ATE405292T1 - Injektierbare wässrige paclitaxel-lösungen und verfahren zu ihrer herstellung - Google Patents
Injektierbare wässrige paclitaxel-lösungen und verfahren zu ihrer herstellungInfo
- Publication number
- ATE405292T1 ATE405292T1 AT05003915T AT05003915T ATE405292T1 AT E405292 T1 ATE405292 T1 AT E405292T1 AT 05003915 T AT05003915 T AT 05003915T AT 05003915 T AT05003915 T AT 05003915T AT E405292 T1 ATE405292 T1 AT E405292T1
- Authority
- AT
- Austria
- Prior art keywords
- pharmaceutical composition
- production
- injectable aqueous
- injectable pharmaceutical
- paclitaxel
- Prior art date
Links
- 229930012538 Paclitaxel Natural products 0.000 title abstract 4
- 229960001592 paclitaxel Drugs 0.000 title abstract 4
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 title abstract 4
- 239000008194 pharmaceutical composition Substances 0.000 abstract 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000004359 castor oil Substances 0.000 abstract 1
- 235000019438 castor oil Nutrition 0.000 abstract 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/995,262 US7361683B2 (en) | 2004-11-24 | 2004-11-24 | Paclitaxel aqueous injection solution and methods for preparing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE405292T1 true ATE405292T1 (de) | 2008-09-15 |
Family
ID=34933891
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05003915T ATE405292T1 (de) | 2004-11-24 | 2005-02-23 | Injektierbare wässrige paclitaxel-lösungen und verfahren zu ihrer herstellung |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7361683B2 (de) |
| EP (1) | EP1666069B1 (de) |
| JP (1) | JP4805599B2 (de) |
| AT (1) | ATE405292T1 (de) |
| DE (1) | DE602005009110D1 (de) |
| TW (1) | TWI303566B (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2378279T3 (es) * | 2006-06-29 | 2012-04-10 | Arigen Pharmaceuticals, Inc. | Agente destinado a ser utilizado para una inyección que comprende antibiótico, y solución para inyección que comprende el agente |
| GB2445746A (en) * | 2007-01-17 | 2008-07-23 | Texcontor Ets | Use of carbonated water as a solvent for freeze drying, and method of purification comprising dissolution of material in carbonated water and freeze drying |
| DE102007021862A1 (de) * | 2007-05-10 | 2008-11-13 | Merck Patent Gmbh | Wässrige pharmazeutische Zubereitung |
| CN101396354B (zh) * | 2007-09-30 | 2010-12-01 | 江苏恒瑞医药股份有限公司 | 一种稳定的塔三烷类化合物液体组合物及其制备方法和其应用 |
| CN104203251B (zh) * | 2012-03-22 | 2017-05-31 | 盐水港精糖株式会社 | 内包紫杉醇单糖苷和/或紫杉萜单糖苷的脂质体的制造方法 |
| EP2884963B1 (de) * | 2012-08-15 | 2017-12-27 | Yung Shin Pharm. Ind. Co. Ltd. | Stabile pharmazeutische formulierung von cabazitaxel |
| TW201420130A (zh) * | 2012-09-26 | 2014-06-01 | Neochemir Inc | 溶解有二氧化碳之液狀藥劑及其投藥方法 |
| WO2015106094A1 (en) * | 2014-01-10 | 2015-07-16 | Atossa Genetics Inc. | Transpapillary methods and compositions for diagnosing and treating breast conditions |
| KR102742522B1 (ko) | 2015-09-16 | 2024-12-12 | 디에프비 소리아, 엘엘씨 | 약물 나노입자 전달체 및 이의 제조방법 |
| JP2020514359A (ja) | 2017-03-15 | 2020-05-21 | ディーエフビー ソリア リミテッド ライアビリティ カンパニー | タキサンのナノ粒子を用いる皮膚悪性腫瘍処置のための局所療法 |
| EP3765035A4 (de) | 2018-03-16 | 2021-10-27 | DFB Soria, LLC | Topische therapie zur behandlung von zervikalen intraepithelialen neoplasien (cin) und gebärmutterhalskrebs unter verwendung von taxannanopartikeln |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2149150C (en) * | 1992-11-27 | 2000-08-01 | David R. Carver | Injectable taxol composition with improved stability |
| TW406020B (en) * | 1993-09-29 | 2000-09-21 | Bristol Myers Squibb Co | Stabilized pharmaceutical composition and its method for preparation and stabilizing solvent |
| JP4000426B2 (ja) * | 1996-05-08 | 2007-10-31 | 株式会社大塚製薬工場 | 輸液製剤 |
| JP3375518B2 (ja) * | 1997-06-23 | 2003-02-10 | 清水製薬株式会社 | 注射剤 |
| JP2003201242A (ja) * | 2001-12-28 | 2003-07-18 | Shimizu Pharmaceutical Co Ltd | 重曹リンゲル様液剤 |
-
2004
- 2004-11-24 US US10/995,262 patent/US7361683B2/en not_active Expired - Fee Related
-
2005
- 2005-02-23 EP EP05003915A patent/EP1666069B1/de not_active Expired - Lifetime
- 2005-02-23 AT AT05003915T patent/ATE405292T1/de not_active IP Right Cessation
- 2005-02-23 DE DE602005009110T patent/DE602005009110D1/de not_active Expired - Lifetime
- 2005-04-15 JP JP2005118226A patent/JP4805599B2/ja not_active Expired - Fee Related
- 2005-06-02 TW TW094118128A patent/TWI303566B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1666069A1 (de) | 2006-06-07 |
| EP1666069B1 (de) | 2008-08-20 |
| US20060111432A1 (en) | 2006-05-25 |
| JP4805599B2 (ja) | 2011-11-02 |
| TW200616616A (en) | 2006-06-01 |
| DE602005009110D1 (de) | 2008-10-02 |
| TWI303566B (en) | 2008-12-01 |
| US7361683B2 (en) | 2008-04-22 |
| JP2006143699A (ja) | 2006-06-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |