ATE405292T1 - Injektierbare wässrige paclitaxel-lösungen und verfahren zu ihrer herstellung - Google Patents

Injektierbare wässrige paclitaxel-lösungen und verfahren zu ihrer herstellung

Info

Publication number: ATE405292T1
Authority: AT; Austria
Prior art keywords: pharmaceutical composition; production; injectable aqueous; injectable pharmaceutical; paclitaxel
Prior art date: 2004-11-24

Application number

AT05003915T

Other languages

English (en)

Inventor

Fang-Yu Lee

Shan-Chiung Chen

Bin-Ken Chen

Chiung-Ju Tsai

Yuan-Ken Lin

Original Assignee

Yung Shin Pharm Ind Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-11-24

Filing date

2005-02-23

Publication date

2008-09-15

2005-02-23 Application filed by Yung Shin Pharm Ind Co Ltd filed Critical Yung Shin Pharm Ind Co Ltd

2008-09-15 Application granted granted Critical

2008-09-15 Publication of ATE405292T1 publication Critical patent/ATE405292T1/de

Links

229930012538 Paclitaxel Natural products 0.000 title abstract 4
229960001592 paclitaxel Drugs 0.000 title abstract 4
RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 title abstract 4
239000008194 pharmaceutical composition Substances 0.000 abstract 4
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
239000002246 antineoplastic agent Substances 0.000 abstract 1
239000007864 aqueous solution Substances 0.000 abstract 1
239000004359 castor oil Substances 0.000 abstract 1
235000019438 castor oil Nutrition 0.000 abstract 1
ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Oil, Petroleum & Natural Gas (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Dermatology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

AT05003915T 2004-11-24 2005-02-23 Injektierbare wässrige paclitaxel-lösungen und verfahren zu ihrer herstellung ATE405292T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US10/995,262 US7361683B2 (en)	2004-11-24	2004-11-24	Paclitaxel aqueous injection solution and methods for preparing the same

Publications (1)

Publication Number	Publication Date
ATE405292T1 true ATE405292T1 (de)	2008-09-15

Family

ID=34933891

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT05003915T ATE405292T1 (de)	2004-11-24	2005-02-23	Injektierbare wässrige paclitaxel-lösungen und verfahren zu ihrer herstellung

Country Status (6)

Country	Link
US (1)	US7361683B2 (de)
EP (1)	EP1666069B1 (de)
JP (1)	JP4805599B2 (de)
AT (1)	ATE405292T1 (de)
DE (1)	DE602005009110D1 (de)
TW (1)	TWI303566B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PL2047857T3 (pl) *	2006-06-29	2012-05-31	Kyoto Biopharma Inc	Środek przeznaczony do wstrzykiwania zawierający antybiotyk i roztwór do wstrzykiwania zawierający środek
GB2445746A (en) *	2007-01-17	2008-07-23	Texcontor Ets	Use of carbonated water as a solvent for freeze drying, and method of purification comprising dissolution of material in carbonated water and freeze drying
DE102007021862A1 (de) *	2007-05-10	2008-11-13	Merck Patent Gmbh	Wässrige pharmazeutische Zubereitung
CN101396354B (zh) *	2007-09-30	2010-12-01	江苏恒瑞医药股份有限公司	一种稳定的塔三烷类化合物液体组合物及其制备方法和其应用
EP2829273B1 (de) *	2012-03-22	2018-08-29	Ensuiko Sugar Refining Co., Ltd.	Verfahren zur herstellung von liposomen zur verkapselung von paclitaxel-monoglycosid und/oder docetaxel-monoglycosid
EP2884963B1 (de) *	2012-08-15	2017-12-27	Yung Shin Pharm. Ind. Co. Ltd.	Stabile pharmazeutische formulierung von cabazitaxel
TW201420130A (zh) *	2012-09-26	2014-06-01	Neochemir Inc	溶解有二氧化碳之液狀藥劑及其投藥方法
WO2015106094A1 (en) *	2014-01-10	2015-07-16	Atossa Genetics Inc.	Transpapillary methods and compositions for diagnosing and treating breast conditions
ES3055492T3 (en)	2015-09-16	2026-02-12	Dfb Soria Llc	Delivery of drug nanoparticles and methods of use thereof
WO2018170196A1 (en)	2017-03-15	2018-09-20	Dfb Soria, Llc	Topical therapy for the treatment of skin malignancies using nanoparticles of taxanes
EP3765035A4 (de)	2018-03-16	2021-10-27	DFB Soria, LLC	Topische therapie zur behandlung von zervikalen intraepithelialen neoplasien (cin) und gebärmutterhalskrebs unter verwendung von taxannanopartikeln

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU5612694A (en)	1992-11-27	1994-06-22	Napro Biotherapeutics, Inc.	Injectable composition
TW406020B (en)	1993-09-29	2000-09-21	Bristol Myers Squibb Co	Stabilized pharmaceutical composition and its method for preparation and stabilizing solvent
JP4000426B2 (ja) *	1996-05-08	2007-10-31	株式会社大塚製薬工場	輸液製剤
JP3375518B2 (ja) *	1997-06-23	2003-02-10	清水製薬株式会社	注射剤
JP2003201242A (ja) *	2001-12-28	2003-07-18	Shimizu Pharmaceutical Co Ltd	重曹リンゲル様液剤

2004
- 2004-11-24 US US10/995,262 patent/US7361683B2/en not_active Expired - Fee Related
2005
- 2005-02-23 DE DE602005009110T patent/DE602005009110D1/de not_active Expired - Lifetime
- 2005-02-23 EP EP05003915A patent/EP1666069B1/de not_active Expired - Lifetime
- 2005-02-23 AT AT05003915T patent/ATE405292T1/de not_active IP Right Cessation
- 2005-04-15 JP JP2005118226A patent/JP4805599B2/ja not_active Expired - Fee Related
- 2005-06-02 TW TW094118128A patent/TWI303566B/zh not_active IP Right Cessation

Also Published As

Publication number	Publication date
JP4805599B2 (ja)	2011-11-02
US20060111432A1 (en)	2006-05-25
EP1666069B1 (de)	2008-08-20
JP2006143699A (ja)	2006-06-08
DE602005009110D1 (de)	2008-10-02
EP1666069A1 (de)	2006-06-07
TWI303566B (en)	2008-12-01
TW200616616A (en)	2006-06-01
US7361683B2 (en)	2008-04-22

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Legal Events

Date	Code	Title	Description
2009-02-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties