ATE403496T1 - Probenablageverfahren und -system - Google Patents

Probenablageverfahren und -system

Info

Publication number
ATE403496T1
ATE403496T1 AT02718848T AT02718848T ATE403496T1 AT E403496 T1 ATE403496 T1 AT E403496T1 AT 02718848 T AT02718848 T AT 02718848T AT 02718848 T AT02718848 T AT 02718848T AT E403496 T1 ATE403496 T1 AT E403496T1
Authority
AT
Austria
Prior art keywords
sample
liquid
sample plate
droplet
molecules
Prior art date
Application number
AT02718848T
Other languages
English (en)
Inventor
Ansgar Brock
Christopher Shaw
Robert Downs
Original Assignee
Irm Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Irm Llc filed Critical Irm Llc
Application granted granted Critical
Publication of ATE403496T1 publication Critical patent/ATE403496T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0241—Drop counters; Drop formers
    • B01L3/0268—Drop counters; Drop formers using pulse dispensing or spraying, eg. inkjet type, piezo actuated ejection of droplets from capillaries
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B01J2219/00364—Pipettes
    • B01J2219/00367—Pipettes capillary
    • B01J2219/00369—Pipettes capillary in multiple or parallel arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B01J2219/00364—Pipettes
    • B01J2219/00371—Pipettes comprising electrodes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00653—Making arrays on substantially continuous surfaces the compounds being bound to electrodes embedded in or on the solid supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00686—Automatic
    • B01J2219/00691—Automatic using robots
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
    • B01L2300/0838—Capillaries
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/02—Drop detachment mechanisms of single droplets from nozzles or pins
    • B01L2400/027—Drop detachment mechanisms of single droplets from nozzles or pins electrostatic forces between substrate and tip
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer

Landscapes

  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Stabilization Of Oscillater, Synchronisation, Frequency Synthesizers (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Electron Tubes For Measurement (AREA)
AT02718848T 2001-01-17 2002-01-17 Probenablageverfahren und -system ATE403496T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/765,207 US6918309B2 (en) 2001-01-17 2001-01-17 Sample deposition method and system

Publications (1)

Publication Number Publication Date
ATE403496T1 true ATE403496T1 (de) 2008-08-15

Family

ID=25072933

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02718848T ATE403496T1 (de) 2001-01-17 2002-01-17 Probenablageverfahren und -system

Country Status (8)

Country Link
US (2) US6918309B2 (de)
EP (1) EP1358012B1 (de)
JP (1) JP4162207B2 (de)
AT (1) ATE403496T1 (de)
AU (1) AU2007221973B2 (de)
CA (1) CA2434305C (de)
DE (1) DE60228049D1 (de)
WO (1) WO2002062475A1 (de)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7470547B2 (en) * 2003-07-31 2008-12-30 Biodot, Inc. Methods and systems for dispensing sub-microfluidic drops
JP2003507715A (ja) * 1999-08-13 2003-02-25 カーティージャン テクノロジーズ、 インコーポレイテッド 液体試料取扱い装置
US6918309B2 (en) * 2001-01-17 2005-07-19 Irm Llc Sample deposition method and system
US20030148538A1 (en) * 2001-10-03 2003-08-07 Ng Kin Chiu Apparatus and method for fabricating high density microarrays and applications thereof
DE10162188A1 (de) * 2001-12-17 2003-06-18 Sunyx Surface Nanotechnologies Hydrophobe Oberfläche mit einer Vielzahl von Elektroden
FR2843048B1 (fr) * 2002-08-01 2004-09-24 Commissariat Energie Atomique Dispositif d'injection et de melange de micro-gouttes liquides.
GB0226160D0 (en) * 2002-11-08 2002-12-18 Diagnoswiss Sa Apparatus for dispensing a sample in electrospray mass spectrometers
US7332347B2 (en) 2003-04-14 2008-02-19 Liang Li Apparatus and method for concentrating and collecting analytes from a flowing liquid stream
US6891156B2 (en) * 2003-04-30 2005-05-10 Perkin Elmer Instruments Llc Sample plate for matrix-assisted laser desorption and ionization mass spectrometry
US7858387B2 (en) * 2003-04-30 2010-12-28 Perkinelmer Health Sciences, Inc. Method of scanning a sample plate surface mask in an area adjacent to a conductive area using matrix-assisted laser desorption and ionization mass spectrometry
US7294309B1 (en) * 2003-05-15 2007-11-13 Takeda San Diego, Inc. Small volume liquid handling apparatus and method
US7138050B2 (en) 2003-05-29 2006-11-21 Shimadzu Corporation Fractionating/collecting device of liquid chromatograph
CA2529016A1 (en) 2003-06-12 2004-12-23 Accupath Diagnostic Laboratories, Inc. Method and system for the analysis of high density cells samples
JP4174599B2 (ja) * 2003-07-08 2008-11-05 株式会社島津製作所 高速液体クロマトグラフの分画装置
DE102004062280A1 (de) * 2003-12-29 2005-07-28 Siemens Ag Verfahren und Vorrichtung zum Dispensieren von Flüssigkeiten im Mikroraster
US7438859B2 (en) * 2003-12-31 2008-10-21 Protedyne Corporation Method and apparatus for laser impulse sample deposition
KR100552705B1 (ko) * 2004-01-07 2006-02-20 삼성전자주식회사 전기수력학적(Ｅｌｅｃｔｒｏｈｙｄｒｏｄｙｎａｍｉｃ)현상을 이용하여 기판 상에 생체분자를 프린팅하는 장치및 그 프린팅 방법
US7335897B2 (en) 2004-03-30 2008-02-26 Purdue Research Foundation Method and system for desorption electrospray ionization
US7317187B2 (en) 2004-05-20 2008-01-08 Davidson William R Frontal affinity chromatography/MALDI tandem mass spectrometry
EP1789195B1 (de) 2004-08-26 2010-10-27 Life Technologies Corporation Elektrobenetzende abgabevorrichtungen und dazugehörige verfahren
JP4306729B2 (ja) 2004-08-30 2009-08-05 株式会社島津製作所 試料前処理装置とそれに用いるプローブ
JP4765295B2 (ja) * 2004-10-27 2011-09-07 株式会社島津製作所 分析機器管理装置
CA2496481A1 (en) * 2005-02-08 2006-08-09 Mds Inc., Doing Business Through It's Mds Sciex Division Method and apparatus for sample deposition
JP2008530521A (ja) * 2005-02-08 2008-08-07 エムディーエス インコーポレイテッド ドゥーイング ビジネス スルー イッツ エムディーエス サイエックス ディヴィジョン サンプルの沈着の方法および装置
WO2006084376A1 (en) * 2005-02-09 2006-08-17 The University Of British Columbia Sub-microlitre electrostatic dispenser
US20060210443A1 (en) * 2005-03-14 2006-09-21 Stearns Richard G Avoidance of bouncing and splashing in droplet-based fluid transport
KR100624467B1 (ko) * 2005-05-13 2006-09-15 삼성전자주식회사 전기수력학적(ｅｌｅｃｔｒｏｈｙｄｒｏｄｙｎａｍｉｃ)현상을 이용하여 기판 상에 생체분자를 프린팅하는 장치
US20060266941A1 (en) * 2005-05-26 2006-11-30 Vestal Marvin L Method and apparatus for interfacing separations techniques to MALDI-TOF mass spectrometry
KR100668343B1 (ko) * 2005-08-12 2007-01-12 삼성전자주식회사 전기전하집중 현상을 이용하여 기판 상에 생체분자 액적을프린팅하는 장치 및 전기전하집중 현상을 이용하여인쇄용지 또는 인쇄기판 상에 잉크를 프린팅하는 장치
US8820265B2 (en) 2005-12-06 2014-09-02 Opertech Bio, Inc. High-throughput operant sensory discrimination apparatus and method
US7544933B2 (en) * 2006-01-17 2009-06-09 Purdue Research Foundation Method and system for desorption atmospheric pressure chemical ionization
KR101217550B1 (ko) * 2006-01-26 2013-01-02 삼성전자주식회사 방사형 전기삼투 유동을 이용한 증발하는 액적 내의 입자분포 제어 장치
KR100723427B1 (ko) * 2006-05-12 2007-05-30 삼성전자주식회사 기판상에 생체분자 액적을 프린팅하는 장치 및 방법
EP2136911A2 (de) 2007-01-19 2009-12-30 Biodot, Inc. Systeme und verfahren für hochgeschwindigkeitsarraydruck und -hybridisierung
US7838824B2 (en) * 2007-05-01 2010-11-23 Virgin Instruments Corporation TOF-TOF with high resolution precursor selection and multiplexed MS-MS
US7564026B2 (en) * 2007-05-01 2009-07-21 Virgin Instruments Corporation Linear TOF geometry for high sensitivity at high mass
US7564028B2 (en) * 2007-05-01 2009-07-21 Virgin Instruments Corporation Vacuum housing system for MALDI-TOF mass spectrometry
US7663100B2 (en) * 2007-05-01 2010-02-16 Virgin Instruments Corporation Reversed geometry MALDI TOF
US7589319B2 (en) 2007-05-01 2009-09-15 Virgin Instruments Corporation Reflector TOF with high resolution and mass accuracy for peptides and small molecules
US7667195B2 (en) * 2007-05-01 2010-02-23 Virgin Instruments Corporation High performance low cost MALDI MS-MS
US20090205581A1 (en) * 2008-02-15 2009-08-20 Redpoint Bio Corporation High-throughput operant sensory discrimination apparatus and method
EP2157599A1 (de) * 2008-08-21 2010-02-24 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO Verfahren und Vorrichtung zur Identifikation biologischer Materialien
JP5636614B2 (ja) * 2010-09-02 2014-12-10 学校法人立教学院 Ｌｃ−ｍａｌｄｉで得られたデータの比較解析方法
DK2665557T3 (da) 2011-01-21 2020-04-06 Biodot Inc Piezoelektrisk dispenser med en langsgående transducer og udskifteligt kapillærrør
US9702795B2 (en) * 2012-01-17 2017-07-11 The Scripps Research Institute Apparatus and method for producing specimens for electron microscopy
EP2805144A4 (de) * 2012-01-17 2015-09-09 Scripps Research Inst Herstellung von probenarrays auf einem elektronenmikroskopraster
CN104769410B (zh) 2012-11-06 2018-07-27 拜奥－多特公司 用于核型分析的细胞样本的受控印刷
AU2016246542B2 (en) 2015-04-06 2021-08-26 Nanocytomics, LLC Automated specimen deposition systems and associated methods
WO2017218882A1 (en) 2016-06-16 2017-12-21 Nanocytomics, LLC Automated staining system
KR102180624B1 (ko) * 2017-10-11 2020-11-18 주식회사 엘지화학 Maldi 질량분석법을 이용한 고분자의 정량분석방법 및 고분자 정량분석을 위한 maldi 질량분석용 시편의 제조방법
KR102121644B1 (ko) * 2017-11-23 2020-06-10 주식회사 엘지화학 Maldi 질량분석법을 이용한 고분자의 상대 정량분석방법
CN110075933B (zh) * 2018-01-25 2022-05-13 北京致雨生物科技有限公司 微液滴生成装置、系统及生成方法
KR102362175B1 (ko) * 2018-08-30 2022-02-11 주식회사 엘지화학 Maldi 질량 분석을 이용한 고분자의 상대적 정량분석방법
WO2020045821A1 (ko) * 2018-08-30 2020-03-05 주식회사 엘지화학 Maldi 질량 분석을 이용한 고분자의 상대적 정량분석방법
KR102362170B1 (ko) 2019-04-08 2022-02-11 주식회사 엘지화학 Maldi 질량분석을 이용한 고분자의 상대적 정량분석방법

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3476291A (en) * 1968-06-13 1969-11-04 Berkeley Scient Lab Inc Method and apparatus for dispensing measured quantities of liquids
US3661304A (en) * 1970-08-03 1972-05-09 Mead Corp Pressure impulse apparatus for initiating formation of fluid drops
US3941312A (en) * 1973-11-23 1976-03-02 Research and Development Laboratories of Ohno Company Limited Ink jet nozzle for use in a recording unit
FR2463920A1 (fr) * 1979-08-17 1981-02-27 Commissariat Energie Atomique Dispositif microdoseur de liquides
US4867947A (en) * 1986-09-08 1989-09-19 Sepragen Corporation Interface for liquid chromatograph-mass spectrometer
US5045172A (en) * 1987-11-25 1991-09-03 Princeton Biochemicals, Inc. Capillary electrophoresis apparatus
US5232565A (en) * 1988-09-27 1993-08-03 The Board Of Trustees Of The Leland Standford Junior University Capillary electrophoretic system
US5750015A (en) * 1990-02-28 1998-05-12 Soane Biosciences Method and device for moving molecules by the application of a plurality of electrical fields
DE69233087T2 (de) * 1991-11-22 2003-12-24 Affymetrix, Inc. (N.D.Ges.D.Staates Delaware) Verfahren zur Herstellung von Polymerarrays
DE4229005A1 (de) * 1992-08-31 1994-03-03 Linde Ag Dosierung flüssiger Substanzen
JPH07275690A (ja) * 1994-04-05 1995-10-24 Mitsubishi Electric Corp 浮遊装置
US5985356A (en) * 1994-10-18 1999-11-16 The Regents Of The University Of California Combinatorial synthesis of novel materials
SE9502251D0 (sv) * 1995-06-21 1995-06-21 Pharmacia Ab Flow-through sampling cell and use thereof
US5630925A (en) * 1995-07-13 1997-05-20 Beckman Instruments, Inc. Capillary electrophoresis using a conductive capillary tube
US5879949A (en) * 1995-11-22 1999-03-09 Board Of Supervisors Of Louisiana State University & Agricultural And Mechanical College Apparatus and method for rapid on-line electrochemistry and mass spectrometry
JP3361530B2 (ja) * 1996-06-28 2003-01-07 カリパー・テクノロジーズ・コープ． 電子ピペッタおよび電気泳動バイアスのための補償手段
US5916524A (en) * 1997-07-23 1999-06-29 Bio-Dot, Inc. Dispensing apparatus having improved dynamic range
US6284113B1 (en) * 1997-09-19 2001-09-04 Aclara Biosciences, Inc. Apparatus and method for transferring liquids
US6074725A (en) * 1997-12-10 2000-06-13 Caliper Technologies Corp. Fabrication of microfluidic circuits by printing techniques
DE19754978C2 (de) * 1997-12-11 2000-07-13 Bruker Daltonik Gmbh Probenträger für die MALDI-Massenspektrometrie nebst Verfahren zur Herstellung der Platten und zum Aufbringen der Proben
US5969350A (en) * 1998-03-17 1999-10-19 Comstock, Inc. Maldi/LDI time-of-flight mass spectrometer
US6191418B1 (en) * 1998-03-27 2001-02-20 Synsorb Biotech, Inc. Device for delivery of multiple liquid sample streams to a mass spectrometer
US6132685A (en) * 1998-08-10 2000-10-17 Caliper Technologies Corporation High throughput microfluidic systems and methods
US6162341A (en) * 1998-09-11 2000-12-19 The Perkin-Elmer Corporation Multi-channel capillary electrophoresis device including sheath-flow cuvette and replacable capillary array
US6132582A (en) * 1998-09-14 2000-10-17 The Perkin-Elmer Corporation Sample handling system for a multi-channel capillary electrophoresis device
US6103199A (en) * 1998-09-15 2000-08-15 Aclara Biosciences, Inc. Capillary electroflow apparatus and method
EP1876442A3 (de) * 1998-09-17 2008-03-05 Advion BioSciences, Inc. Integriertes monolithisches, auf Mikrobasis hergestelltes System und Verfahren zur Flüssigkeitschromatographie
US6149787A (en) * 1998-10-14 2000-11-21 Caliper Technologies Corp. External material accession systems and methods
US6149815A (en) * 1999-11-23 2000-11-21 Sauter; Andrew D. Precise electrokinetic delivery of minute volumes of liquid(s)
ATE340025T1 (de) * 2000-01-06 2006-10-15 Caliper Life Sciences Inc Vorrichtungen und verfahren für hochdurchsatz- probenentnahme und analyse
WO2001071311A2 (en) * 2000-03-17 2001-09-27 Nanostream, Inc. Electrostatic systems and methods for dispensing droplets
US6918309B2 (en) * 2001-01-17 2005-07-19 Irm Llc Sample deposition method and system
US6657191B2 (en) * 2001-03-02 2003-12-02 Bruker Daltonics Inc. Means and method for multiplexing sprays in an electrospray ionization source

Also Published As

Publication number Publication date
EP1358012A1 (de) 2003-11-05
CA2434305A1 (en) 2002-08-15
CA2434305C (en) 2010-03-09
EP1358012A4 (de) 2006-04-05
WO2002062475A1 (en) 2002-08-15
DE60228049D1 (de) 2008-09-18
US20020092366A1 (en) 2002-07-18
AU2007221973A1 (en) 2007-11-01
JP4162207B2 (ja) 2008-10-08
WO2002062475B1 (en) 2002-11-21
US20050232823A1 (en) 2005-10-20
AU2007221973B2 (en) 2009-12-10
JP2004529325A (ja) 2004-09-24
US6918309B2 (en) 2005-07-19
US7578206B2 (en) 2009-08-25
EP1358012B1 (de) 2008-08-06

Similar Documents

Publication Publication Date Title
DE60228049D1 (de) Probenablageverfahren und -system
US7516714B2 (en) Immobilizing device
Otsuka et al. Scanning probe electrospray ionization for ambient mass spectrometry
Jin et al. Swan probe: A nanoliter-scale and high-throughput sampling interface for coupling electrospray ionization mass spectrometry with microfluidic droplet array and multiwell plate
WO2008098236A3 (en) Droplet actuator devices and methods employing magnetic beads
EP1036336A1 (de) Vorrichtung zur elektrisch ausgelösten mikrotropfenabgabe mit einem dispensierkopf
KR960025997A (ko) 전자 방출 소자, 전자 소스 기판, 전자 소스, 디스플레이 패널 및 화상 형성 장치, 및 그 제조방법
WO2001079849A3 (en) Protein expression system arrays and use in biological screening
GB2429976A (en) Repeatable protein arrays
WO2005094389A3 (en) Method and system for desorption electrospray ionization
WO2001073119A3 (en) Methods for genotyping by hybridization analysis
WO2007075488A3 (en) System and method for scientific information knowledge management
Barreiro-Lage et al. “Smart Decomposition” of cyclic Alanine-Alanine dipeptide by VUV radiation: A seed for the synthesis of biologically relevant species
CA2411532A1 (en) Atmospheric pressure photoionizer for mass spectrometry
Krenkel et al. Ultrahigh-throughput sample analysis using liquid atmospheric pressure matrix-assisted laser desorption/ionization mass spectrometry
EA200500911A1 (ru) Планшеты и системы для крупномасштабной электропорации и способы их применения
AU2003233194A1 (en) Continuous method for obtaining butenes from a c4 fraction
ATE354863T1 (de) Magnetronsputtereinrichtung, zylinderkathode und verfahren zur aufbringung von dünnen mehrkomponentenschichten auf einem substrat
US9396916B2 (en) Electrokinetically controlled calibrant delivery
EP0966021A3 (de) Vorrichtung zum Beschichten von Substraten in einer Vakuumkammer
FR2857451B1 (fr) Procede et dispositif pour l'analyse de milieux reactionnels vivants
US20060110833A1 (en) Method and apparatus for coupling an analyte supply to an electrodynamic droplet processor
GB0223666D0 (en) Arrays of molecules and their production
DE60111632D1 (de) Elektrostatisch erregtes beschichtungsverfahren und vorrichtung mit fokussiertem elektrodenfeld
EP2049260B1 (de) Kanalfreies transportmedium für fluidprobe

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties