ATE403873T1 - Verfahren zur überwachung der typ-ii- kollagenabbau in knorpeln - Google Patents

Verfahren zur überwachung der typ-ii- kollagenabbau in knorpeln

Info

Publication number
ATE403873T1
ATE403873T1 AT03718685T AT03718685T ATE403873T1 AT E403873 T1 ATE403873 T1 AT E403873T1 AT 03718685 T AT03718685 T AT 03718685T AT 03718685 T AT03718685 T AT 03718685T AT E403873 T1 ATE403873 T1 AT E403873T1
Authority
AT
Austria
Prior art keywords
cartilage
collagen type
collagen degradation
monitoring type
monitoring
Prior art date
Application number
AT03718685T
Other languages
English (en)
Inventor
Jean-Yves Reginster
Michelle Deberg
Yves Henrotin
Stephan Christgau
Original Assignee
Univ Liege
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Liege filed Critical Univ Liege
Application granted granted Critical
Publication of ATE403873T1 publication Critical patent/ATE403873T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/84—Bones; tendons; teeth; cartilage

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Tires In General (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
AT03718685T 2002-03-13 2003-03-12 Verfahren zur überwachung der typ-ii- kollagenabbau in knorpeln ATE403873T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36392602P 2002-03-13 2002-03-13
DKPA200200380 2002-03-13

Publications (1)

Publication Number Publication Date
ATE403873T1 true ATE403873T1 (de) 2008-08-15

Family

ID=27806429

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03718685T ATE403873T1 (de) 2002-03-13 2003-03-12 Verfahren zur überwachung der typ-ii- kollagenabbau in knorpeln

Country Status (7)

Country Link
US (2) US7410770B2 (de)
EP (1) EP1485718B1 (de)
AT (1) ATE403873T1 (de)
AU (1) AU2003222759A1 (de)
DE (1) DE60322682D1 (de)
ES (1) ES2311696T3 (de)
WO (1) WO2003076947A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010003016A2 (en) * 2008-07-04 2010-01-07 Axial Biotech, Inc Genetic markers associated with degenerative disc disease and uses thereof
KR101705353B1 (ko) * 2013-10-17 2017-02-13 경북대학교 산학협력단 ApoPep-1 펩타이드 프로브를 포함하는 골관절염 조기진단용 시약
EP3233909A1 (de) * 2014-12-19 2017-10-25 Université de Liège Coll2-1-peptid und dessen nitrierte form als therapeutische targets zur behandlung von osteoarthritis

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5702909A (en) * 1987-11-06 1997-12-30 Washington Research Foundation Methods of detecting collagen type II degradation in vivo
US4973666A (en) * 1987-11-06 1990-11-27 Washington Research Foundation Peptide fragments containing HP and LP cross-links
US6132976A (en) * 1992-12-04 2000-10-17 Shriners Hospitals For Children Immunoassays for the measurement of collagen denaturation and cleavage in cartilage
US6110689A (en) * 1994-01-21 2000-08-29 Osteometer A/S Method of assaying collagen fragments in body fluids, a test kit and means for carrying out the method and use of the method to diagnose the presence of disorders associated with the metabolism of collagen
GB9928052D0 (en) 1999-11-26 2000-01-26 Osteometer Biotech As Assay of isomerised and/or optically inverted proteins and protein fragments
WO2003006603A2 (en) * 2001-07-12 2003-01-23 Arexis Ab Triple polypeptide complexes

Also Published As

Publication number Publication date
AU2003222759A8 (en) 2003-09-22
EP1485718B1 (de) 2008-08-06
EP1485718A2 (de) 2004-12-15
DE60322682D1 (de) 2008-09-18
AU2003222759A1 (en) 2003-09-22
ES2311696T3 (es) 2009-02-16
WO2003076947A3 (en) 2004-04-08
US20090042220A1 (en) 2009-02-12
US7728112B2 (en) 2010-06-01
WO2003076947A2 (en) 2003-09-18
US7410770B2 (en) 2008-08-12
US20050170429A1 (en) 2005-08-04

Similar Documents

Publication Publication Date Title
PT638172E (pt) Metodos e composicoes para monitorizacao do processamento celular da proteina precursora beta-amiloide
EA200100485A1 (ru) Соединение сдлс и способ его измерения
EP1571970A4 (de) Diagnose und überwachung von krankheiten
NO20043419L (no) Nytt cytokin, zcytor17-ligand
UA89616C2 (ru) Гидролизат казеина, способ его получения и применения
CY1112330T1 (el) Πρωτεϊνες συνδεσης gag
WO2003063760A3 (en) Peptides antibodies directed thereagainst and methods using same for diagnosing and treating amyloid-associated diseases
DE69937835D1 (de) Antikörper für apoptosemarker und anwendungsverfahren
ATE335763T1 (de) Sandwich-immunoassay zur bestimmung von proanp- teilpeptiden
ATE292801T1 (de) Verfahren zum screening von inhibitoren von asp2
DE69729954D1 (de) Identifizierungsverfahren für Substanzen die an das Pyk2 Polypeptid binden
ATE502305T1 (de) Verwendung von vorstufen von enkephalinen und/oder deren fragmenten in der medizinischen diagnostik
MX2013013931A (es) Medios y metodos para diagnosticar y tratar esclerosis multiple.
WO2004020668A3 (en) Method for treating synovial sarcoma
EP1132402A4 (de) Peptidfragmente mit den zelltod verhindernden aktivität
AU2008221661B2 (en) Diagnosis of collagen IX destruction
ATE403873T1 (de) Verfahren zur überwachung der typ-ii- kollagenabbau in knorpeln
WO2003027149A1 (fr) Anticorps et utilisation de ce dernier
BRPI0306644B8 (pt) método para produzir um peptídeo modificado
ATE517629T1 (de) Verwendung eines proteins der crmp familie zur behandlung von krankheiten des immunsystems
DK0769025T3 (da) Metoder og sammensætninger i relation til proteoglycanproteiner til diagnosticering af brusknedbrydning
ATE499614T1 (de) Verfahren zur bestimmung eines gewebeabbauverfahrens durch nachweis von comp- neoepitopen
DK1960515T3 (da) Inflammationshæmmende peptider
DE69734779D1 (de) Erhöhte ausbeuten eines kristallinen proteins durch verwendung eines festen adsorptionsmaterials
DE60308176D1 (de) Vorrichtung von peptid- oder proteindarstellung, verfahren zu deren herstellung und deren verwendung

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties