ATE403496T1 - Probenablageverfahren und -system - Google Patents
Probenablageverfahren und -systemInfo
- Publication number
- ATE403496T1 ATE403496T1 AT02718848T AT02718848T ATE403496T1 AT E403496 T1 ATE403496 T1 AT E403496T1 AT 02718848 T AT02718848 T AT 02718848T AT 02718848 T AT02718848 T AT 02718848T AT E403496 T1 ATE403496 T1 AT E403496T1
- Authority
- AT
- Austria
- Prior art keywords
- sample
- liquid
- sample plate
- droplet
- molecules
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0241—Drop counters; Drop formers
- B01L3/0268—Drop counters; Drop formers using pulse dispensing or spraying, eg. inkjet type, piezo actuated ejection of droplets from capillaries
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00364—Pipettes
- B01J2219/00367—Pipettes capillary
- B01J2219/00369—Pipettes capillary in multiple or parallel arrangements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00364—Pipettes
- B01J2219/00371—Pipettes comprising electrodes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00653—Making arrays on substantially continuous surfaces the compounds being bound to electrodes embedded in or on the solid supports
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00686—Automatic
- B01J2219/00691—Automatic using robots
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
- B01L2300/0838—Capillaries
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/02—Drop detachment mechanisms of single droplets from nozzles or pins
- B01L2400/027—Drop detachment mechanisms of single droplets from nozzles or pins electrostatic forces between substrate and tip
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Landscapes
- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Sampling And Sample Adjustment (AREA)
- Electron Tubes For Measurement (AREA)
- Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
- Stabilization Of Oscillater, Synchronisation, Frequency Synthesizers (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/765,207 US6918309B2 (en) | 2001-01-17 | 2001-01-17 | Sample deposition method and system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE403496T1 true ATE403496T1 (de) | 2008-08-15 |
Family
ID=25072933
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02718848T ATE403496T1 (de) | 2001-01-17 | 2002-01-17 | Probenablageverfahren und -system |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US6918309B2 (de) |
| EP (1) | EP1358012B1 (de) |
| JP (1) | JP4162207B2 (de) |
| AT (1) | ATE403496T1 (de) |
| AU (1) | AU2007221973B2 (de) |
| CA (1) | CA2434305C (de) |
| DE (1) | DE60228049D1 (de) |
| WO (1) | WO2002062475A1 (de) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7470547B2 (en) * | 2003-07-31 | 2008-12-30 | Biodot, Inc. | Methods and systems for dispensing sub-microfluidic drops |
| JP2003507715A (ja) * | 1999-08-13 | 2003-02-25 | カーティージャン テクノロジーズ、 インコーポレイテッド | 液体試料取扱い装置 |
| US6918309B2 (en) * | 2001-01-17 | 2005-07-19 | Irm Llc | Sample deposition method and system |
| AU2002362446A1 (en) * | 2001-10-03 | 2003-04-14 | Kin Chiu Ng | Apparatus and method for fabricating high density microarrays and applications thereof |
| DE10162188A1 (de) * | 2001-12-17 | 2003-06-18 | Sunyx Surface Nanotechnologies | Hydrophobe Oberfläche mit einer Vielzahl von Elektroden |
| FR2843048B1 (fr) * | 2002-08-01 | 2004-09-24 | Commissariat Energie Atomique | Dispositif d'injection et de melange de micro-gouttes liquides. |
| GB0226160D0 (en) * | 2002-11-08 | 2002-12-18 | Diagnoswiss Sa | Apparatus for dispensing a sample in electrospray mass spectrometers |
| US7332347B2 (en) | 2003-04-14 | 2008-02-19 | Liang Li | Apparatus and method for concentrating and collecting analytes from a flowing liquid stream |
| US6891156B2 (en) * | 2003-04-30 | 2005-05-10 | Perkin Elmer Instruments Llc | Sample plate for matrix-assisted laser desorption and ionization mass spectrometry |
| US7858387B2 (en) * | 2003-04-30 | 2010-12-28 | Perkinelmer Health Sciences, Inc. | Method of scanning a sample plate surface mask in an area adjacent to a conductive area using matrix-assisted laser desorption and ionization mass spectrometry |
| US7294309B1 (en) * | 2003-05-15 | 2007-11-13 | Takeda San Diego, Inc. | Small volume liquid handling apparatus and method |
| US7138050B2 (en) | 2003-05-29 | 2006-11-21 | Shimadzu Corporation | Fractionating/collecting device of liquid chromatograph |
| WO2004111610A2 (en) | 2003-06-12 | 2004-12-23 | Accupath Diagnostic Laboratories, Inc. | Method and system for the analysis of high density cells samples |
| JP4174599B2 (ja) * | 2003-07-08 | 2008-11-05 | 株式会社島津製作所 | 高速液体クロマトグラフの分画装置 |
| DE102004062280A1 (de) * | 2003-12-29 | 2005-07-28 | Siemens Ag | Verfahren und Vorrichtung zum Dispensieren von Flüssigkeiten im Mikroraster |
| US7438859B2 (en) * | 2003-12-31 | 2008-10-21 | Protedyne Corporation | Method and apparatus for laser impulse sample deposition |
| KR100552705B1 (ko) * | 2004-01-07 | 2006-02-20 | 삼성전자주식회사 | 전기수력학적(Electrohydrodynamic)현상을 이용하여 기판 상에 생체분자를 프린팅하는 장치및 그 프린팅 방법 |
| US7335897B2 (en) * | 2004-03-30 | 2008-02-26 | Purdue Research Foundation | Method and system for desorption electrospray ionization |
| US7317187B2 (en) | 2004-05-20 | 2008-01-08 | Davidson William R | Frontal affinity chromatography/MALDI tandem mass spectrometry |
| ATE485888T1 (de) | 2004-08-26 | 2010-11-15 | Life Technologies Corp | Elektrobenetzende abgabevorrichtungen und dazugehörige verfahren |
| JP4306729B2 (ja) | 2004-08-30 | 2009-08-05 | 株式会社島津製作所 | 試料前処理装置とそれに用いるプローブ |
| JP4765295B2 (ja) * | 2004-10-27 | 2011-09-07 | 株式会社島津製作所 | 分析機器管理装置 |
| EP1853906A4 (de) * | 2005-02-08 | 2010-03-17 | Mds Inc Dbt Mds Sciex Division | Verfahren und vorrichtung zur probenablage |
| CA2496481A1 (en) * | 2005-02-08 | 2006-08-09 | Mds Inc., Doing Business Through It's Mds Sciex Division | Method and apparatus for sample deposition |
| WO2006084376A1 (en) * | 2005-02-09 | 2006-08-17 | The University Of British Columbia | Sub-microlitre electrostatic dispenser |
| US20060210443A1 (en) | 2005-03-14 | 2006-09-21 | Stearns Richard G | Avoidance of bouncing and splashing in droplet-based fluid transport |
| KR100624467B1 (ko) * | 2005-05-13 | 2006-09-15 | 삼성전자주식회사 | 전기수력학적(electrohydrodynamic)현상을 이용하여 기판 상에 생체분자를 프린팅하는 장치 |
| US20060266941A1 (en) * | 2005-05-26 | 2006-11-30 | Vestal Marvin L | Method and apparatus for interfacing separations techniques to MALDI-TOF mass spectrometry |
| KR100668343B1 (ko) * | 2005-08-12 | 2007-01-12 | 삼성전자주식회사 | 전기전하집중 현상을 이용하여 기판 상에 생체분자 액적을프린팅하는 장치 및 전기전하집중 현상을 이용하여인쇄용지 또는 인쇄기판 상에 잉크를 프린팅하는 장치 |
| US8820265B2 (en) | 2005-12-06 | 2014-09-02 | Opertech Bio, Inc. | High-throughput operant sensory discrimination apparatus and method |
| US7544933B2 (en) * | 2006-01-17 | 2009-06-09 | Purdue Research Foundation | Method and system for desorption atmospheric pressure chemical ionization |
| KR101217550B1 (ko) * | 2006-01-26 | 2013-01-02 | 삼성전자주식회사 | 방사형 전기삼투 유동을 이용한 증발하는 액적 내의 입자분포 제어 장치 |
| KR100723427B1 (ko) * | 2006-05-12 | 2007-05-30 | 삼성전자주식회사 | 기판상에 생체분자 액적을 프린팅하는 장치 및 방법 |
| EP2136911A2 (de) | 2007-01-19 | 2009-12-30 | Biodot, Inc. | Systeme und verfahren für hochgeschwindigkeitsarraydruck und -hybridisierung |
| US7663100B2 (en) * | 2007-05-01 | 2010-02-16 | Virgin Instruments Corporation | Reversed geometry MALDI TOF |
| US7589319B2 (en) | 2007-05-01 | 2009-09-15 | Virgin Instruments Corporation | Reflector TOF with high resolution and mass accuracy for peptides and small molecules |
| US7838824B2 (en) * | 2007-05-01 | 2010-11-23 | Virgin Instruments Corporation | TOF-TOF with high resolution precursor selection and multiplexed MS-MS |
| US7564026B2 (en) * | 2007-05-01 | 2009-07-21 | Virgin Instruments Corporation | Linear TOF geometry for high sensitivity at high mass |
| US7564028B2 (en) * | 2007-05-01 | 2009-07-21 | Virgin Instruments Corporation | Vacuum housing system for MALDI-TOF mass spectrometry |
| US7667195B2 (en) * | 2007-05-01 | 2010-02-23 | Virgin Instruments Corporation | High performance low cost MALDI MS-MS |
| US20090205581A1 (en) * | 2008-02-15 | 2009-08-20 | Redpoint Bio Corporation | High-throughput operant sensory discrimination apparatus and method |
| EP2157599A1 (de) * | 2008-08-21 | 2010-02-24 | Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO | Verfahren und Vorrichtung zur Identifikation biologischer Materialien |
| JP5636614B2 (ja) * | 2010-09-02 | 2014-12-10 | 学校法人立教学院 | Lc−maldiで得られたデータの比較解析方法 |
| CN103429348B (zh) | 2011-01-21 | 2016-03-09 | 拜奥-多特公司 | 具有纵向变换器和可替换毛细管的压电分配器 |
| EP2805143A4 (de) * | 2012-01-17 | 2015-08-12 | Scripps Research Inst | Vorrichtung und verfahren zur herstellung von proben für die elektronenmikroskopie |
| WO2013109405A1 (en) * | 2012-01-17 | 2013-07-25 | The Scripps Research Institute | Preparation of specimen arrays on an em grid |
| CN104769410B (zh) | 2012-11-06 | 2018-07-27 | 拜奥-多特公司 | 用于核型分析的细胞样本的受控印刷 |
| JP2018513984A (ja) * | 2015-04-06 | 2018-05-31 | ナノサイトミクス,エルエルシー | 自動化標本堆積システム及び関連する方法 |
| US11460383B2 (en) | 2016-06-16 | 2022-10-04 | Nanocytomics, LLC | Automated staining system |
| KR102180624B1 (ko) * | 2017-10-11 | 2020-11-18 | 주식회사 엘지화학 | Maldi 질량분석법을 이용한 고분자의 정량분석방법 및 고분자 정량분석을 위한 maldi 질량분석용 시편의 제조방법 |
| KR102121644B1 (ko) * | 2017-11-23 | 2020-06-10 | 주식회사 엘지화학 | Maldi 질량분석법을 이용한 고분자의 상대 정량분석방법 |
| CN110075933B (zh) * | 2018-01-25 | 2022-05-13 | 北京致雨生物科技有限公司 | 微液滴生成装置、系统及生成方法 |
| KR102362175B1 (ko) * | 2018-08-30 | 2022-02-11 | 주식회사 엘지화학 | Maldi 질량 분석을 이용한 고분자의 상대적 정량분석방법 |
| WO2020045821A1 (ko) * | 2018-08-30 | 2020-03-05 | 주식회사 엘지화학 | Maldi 질량 분석을 이용한 고분자의 상대적 정량분석방법 |
| KR102362170B1 (ko) | 2019-04-08 | 2022-02-11 | 주식회사 엘지화학 | Maldi 질량분석을 이용한 고분자의 상대적 정량분석방법 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3476291A (en) * | 1968-06-13 | 1969-11-04 | Berkeley Scient Lab Inc | Method and apparatus for dispensing measured quantities of liquids |
| US3661304A (en) * | 1970-08-03 | 1972-05-09 | Mead Corp | Pressure impulse apparatus for initiating formation of fluid drops |
| US3941312A (en) * | 1973-11-23 | 1976-03-02 | Research and Development Laboratories of Ohno Company Limited | Ink jet nozzle for use in a recording unit |
| FR2463920A1 (fr) * | 1979-08-17 | 1981-02-27 | Commissariat Energie Atomique | Dispositif microdoseur de liquides |
| US4867947A (en) * | 1986-09-08 | 1989-09-19 | Sepragen Corporation | Interface for liquid chromatograph-mass spectrometer |
| US5045172A (en) * | 1987-11-25 | 1991-09-03 | Princeton Biochemicals, Inc. | Capillary electrophoresis apparatus |
| US5232565A (en) * | 1988-09-27 | 1993-08-03 | The Board Of Trustees Of The Leland Standford Junior University | Capillary electrophoretic system |
| US5750015A (en) * | 1990-02-28 | 1998-05-12 | Soane Biosciences | Method and device for moving molecules by the application of a plurality of electrical fields |
| CA2124087C (en) * | 1991-11-22 | 2002-10-01 | James L. Winkler | Combinatorial strategies for polymer synthesis |
| DE4229005A1 (de) * | 1992-08-31 | 1994-03-03 | Linde Ag | Dosierung flüssiger Substanzen |
| JPH07275690A (ja) * | 1994-04-05 | 1995-10-24 | Mitsubishi Electric Corp | 浮遊装置 |
| US5985356A (en) * | 1994-10-18 | 1999-11-16 | The Regents Of The University Of California | Combinatorial synthesis of novel materials |
| SE9502251D0 (sv) * | 1995-06-21 | 1995-06-21 | Pharmacia Ab | Flow-through sampling cell and use thereof |
| US5630925A (en) * | 1995-07-13 | 1997-05-20 | Beckman Instruments, Inc. | Capillary electrophoresis using a conductive capillary tube |
| US5879949A (en) * | 1995-11-22 | 1999-03-09 | Board Of Supervisors Of Louisiana State University & Agricultural And Mechanical College | Apparatus and method for rapid on-line electrochemistry and mass spectrometry |
| CN1329729C (zh) * | 1996-06-28 | 2007-08-01 | 卡钳生命科学股份有限公司 | 微流体系统 |
| US5916524A (en) * | 1997-07-23 | 1999-06-29 | Bio-Dot, Inc. | Dispensing apparatus having improved dynamic range |
| AU744879B2 (en) * | 1997-09-19 | 2002-03-07 | Aclara Biosciences, Inc. | Apparatus and method for transferring liquids |
| US6074725A (en) * | 1997-12-10 | 2000-06-13 | Caliper Technologies Corp. | Fabrication of microfluidic circuits by printing techniques |
| DE19754978C2 (de) * | 1997-12-11 | 2000-07-13 | Bruker Daltonik Gmbh | Probenträger für die MALDI-Massenspektrometrie nebst Verfahren zur Herstellung der Platten und zum Aufbringen der Proben |
| US5969350A (en) * | 1998-03-17 | 1999-10-19 | Comstock, Inc. | Maldi/LDI time-of-flight mass spectrometer |
| US6191418B1 (en) * | 1998-03-27 | 2001-02-20 | Synsorb Biotech, Inc. | Device for delivery of multiple liquid sample streams to a mass spectrometer |
| US6132685A (en) * | 1998-08-10 | 2000-10-17 | Caliper Technologies Corporation | High throughput microfluidic systems and methods |
| US6162341A (en) * | 1998-09-11 | 2000-12-19 | The Perkin-Elmer Corporation | Multi-channel capillary electrophoresis device including sheath-flow cuvette and replacable capillary array |
| US6132582A (en) * | 1998-09-14 | 2000-10-17 | The Perkin-Elmer Corporation | Sample handling system for a multi-channel capillary electrophoresis device |
| US6103199A (en) * | 1998-09-15 | 2000-08-15 | Aclara Biosciences, Inc. | Capillary electroflow apparatus and method |
| CN100525876C (zh) * | 1998-09-17 | 2009-08-12 | 阿德文生物系统公司 | 产生液体电喷射的方法 |
| US6149787A (en) * | 1998-10-14 | 2000-11-21 | Caliper Technologies Corp. | External material accession systems and methods |
| US6149815A (en) * | 1999-11-23 | 2000-11-21 | Sauter; Andrew D. | Precise electrokinetic delivery of minute volumes of liquid(s) |
| EP1246698B1 (de) * | 2000-01-06 | 2006-09-20 | Caliper Life Sciences, Inc. | Vorrichtungen und verfahren für hochdurchsatz-probenentnahme und analyse |
| WO2001071311A2 (en) * | 2000-03-17 | 2001-09-27 | Nanostream, Inc. | Electrostatic systems and methods for dispensing droplets |
| US6918309B2 (en) * | 2001-01-17 | 2005-07-19 | Irm Llc | Sample deposition method and system |
| US6657191B2 (en) * | 2001-03-02 | 2003-12-02 | Bruker Daltonics Inc. | Means and method for multiplexing sprays in an electrospray ionization source |
-
2001
- 2001-01-17 US US09/765,207 patent/US6918309B2/en not_active Expired - Fee Related
-
2002
- 2002-01-17 EP EP02718848A patent/EP1358012B1/de not_active Expired - Lifetime
- 2002-01-17 CA CA002434305A patent/CA2434305C/en not_active Expired - Fee Related
- 2002-01-17 JP JP2002562474A patent/JP4162207B2/ja not_active Expired - Fee Related
- 2002-01-17 AT AT02718848T patent/ATE403496T1/de not_active IP Right Cessation
- 2002-01-17 WO PCT/US2002/001536 patent/WO2002062475A1/en not_active Ceased
- 2002-01-17 DE DE60228049T patent/DE60228049D1/de not_active Expired - Lifetime
-
2005
- 2005-06-20 US US11/160,350 patent/US7578206B2/en not_active Expired - Fee Related
-
2007
- 2007-10-12 AU AU2007221973A patent/AU2007221973B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP1358012A4 (de) | 2006-04-05 |
| US7578206B2 (en) | 2009-08-25 |
| AU2007221973B2 (en) | 2009-12-10 |
| CA2434305A1 (en) | 2002-08-15 |
| EP1358012B1 (de) | 2008-08-06 |
| JP2004529325A (ja) | 2004-09-24 |
| WO2002062475A1 (en) | 2002-08-15 |
| DE60228049D1 (de) | 2008-09-18 |
| EP1358012A1 (de) | 2003-11-05 |
| US6918309B2 (en) | 2005-07-19 |
| WO2002062475B1 (en) | 2002-11-21 |
| US20050232823A1 (en) | 2005-10-20 |
| US20020092366A1 (en) | 2002-07-18 |
| CA2434305C (en) | 2010-03-09 |
| JP4162207B2 (ja) | 2008-10-08 |
| AU2007221973A1 (en) | 2007-11-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE403496T1 (de) | Probenablageverfahren und -system | |
| US7516714B2 (en) | Immobilizing device | |
| Otsuka et al. | Scanning probe electrospray ionization for ambient mass spectrometry | |
| WO2008098236A3 (en) | Droplet actuator devices and methods employing magnetic beads | |
| Jin et al. | Swan probe: a nanoliter-scale and high-throughput sampling interface for coupling electrospray ionization mass spectrometry with microfluidic droplet array and multiwell plate | |
| WO1999030168A1 (de) | Vorrichtung und verfahren zur elektrisch ausgelösten mikrotropfenabgabe mit einem dispensierkopf | |
| KR960025997A (ko) | 전자 방출 소자, 전자 소스 기판, 전자 소스, 디스플레이 패널 및 화상 형성 장치, 및 그 제조방법 | |
| US20030119193A1 (en) | System and method for high throughput screening of droplets | |
| BR9811006A (pt) | Sequência de dna, cassete de expressão, uso do mesmo, processo para transformar uma planta, planta com um elevado teor em vitamina e, processo para gerar plantas com um elevado teor em vitamina e e para gerar plantas com elevada resistência a inibidores de hppd, sistema de teste, subtância herbicamente ativa, uso de uma planta, e, planta com elevada resistência a inibidores de hppd | |
| ATE374259T1 (de) | Herstellung von matrizen aus polynukleotiden | |
| WO2001079849A3 (en) | Protein expression system arrays and use in biological screening | |
| ES2173670T3 (es) | Procedimiento de identificacion de acidos nucleicos mediante espectrometria de masas laser de desorcion/ionizacion asistidas por matriz. | |
| WO2005094389A3 (en) | Method and system for desorption electrospray ionization | |
| WO2007075488A3 (en) | System and method for scientific information knowledge management | |
| Barreiro-Lage et al. | “Smart Decomposition” of cyclic Alanine-Alanine dipeptide by VUV radiation: A seed for the synthesis of biologically relevant species | |
| DE50312887D1 (de) | Kontinuierliches verfahren zur gewinnung von butenen aus einem c4-schnitt | |
| ATE354863T1 (de) | Magnetronsputtereinrichtung, zylinderkathode und verfahren zur aufbringung von dünnen mehrkomponentenschichten auf einem substrat | |
| Hartner et al. | Coupling droplet microfluidics with ion mobility spectrometry for monitoring chemical conversions at nanoliter scale | |
| US9396916B2 (en) | Electrokinetically controlled calibrant delivery | |
| EP0966021A3 (de) | Vorrichtung zum Beschichten von Substraten in einer Vakuumkammer | |
| US20060110833A1 (en) | Method and apparatus for coupling an analyte supply to an electrodynamic droplet processor | |
| AU2003300509A1 (en) | Arrays of electrodes coated with molecules and their production | |
| FR2857451B1 (fr) | Procede et dispositif pour l'analyse de milieux reactionnels vivants | |
| Sahraeian et al. | High-throughput nanoliter sampling and direct analysis of biological fluids using droplet imbibition mass spectrometry | |
| ATE298272T1 (de) | Elektrostatisch erregtes beschichtungsverfahren und vorrichtung mit fokussiertem elektrodenfeld |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |