ATE403755T1 - Identifizierung einer erbb2- genexpressionssignatur bei brustkrebs - Google Patents
Identifizierung einer erbb2- genexpressionssignatur bei brustkrebsInfo
- Publication number
- ATE403755T1 ATE403755T1 AT04769358T AT04769358T ATE403755T1 AT E403755 T1 ATE403755 T1 AT E403755T1 AT 04769358 T AT04769358 T AT 04769358T AT 04769358 T AT04769358 T AT 04769358T AT E403755 T1 ATE403755 T1 AT E403755T1
- Authority
- AT
- Austria
- Prior art keywords
- gene expression
- identification
- breast cancer
- expression signature
- erbb2 gene
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49849703P | 2003-08-28 | 2003-08-28 | |
| US10/928,465 US20050089899A1 (en) | 2003-08-28 | 2004-08-27 | Identification of an ERBB2 gene expression signature in breast cancers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE403755T1 true ATE403755T1 (de) | 2008-08-15 |
Family
ID=34278600
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04769358T ATE403755T1 (de) | 2003-08-28 | 2004-08-27 | Identifizierung einer erbb2- genexpressionssignatur bei brustkrebs |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20050089899A1 (de) |
| EP (2) | EP1668152B1 (de) |
| AT (1) | ATE403755T1 (de) |
| DE (1) | DE602004015626D1 (de) |
| ES (1) | ES2311852T3 (de) |
| PL (1) | PL1668152T3 (de) |
| WO (1) | WO2005021788A1 (de) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050260659A1 (en) * | 2004-04-23 | 2005-11-24 | Exagen Diagnostics, Inc. | Compositions and methods for breast cancer prognosis |
| CA2611198C (en) | 2005-06-10 | 2015-04-28 | Saint Louis University | Methods for the selection of aptamers |
| US20090203533A1 (en) * | 2005-07-08 | 2009-08-13 | Siemens Medicals Solutions Diagnositcs Gmbh | Methods and Kits for Predicting and Monitoring Direct Response to Cancer Therapy |
| CN103217520A (zh) * | 2006-02-27 | 2013-07-24 | 靶向分子诊断有限责任公司 | 用于减少细胞脂肪和预测用酪氨酸激酶抑制剂治疗后的心脏毒性的组合物和方法 |
| US20100113299A1 (en) * | 2008-10-14 | 2010-05-06 | Von Hoff Daniel D | Gene and gene expressed protein targets depicting biomarker patterns and signature sets by tumor type |
| US8768629B2 (en) | 2009-02-11 | 2014-07-01 | Caris Mpi, Inc. | Molecular profiling of tumors |
| US12366585B2 (en) | 2006-05-18 | 2025-07-22 | Caris Mpi, Inc. | Molecular profiling of tumors |
| JP2009537154A (ja) | 2006-05-18 | 2009-10-29 | モレキュラー プロファイリング インスティテュート， インコーポレイテッド | 疾患状態に対する個別化された医学的介入を決定するためのシステムおよび方法 |
| EP2390363A1 (de) * | 2006-06-02 | 2011-11-30 | GlaxoSmithKline Biologicals s.a. | Verfahren zur Indentifizierung des Ansprechens bzw. Nichtansprechens eines Patienten auf eine Immuntherapie basierend auf die Differentielle Expression vom Gen PRF1 |
| JP2010537658A (ja) * | 2007-09-07 | 2010-12-09 | ユニヴェルシテ リブル ドゥ ブリュッセル | Ｈｅｒ２＋患者におけるガンの予後判定のための方法およびツール |
| WO2009103790A2 (en) | 2008-02-21 | 2009-08-27 | Universite Libre De Bruxelles | Method and kit for the detection of genes associated with pik3ca mutation and involved in pi3k/akt pathway activation in the er-positive and her2-positive subtypes with clinical implications |
| US20110130296A1 (en) * | 2008-03-14 | 2011-06-02 | The Regents Of The University Of California | Multi-gene classifiers and prognostic indicators for cancers |
| US20100267803A1 (en) * | 2008-11-07 | 2010-10-21 | The Research Foundation Of State University Of New York | Regulators Of Fat Metabolism As Anti-Cancer Targets |
| CA2743211A1 (en) | 2008-11-12 | 2010-05-20 | Caris Life Sciences Luxembourg Holdings, S.A.R.L. | Methods and systems of using exosomes for determining phenotypes |
| JP2012511323A (ja) * | 2008-12-10 | 2012-05-24 | イプソゲン | 腫瘍中のｅｒｂｂ２の変化を特定するための方法 |
| EP2253715A1 (de) * | 2009-05-14 | 2010-11-24 | RWTH Aachen | Neue Targets zur Krebstherapie und/oder -diagnose |
| GB0917457D0 (en) * | 2009-10-06 | 2009-11-18 | Glaxosmithkline Biolog Sa | Method |
| CA2787483C (en) | 2010-02-12 | 2018-03-06 | Saint Louis University | Molecular biosensors capable of signal amplification |
| EP2542696B1 (de) | 2010-03-01 | 2016-09-28 | Caris Life Sciences Switzerland Holdings GmbH | Theranostik-biomarker |
| BR112012025593A2 (pt) | 2010-04-06 | 2019-06-25 | Caris Life Sciences Luxembourg Holdings | biomarcadores em circulação para doença |
| JP2014519813A (ja) | 2011-04-25 | 2014-08-21 | オーエスアイ・ファーマシューティカルズ，エルエルシー | 癌薬剤発見、診断、および治療におけるｅｍｔ遺伝子シグネチャーの使用 |
| WO2016025785A1 (en) * | 2014-08-15 | 2016-02-18 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Systems and methods for characterizing cancer |
| EP3191843A1 (de) | 2014-09-12 | 2017-07-19 | Mediomics, LLC | Molekulare biosensoren mit einem modularen design |
| JP6793451B2 (ja) * | 2014-11-14 | 2020-12-02 | キヤノンメディカルシステムズ株式会社 | 被検細胞の細胞特性を評価するための遺伝子マーカー、方法、レポーターベクター、プライマーセットおよびアッセイキット、並びに細胞特性評価装置 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002010436A2 (en) * | 2000-07-28 | 2002-02-07 | The Brigham And Women's Hospital, Inc. | Prognostic classification of breast cancer |
| US20030096237A1 (en) * | 2000-08-28 | 2003-05-22 | Ulrich Certa | Determination of the ability of patients to respond to a tumor treatment |
| AU2002255478A1 (en) * | 2001-01-10 | 2002-09-12 | Pe Corporation (Ny) | Kits, such as nucleic acid arrays, comprising a majority of human exons or transcripts, for detecting expression and other uses thereof |
| US20070015148A1 (en) * | 2001-01-25 | 2007-01-18 | Orr Michael S | Gene expression profiles in breast tissue |
| AU2002316251A1 (en) * | 2001-06-18 | 2003-01-02 | Rosetta Inpharmatics, Inc. | Diagnosis and prognosis of breast cancer patients |
| US20030099974A1 (en) * | 2001-07-18 | 2003-05-29 | Millennium Pharmaceuticals, Inc. | Novel genes, compositions, kits and methods for identification, assessment, prevention, and therapy of breast cancer |
| US20030198972A1 (en) * | 2001-12-21 | 2003-10-23 | Erlander Mark G. | Grading of breast cancer |
| US20030190689A1 (en) * | 2002-04-05 | 2003-10-09 | Cell Signaling Technology,Inc. | Molecular profiling of disease and therapeutic response using phospho-specific antibodies |
-
2004
- 2004-08-27 EP EP04769358A patent/EP1668152B1/de not_active Expired - Lifetime
- 2004-08-27 PL PL04769358T patent/PL1668152T3/pl unknown
- 2004-08-27 WO PCT/IB2004/002968 patent/WO2005021788A1/en not_active Ceased
- 2004-08-27 US US10/928,465 patent/US20050089899A1/en not_active Abandoned
- 2004-08-27 DE DE602004015626T patent/DE602004015626D1/de not_active Expired - Lifetime
- 2004-08-27 EP EP08007447A patent/EP1980629A3/de not_active Withdrawn
- 2004-08-27 ES ES04769358T patent/ES2311852T3/es not_active Expired - Lifetime
- 2004-08-27 AT AT04769358T patent/ATE403755T1/de not_active IP Right Cessation
-
2008
- 2008-09-17 US US12/212,282 patent/US20090092983A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ES2311852T3 (es) | 2009-02-16 |
| DE602004015626D1 (de) | 2008-09-18 |
| EP1668152A1 (de) | 2006-06-14 |
| EP1980629A3 (de) | 2008-12-17 |
| EP1668152B1 (de) | 2008-08-06 |
| US20090092983A1 (en) | 2009-04-09 |
| US20050089899A1 (en) | 2005-04-28 |
| WO2005021788A1 (en) | 2005-03-10 |
| EP1980629A2 (de) | 2008-10-15 |
| PL1668152T3 (pl) | 2009-06-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE403755T1 (de) | Identifizierung einer erbb2- genexpressionssignatur bei brustkrebs | |
| CY1112631T1 (el) | ΜΕΘΟΔΟΙ ΤΑΥΤΟΠΟΙΗΣΗΣ ΟΓΚΩΝ ΠΟΥ ΑΠΟΚΡΙΝΟΝΤΑΙ ΣΕ ΑΓΩΓΗ ΜΕ ΑΝΤΙΣΩΜΑΤΑ ΑΝΤΙ-ΕrbB2 | |
| AU2014204426B2 (en) | Integrated nucleic acid analysis | |
| ATE410524T1 (de) | Verfahren und nukleinsäuren für die analyse von zellulären proliferationsstörungen | |
| ATE507310T1 (de) | Verfahren für den nachweis von leberkrebs, leberkrebsrisiko, risiko eines leberkrebsrezidivs,bösartigem leberkrebs und progression von leberkrebs mit der zeit anhand von methyliertem cytosin im basp1-gen | |
| WO2008154098A3 (en) | Reagents and methods for mirna expression analysis and identification of cancer biomarkers | |
| EP4574992A3 (de) | Kombinatorisches dna-screening | |
| ATE496142T1 (de) | Verfahren zur diagnose von nicht-kleinzelligem lungenkrebs | |
| EP4279612A3 (de) | Analyse von fragmentierungsmustern von zellfreier dna | |
| ATE534748T1 (de) | Direkter snp-nachweis mit nichtamplifizierter dna | |
| ATE403743T1 (de) | Genetische veränderungen, die mit lungencarzinomen korrelieren | |
| EP2237019A3 (de) | Blutanalysegerät und Verfahren zur Bestimmung des Vorliegens und Nichtvorliegens von Lymphoblasten in einer Blutprobe | |
| DE602004021185D1 (de) | Auf bio-barcodes beruhender nachweis von zielanalyten | |
| WO2004110246A3 (en) | Methods and compositions for diagnosing conditions associated with specific dna methylation patterns | |
| DE60326748D1 (de) | Verfahren zur identifizierung des brustkrebsrisikos | |
| WO2007050777A3 (en) | Methods and compositions for diagnosing lung cancer with specific dna methylation patterns | |
| WO2009151757A3 (en) | Method and apparatus for forensic screening | |
| WO2008104985A3 (en) | Methods for distingushing between lung squamous carcinoma and other non smallcell lung cancers | |
| WO2004005530A3 (en) | Compositions and methods for treatment and detection of multiple cancers | |
| WO2008104984A3 (en) | Diagnosis and prognosis of various types of cancers | |
| WO2009132928A3 (en) | Molecular markers for cancer prognosis | |
| ATE494390T1 (de) | Verfahren und nukleinsäuren zur analyse von störungen der proliferation von kolonzellen | |
| CY1115258T1 (el) | Μεθοδοι και χρησεις που περιλαμβανουν τις γενετικες παρεκκλισεις του ναv3 και την παρεκκλινουσα εκφραση πολλαπλων γονιδιων | |
| NZ584656A (en) | Mitochondrial dna deletion between about residues 12317-16254 for use in the detection of cancer | |
| WO2010070637A3 (en) | Method for distinguishing between adrenal tumors |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |