ATE403444T1 - Durch röntgen- und/oder uv-strahlen aktivierbare partikel, deren herstellung und deren therapeutische oder diagnostische verwendung - Google Patents

Durch röntgen- und/oder uv-strahlen aktivierbare partikel, deren herstellung und deren therapeutische oder diagnostische verwendung

Info

Publication number
ATE403444T1
ATE403444T1 AT05769516T AT05769516T ATE403444T1 AT E403444 T1 ATE403444 T1 AT E403444T1 AT 05769516 T AT05769516 T AT 05769516T AT 05769516 T AT05769516 T AT 05769516T AT E403444 T1 ATE403444 T1 AT E403444T1
Authority
AT
Austria
Prior art keywords
rays
particles
production
therapeutic
relates
Prior art date
Application number
AT05769516T
Other languages
English (en)
Inventor
Laurent Levy
Jean-Francois Hochepied
Jeremy Balencie
Paras Prasad
Earl Bergey
Edouard Panak
Abdel Boussaha
Original Assignee
Nanobiotix
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanobiotix filed Critical Nanobiotix
Application granted granted Critical
Publication of ATE403444T1 publication Critical patent/ATE403444T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/062—Photodynamic therapy, i.e. excitation of an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0052—Thermotherapy; Hyperthermia; Magnetic induction; Induction heating therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0409—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is not a halogenated organic compound
    • A61K49/0414—Particles, beads, capsules or spheres
    • A61K49/0423—Nanoparticles, nanobeads, nanospheres, nanocapsules, i.e. having a size or diameter smaller than 1 micrometer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N13/00—Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0661—Radiation therapy using light characterised by the wavelength of light used ultraviolet
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1092—Details
    • A61N2005/1098—Enhancing the effect of the particle by an injected agent or implanted device

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nanotechnology (AREA)
  • Organic Chemistry (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Optics & Photonics (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Paints Or Removers (AREA)
AT05769516T 2004-05-10 2005-05-09 Durch röntgen- und/oder uv-strahlen aktivierbare partikel, deren herstellung und deren therapeutische oder diagnostische verwendung ATE403444T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0405036A FR2869803B1 (fr) 2004-05-10 2004-05-10 Particules activables, preparation et utilisations

Publications (1)

Publication Number Publication Date
ATE403444T1 true ATE403444T1 (de) 2008-08-15

Family

ID=34945762

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05769516T ATE403444T1 (de) 2004-05-10 2005-05-09 Durch röntgen- und/oder uv-strahlen aktivierbare partikel, deren herstellung und deren therapeutische oder diagnostische verwendung

Country Status (24)

Country Link
US (2) US9162079B2 (de)
EP (1) EP1744789B1 (de)
JP (1) JP5150251B2 (de)
KR (2) KR20120123731A (de)
CN (1) CN100592921C (de)
AT (1) ATE403444T1 (de)
AU (1) AU2005251499B2 (de)
BR (1) BRPI0510290B8 (de)
CA (1) CA2564197C (de)
CY (1) CY1108369T1 (de)
DE (1) DE602005008731D1 (de)
DK (1) DK1744789T3 (de)
EA (1) EA010246B1 (de)
ES (1) ES2312004T3 (de)
FR (1) FR2869803B1 (de)
HR (1) HRP20080534T3 (de)
IL (1) IL178877A (de)
MX (1) MXPA06013095A (de)
PL (1) PL1744789T3 (de)
PT (1) PT1744789E (de)
RS (1) RS50615B (de)
SI (1) SI1744789T1 (de)
WO (1) WO2005120590A1 (de)
ZA (1) ZA200610255B (de)

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FR2869803B1 (fr) 2004-05-10 2006-07-28 Nanobiotix Sarl Particules activables, preparation et utilisations
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US20070218049A1 (en) * 2006-02-02 2007-09-20 Wei Chen Nanoparticle based photodynamic therapy and methods of making and using same
WO2007122956A1 (ja) * 2006-03-24 2007-11-01 Toto Ltd. 酸化チタン複合体粒子、その分散液、およびそれらの製造方法
EP1852107A1 (de) * 2006-04-19 2007-11-07 Nanobiotix Zusammensetzungen enthaltend magnetische Nanopartikel sowie deren Verwendung
EP1920784A1 (de) * 2006-11-13 2008-05-14 Koninklijke Philips Electronics N.V. Strahlungssensibilisatoren in der Strahlentherapie und in der Bildgebung
US8951561B2 (en) 2007-08-06 2015-02-10 Duke University Methods and systems for treating cell proliferation disorders using plasmonics enhanced photospectral therapy (PEPST) and exciton-plasmon enhanced phototherapy (EPEP)
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US8376013B2 (en) 2008-03-11 2013-02-19 Duke University Plasmonic assisted systems and methods for interior energy-activation from an exterior source
US9488916B2 (en) 2007-04-08 2016-11-08 Immunolight, Llc. Interior energy-activation of photo-reactive species inside a medium or body
FR2922106B1 (fr) * 2007-10-16 2011-07-01 Univ Claude Bernard Lyon Utilisation de nanoparticules a base de lanthanides comme agents radiosensibilisants.
US8164074B2 (en) * 2007-10-18 2012-04-24 The Invention Science Fund I, Llc Ionizing-radiation-responsive compositions, methods, and systems
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US8168958B2 (en) * 2007-10-18 2012-05-01 The Invention Science Fund I, Llc Ionizing-radiation-responsive compositions, methods, and systems
US8684898B2 (en) * 2007-10-18 2014-04-01 The Invention Science Fund I Llc Ionizing-radiation-responsive compositions, methods, and systems
US20090104113A1 (en) * 2007-10-18 2009-04-23 Searete Llc Ionizing-radiation-responsive compositions, methods, and systems
US8227204B2 (en) * 2007-10-18 2012-07-24 The Invention Science Fund I, Llc Ionizing-radiation-responsive compositions, methods, and systems
US9557635B2 (en) * 2007-10-18 2017-01-31 Gearbox, Llc Ionizing-radiation-responsive compositions, methods, and systems
US8529426B2 (en) * 2007-10-18 2013-09-10 The Invention Science Fund I Llc Ionizing-radiation-responsive compositions, methods, and systems
US9907976B2 (en) 2011-07-08 2018-03-06 Immunolight, Llc Phosphors and scintillators for light stimulation within a medium
CA2906990A1 (en) * 2008-04-04 2009-10-08 Duke University Non-invasive systems and methods for in-situ photobiomodulation
EP2130553A1 (de) 2008-06-05 2009-12-09 Nanobiotix Anorganische Nanopartikel mit hoher Dichte, um in-vivo Zellen zu zerstören
US8770203B2 (en) 2008-07-14 2014-07-08 Immunolight, Llc. Advanced methods and systems for treating cell proliferation disorders
BRPI0911715A2 (pt) 2008-07-31 2019-09-24 Alma Mater Studiorum - Universita' Di Bologna partículas ativas para aplicações bio-analíticas e métodos para sua preparação.
WO2010123993A1 (en) * 2009-04-21 2010-10-28 Tuan Vo-Dinh Non-invasive energy upconversion methods and systems for in-situ photobiomodulation
CN102870235B (zh) * 2009-11-10 2016-11-23 免疫之光有限责任公司 用于从包括用于上变频的射频、微波能量和磁感应源的各种能量源产生发射光的上下变频系统
GB0921596D0 (en) 2009-12-09 2010-01-27 Isis Innovation Particles for the treatment of cancer in combination with radiotherapy
WO2011140469A1 (en) 2010-05-06 2011-11-10 Zakaryae Fathi Adhesive bonding composition and method of use
US9572880B2 (en) 2010-08-27 2017-02-21 Sienna Biopharmaceuticals, Inc. Ultrasound delivery of nanoparticles
PT3213738T (pt) 2010-08-27 2020-03-31 Sebacia Inc Composições e métodos para modulação térmica direcionada
US9116246B2 (en) * 2011-04-07 2015-08-25 Stc.Unm Thermal neutron detectors based on gadolinium-containing nanoscintillators
JPWO2012153820A1 (ja) * 2011-05-12 2014-07-31 コニカミノルタ株式会社 Ｘ線吸収蛍光ナノ粒子
WO2013009701A2 (en) 2011-07-08 2013-01-17 The University Of North Carolina At Chapel Hill Metal bisphosphonate nanoparticles for anti-cancer therapy and imaging and for treating bone disorders
WO2013035739A1 (ja) * 2011-09-05 2013-03-14 株式会社Ihi 温熱治療用材料、温熱治療用システム及び温熱治療方法
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US20160136304A1 (en) * 2013-06-20 2016-05-19 Nanobiotix Compositions and methods for use in oncology
EA201690050A1 (ru) * 2013-06-20 2016-05-31 Нанобиотикс Композиции и способы для применения в медицинской диагностике
FR3018451A1 (fr) * 2014-03-13 2015-09-18 Chromalys Nanoparticules pour leur utilisation dans la detection de tumeurs mobiles
US10780164B2 (en) * 2014-04-03 2020-09-22 The Governing Council Of The University Of Toronto Multifunctional nanoparticle compositions and uses thereof
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US10806694B2 (en) 2014-10-14 2020-10-20 The University Of Chicago Nanoparticles for photodynamic therapy, X-ray induced photodynamic therapy, radiotherapy, radiodynamic therapy, chemotherapy, immunotherapy, and any combination thereof
US20180008733A1 (en) * 2015-01-08 2018-01-11 Purdue Research Foundation Non-toxic formulations of radio-luminescent nanoparticles for use as cancer radio-sensitizing agents
UA124572C2 (uk) 2015-05-28 2021-10-13 Нанобіотікс Наночастинки для застосування як терапевтичної вакцини
US9770688B2 (en) * 2015-10-22 2017-09-26 King Fahd University Of Petroleum And Minerals Si—Y nanocomposite membrane and methods of making and use thereof
EP3439666A4 (de) 2016-05-20 2019-12-11 The University of Chicago Nanopartikel zur chemotherapie, gezielte therapie, photodynamische therapie, immuntherapie und alle kombinationen davon
CN110382010A (zh) 2016-12-08 2019-10-25 布里格姆妇女医院 铋-钆纳米颗粒
US10283476B2 (en) 2017-03-15 2019-05-07 Immunolight, Llc. Adhesive bonding composition and electronic components prepared from the same
EP3638367A4 (de) 2017-08-02 2021-07-21 The University of Chicago Nanoskalige metallorganische schichten und metallorganische nanoplatten für die röntgenstrahlinduzierte photodynamische therapie, strahlentherapie, dynamische strahlentherapie, chemotherapie, immuntherapie und eine beliebige kombination davon
EP3849613A2 (de) 2018-06-01 2021-07-21 Tae Life Sciences Biologisch abbaubare nanoträger zur neutroneneinfangtherapie und verfahren dafür
US20240000940A1 (en) * 2020-12-01 2024-01-04 Nanobiotix S.A. Porous, high-z and carbon-free particles as radioenhancers
CN112655715A (zh) * 2020-12-25 2021-04-16 杭州甜蜜按钮科技有限公司 一种哺乳期羊舍专用消毒剂的制备方法
JP2024511277A (ja) 2021-02-19 2024-03-13 メビオン・メディカル・システムズ・インコーポレーテッド 粒子線治療システムのためのガントリー
EP4595983A1 (de) 2024-02-05 2025-08-06 BXTA Nanotherapy Limited Mit einem stabilisierungsmittel und einem zielmittel funktionalisierte nanopartikel

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US20070218049A1 (en) * 2006-02-02 2007-09-20 Wei Chen Nanoparticle based photodynamic therapy and methods of making and using same

Also Published As

Publication number Publication date
KR101234334B1 (ko) 2013-02-18
US9433800B2 (en) 2016-09-06
ES2312004T3 (es) 2009-02-16
IL178877A (en) 2010-12-30
EP1744789B1 (de) 2008-08-06
CA2564197C (fr) 2013-05-07
US9162079B2 (en) 2015-10-20
IL178877A0 (en) 2007-03-08
BRPI0510290A8 (pt) 2019-01-02
FR2869803B1 (fr) 2006-07-28
AU2005251499A1 (en) 2005-12-22
SI1744789T1 (sl) 2008-10-31
MXPA06013095A (es) 2007-04-27
DE602005008731D1 (de) 2008-09-18
PT1744789E (pt) 2008-11-04
JP5150251B2 (ja) 2013-02-20
CN1950111A (zh) 2007-04-18
CY1108369T1 (el) 2014-02-12
AU2005251499B2 (en) 2010-06-10
PL1744789T3 (pl) 2009-01-30
BRPI0510290A (pt) 2007-10-30
EA010246B1 (ru) 2008-06-30
HK1099508A1 (zh) 2007-08-17
FR2869803A1 (fr) 2005-11-11
BRPI0510290B1 (pt) 2021-06-01
DK1744789T3 (da) 2008-12-08
ZA200610255B (en) 2008-09-25
US20070217996A1 (en) 2007-09-20
KR20120123731A (ko) 2012-11-09
BRPI0510290B8 (pt) 2021-10-19
RS50615B (sr) 2010-06-30
KR20070014172A (ko) 2007-01-31
HRP20080534T3 (en) 2008-11-30
CA2564197A1 (fr) 2005-12-22
EP1744789A1 (de) 2007-01-24
EA200602077A1 (ru) 2007-04-27
US20150238775A1 (en) 2015-08-27
JP2007536356A (ja) 2007-12-13
WO2005120590A1 (fr) 2005-12-22
CN100592921C (zh) 2010-03-03

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