US5837552A (en) 1991-07-22 1998-11-17 Medifor, Ltd. Surface-enhanced analytical procedures and substrates
US5211850A (en) 1991-07-26 1993-05-18 Research Medical, Inc. Plasma filter sorbent system for removal of components from blood
US5288214A (en) 1991-09-30 1994-02-22 Toshio Fukuda Micropump
US5846708A (en) * 1991-11-19 1998-12-08 Massachusetts Institiute Of Technology Optical and electrical methods and apparatus for molecule detection
DE69233087T2 (de) * 1991-11-22 2003-12-24 Affymetrix, Inc. (N.D.Ges.D.Staates Delaware) Verfahren zur Herstellung von Polymerarrays
JPH05157684A (ja) 1991-12-02 1993-06-25 Seikagaku Kogyo Co Ltd 吸光光度計
US6063581A (en) * 1992-01-22 2000-05-16 Axis-Shield Asa Immunoassay for homocysteine
US5262127A (en) 1992-02-12 1993-11-16 The Regents Of The University Of Michigan Solid state chemical micro-reservoirs
US5654497A (en) * 1992-03-03 1997-08-05 Lockheed Martin Energy Systems, Inc. Motor vehicle fuel analyzer
US5391272A (en) 1992-03-06 1995-02-21 Andcare, Inc. Electrochemical immunoassay methods
US5518887A (en) 1992-03-30 1996-05-21 Abbott Laboratories Immunoassays empolying generic anti-hapten antibodies and materials for use therein
US5248742A (en) 1992-04-27 1993-09-28 Gencorp Inc. Unsaturated polyester-epoxy resin network composition
US5587128A (en) 1992-05-01 1996-12-24 The Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification devices
US5637469A (en) * 1992-05-01 1997-06-10 Trustees Of The University Of Pennsylvania Methods and apparatus for the detection of an analyte utilizing mesoscale flow systems
US5296375A (en) * 1992-05-01 1994-03-22 Trustees Of The University Of Pennsylvania Mesoscale sperm handling devices
US5278303A (en) 1992-06-12 1994-01-11 University Of Toronto Innovations Foundation Polymer-supported solution synthesis of oligosaccharides
US5674698A (en) 1992-09-14 1997-10-07 Sri International Up-converting reporters for biological and other assays using laser excitation techniques
WO1994019690A1 (en) 1993-02-17 1994-09-01 Cardiovascular Diagnostics, Inc. Dry chemistry cascade immunoassay and affinity assay
US5503985A (en) 1993-02-18 1996-04-02 Cathey; Cheryl A. Disposable device for diagnostic assays
US5677196A (en) 1993-05-18 1997-10-14 University Of Utah Research Foundation Apparatus and methods for multi-analyte homogeneous fluoro-immunoassays
GB9311988D0 (en) 1993-06-10 1993-07-28 Pall Corp Device and method for separating plasma from a blood product
US6087186A (en) * 1993-07-16 2000-07-11 Irori Methods and apparatus for synthesizing labeled combinatorial chemistry libraries
US5382512A (en) 1993-08-23 1995-01-17 Chiron Corporation Assay device with captured particle reagent
FR2710410B1 (fr) 1993-09-20 1995-10-20 Bio Merieux Procédé et dispositif pour la détermination d'un analyte dans un échantillon .
US5472672A (en) * 1993-10-22 1995-12-05 The Board Of Trustees Of The Leland Stanford Junior University Apparatus and method for polymer synthesis using arrays
JP3488465B2 (ja) 1993-10-28 2004-01-19 ヒューストン・アドバンスド・リサーチ・センター 結合反応を別々に検出する微細加工フロースルー多孔性装置
US5499909A (en) 1993-11-17 1996-03-19 Aisin Seiki Kabushiki Kaisha Of Kariya Pneumatically driven micro-pump
AU681470B2 (en) 1993-12-28 1997-08-28 Westonbridge International Limited Micropump
US5616698A (en) 1994-01-10 1997-04-01 University Of Toronto Innovations Foundation Polymer-supported solution synthesis of oligosaccharides
US5631130A (en) 1994-05-13 1997-05-20 Abbott Laboratories Materials and methods for the detection of Mycobacterium tuberculosis
US5583162A (en) 1994-06-06 1996-12-10 Biopore Corporation Polymeric microbeads and method of preparation
DE69527585T2 (de) * 1994-06-08 2003-04-03 Affymetrix, Inc. Verfahren und Vorrichtung zum Verpacken von Chips
US5622821A (en) * 1994-06-29 1997-04-22 The Regents Of The University Of California Luminescent lanthanide chelates and methods of use
JPH0842457A (ja) 1994-07-27 1996-02-13 Aisin Seiki Co Ltd マイクロポンプ
US5512490A (en) 1994-08-11 1996-04-30 Trustees Of Tufts College Optical sensor, optical sensing apparatus, and methods for detecting an analyte of interest using spectral recognition patterns
US5965590A (en) 1994-09-08 1999-10-12 Romark Lab Lc Method for treatment of opportunistic infections with pharmaceutical compositions of tizoxanide and nitazoxanide
AUPM807094A0 (en) * 1994-09-09 1994-10-06 Commonwealth Scientific And Industrial Research Organisation Polymer beads and method for preparation thereof
WO1998053300A2 (en) 1997-05-23 1998-11-26 Lynx Therapeutics, Inc. System and apparaus for sequential processing of analytes
US5632876A (en) * 1995-06-06 1997-05-27 David Sarnoff Research Center, Inc. Apparatus and methods for controlling fluid flow in microchannels
KR100314996B1 (ko) 1994-11-10 2002-01-15 윌리암 제이. 버크 액체분배시스템
US5603351A (en) * 1995-06-07 1997-02-18 David Sarnoff Research Center, Inc. Method and system for inhibiting cross-contamination in fluids of combinatorial chemistry device
US5585069A (en) * 1994-11-10 1996-12-17 David Sarnoff Research Center, Inc. Partitioned microelectronic and fluidic device array for clinical diagnostics and chemical synthesis
US5616790A (en) 1994-11-18 1997-04-01 California Institute Of Technology Lipid-based metal sensor
US5550373A (en) 1994-12-30 1996-08-27 Honeywell Inc. Fabry-Perot micro filter-detector
US5571401A (en) 1995-03-27 1996-11-05 California Institute Of Technology Sensor arrays for detecting analytes in fluids
GB2300258A (en) 1995-04-28 1996-10-30 Philip John Jewess A separation device for magnetisable particles
US5834318A (en) 1995-05-10 1998-11-10 Bayer Corporation Screening of combinatorial peptide libraries for selection of peptide ligand useful in affinity purification of target proteins
US6524532B1 (en) * 1995-06-20 2003-02-25 The Regents Of The University Of California Microfabricated sleeve devices for chemical reactions
US6168948B1 (en) 1995-06-29 2001-01-02 Affymetrix, Inc. Miniaturized genetic analysis systems and methods
US5856174A (en) * 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
US5690807A (en) 1995-08-03 1997-11-25 Massachusetts Institute Of Technology Method for producing semiconductor particles
US5843655A (en) 1995-09-18 1998-12-01 Affymetrix, Inc. Methods for testing oligonucleotide arrays
US5863975A (en) 1995-10-03 1999-01-26 Rheox Inc. Aqueous construction compositions with improved water retention properties and a process for providing water retention properties to aqueous construction compositions
US5714122A (en) 1995-11-22 1998-02-03 Minnesota Mining And Manufacturing Company Emulsion for robust sensing
US5705018A (en) 1995-12-13 1998-01-06 Hartley; Frank T. Micromachined peristaltic pump
US5814524A (en) * 1995-12-14 1998-09-29 Trustees Of Tufts College Optical sensor apparatus for far-field viewing and making optical analytical measurements at remote locations
WO1997025437A1 (en) 1996-01-04 1997-07-17 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Method for assaying proteolytic enzymes using fluorescence-quenched substrates
JP3664328B2 (ja) 1996-01-19 2005-06-22 富士写真フイルム株式会社 血漿または血清試料の調製方法
US6013440A (en) * 1996-03-11 2000-01-11 Affymetrix, Inc. Nucleic acid affinity columns
US5747349A (en) 1996-03-20 1998-05-05 University Of Washington Fluorescent reporter beads for fluid analysis
US5840256A (en) 1996-04-09 1998-11-24 David Sarnoff Research Center Inc. Plate for reaction system
US5879632A (en) * 1996-04-09 1999-03-09 Sarnoff Corporation Apportioning system
US5788814A (en) 1996-04-09 1998-08-04 David Sarnoff Research Center Chucks and methods for positioning multiple objects on a substrate
JPH09281045A (ja) * 1996-04-10 1997-10-31 Kdk Corp メバロン酸の光学的測定方法
US5942443A (en) 1996-06-28 1999-08-24 Caliper Technologies Corporation High throughput screening assay systems in microscale fluidic devices
JP3950493B2 (ja) * 1996-04-26 2007-08-01 東レ・ダウコーニング株式会社 導電性シリコーンゴム組成物、半導体装置の製造方法およびその半導体装置
FR2749082B1 (fr) 1996-05-24 1998-06-26 Bio Merieux Particules superparamagnetiques et monodispersees
US6103479A (en) * 1996-05-30 2000-08-15 Cellomics, Inc. Miniaturized cell array methods and apparatus for cell-based screening
US5866430A (en) * 1996-06-13 1999-02-02 Grow; Ann E. Raman optrode processes and devices for detection of chemicals and microorganisms
US5770370A (en) 1996-06-14 1998-06-23 David Sarnoff Research Center, Inc. Nuclease protection assays
US5797898A (en) * 1996-07-02 1998-08-25 Massachusetts Institute Of Technology Microchip drug delivery devices
GB2315131B (en) 1996-07-10 2000-11-29 Cambridge Imaging Ltd Improvements in and relating to imaging
US5707502A (en) 1996-07-12 1998-01-13 Chiron Diagnostics Corporation Sensors for measuring analyte concentrations and methods of making same
US5872623A (en) * 1996-09-26 1999-02-16 Sarnoff Corporation Massively parallel detection
US5854684A (en) * 1996-09-26 1998-12-29 Sarnoff Corporation Massively parallel detection
US5861658A (en) 1996-10-03 1999-01-19 International Business Machines Corporation Inorganic seal for encapsulation of an organic layer and method for making the same
US5748091A (en) 1996-10-04 1998-05-05 Mcdonnell Douglas Corporation Fiber optic ice detector
US6048732A (en) 1996-10-16 2000-04-11 Board Of Regents, The University Of Texas System Receptor and method for citrate determination
JP2001504389A (ja) 1996-10-21 2001-04-03 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー ビーズを分配する装置と方法
US6083761A (en) * 1996-12-02 2000-07-04 Glaxo Wellcome Inc. Method and apparatus for transferring and combining reagents
US5779907A (en) * 1996-12-06 1998-07-14 Systems Research Laboratories, Inc. Magnetic microplate separator
US6245331B1 (en) * 1997-01-02 2001-06-12 New York Univ. Medical Center Early detection of mycobacterial disease
CA2389358C (en) * 1996-12-31 2008-07-15 Genometrix Incorporated Multiplexed molecular analysis apparatus and method
US6413786B1 (en) 1997-01-23 2002-07-02 Union Biometrica Technology Holdings, Inc. Binding assays using optical resonance of colloidal particles
US5827748A (en) * 1997-01-24 1998-10-27 The United States Of America As Represented By The Secretary Of The Navy Chemical sensor using two-dimensional lens array
US5981297A (en) 1997-02-05 1999-11-09 The United States Of America As Represented By The Secretary Of The Navy Biosensor using magnetically-detected label
US6037137A (en) * 1997-02-20 2000-03-14 Oncoimmunin, Inc. Fluorogenic peptides for the detection of protease activity
US6023540A (en) 1997-03-14 2000-02-08 Trustees Of Tufts College Fiber optic sensor with encoded microspheres
US6045579A (en) 1997-05-01 2000-04-04 Spinal Concepts, Inc. Adjustable height fusion device
US6406845B1 (en) 1997-05-05 2002-06-18 Trustees Of Tuft College Fiber optic biosensor for selectively detecting oligonucleotide species in a mixed fluid sample
US6171780B1 (en) 1997-06-02 2001-01-09 Aurora Biosciences Corporation Low fluorescence assay platforms and related methods for drug discovery
US6426050B1 (en) * 1997-05-16 2002-07-30 Aurora Biosciences Corporation Multi-well platforms, caddies, lids and combinations thereof
US5985120A (en) 1997-06-12 1999-11-16 University Of Massachusetts Rapid analysis of analyte solutions
US6002817A (en) 1997-09-29 1999-12-14 The Regents Of The University Of Michigan Optical sensors for the detection of nitric oxide
US7115884B1 (en) 1997-10-06 2006-10-03 Trustees Of Tufts College Self-encoding fiber optic sensor
US5922617A (en) 1997-11-12 1999-07-13 Functional Genetics, Inc. Rapid screening assay methods and devices
US5992820A (en) * 1997-11-19 1999-11-30 Sarnoff Corporation Flow control in microfluidics devices by controlled bubble formation
US6074616A (en) 1998-01-05 2000-06-13 Biosite Diagnostics, Inc. Media carrier for an assay device
ATE239801T1 (de) * 1998-01-22 2003-05-15 Luminex Corp Mikropartikel mit multiplen fluoreszenz-signalen
US6210910B1 (en) 1998-03-02 2001-04-03 Trustees Of Tufts College Optical fiber biosensor array comprising cell populations confined to microcavities
JP3944996B2 (ja) * 1998-03-05 2007-07-18 株式会社日立製作所 Dnaプローブアレー
JP3459770B2 (ja) * 1998-04-10 2003-10-27 キヤノン株式会社 画像読取装置および方法、記録媒体
DE19827754C1 (de) 1998-06-23 2000-02-10 Graffinity Pharm Design Gmbh Einrichtung für eine nahezu gleichzeitige Synthese einer Vielzahl von Proben
DE19825909C1 (de) 1998-06-10 1999-11-25 Graffinity Pharm Design Gmbh Reaktorträger mit mehreren Mikroprobenaufnahmekammern
US6692696B1 (en) * 1998-06-18 2004-02-17 ARETé ASSOCIATES Biosensor
US6908770B1 (en) * 1998-07-16 2005-06-21 Board Of Regents, The University Of Texas System Fluid based analysis of multiple analytes by a sensor array
GB9821573D0 (en) 1998-10-02 1998-11-25 Central Research Lab Ltd Method and apparatus for removing a substance from a container
US6601613B2 (en) * 1998-10-13 2003-08-05 Biomicro Systems, Inc. Fluid circuit components based upon passive fluid dynamics
US6136273A (en) * 1998-11-18 2000-10-24 Matrix Technologies Corporation Closure device for laboratory receptacles
US6151973A (en) 1999-01-29 2000-11-28 Glaxo Wellcome Inc. Bead picking apparatus and method
US6787368B1 (en) * 1999-03-02 2004-09-07 Helix Biopharma Corporation Biosensor method for detecting analytes in a liquid
CN1185492C (zh) 1999-03-15 2005-01-19 清华大学 可单点选通式微电磁单元阵列芯片、电磁生物芯片及应用
US6355431B1 (en) 1999-04-20 2002-03-12 Illumina, Inc. Detection of nucleic acid amplification reactions using bead arrays
US6410255B1 (en) * 1999-05-05 2002-06-25 Aurora Biosciences Corporation Optical probes and assays
US6485690B1 (en) * 1999-05-27 2002-11-26 Orchid Biosciences, Inc. Multiple fluid sample processor and system
US6258229B1 (en) * 1999-06-02 2001-07-10 Handani Winarta Disposable sub-microliter volume sensor and method of making
US6219566B1 (en) * 1999-07-13 2001-04-17 Photonics Research Ontario Method of measuring concentration of luminescent materials in turbid media
EP1204859B1 (de) * 1999-07-16 2006-11-22 The Board Of Regents, The University Of Texas System Verfahren und vorrichtung zur zuführung von proben zu einer chemischen sensormatrix
US7022517B1 (en) * 1999-07-16 2006-04-04 Board Of Regents, The University Of Texas System Method and apparatus for the delivery of samples to a chemical sensor array
US6411207B2 (en) * 1999-10-01 2002-06-25 Avaya Technology Corp. Personal alert device
US6682649B1 (en) * 1999-10-01 2004-01-27 Sophion Bioscience A/S Substrate and a method for determining and/or monitoring electrophysiological properties of ion channels
US6254830B1 (en) 1999-11-05 2001-07-03 The Board Of Governors For Higher Education, State Of Rhode Island And Providence Plantations Magnetic focusing immunosensor for the detection of pathogens
US6309889B1 (en) 1999-12-23 2001-10-30 Glaxo Wellcome Inc. Nano-grid micro reactor and methods
US7316899B2 (en) * 2000-01-31 2008-01-08 The Board Of Regents Of The University Of Texas System Portable sensor array system
US6514415B2 (en) * 2000-01-31 2003-02-04 Dexter Magnetic Technologies, Inc. Method and apparatus for magnetic separation of particles
US6591124B2 (en) * 2001-05-11 2003-07-08 The Procter & Gamble Company Portable interstitial fluid monitoring system
US8257967B2 (en) * 2002-04-26 2012-09-04 Board Of Regents, The University Of Texas System Method and system for the detection of cardiac risk factors
US8101431B2 (en) * 2004-02-27 2012-01-24 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems
US20060257991A1 (en) * 2004-02-27 2006-11-16 Mcdevitt John T Integration of fluids and reagents into self-contained cartridges containing particle-based sensor elements and membrane-based sensor elements
US8105849B2 (en) * 2004-02-27 2012-01-31 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements
US20090215646A1 (en) * 2005-07-01 2009-08-27 The Board Of Regents Of The University Of Texas Sy System and method of analyte detection using differential receptors

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US20110251075A1 (en) 2011-10-13
EP1255980A1 (de) 2002-11-13
US7316899B2 (en) 2008-01-08
AU2001233200A1 (en) 2001-08-07
US6649403B1 (en) 2003-11-18
WO2001055702A9 (en) 2002-10-24
WO2001055701A1 (en) 2001-08-02
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WO2001055952A2 (en) 2001-08-02
CA2401782A1 (en) 2001-08-02
AU2001236597A1 (en) 2001-08-07
US20030064422A1 (en) 2003-04-03
WO2001055952A8 (en) 2002-05-16
US20040053322A1 (en) 2004-03-18
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US20080219891A1 (en) 2008-09-11
DE60135092D1 (de) 2008-09-11
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WO2001055952A9 (en) 2002-01-10
US6713298B2 (en) 2004-03-30
AU2001238011A1 (en) 2001-08-07
WO2001055701A9 (en) 2002-10-31
AU2001234709A1 (en) 2001-08-07
EP2230314A1 (de) 2010-09-22
WO2001055702A1 (en) 2001-08-02
WO2001055703A9 (en) 2002-10-24
WO2001055704A1 (en) 2001-08-02
US20030186228A1 (en) 2003-10-02
US20050136548A1 (en) 2005-06-23
EP1255980B1 (de) 2008-07-30

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