ATE405589T1 - Für den snorf25-rezeptor kodierende dna - Google Patents
Für den snorf25-rezeptor kodierende dnaInfo
- Publication number
- ATE405589T1 ATE405589T1 AT00908748T AT00908748T ATE405589T1 AT E405589 T1 ATE405589 T1 AT E405589T1 AT 00908748 T AT00908748 T AT 00908748T AT 00908748 T AT00908748 T AT 00908748T AT E405589 T1 ATE405589 T1 AT E405589T1
- Authority
- AT
- Austria
- Prior art keywords
- mammalian snorf25
- snorf25 receptors
- receptors
- nucleic acid
- methods
- Prior art date
Links
- 238000000034 method Methods 0.000 abstract 4
- 108020004707 nucleic acids Proteins 0.000 abstract 4
- 150000007523 nucleic acids Chemical class 0.000 abstract 4
- 102000039446 nucleic acids Human genes 0.000 abstract 4
- 239000000556 agonist Substances 0.000 abstract 2
- 239000005557 antagonist Substances 0.000 abstract 2
- 239000013598 vector Substances 0.000 abstract 2
- 108020000948 Antisense Oligonucleotides Proteins 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 108020004711 Nucleic Acid Probes Proteins 0.000 abstract 1
- 230000005856 abnormality Effects 0.000 abstract 1
- 239000000074 antisense oligonucleotide Substances 0.000 abstract 1
- 238000012230 antisense oligonucleotides Methods 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000002853 nucleic acid probe Substances 0.000 abstract 1
- 230000009261 transgenic effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Biophysics (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25537699A | 1999-02-22 | 1999-02-22 | |
| US09/387,699 US6221660B1 (en) | 1999-02-22 | 1999-08-13 | DNA encoding SNORF25 receptor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE405589T1 true ATE405589T1 (de) | 2008-09-15 |
Family
ID=26944658
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00908748T ATE405589T1 (de) | 1999-02-22 | 2000-02-22 | Für den snorf25-rezeptor kodierende dna |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US6221660B1 (de) |
| EP (1) | EP1075493B1 (de) |
| JP (2) | JP2002539772A (de) |
| AT (1) | ATE405589T1 (de) |
| AU (1) | AU777247B2 (de) |
| CA (1) | CA2362906A1 (de) |
| CY (1) | CY1108503T1 (de) |
| DE (1) | DE60039948D1 (de) |
| DK (1) | DK1075493T3 (de) |
| ES (1) | ES2312333T3 (de) |
| PT (1) | PT1075493E (de) |
| WO (1) | WO2000050562A2 (de) |
Families Citing this family (68)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE42190E1 (en) | 1998-11-20 | 2011-03-01 | Arena Pharmaceuticals, Inc. | Method of identifying a compound for inhibiting or stimulating human G protein-coupled receptors |
| US7816492B2 (en) * | 1998-11-20 | 2010-10-19 | Arena Pharmaceuticals, Inc. | Human G protein-coupled receptors |
| DK1133559T3 (da) * | 1998-11-20 | 2006-04-10 | Arena Pharm Inc | Human-G-protein-koblet orphan receptor RUP3 |
| US20030017528A1 (en) * | 1998-11-20 | 2003-01-23 | Ruoping Chen | Human orphan G protein-coupled receptors |
| US6221660B1 (en) * | 1999-02-22 | 2001-04-24 | Synaptic Pharmaceutical Corporation | DNA encoding SNORF25 receptor |
| US20030125539A1 (en) * | 1999-02-22 | 2003-07-03 | Synaptic Pharmaceutical Corporation | DNA encoding SNORF25 receptor |
| CA2375047A1 (en) | 1999-05-28 | 2000-12-07 | Synaptic Pharmaceutical Corporation | Dna encoding snorf33 receptor |
| GB9923177D0 (en) * | 1999-09-30 | 1999-12-01 | Pfizer Ltd | Novel polypeptide |
| JP2003513629A (ja) * | 1999-11-03 | 2003-04-15 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング | 新規なgpcr_kd5ポリペプチドおよびそのdna配列 |
| CA2388865A1 (en) * | 1999-11-16 | 2001-05-25 | Pharmacia & Upjohn Company | Novel g protein-coupled receptors |
| PT1287133E (pt) * | 2000-05-18 | 2007-03-30 | Bayer Healthcare Ag | Regulação do receptor acoplado à proteína g tipo dopamina humano |
| ATE348152T1 (de) * | 2000-12-01 | 2007-01-15 | Astellas Pharma Inc | Verfahren zum screening von diabetes- heilverfahren |
| US20030064381A1 (en) * | 2001-03-07 | 2003-04-03 | Feder John N. | Polynucleotide encoding a novel human G-protein coupled receptor, HGPRBMY26, expressed highly in testis and gastrointestinal tissues |
| WO2002077001A2 (en) * | 2001-03-09 | 2002-10-03 | Tularik Inc. | Novel receptors |
| US7053121B2 (en) * | 2001-03-19 | 2006-05-30 | Trustees Of The University Of Pennsylvania | Compositions and methods for regulating circadian rhythms |
| AU2002318168B2 (en) | 2002-02-25 | 2007-12-13 | Vaxiion Therapeutics, Llc | Minicell compositions and methods |
| US20050191612A1 (en) * | 2002-09-11 | 2005-09-01 | Takahide Ohishi | Method of screening insulin content enhancer |
| US20030143590A1 (en) * | 2002-11-18 | 2003-07-31 | Shyam Ramakrishnan | Regulation of human dopamine-like g protein- coupled receptor |
| WO2004099419A2 (en) * | 2003-04-30 | 2004-11-18 | Arena Pharmaceuticals, Inc. | Methods and compositions for identifying modulators of g protein-coupled receptors |
| US7083933B1 (en) | 2003-05-09 | 2006-08-01 | Prosidion Limited | Methods for identification of modulators of OSGPR116 activity |
| ATE500270T1 (de) * | 2003-05-20 | 2011-03-15 | Univ Glasgow | Materialien und methoden die sich auf g-protein gekoppelte rezeptor oligomere beziehen |
| US7309589B2 (en) * | 2004-08-20 | 2007-12-18 | Vironix Llc | Sensitive detection of bacteria by improved nested polymerase chain reaction targeting the 16S ribosomal RNA gene and identification of bacterial species by amplicon sequencing |
| WO2006067531A1 (en) * | 2004-12-24 | 2006-06-29 | Prosidion Ltd | G-protein coupled receptor (gpr116) agonists and use thereof for treating obesity and diabetes |
| DOP2006000008A (es) * | 2005-01-10 | 2006-08-31 | Arena Pharm Inc | Terapia combinada para el tratamiento de la diabetes y afecciones relacionadas y para el tratamiento de afecciones que mejoran mediante un incremento de la concentración sanguínea de glp-1 |
| US7306203B2 (en) * | 2005-01-28 | 2007-12-11 | Platt Robert E | Post assembly and spacer for use therewith |
| WO2006113236A2 (en) * | 2005-04-14 | 2006-10-26 | Cornell Research Foundation, Inc. | Novel chemical inhibitors of neutrophil activation through the sac-dependent pathway |
| WO2007003960A1 (en) * | 2005-06-30 | 2007-01-11 | Prosidion Limited | Gpcr agonists |
| NZ564759A (en) | 2005-06-30 | 2011-08-26 | Prosidion Ltd | GPCR agonists |
| ES2354390T3 (es) * | 2006-04-11 | 2011-03-14 | Arena Pharmaceuticals, Inc. | Procedimientos de uso del receptor gpr119 para identificar compuestos útiles para aumentar la masa ósea en un individuo. |
| PE20071221A1 (es) * | 2006-04-11 | 2007-12-14 | Arena Pharm Inc | Agonistas del receptor gpr119 en metodos para aumentar la masa osea y para tratar la osteoporosis y otras afecciones caracterizadas por masa osea baja, y la terapia combinada relacionada a estos agonistas |
| US7638541B2 (en) | 2006-12-28 | 2009-12-29 | Metabolex Inc. | 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine |
| CL2008000018A1 (es) * | 2007-01-04 | 2008-08-01 | Prosidion Ltd | Compuestos derivados de heterociclos de nitrogeno y oxigeno, agonistas de gpcr; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento de la obesidad, diabetes, sindrome metabolico, hiperlipidemia, toleranci |
| AR064736A1 (es) | 2007-01-04 | 2009-04-22 | Prosidion Ltd | Agonistas de gpcr |
| WO2008081208A1 (en) | 2007-01-04 | 2008-07-10 | Prosidion Limited | Piperidine gpcr agonists |
| GB0700122D0 (en) | 2007-01-04 | 2007-02-14 | Prosidion Ltd | GPCR agonists |
| BRPI0806498A2 (pt) * | 2007-01-04 | 2014-04-22 | Prosidion Ltd | Agonistas gpcr piperidina |
| JP5489997B2 (ja) | 2007-07-19 | 2014-05-14 | シマベイ セラピューティクス, インコーポレーテッド | 糖尿病および代謝疾患の治療のためのRUP3またはGPRl19受容体のアゴニストとしてのN−アザ環状置換ピロール、ピラゾール、イミダゾール、トリアゾールおよびテトラゾール誘導体 |
| WO2009034388A1 (en) | 2007-09-10 | 2009-03-19 | Prosidion Limited | Compounds for the treatment of metabolic disorders |
| CA2697551C (en) * | 2007-09-20 | 2013-03-12 | Irm Llc | Piperidine derivatives as modulators of gpr119 activity |
| GB0720389D0 (en) | 2007-10-18 | 2008-11-12 | Prosidion Ltd | G-Protein Coupled Receptor Agonists |
| GB0720390D0 (en) | 2007-10-18 | 2007-11-28 | Prosidion Ltd | G-Protein coupled receptor agonists |
| TW201002705A (en) * | 2008-03-31 | 2010-01-16 | Metabolex Inc | Oxymethylene aryl compounds and uses thereof |
| EP2146210A1 (de) | 2008-04-07 | 2010-01-20 | Arena Pharmaceuticals, Inc. | Verfahren zur Verwendung eines AG-Protein-gekoppelten Rezeptors zur Identifikation von Peptid-YY (PPY)-Sekretagogen sowie Verbindungen zur Behandlung durch PYY modulierter Leiden |
| GB0812649D0 (en) * | 2008-07-10 | 2008-08-20 | Prosidion Ltd | Compounds |
| GB0812642D0 (en) * | 2008-07-10 | 2008-08-20 | Prosidion Ltd | Compounds |
| GB0812648D0 (en) * | 2008-07-10 | 2008-08-20 | Prosidion Ltd | Compounds |
| ES2387865T3 (es) * | 2008-07-10 | 2012-10-03 | Prosidion Ltd | Agonistas de GPCR de piperidina |
| US20110160222A1 (en) * | 2008-11-26 | 2011-06-30 | Metabolex, Inc. | Modulators of glucose homeostasis for the treatment of diabetes and metabolic disorders |
| WO2010084512A1 (en) | 2008-12-24 | 2010-07-29 | Cadila Healthcare Limited | Novel oxime derivatives |
| GB0904287D0 (en) | 2009-03-12 | 2009-04-22 | Prosidion Ltd | Compounds for the treatment of metabolic disorders |
| GB0904285D0 (en) | 2009-03-12 | 2009-04-22 | Prosidion Ltd | Compounds for the treatment of metabolic disorders |
| GB0904284D0 (en) | 2009-03-12 | 2009-04-22 | Prosidion Ltd | Compounds for the treatment of metabolic disorders |
| US20120094935A1 (en) * | 2009-04-09 | 2012-04-19 | West Anthony P | Methods for creating or identifying compounds that bind tumor necrosis factor alpha |
| UA104188C2 (en) | 2009-06-18 | 2014-01-10 | Кадила Хелткере Лимитед | Gpr 119 agonists |
| JP2012530758A (ja) * | 2009-06-24 | 2012-12-06 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 新規化合物、医薬組成物及びそれに関する方法 |
| NZ596445A (en) * | 2009-06-24 | 2013-04-26 | Boehringer Ingelheim Int | New compounds, pharmaceutical composition and methods relating thereto |
| JP2012228181A (ja) * | 2009-09-02 | 2012-11-22 | Panasonic Corp | 脂質二重膜の産生方法、化学物質を検知可能とする方法、細胞、カリウムイオンを輸送する方法、および化学物質を検知または定量する方法 |
| JP2012228180A (ja) * | 2009-09-02 | 2012-11-22 | Panasonic Corp | 脂質二重膜の産生方法、化学物質を検知可能とする方法、細胞、カリウムイオンを輸送する方法、および化学物質を検知または定量する方法 |
| WO2011041154A1 (en) * | 2009-10-01 | 2011-04-07 | Metabolex, Inc. | Substituted tetrazol-1-yl-phenoxymethyl-thiazol-2-yl-piperidinyl-pyrimidine salts |
| GB201006167D0 (en) | 2010-04-14 | 2010-05-26 | Prosidion Ltd | Compounds for the treatment of metabolic disorders |
| GB201006166D0 (en) | 2010-04-14 | 2010-05-26 | Prosidion Ltd | Compounds for the treatment of metabolic disorders |
| TW201209054A (en) | 2010-05-28 | 2012-03-01 | Prosidion Ltd | Novel compounds |
| EP2585048B1 (de) | 2010-06-23 | 2018-04-11 | CymaBay Therapeutics, Inc. | Zusammensetzungen von 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidin |
| AU2011311183B2 (en) | 2010-10-08 | 2014-09-25 | Cadila Healthcare Limited | Novel GPR 119 agonists |
| GB201114389D0 (en) | 2011-08-22 | 2011-10-05 | Prosidion Ltd | Novel compounds |
| WO2012066077A1 (en) | 2010-11-18 | 2012-05-24 | Prosidion Limited | 1,4 di substituted pyrrolidine - 3 - yl -amine derivatives and their use for the treatment of metabolic disorders |
| AU2012267556B9 (en) | 2011-06-09 | 2017-05-11 | Rhizen Pharmaceuticals Sa | Novel compounds as modulators of GPR-119 |
| EP3493807A1 (de) | 2016-08-03 | 2019-06-12 | CymaBay Therapeutics, Inc. | Oxymethylenarylverbindungen zur behandlung von entzündlichen gastrointestinalen krankheiten oder gastrointestinalen leiden |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5053337A (en) | 1989-10-30 | 1991-10-01 | Neurogenetic Corporation | DNA encoding an α2B -adrenergic receptor |
| US5661024A (en) | 1989-10-31 | 1997-08-26 | Synaptic Pharmaceutical Corporation | DNA encoding a human serotonic (5-HT2) receptor and uses thereof |
| US5155218A (en) | 1990-05-08 | 1992-10-13 | Neurogenetic Corporation | Dna encoding human 5-ht1d receptors |
| ATE292175T1 (de) | 1991-12-02 | 2005-04-15 | Synaptic Pharma Corp | Dna kodierend für den menschlichen 5-ht 1e- rezeptor und seine verwendungen |
| US5360735A (en) | 1992-01-08 | 1994-11-01 | Synaptic Pharmaceutical Corporation | DNA encoding a human 5-HT1F receptor, vectors, and host cells |
| WO1993025677A1 (en) | 1992-06-12 | 1993-12-23 | Garvan Institute Of Medical Research | DNA SEQUENCES ENCODING THE HUMAN A1, A2a and A2b ADENOSINE RECEPTORS |
| EP0663014B1 (de) | 1992-09-25 | 2004-08-18 | Synaptic Pharmaceutical Corporation | Für menschliche alpha-1-adrenerge rezeptoren kodierende dns und ihre verwendung |
| US5472866A (en) | 1992-12-24 | 1995-12-05 | Synaptic Pharmaceutical Corporation | DNA encoding 5-HT4A serotonin receptors |
| US5516653A (en) | 1993-12-28 | 1996-05-14 | Synaptic Pharmaceutical Corporation | DNA encoding a human neuropeptide Y/peptide YY/pancreatic polypeptide receptor (Y4) and uses thereof |
| US5545549A (en) | 1994-02-03 | 1996-08-13 | Synaptic Pharmaceutical Corporation | DNA encoding a human neuropeptide Y/peptide YY (Y2) receptor and uses thereof |
| US5602024A (en) | 1994-12-02 | 1997-02-11 | Synaptic Pharmaceutical Corporation | DNA encoding a hypothalamic atypical neuropeptide Y/peptide YY receptor (Y5) and uses thereof |
| WO2000022131A2 (en) | 1998-10-13 | 2000-04-20 | Arena Pharmaceuticals, Inc. | Non-endogenous, constitutively activated human g protein-coupled receptors |
| DK1133559T3 (da) | 1998-11-20 | 2006-04-10 | Arena Pharm Inc | Human-G-protein-koblet orphan receptor RUP3 |
| US20030017528A1 (en) * | 1998-11-20 | 2003-01-23 | Ruoping Chen | Human orphan G protein-coupled receptors |
| US6221660B1 (en) | 1999-02-22 | 2001-04-24 | Synaptic Pharmaceutical Corporation | DNA encoding SNORF25 receptor |
| EP1235860A2 (de) | 1999-12-10 | 2002-09-04 | Incyte Genomics, Inc. | G-protein gekoppelte rezeptoren |
-
1999
- 1999-08-13 US US09/387,699 patent/US6221660B1/en not_active Expired - Lifetime
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2000
- 2000-02-22 PT PT00908748T patent/PT1075493E/pt unknown
- 2000-02-22 JP JP2000601126A patent/JP2002539772A/ja not_active Withdrawn
- 2000-02-22 ES ES00908748T patent/ES2312333T3/es not_active Expired - Lifetime
- 2000-02-22 DE DE60039948T patent/DE60039948D1/de not_active Expired - Lifetime
- 2000-02-22 AU AU30035/00A patent/AU777247B2/en not_active Withdrawn - After Issue
- 2000-02-22 WO PCT/US2000/004413 patent/WO2000050562A2/en not_active Ceased
- 2000-02-22 DK DK00908748T patent/DK1075493T3/da active
- 2000-02-22 EP EP00908748A patent/EP1075493B1/de not_active Revoked
- 2000-02-22 AT AT00908748T patent/ATE405589T1/de active
- 2000-02-22 CA CA002362906A patent/CA2362906A1/en not_active Abandoned
- 2000-08-17 US US09/641,259 patent/US6468756B1/en not_active Expired - Fee Related
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2002
- 2002-10-22 US US10/278,437 patent/US7416848B2/en not_active Expired - Fee Related
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- 2008-11-12 CY CY20081101291T patent/CY1108503T1/el unknown
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|---|---|
| AU3003500A (en) | 2000-09-14 |
| PT1075493E (pt) | 2008-12-03 |
| WO2000050562A3 (en) | 2000-12-14 |
| JP2010063457A (ja) | 2010-03-25 |
| US7416848B2 (en) | 2008-08-26 |
| AU777247B2 (en) | 2004-10-07 |
| WO2000050562A2 (en) | 2000-08-31 |
| CA2362906A1 (en) | 2000-08-31 |
| EP1075493A2 (de) | 2001-02-14 |
| US6221660B1 (en) | 2001-04-24 |
| JP2002539772A (ja) | 2002-11-26 |
| EP1075493B1 (de) | 2008-08-20 |
| DE60039948D1 (de) | 2008-10-02 |
| US20030139590A1 (en) | 2003-07-24 |
| ES2312333T3 (es) | 2009-03-01 |
| US6468756B1 (en) | 2002-10-22 |
| DK1075493T3 (da) | 2009-01-12 |
| EP1075493A4 (de) | 2004-10-27 |
| CY1108503T1 (el) | 2014-04-09 |
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